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The map label for this gene is engA

Identifier: 182682229

GI number: 182682229

Start: 1890707

End: 1892104

Strand: Reverse

Name: engA

Synonym: XfasM23_1711

Alternate gene names: 182682229

Gene position: 1892104-1890707 (Counterclockwise)

Preceding gene: 182682230

Following gene: 182682227

Centisome position: 74.62

GC content: 53.15

Gene sequence:

>1398_bases
ATGCTCCCTTTGGTCGCCCTGGTTGGACGGCCGAACGTTGGTAAGTCCACCCTGTTTAACGCGTTGACGCTGACGCGTGA
TGCACTTGTACATGACCAACCCGGTGTCACCCGTGATCGCCACTATGGTGTATGCCGTATTGATGGGCAGCCTTTGTTTG
CTGTCGTCGATACTGGTGGCATGGTTGGTAAGGAAGATGGCTTGGCTGGTGCTACGGCGCGTCAAGCACGTCTTGCTGTG
GCTGAAGCTGATGTGGTGTTGTTTGTGGTCAACGTGCGTGAAGGTGCGTCTGCGCTTGACGACGATATCCTTGCTTGGTT
ACGCAAGCTATCGCAGCCTACATTGTTGGTGATCAATAAAATTGATGGTGTGAGTGATACCACAGTGCATTCGGAGTTCG
CTCACTACGGCTTTTCCGACGTGGTTCCTGTTTCTGCTGCGCATCGTCAAGGCTTGGATGACCTTATTGAACAGGTGCTT
GCGTGGCTGCCTGAACGCAGTATTGGCGAGGCATTTAATGAAGATTCAGAGCGCATCCATATTGCTTTTGTCGGTCGACC
GAATGTCGGTAAATCGACACTAGTGAACCGCCTGCTTGGTGAGGAGCGGATGATTGTCTCGGATGTGCCTGGCACAACCC
GCGATTCCATTACAGTTGATTTGGAGCGCGATGAATTACGGTACCGTTTGGTCGATACCGCGGGCTTACGACGCAAATCG
AAGGTTGAAGAGGCAGTCGAAAAATTCAGTGCCTTTAAGACCCTACAGGCGATCGAACAATGCCAAGTTGCGGTGTTGCT
GTTGGATGCCGGTGAGGGTGTGACTGACCAGGATGCTACCGTGCTTGCCGCCATCTTGGATGCGGGCAAGGCCCTGGTCG
TGGCGATGAATAAATGGGATGGCCTCGCTACTTACCAGAGAGAACAAGCCGAGGACTTGCTCTCGCGTAAACTCGGCTTT
GTCAATTGGGCTGAGGTGGTGCGTCTTTCTGCCAAACATGGCTCGGGCTTACGTGAATTATTCAGAGCTATTCATCGTGC
TCATGTTTCGGCGCTGCGTCAGTTCAGCACCAGCGAGGTGAATAAAGCGCTGGAGATCGCCTACCAAACCGCGCCGCCGC
CGAGCATTCGAGGCCATGTGTCCAAATTACGTTATGTCCATCCGGCTGGAAGTAATCCGCCAACCTTCATCGTCCATGGA
ACCCGCCTGAAGGTGTTACCGGATACGTACAAACGTTACCTGGAGAATTTCTTCCGTAAGCGCTTCAAACTGGTTGGCAC
CCCGGTGCGTTTCCTGTTCAGAGAAGGTGACAACCCTTATGAAGGCAGGAAGAACGTATTGAGCGAACGCCAGATCCAGC
GCAGACGCCGTTTGATGCGCCATGTGAAGCGTAAATAG

Upstream 100 bases:

>100_bases
CCTGTCGTCGCTGACAATGTGCTTCTGGTGCAGAGTAGTAATGGAAAGCTCGCTGCTTTTCGTCTGATGCAATAACAATA
ACTACGGATGTTGATGCGAT

Downstream 100 bases:

>100_bases
TGAGGCTGAGTGGCCTTGTTATATGAAATGCTGCGTGGGATCGTGTCGATGCTTCATGCTTCAGTATCTAGGCTAGGGAA
GGGATGATGCCTTTATTGCT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MLPLVALVGRPNVGKSTLFNALTLTRDALVHDQPGVTRDRHYGVCRIDGQPLFAVVDTGGMVGKEDGLAGATARQARLAV
AEADVVLFVVNVREGASALDDDILAWLRKLSQPTLLVINKIDGVSDTTVHSEFAHYGFSDVVPVSAAHRQGLDDLIEQVL
AWLPERSIGEAFNEDSERIHIAFVGRPNVGKSTLVNRLLGEERMIVSDVPGTTRDSITVDLERDELRYRLVDTAGLRRKS
KVEEAVEKFSAFKTLQAIEQCQVAVLLLDAGEGVTDQDATVLAAILDAGKALVVAMNKWDGLATYQREQAEDLLSRKLGF
VNWAEVVRLSAKHGSGLRELFRAIHRAHVSALRQFSTSEVNKALEIAYQTAPPPSIRGHVSKLRYVHPAGSNPPTFIVHG
TRLKVLPDTYKRYLENFFRKRFKLVGTPVRFLFREGDNPYEGRKNVLSERQIQRRRRLMRHVKRK

Sequences:

>Translated_465_residues
MLPLVALVGRPNVGKSTLFNALTLTRDALVHDQPGVTRDRHYGVCRIDGQPLFAVVDTGGMVGKEDGLAGATARQARLAV
AEADVVLFVVNVREGASALDDDILAWLRKLSQPTLLVINKIDGVSDTTVHSEFAHYGFSDVVPVSAAHRQGLDDLIEQVL
AWLPERSIGEAFNEDSERIHIAFVGRPNVGKSTLVNRLLGEERMIVSDVPGTTRDSITVDLERDELRYRLVDTAGLRRKS
KVEEAVEKFSAFKTLQAIEQCQVAVLLLDAGEGVTDQDATVLAAILDAGKALVVAMNKWDGLATYQREQAEDLLSRKLGF
VNWAEVVRLSAKHGSGLRELFRAIHRAHVSALRQFSTSEVNKALEIAYQTAPPPSIRGHVSKLRYVHPAGSNPPTFIVHG
TRLKVLPDTYKRYLENFFRKRFKLVGTPVRFLFREGDNPYEGRKNVLSERQIQRRRRLMRHVKRK
>Mature_465_residues
MLPLVALVGRPNVGKSTLFNALTLTRDALVHDQPGVTRDRHYGVCRIDGQPLFAVVDTGGMVGKEDGLAGATARQARLAV
AEADVVLFVVNVREGASALDDDILAWLRKLSQPTLLVINKIDGVSDTTVHSEFAHYGFSDVVPVSAAHRQGLDDLIEQVL
AWLPERSIGEAFNEDSERIHIAFVGRPNVGKSTLVNRLLGEERMIVSDVPGTTRDSITVDLERDELRYRLVDTAGLRRKS
KVEEAVEKFSAFKTLQAIEQCQVAVLLLDAGEGVTDQDATVLAAILDAGKALVVAMNKWDGLATYQREQAEDLLSRKLGF
VNWAEVVRLSAKHGSGLRELFRAIHRAHVSALRQFSTSEVNKALEIAYQTAPPPSIRGHVSKLRYVHPAGSNPPTFIVHG
TRLKVLPDTYKRYLENFFRKRFKLVGTPVRFLFREGDNPYEGRKNVLSERQIQRRRRLMRHVKRK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=489, Percent_Identity=46.8302658486708, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI2367268, Length=191, Percent_Identity=32.4607329842932, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788919, Length=180, Percent_Identity=32.7777777777778, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=180, Percent_Identity=29.4444444444444, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_XYLF2 (B2I7V0)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830389.1
- ProteinModelPortal:   B2I7V0
- SMR:   B2I7V0
- GeneID:   6203773
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1711
- HOGENOM:   HBG592135
- OMA:   KCEKAFD
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 51787; Mature: 51787

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPLVALVGRPNVGKSTLFNALTLTRDALVHDQPGVTRDRHYGVCRIDGQPLFAVVDTGG
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEEEECCC
MVGKEDGLAGATARQARLAVAEADVVLFVVNVREGASALDDDILAWLRKLSQPTLLVINK
CCCCCCCCCCCHHHHHHHHEEECCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEC
IDGVSDTTVHSEFAHYGFSDVVPVSAAHRQGLDDLIEQVLAWLPERSIGEAFNEDSERIH
CCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCHHHHHHCCCCCEEE
IAFVGRPNVGKSTLVNRLLGEERMIVSDVPGTTRDSITVDLERDELRYRLVDTAGLRRKS
EEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEHHHHHEEEHHHHCCCHHH
KVEEAVEKFSAFKTLQAIEQCQVAVLLLDAGEGVTDQDATVLAAILDAGKALVVAMNKWD
HHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCC
GLATYQREQAEDLLSRKLGFVNWAEVVRLSAKHGSGLRELFRAIHRAHVSALRQFSTSEV
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
NKALEIAYQTAPPPSIRGHVSKLRYVHPAGSNPPTFIVHGTRLKVLPDTYKRYLENFFRK
HHHHHHHCCCCCCCCHHHHHHHHEEECCCCCCCCEEEEECCEEEECCHHHHHHHHHHHHH
RFKLVGTPVRFLFREGDNPYEGRKNVLSERQIQRRRRLMRHVKRK
HHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLPLVALVGRPNVGKSTLFNALTLTRDALVHDQPGVTRDRHYGVCRIDGQPLFAVVDTGG
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEEEECCC
MVGKEDGLAGATARQARLAVAEADVVLFVVNVREGASALDDDILAWLRKLSQPTLLVINK
CCCCCCCCCCCHHHHHHHHEEECCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEC
IDGVSDTTVHSEFAHYGFSDVVPVSAAHRQGLDDLIEQVLAWLPERSIGEAFNEDSERIH
CCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCHHHHHHCCCCCEEE
IAFVGRPNVGKSTLVNRLLGEERMIVSDVPGTTRDSITVDLERDELRYRLVDTAGLRRKS
EEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEHHHHHEEEHHHHCCCHHH
KVEEAVEKFSAFKTLQAIEQCQVAVLLLDAGEGVTDQDATVLAAILDAGKALVVAMNKWD
HHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCC
GLATYQREQAEDLLSRKLGFVNWAEVVRLSAKHGSGLRELFRAIHRAHVSALRQFSTSEV
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
NKALEIAYQTAPPPSIRGHVSKLRYVHPAGSNPPTFIVHGTRLKVLPDTYKRYLENFFRK
HHHHHHHCCCCCCCCHHHHHHHHEEECCCCCCCCEEEEECCEEEECCHHHHHHHHHHHHH
RFKLVGTPVRFLFREGDNPYEGRKNVLSERQIQRRRRLMRHVKRK
HHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA