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The map label for this gene is ribB [H]

Identifier: 182682361

GI number: 182682361

Start: 2047104

End: 2048237

Strand: Reverse

Name: ribB [H]

Synonym: XfasM23_1846

Alternate gene names: 182682361

Gene position: 2048237-2047104 (Counterclockwise)

Preceding gene: 182682362

Following gene: 182682360

Centisome position: 80.78

GC content: 56.53

Gene sequence:

>1134_bases
ATGAATTCTTTTGCGGCGGTTCCGGTGTTGATTGAGGAGATTCGTGCTGGTCGCATGGTGGTGATTGTTGATGATGAGGA
TCGTGAAAATGAGGGCGATCTCATTATGGCTGCGGAGTTGGTTGCACCGAAGGACATTAATTTCATGGTGACGCACGCGC
GTGGCTTGGTCTGCTTGTCGTTGACACGTGAGCGCTGTGCCCAGATTGGGCTGTCGCCGATGGTGCAGCGCAACACGACG
CGGTTTCAGACGAATTTCACGGTCAGCATTGAGGCTGCTGAGGGTTTGACGACCGGCATTTCCGCGTATGACCGTGCGCA
TACCATCCGTACCGCAGTGCGTCCAAACGCTAAGCCATCTGACCTGCATCAACCCGGCCACATCTTCCCCTTGATCGCGC
AGCCGGGTGGGGTACTTACCCGTGCTGGTCACACTGAAGCGGCGAGTGATTTGCCAATGTTGGCTGGCCTGGAACCGGCT
GGGGTGCTTGTGGAGATTATGAATGCTGACGGGACGATGGCGCGTCGCCCGCAGTTGGAGGTATTTGCGCAGCAACATGG
GTTGAAGATAGGTTCGATCGCTGATTTGATCGCTTACCGTCTTGCCAATGAACACACTGTTGAGCGTGTGGACGAGCGTG
TCATTGAGACCGAGTATGGTTCGTTCTTATTGGTGACTTATCGTGATCGTATCGCCCATGACCTGCATTTTGCGTTGGTG
CGTGGCACTTTGGACGCTTCGATCCCAACTCTTGTCCGGGTACAGGTAGAGAATCCTCTGGCGGATATGTTGCACTGGCG
CCGTGAAGACTTTGGTGTGGCTGCATCGGATGCATTGCGCATGATCGCTGCGGCTGAGCGTGGTGTGATGGTGATGTTGG
CAGCGCCACGAGATAGTGATGTCTTGTTGGCAAGGCTCCGGAGTGAGCCGGAGGTGGTTTCCAATGTGAAGGATGTAGGG
CAGTGGCGGCGTAACGGTGCTGGGGGACAGATTCTGGCTGATCTTGGCTTGGCGAAGCTGCGCGTGTTGGGTACGCCGCG
TCGCCAGATTGCCTTGGCCGGATTTGGTCTGGAAGTGCTAGAGTATGTGGAATGCCGCGGCGGGGTCCCGGTCCCCTCCC
AGGGTGTCGATTGA

Upstream 100 bases:

>100_bases
ATACCCGGTTTTCTCGTACGGTGATCGGTGAGGCAGTGAATCTGGAGATTGATTTAATTGCACGCTACGTCGAACGTTTG
TTGGTGACGGGGAACAAGCA

Downstream 100 bases:

>100_bases
ATTTTTCCTCATTCCGGAGTCAAACCTTAGATGAGCCACTACGAAGGCGATCTTCGCCCCGCAGGTGCGCGCTTTGTGAT
CGTCTGCAGCCGCTGGAACG

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MNSFAAVPVLIEEIRAGRMVVIVDDEDRENEGDLIMAAELVAPKDINFMVTHARGLVCLSLTRERCAQIGLSPMVQRNTT
RFQTNFTVSIEAAEGLTTGISAYDRAHTIRTAVRPNAKPSDLHQPGHIFPLIAQPGGVLTRAGHTEAASDLPMLAGLEPA
GVLVEIMNADGTMARRPQLEVFAQQHGLKIGSIADLIAYRLANEHTVERVDERVIETEYGSFLLVTYRDRIAHDLHFALV
RGTLDASIPTLVRVQVENPLADMLHWRREDFGVAASDALRMIAAAERGVMVMLAAPRDSDVLLARLRSEPEVVSNVKDVG
QWRRNGAGGQILADLGLAKLRVLGTPRRQIALAGFGLEVLEYVECRGGVPVPSQGVD

Sequences:

>Translated_377_residues
MNSFAAVPVLIEEIRAGRMVVIVDDEDRENEGDLIMAAELVAPKDINFMVTHARGLVCLSLTRERCAQIGLSPMVQRNTT
RFQTNFTVSIEAAEGLTTGISAYDRAHTIRTAVRPNAKPSDLHQPGHIFPLIAQPGGVLTRAGHTEAASDLPMLAGLEPA
GVLVEIMNADGTMARRPQLEVFAQQHGLKIGSIADLIAYRLANEHTVERVDERVIETEYGSFLLVTYRDRIAHDLHFALV
RGTLDASIPTLVRVQVENPLADMLHWRREDFGVAASDALRMIAAAERGVMVMLAAPRDSDVLLARLRSEPEVVSNVKDVG
QWRRNGAGGQILADLGLAKLRVLGTPRRQIALAGFGLEVLEYVECRGGVPVPSQGVD
>Mature_377_residues
MNSFAAVPVLIEEIRAGRMVVIVDDEDRENEGDLIMAAELVAPKDINFMVTHARGLVCLSLTRERCAQIGLSPMVQRNTT
RFQTNFTVSIEAAEGLTTGISAYDRAHTIRTAVRPNAKPSDLHQPGHIFPLIAQPGGVLTRAGHTEAASDLPMLAGLEPA
GVLVEIMNADGTMARRPQLEVFAQQHGLKIGSIADLIAYRLANEHTVERVDERVIETEYGSFLLVTYRDRIAHDLHFALV
RGTLDASIPTLVRVQVENPLADMLHWRREDFGVAASDALRMIAAAERGVMVMLAAPRDSDVLLARLRSEPEVVSNVKDVG
QWRRNGAGGQILADLGLAKLRVLGTPRRQIALAGFGLEVLEYVECRGGVPVPSQGVD

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=201, Percent_Identity=53.2338308457711, Blast_Score=218, Evalue=7e-58,
Organism=Saccharomyces cerevisiae, GI6320695, Length=206, Percent_Identity=39.8058252427184, Blast_Score=152, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 41080; Mature: 41080

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFAAVPVLIEEIRAGRMVVIVDDEDRENEGDLIMAAELVAPKDINFMVTHARGLVCLS
CCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEECCCEEEEH
LTRERCAQIGLSPMVQRNTTRFQTNFTVSIEAAEGLTTGISAYDRAHTIRTAVRPNAKPS
HHHHHHHHCCCCCHHHCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCC
DLHQPGHIFPLIAQPGGVLTRAGHTEAASDLPMLAGLEPAGVLVEIMNADGTMARRPQLE
CCCCCCCEEEEEECCCCEEEECCCCCCCCCCCHHCCCCCCCEEEEEECCCCCCCCCCHHH
VFAQQHGLKIGSIADLIAYRLANEHTVERVDERVIETEYGSFLLVTYRDRIAHDLHFALV
HHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHH
RGTLDASIPTLVRVQVENPLADMLHWRREDFGVAASDALRMIAAAERGVMVMLAAPRDSD
HCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCH
VLLARLRSEPEVVSNVKDVGQWRRNGAGGQILADLGLAKLRVLGTPRRQIALAGFGLEVL
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEHHCHHHEEEECCCCHHEEEECCCHHHH
EYVECRGGVPVPSQGVD
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNSFAAVPVLIEEIRAGRMVVIVDDEDRENEGDLIMAAELVAPKDINFMVTHARGLVCLS
CCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEECCCEEEEH
LTRERCAQIGLSPMVQRNTTRFQTNFTVSIEAAEGLTTGISAYDRAHTIRTAVRPNAKPS
HHHHHHHHCCCCCHHHCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCC
DLHQPGHIFPLIAQPGGVLTRAGHTEAASDLPMLAGLEPAGVLVEIMNADGTMARRPQLE
CCCCCCCEEEEEECCCCEEEECCCCCCCCCCCHHCCCCCCCEEEEEECCCCCCCCCCHHH
VFAQQHGLKIGSIADLIAYRLANEHTVERVDERVIETEYGSFLLVTYRDRIAHDLHFALV
HHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHH
RGTLDASIPTLVRVQVENPLADMLHWRREDFGVAASDALRMIAAAERGVMVMLAAPRDSD
HCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCH
VLLARLRSEPEVVSNVKDVGQWRRNGAGGQILADLGLAKLRVLGTPRRQIALAGFGLEVL
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEHHCHHHEEEECCCCHHEEEECCCHHHH
EYVECRGGVPVPSQGVD
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339274 [H]