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The map label for this gene is trpE2 [H]

Identifier: 182682107

GI number: 182682107

Start: 1756099

End: 1757457

Strand: Reverse

Name: trpE2 [H]

Synonym: XfasM23_1585

Alternate gene names: 182682107

Gene position: 1757457-1756099 (Counterclockwise)

Preceding gene: 182682108

Following gene: 182682106

Centisome position: 69.31

GC content: 54.45

Gene sequence:

>1359_bases
ATGACACTCATTCGATTTCTGCGTACGGATCCGGATTTATTGTCCATGCACCGGTTGGCACCGGAGCGTTATCCGGCGCT
TTTTGAATCTACTGCTTCTGGTACTCAGCAGAGTCGTTGGGATGTGTTGTTGCATACAGATGGTCGTTTCTTCCGTTTGG
ATTCCGATGGTGTAACACGCGATGCTCAGGGCAGGGCGCTGTCCGGAGACTTTTTGCAGGTATTGGATGCAGTGTGGAGC
ACTGAGTACGTGCTGCGTGATACGTGTGAGGATGCTCCTCCATTCCGTGGCGGTTGGGCTTTACTTCTTGACTATGAACT
GGCTGGGCAGGTTGAGCCAGTGTTGAAATTGCCAGTGCGTACTGATGGTTTGCCTATGGCGTTAGCATTGCGTTGTCCGG
CAGCGGTATTACGTGACCGCCACAGTGGTGTTTTTTTGATTGTCGCTGAGCTGGGAAATGAGCATTTACTGGACGTGATT
GAGGCGGATTTAGCTGCTGTTGCCTTGTTGCCGCCATTGCCGGTTTGGCGATCTCCAGTGGCCGTGACTGAGGATGAGCC
GTCGCAGTTTATTGCCAATGCAGAGCGTGTGCTGGATTACCTTCGTGAGGGAGACGTGTTCCAGGCAAATATCTCACGCC
TTTGGGAAGCTCGCTTTGCCACTGCACTTGATCCAGCAGCGTTGTACATGCGTTTGCGTGTAGCCAATCCTGCGCCTTTC
TCGGGATTGTTTGTGGCTCATGGCCGAGCTGTGGTGAGCTCCTCACCAGAGCGGTTGATTTCGGTGCAAGGAGGGCGCAT
TCAGACGCGTCCGATTGCTGGTACCCGGCCACGTTTTGTCGGTGAAGATGACGCAGCACGCATCCGCGAACTGGTGAATC
ACCCTAAGGAGCGTGCTGAGCATGTGATGTTGATTGACTTAGAGCGTAACGATTTAGGGAGAGTGTGTGTGCCTGGGACC
GTTGAGGTCGATGAGTTGATGACGGTGGAAAGCTATGCGCATGTCCATCATATCGTCAGTAATGTGCGTGGCTGGTTGCC
TACGGGCAGGACCCCAGGGGAGATCATTCGCGCCGTGTTTCCGGGGGGGACAATCACTGGTTGTCCGAAGGTGCGTTGCA
TGCAGATCATTGCCCAGCTCGAGCAGGTGGCACGCGGTGCCTACACTGGTGCCTTTGGATGGCTCAATTGTGATGGTGAT
TTGGACCTGAACATTTTAATCCGCACCGCTGAGATTGACGGTGTGACTGTACGTTTCCGTAACGGTGCCGGCATCGTGAT
CAATTCACTGCCTGAGCGTGAGCTGGATGAGACCCGTGCCAAGGCGACTGGCGTACTGCGCGCCCTGCATGTCATCTGA

Upstream 100 bases:

>100_bases
TTTTCCGATGGCATGGCGCCTCGCTATGTTTCTATGTAGGCGGAGAGACTCAACGTGCCTTCCCTATGCTTCGCAGCTGA
TCTGAATCCAGTCTAGACTA

Downstream 100 bases:

>100_bases
ACGTTAGTTTTCGGTGATGCTGATACGCGCGTTATGCTGTCTGGCCTTGAAGGCTTGACGAGGTGGACTTGGTGGGACGC
AAACGCGGATGTCTAGTCGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTLIRFLRTDPDLLSMHRLAPERYPALFESTASGTQQSRWDVLLHTDGRFFRLDSDGVTRDAQGRALSGDFLQVLDAVWS
TEYVLRDTCEDAPPFRGGWALLLDYELAGQVEPVLKLPVRTDGLPMALALRCPAAVLRDRHSGVFLIVAELGNEHLLDVI
EADLAAVALLPPLPVWRSPVAVTEDEPSQFIANAERVLDYLREGDVFQANISRLWEARFATALDPAALYMRLRVANPAPF
SGLFVAHGRAVVSSSPERLISVQGGRIQTRPIAGTRPRFVGEDDAARIRELVNHPKERAEHVMLIDLERNDLGRVCVPGT
VEVDELMTVESYAHVHHIVSNVRGWLPTGRTPGEIIRAVFPGGTITGCPKVRCMQIIAQLEQVARGAYTGAFGWLNCDGD
LDLNILIRTAEIDGVTVRFRNGAGIVINSLPERELDETRAKATGVLRALHVI

Sequences:

>Translated_452_residues
MTLIRFLRTDPDLLSMHRLAPERYPALFESTASGTQQSRWDVLLHTDGRFFRLDSDGVTRDAQGRALSGDFLQVLDAVWS
TEYVLRDTCEDAPPFRGGWALLLDYELAGQVEPVLKLPVRTDGLPMALALRCPAAVLRDRHSGVFLIVAELGNEHLLDVI
EADLAAVALLPPLPVWRSPVAVTEDEPSQFIANAERVLDYLREGDVFQANISRLWEARFATALDPAALYMRLRVANPAPF
SGLFVAHGRAVVSSSPERLISVQGGRIQTRPIAGTRPRFVGEDDAARIRELVNHPKERAEHVMLIDLERNDLGRVCVPGT
VEVDELMTVESYAHVHHIVSNVRGWLPTGRTPGEIIRAVFPGGTITGCPKVRCMQIIAQLEQVARGAYTGAFGWLNCDGD
LDLNILIRTAEIDGVTVRFRNGAGIVINSLPERELDETRAKATGVLRALHVI
>Mature_451_residues
TLIRFLRTDPDLLSMHRLAPERYPALFESTASGTQQSRWDVLLHTDGRFFRLDSDGVTRDAQGRALSGDFLQVLDAVWST
EYVLRDTCEDAPPFRGGWALLLDYELAGQVEPVLKLPVRTDGLPMALALRCPAAVLRDRHSGVFLIVAELGNEHLLDVIE
ADLAAVALLPPLPVWRSPVAVTEDEPSQFIANAERVLDYLREGDVFQANISRLWEARFATALDPAALYMRLRVANPAPFS
GLFVAHGRAVVSSSPERLISVQGGRIQTRPIAGTRPRFVGEDDAARIRELVNHPKERAEHVMLIDLERNDLGRVCVPGTV
EVDELMTVESYAHVHHIVSNVRGWLPTGRTPGEIIRAVFPGGTITGCPKVRCMQIIAQLEQVARGAYTGAFGWLNCDGDL
DLNILIRTAEIDGVTVRFRNGAGIVINSLPERELDETRAKATGVLRALHVI

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=459, Percent_Identity=32.244008714597, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1787518, Length=291, Percent_Identity=38.4879725085911, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1786809, Length=246, Percent_Identity=27.6422764227642, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082077, Length=299, Percent_Identity=24.0802675585284, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320935, Length=439, Percent_Identity=30.751708428246, Blast_Score=168, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324361, Length=281, Percent_Identity=27.7580071174377, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR010118 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 49916; Mature: 49785

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLIRFLRTDPDLLSMHRLAPERYPALFESTASGTQQSRWDVLLHTDGRFFRLDSDGVTR
CCEEEECCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEECCCCCCC
DAQGRALSGDFLQVLDAVWSTEYVLRDTCEDAPPFRGGWALLLDYELAGQVEPVLKLPVR
CCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEEECCCC
TDGLPMALALRCPAAVLRDRHSGVFLIVAELGNEHLLDVIEADLAAVALLPPLPVWRSPV
CCCCCEEEEHHCCHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCE
AVTEDEPSQFIANAERVLDYLREGDVFQANISRLWEARFATALDPAALYMRLRVANPAPF
EECCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCC
SGLFVAHGRAVVSSSPERLISVQGGRIQTRPIAGTRPRFVGEDDAARIRELVNHPKERAE
CCEEEECCCEEECCCCCCEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHCC
HVMLIDLERNDLGRVCVPGTVEVDELMTVESYAHVHHIVSNVRGWLPTGRTPGEIIRAVF
EEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
PGGTITGCPKVRCMQIIAQLEQVARGAYTGAFGWLNCDGDLDLNILIRTAEIDGVTVRFR
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEEEECCCEEEEEE
NGAGIVINSLPERELDETRAKATGVLRALHVI
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLIRFLRTDPDLLSMHRLAPERYPALFESTASGTQQSRWDVLLHTDGRFFRLDSDGVTR
CEEEECCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEECCCCCCC
DAQGRALSGDFLQVLDAVWSTEYVLRDTCEDAPPFRGGWALLLDYELAGQVEPVLKLPVR
CCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEEECCCC
TDGLPMALALRCPAAVLRDRHSGVFLIVAELGNEHLLDVIEADLAAVALLPPLPVWRSPV
CCCCCEEEEHHCCHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCE
AVTEDEPSQFIANAERVLDYLREGDVFQANISRLWEARFATALDPAALYMRLRVANPAPF
EECCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCC
SGLFVAHGRAVVSSSPERLISVQGGRIQTRPIAGTRPRFVGEDDAARIRELVNHPKERAE
CCEEEECCCEEECCCCCCEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHCC
HVMLIDLERNDLGRVCVPGTVEVDELMTVESYAHVHHIVSNVRGWLPTGRTPGEIIRAVF
EEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
PGGTITGCPKVRCMQIIAQLEQVARGAYTGAFGWLNCDGDLDLNILIRTAEIDGVTVRFR
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEEEECCCEEEEEE
NGAGIVINSLPERELDETRAKATGVLRALHVI
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]