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The map label for this gene is erpA

Identifier: 182682281

GI number: 182682281

Start: 1952238

End: 1952624

Strand: Reverse

Name: erpA

Synonym: XfasM23_1763

Alternate gene names: 182682281

Gene position: 1952624-1952238 (Counterclockwise)

Preceding gene: 182682282

Following gene: 182682279

Centisome position: 77.01

GC content: 47.8

Gene sequence:

>387_bases
ATGACTATGCTCATTTCTTTGCCCACGGCACCATCAGTGCCTAACTATCAGTCGCTGGAGCGTCCATTGAATTTCACTAT
GGCTGCAGCAGCCAAAGTCCGTGAATTGATACAGGAAGAGAACAACGCCGATTTGGCGTTGCGTGTTTACATCCAGGGTG
GGGGGTGTTCTGGTTTCCAGTACGGCTTTGAGTTTGACGAAAATCGCGCTGATGATGATTTAGCGTTGGAGACAGATGGT
GTTGTGTTATTGGTTGATCCACTCAGTCTGCAGTATCTGTTAGGTGCAGAGGTCGACTACACTGAGAGCCTCACTGGTGC
TAAGTTTGTGATTCGAAATCCCAATGCTAAGACTACCTGTGGTTGTGGCAGTAGTTTCAGTGTTTGA

Upstream 100 bases:

>100_bases
TTGCCGCCTCCAGATGAACCCTTGTCAACGCTGGAATTAGAGACATCTGTTGCAGCAGGTCCTTGATTCGCCCTTCCTTT
GACCTCATGCAGGCTATAGT

Downstream 100 bases:

>100_bases
CGTGCTTAAGATTTCTCGGTCTCAGTATTAGTTCGGTTGGCAAGGGGGCCTTGCTTATACGGCTCAAACCCGCCCATTGA
CAAAGTCTGATATCAGTGTT

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MTMLISLPTAPSVPNYQSLERPLNFTMAAAAKVRELIQEENNADLALRVYIQGGGCSGFQYGFEFDENRADDDLALETDG
VVLLVDPLSLQYLLGAEVDYTESLTGAKFVIRNPNAKTTCGCGSSFSV

Sequences:

>Translated_128_residues
MTMLISLPTAPSVPNYQSLERPLNFTMAAAAKVRELIQEENNADLALRVYIQGGGCSGFQYGFEFDENRADDDLALETDG
VVLLVDPLSLQYLLGAEVDYTESLTGAKFVIRNPNAKTTCGCGSSFSV
>Mature_127_residues
TMLISLPTAPSVPNYQSLERPLNFTMAAAAKVRELIQEENNADLALRVYIQGGGCSGFQYGFEFDENRADDDLALETDGV
VLLVDPLSLQYLLGAEVDYTESLTGAKFVIRNPNAKTTCGCGSSFSV

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=83, Percent_Identity=45.7831325301205, Blast_Score=80, Evalue=4e-16,
Organism=Homo sapiens, GI52426768, Length=119, Percent_Identity=32.7731092436975, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1786351, Length=107, Percent_Identity=63.5514018691589, Blast_Score=150, Evalue=2e-38,
Organism=Escherichia coli, GI1788877, Length=101, Percent_Identity=36.6336633663366, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1787974, Length=106, Percent_Identity=34.9056603773585, Blast_Score=69, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193209025, Length=111, Percent_Identity=36.9369369369369, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25146411, Length=106, Percent_Identity=37.7358490566038, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71998452, Length=111, Percent_Identity=38.7387387387387, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323001, Length=82, Percent_Identity=39.0243902439024, Blast_Score=74, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=45.7831325301205, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=35.8490566037736, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_XYLF2 (B2I891)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830441.1
- ProteinModelPortal:   B2I891
- SMR:   B2I891
- GeneID:   6203004
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1763
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- ProtClustDB:   PRK13623
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 13862; Mature: 13731

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMLISLPTAPSVPNYQSLERPLNFTMAAAAKVRELIQEENNADLALRVYIQGGGCSGFQ
CEEEEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCC
YGFEFDENRADDDLALETDGVVLLVDPLSLQYLLGAEVDYTESLTGAKFVIRNPNAKTTC
CCEECCCCCCCCCEEEECCCEEEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCEE
GCGSSFSV
CCCCCCCC
>Mature Secondary Structure 
TMLISLPTAPSVPNYQSLERPLNFTMAAAAKVRELIQEENNADLALRVYIQGGGCSGFQ
EEEEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCC
YGFEFDENRADDDLALETDGVVLLVDPLSLQYLLGAEVDYTESLTGAKFVIRNPNAKTTC
CCEECCCCCCCCCEEEECCCEEEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCEE
GCGSSFSV
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA