Click here to switch to the map view.

The map label for this gene is dsbD [H]

Identifier: 182682142

GI number: 182682142

Start: 1795084

End: 1797360

Strand: Reverse

Name: dsbD [H]

Synonym: XfasM23_1620

Alternate gene names: 182682142

Gene position: 1797360-1795084 (Counterclockwise)

Preceding gene: 182682143

Following gene: 182682140

Centisome position: 70.88

GC content: 52.22

Gene sequence:

>2277_bases
ATGACGTTCTTGCATCGTTTAGCCACACTATGTGTATTGGCACTGATTTCTTTTCCTGTAGTCGCCGTCAGCGAAACGGA
CCTACTTCCGGTGGAAAAGGCTTTTGTGGTCGGGGTGAAAGCTCTTGATCGCCATCATGTGTTGGTGCATTGGAAGATCG
CCGAGGGTTATTACCTTTACCGACATAGGATTGCGGTGCGGGTCTTGAATGATGGTGTGCTCAAAAGCGATTCCAAGCTG
AATTTGCCAAATGGCTACAGGAAGAATGATTCGTATTTAGGGGACGTTGAAATTTACCGTGGGAGTCTGACCGCGGTGCG
CAGCGTATTGCCTGTGAAAGGTGTGCATAAGCTGACGTTGCAAGTGAACTACCAGGGATGTGCGGATGCCGGTGTGTGTT
ACCCACCACAGGTACGCACGTTGCATGTTGCGTTGCCGACTGATGGTAATGATTTGGATAGAGGAGCTGTGGTTGATAGG
CAGGATAGGGGGAGTGCTGTTGACGCGCGACCATTGCTCAGTGAGATTGTTCCTGGAGTCCGTGCATTGCCGCTTCCAGC
CGAGCAGGCGTTCGGTTTTGAGGCCATCGTTGGTGATGGTAATCATCTGTTGCTGCGTTTTACCCCGGCCAAGGGGTACT
ACCTGTACCGTGACCGCACTTCACTGGCCTTGGAAGGTGATAAGACTGTTCATACGGGTGTGGCGTATTGGCCGCAGGGC
AGTAAGTATCACGATGAGCATTTTGGTGATGTGGTCGTTTACTTCAATCAAATTGAAGTGATGCTGCCGCTACAGCGTGA
TTATTCAGGGCCTATCGCTAATGCGACTCTGGTAGCGACTTTCCAGGGGTGCCAAATTGACGGCATTTGCTATCCGCCGA
TGACTCGTCGGGTGCGTTTGTCTTTGCCTTCTGGAAAGGTCTCCTCGCCGAATCGCGCTAATGCTATACCGTTGATGGGT
AACCATGCCTCTCTCCAGAACCCATTGCGTTTGCCAGGTAGCAACGTCCCGCCGGCCACGGCCAGTCAGTCGGCCGTTTC
GGTTGACAGCGCTTTGGAGAATCATCCCTCGTACAGTGCGAGCAAGTTTTTCATGGCGTTGTCTCTGGCATTAGTCGGTG
GTTTGCTATTGAATTTGTTGCCGTGCGTGTTGCCGGTGTTATCGCTGAAGGTATTAGCGTTGGCTAAAAGCGGTGAGAGC
CGTGCTTGTGCGCGTCGCCATGCCATTTGGTACACAGCCGGCGTATTGCTCTCGTTTGGCGTCATCGGCGGTATCGCGAT
TATGGCGAAGATACTATGGGGCTTTCAGCTTCAGCAGCCTGGCTTTGTGGGTGTATTGGTTTACTTGATGTTTGCCGTTG
GCCTGAGTTTGTCAGGGGTCTTTACCATGAGCAGCACCAAGTTTGGTGCGATAGGTCAGTCATTGATGGCGCGCAGTGGG
TCATTAGGCGATTTCTTCGCTGGGGTGTTGGCTTGTGTGGTGTCCAGTGCCTGCATTGGTCCATTCATGGGCCCTGCGTT
GGTCTACGCCTTCACCGCGCCGCCGTTGTTGGCAATGTTGGTATTCCTTACGCTTGGCTTTGGTTTGGCATTGCCGTTTC
TGTTGCTTGGCTTTGTGCCATCGTTGACACGTCGTTTGCCGACGCCGGGTCCATGGATGCAGACACTGAAATACGTTCTG
GCATTGCCAATGTATTTGACTGCAATCTGGTTATTGTGGGTTCTGGGCAAACAGCGCGGTGTGGATGCACAGTCGTTGCT
GTTGGTTGGCTTGGTCATGTTGGCAATGGGATTGTGTTGGTTCGAGCGCAGCCGTTGGAATGCTGATCGCTGGGGGTTGG
TGCTCTCCAGTGTATTGTTATTGTTGACCTTGTTGCCGCTTTGGGGGGTGACGCAACTGAAGATACCGCATTCGATCCCG
CAGAATGTCAGTAGCGATGAAGTGGCTTACTCGCCGCTGCTTCTGGATCGTTTGCGTGCCGATAACCGTGTTGTTTTTGT
CAATGTGACTGCGGATTGGTGCGTGACCTGCAAGGCGAATGAACGCAATGTGTTGTCCAGTGATGCTTTTCACGATGTGA
TGCATCGGATTGATGCTGTGTATATGAAGGGTGACTGGACTAATGGAGATGCTCAGATTAGTGCGTTTCTAAGCCAGCAT
CAGGCAGTAGGTGTACCGCTGTATGTGGTTTATGGACCAGGTGCACCGCCCAACATTCTTCCCAATGTGTTGACTAAGGA
TGTTGTGGAGGATGCTTTGTTGCGCGCTGCACGTTGA

Upstream 100 bases:

>100_bases
CTTATCGACTGCCGGAGGCAATCGCAGTCCAGGTCAGCGTGGGATTACCTGAGTACTTGACTTGGATTAATACAGAGATT
GACGAGGAATACTCTCTACC

Downstream 100 bases:

>100_bases
GTGCTACGTGTGCTTGCTGATCTTAGTTAATGCGCAAATAGGTCTTTGGAGTCCTTCTTAGTTTTTGGGTGAATGGCAGG
GTGTGGTTTTTGATGTCTGC

Product: cytochrome c biogenesis transmembrane protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 758; Mature: 757

Protein sequence:

>758_residues
MTFLHRLATLCVLALISFPVVAVSETDLLPVEKAFVVGVKALDRHHVLVHWKIAEGYYLYRHRIAVRVLNDGVLKSDSKL
NLPNGYRKNDSYLGDVEIYRGSLTAVRSVLPVKGVHKLTLQVNYQGCADAGVCYPPQVRTLHVALPTDGNDLDRGAVVDR
QDRGSAVDARPLLSEIVPGVRALPLPAEQAFGFEAIVGDGNHLLLRFTPAKGYYLYRDRTSLALEGDKTVHTGVAYWPQG
SKYHDEHFGDVVVYFNQIEVMLPLQRDYSGPIANATLVATFQGCQIDGICYPPMTRRVRLSLPSGKVSSPNRANAIPLMG
NHASLQNPLRLPGSNVPPATASQSAVSVDSALENHPSYSASKFFMALSLALVGGLLLNLLPCVLPVLSLKVLALAKSGES
RACARRHAIWYTAGVLLSFGVIGGIAIMAKILWGFQLQQPGFVGVLVYLMFAVGLSLSGVFTMSSTKFGAIGQSLMARSG
SLGDFFAGVLACVVSSACIGPFMGPALVYAFTAPPLLAMLVFLTLGFGLALPFLLLGFVPSLTRRLPTPGPWMQTLKYVL
ALPMYLTAIWLLWVLGKQRGVDAQSLLLVGLVMLAMGLCWFERSRWNADRWGLVLSSVLLLLTLLPLWGVTQLKIPHSIP
QNVSSDEVAYSPLLLDRLRADNRVVFVNVTADWCVTCKANERNVLSSDAFHDVMHRIDAVYMKGDWTNGDAQISAFLSQH
QAVGVPLYVVYGPGAPPNILPNVLTKDVVEDALLRAAR

Sequences:

>Translated_758_residues
MTFLHRLATLCVLALISFPVVAVSETDLLPVEKAFVVGVKALDRHHVLVHWKIAEGYYLYRHRIAVRVLNDGVLKSDSKL
NLPNGYRKNDSYLGDVEIYRGSLTAVRSVLPVKGVHKLTLQVNYQGCADAGVCYPPQVRTLHVALPTDGNDLDRGAVVDR
QDRGSAVDARPLLSEIVPGVRALPLPAEQAFGFEAIVGDGNHLLLRFTPAKGYYLYRDRTSLALEGDKTVHTGVAYWPQG
SKYHDEHFGDVVVYFNQIEVMLPLQRDYSGPIANATLVATFQGCQIDGICYPPMTRRVRLSLPSGKVSSPNRANAIPLMG
NHASLQNPLRLPGSNVPPATASQSAVSVDSALENHPSYSASKFFMALSLALVGGLLLNLLPCVLPVLSLKVLALAKSGES
RACARRHAIWYTAGVLLSFGVIGGIAIMAKILWGFQLQQPGFVGVLVYLMFAVGLSLSGVFTMSSTKFGAIGQSLMARSG
SLGDFFAGVLACVVSSACIGPFMGPALVYAFTAPPLLAMLVFLTLGFGLALPFLLLGFVPSLTRRLPTPGPWMQTLKYVL
ALPMYLTAIWLLWVLGKQRGVDAQSLLLVGLVMLAMGLCWFERSRWNADRWGLVLSSVLLLLTLLPLWGVTQLKIPHSIP
QNVSSDEVAYSPLLLDRLRADNRVVFVNVTADWCVTCKANERNVLSSDAFHDVMHRIDAVYMKGDWTNGDAQISAFLSQH
QAVGVPLYVVYGPGAPPNILPNVLTKDVVEDALLRAAR
>Mature_757_residues
TFLHRLATLCVLALISFPVVAVSETDLLPVEKAFVVGVKALDRHHVLVHWKIAEGYYLYRHRIAVRVLNDGVLKSDSKLN
LPNGYRKNDSYLGDVEIYRGSLTAVRSVLPVKGVHKLTLQVNYQGCADAGVCYPPQVRTLHVALPTDGNDLDRGAVVDRQ
DRGSAVDARPLLSEIVPGVRALPLPAEQAFGFEAIVGDGNHLLLRFTPAKGYYLYRDRTSLALEGDKTVHTGVAYWPQGS
KYHDEHFGDVVVYFNQIEVMLPLQRDYSGPIANATLVATFQGCQIDGICYPPMTRRVRLSLPSGKVSSPNRANAIPLMGN
HASLQNPLRLPGSNVPPATASQSAVSVDSALENHPSYSASKFFMALSLALVGGLLLNLLPCVLPVLSLKVLALAKSGESR
ACARRHAIWYTAGVLLSFGVIGGIAIMAKILWGFQLQQPGFVGVLVYLMFAVGLSLSGVFTMSSTKFGAIGQSLMARSGS
LGDFFAGVLACVVSSACIGPFMGPALVYAFTAPPLLAMLVFLTLGFGLALPFLLLGFVPSLTRRLPTPGPWMQTLKYVLA
LPMYLTAIWLLWVLGKQRGVDAQSLLLVGLVMLAMGLCWFERSRWNADRWGLVLSSVLLLLTLLPLWGVTQLKIPHSIPQ
NVSSDEVAYSPLLLDRLRADNRVVFVNVTADWCVTCKANERNVLSSDAFHDVMHRIDAVYMKGDWTNGDAQISAFLSQHQ
AVGVPLYVVYGPGAPPNILPNVLTKDVVEDALLRAAR

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=578, Percent_Identity=26.2975778546713, Blast_Score=128, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 82388; Mature: 82257

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLHRLATLCVLALISFPVVAVSETDLLPVEKAFVVGVKALDRHHVLVHWKIAEGYYLY
CHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCEEEE
RHRIAVRVLNDGVLKSDSKLNLPNGYRKNDSYLGDVEIYRGSLTAVRSVLPVKGVHKLTL
EHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCEEEEE
QVNYQGCADAGVCYPPQVRTLHVALPTDGNDLDRGAVVDRQDRGSAVDARPLLSEIVPGV
EEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
RALPLPAEQAFGFEAIVGDGNHLLLRFTPAKGYYLYRDRTSLALEGDKTVHTGVAYWPQG
EECCCCHHHHCCCEEEECCCCEEEEEEECCCCEEEEECCCEEEECCCCEEECCEEECCCC
SKYHDEHFGDVVVYFNQIEVMLPLQRDYSGPIANATLVATFQGCQIDGICYPPMTRRVRL
CCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCEEEEEECCCEECCEECCCCCCEEEE
SLPSGKVSSPNRANAIPLMGNHASLQNPLRLPGSNVPPATASQSAVSVDSALENHPSYSA
ECCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCH
SKFFMALSLALVGGLLLNLLPCVLPVLSLKVLALAKSGESRACARRHAIWYTAGVLLSFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VIGGIAIMAKILWGFQLQQPGFVGVLVYLMFAVGLSLSGVFTMSSTKFGAIGQSLMARSG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCC
SLGDFFAGVLACVVSSACIGPFMGPALVYAFTAPPLLAMLVFLTLGFGLALPFLLLGFVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLTRRLPTPGPWMQTLKYVLALPMYLTAIWLLWVLGKQRGVDAQSLLLVGLVMLAMGLCW
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FERSRWNADRWGLVLSSVLLLLTLLPLWGVTQLKIPHSIPQNVSSDEVAYSPLLLDRLRA
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
DNRVVFVNVTADWCVTCKANERNVLSSDAFHDVMHRIDAVYMKGDWTNGDAQISAFLSQH
CCEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHC
QAVGVPLYVVYGPGAPPNILPNVLTKDVVEDALLRAAR
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFLHRLATLCVLALISFPVVAVSETDLLPVEKAFVVGVKALDRHHVLVHWKIAEGYYLY
HHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCEEEE
RHRIAVRVLNDGVLKSDSKLNLPNGYRKNDSYLGDVEIYRGSLTAVRSVLPVKGVHKLTL
EHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCEEEEE
QVNYQGCADAGVCYPPQVRTLHVALPTDGNDLDRGAVVDRQDRGSAVDARPLLSEIVPGV
EEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
RALPLPAEQAFGFEAIVGDGNHLLLRFTPAKGYYLYRDRTSLALEGDKTVHTGVAYWPQG
EECCCCHHHHCCCEEEECCCCEEEEEEECCCCEEEEECCCEEEECCCCEEECCEEECCCC
SKYHDEHFGDVVVYFNQIEVMLPLQRDYSGPIANATLVATFQGCQIDGICYPPMTRRVRL
CCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCEEEEEECCCEECCEECCCCCCEEEE
SLPSGKVSSPNRANAIPLMGNHASLQNPLRLPGSNVPPATASQSAVSVDSALENHPSYSA
ECCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCH
SKFFMALSLALVGGLLLNLLPCVLPVLSLKVLALAKSGESRACARRHAIWYTAGVLLSFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VIGGIAIMAKILWGFQLQQPGFVGVLVYLMFAVGLSLSGVFTMSSTKFGAIGQSLMARSG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCC
SLGDFFAGVLACVVSSACIGPFMGPALVYAFTAPPLLAMLVFLTLGFGLALPFLLLGFVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLTRRLPTPGPWMQTLKYVLALPMYLTAIWLLWVLGKQRGVDAQSLLLVGLVMLAMGLCW
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FERSRWNADRWGLVLSSVLLLLTLLPLWGVTQLKIPHSIPQNVSSDEVAYSPLLLDRLRA
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
DNRVVFVNVTADWCVTCKANERNVLSSDAFHDVMHRIDAVYMKGDWTNGDAQISAFLSQH
CCEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHC
QAVGVPLYVVYGPGAPPNILPNVLTKDVVEDALLRAAR
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA