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The map label for this gene is mtaD [H]

Identifier: 182682097

GI number: 182682097

Start: 1747258

End: 1748601

Strand: Reverse

Name: mtaD [H]

Synonym: XfasM23_1575

Alternate gene names: 182682097

Gene position: 1748601-1747258 (Counterclockwise)

Preceding gene: 182682098

Following gene: 182682096

Centisome position: 68.96

GC content: 58.04

Gene sequence:

>1344_bases
ATGACCAATGAATCTCTCCCTGCTGAACCCTGCGATGTGCTGATCGAGGCTGGCTACGTTGTCCCCATCCAACCACATGG
CATCGTGCTAGAACAACATGCCGTTGCGGTCCGTGAGAGTGTCATCGTTGGCCTACTTCCAATTGCCGAGGCCCGCCTGC
GCTTTGCCCCCTCGCTCACGGTCAGCCGCCCTCAAGCCGCCTTATTACCCGGATTGGTCAACGCCCATACCCACAACCCC
ATGACCCTACTACGTGGCATGGCCGATGACCTGCCACTCATGACATGGTTGCAACAACACATCTGGCCCGTGGAGACCGC
CGTGATCGGCCCGGAATTTGTGGGCGACGGCACCGCACTGGCCATCGCCGAGATGCTGCGTGGTGGCACCACCTGCGCCA
ACGAGAACTATTTTTTCCCTGATGTCCAAGCCGCCGTTTACAAACAGCACGGTTTCCGCGCCCTGGTCGGTGCGATCATC
ATTGATTTTCCGACCGCCTGGGCCAACAGCGATGATGAGTACTTTGCCCGTGCCATTGAATTGCACGACCAATGGCGCGG
CGATCCCTTAATCGGTACCGCCTTTGCGCCACATGCCCCCTATACAGTGAGCGATGCGAACTTCGAGCGCATCCGCGTCC
TTGCCGATCAACTGGATGTTTTGGTGCATCTGCATACCCACGAAACCGCCCAGGAAATTGCTGACTCCATCAAACACCAT
GGCCAGCGTCCGTTGGCGCGATTGGACCGGCTTGATTTGGTCAATGACCGCCTGATTGCGGTACATATGACGCAATTAAC
AGAAGCCGAGATCCAATTGTGCGCCACACGTGGAGTTAGCGTAGTGCATTGCCCAGAATCCAACCTCAAACTGGCTTCCG
GTTTTTGCCCCGCTTTCGCACTGCACCGCGCTGGTGTGAACCTCGCCATCGGTACCGATGGCTGTGCAAGCAACAACGAC
CTAGACATGTTTAGTGAACATCGCATCGCAGCCATGCTGGCGAAAGCTGTGGCCAACGACCCTACCGCCTTGGACGCAGC
GACCACCTTGCGTGCGGCGACCCTGGGCGGTGCCCGCGCACTCGGTTTCGGCCATCTGATCGGTTCCATTGAAATCGGCA
AGCAAGCCGACCTGATCTGCGTGGACTTGAGCGCGCTCGAAACACAACCCTTGTACCACGTACTCTCGCAACTGGTTTAC
GCTGCAGGGCGTCAGCACGTCACGGATGTGTGGATTGCCGGCCAGCCAAAATTGATCCAGCGTGAGCTCATCGGCATTGA
TACCGCAGCACTGCTGACTAAAGCGCGTCAGTGGCGCGAGCGCATCCGCGCCATCCGTATTTGA

Upstream 100 bases:

>100_bases
TTGAGAACCCGATGCCAGCCAACATAGCAACCACACTGGCTGGCCTTTGCTTTACAGACAGGGCCAGATCCTCCTACATC
ACCTTCTGGCCCCACTTGTC

Downstream 100 bases:

>100_bases
ATCCTGCGCACCGCTTCAAGGAGATTCGCCATGCCCTCCTCATATGACCGTGTTTCCAAGAATTACCGCCAAAGTGAACT
GGATAAATTCGCATCCTTCA

Product: N-ethylammeline chlorohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTNESLPAEPCDVLIEAGYVVPIQPHGIVLEQHAVAVRESVIVGLLPIAEARLRFAPSLTVSRPQAALLPGLVNAHTHNP
MTLLRGMADDLPLMTWLQQHIWPVETAVIGPEFVGDGTALAIAEMLRGGTTCANENYFFPDVQAAVYKQHGFRALVGAII
IDFPTAWANSDDEYFARAIELHDQWRGDPLIGTAFAPHAPYTVSDANFERIRVLADQLDVLVHLHTHETAQEIADSIKHH
GQRPLARLDRLDLVNDRLIAVHMTQLTEAEIQLCATRGVSVVHCPESNLKLASGFCPAFALHRAGVNLAIGTDGCASNND
LDMFSEHRIAAMLAKAVANDPTALDAATTLRAATLGGARALGFGHLIGSIEIGKQADLICVDLSALETQPLYHVLSQLVY
AAGRQHVTDVWIAGQPKLIQRELIGIDTAALLTKARQWRERIRAIRI

Sequences:

>Translated_447_residues
MTNESLPAEPCDVLIEAGYVVPIQPHGIVLEQHAVAVRESVIVGLLPIAEARLRFAPSLTVSRPQAALLPGLVNAHTHNP
MTLLRGMADDLPLMTWLQQHIWPVETAVIGPEFVGDGTALAIAEMLRGGTTCANENYFFPDVQAAVYKQHGFRALVGAII
IDFPTAWANSDDEYFARAIELHDQWRGDPLIGTAFAPHAPYTVSDANFERIRVLADQLDVLVHLHTHETAQEIADSIKHH
GQRPLARLDRLDLVNDRLIAVHMTQLTEAEIQLCATRGVSVVHCPESNLKLASGFCPAFALHRAGVNLAIGTDGCASNND
LDMFSEHRIAAMLAKAVANDPTALDAATTLRAATLGGARALGFGHLIGSIEIGKQADLICVDLSALETQPLYHVLSQLVY
AAGRQHVTDVWIAGQPKLIQRELIGIDTAALLTKARQWRERIRAIRI
>Mature_446_residues
TNESLPAEPCDVLIEAGYVVPIQPHGIVLEQHAVAVRESVIVGLLPIAEARLRFAPSLTVSRPQAALLPGLVNAHTHNPM
TLLRGMADDLPLMTWLQQHIWPVETAVIGPEFVGDGTALAIAEMLRGGTTCANENYFFPDVQAAVYKQHGFRALVGAIII
DFPTAWANSDDEYFARAIELHDQWRGDPLIGTAFAPHAPYTVSDANFERIRVLADQLDVLVHLHTHETAQEIADSIKHHG
QRPLARLDRLDLVNDRLIAVHMTQLTEAEIQLCATRGVSVVHCPESNLKLASGFCPAFALHRAGVNLAIGTDGCASNNDL
DMFSEHRIAAMLAKAVANDPTALDAATTLRAATLGGARALGFGHLIGSIEIGKQADLICVDLSALETQPLYHVLSQLVYA
AGRQHVTDVWIAGQPKLIQRELIGIDTAALLTKARQWRERIRAIRI

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=443, Percent_Identity=23.4762979683973, Blast_Score=123, Evalue=4e-28,
Organism=Escherichia coli, GI1789249, Length=333, Percent_Identity=26.4264264264264, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87082177, Length=445, Percent_Identity=24.7191011235955, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17540282, Length=381, Percent_Identity=24.1469816272966, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319963, Length=339, Percent_Identity=24.4837758112094, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24643849, Length=382, Percent_Identity=26.4397905759162, Blast_Score=132, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 48622; Mature: 48491

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNESLPAEPCDVLIEAGYVVPIQPHGIVLEQHAVAVRESVIVGLLPIAEARLRFAPSLT
CCCCCCCCCHHHHHEECCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VSRPQAALLPGLVNAHTHNPMTLLRGMADDLPLMTWLQQHIWPVETAVIGPEFVGDGTAL
CCCCHHHHCCCHHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHEEECCHHCCCCHHH
AIAEMLRGGTTCANENYFFPDVQAAVYKQHGFRALVGAIIIDFPTAWANSDDEYFARAIE
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LHDQWRGDPLIGTAFAPHAPYTVSDANFERIRVLADQLDVLVHLHTHETAQEIADSIKHH
HHHHCCCCCCEECCCCCCCCEEECCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHC
GQRPLARLDRLDLVNDRLIAVHMTQLTEAEIQLCATRGVSVVHCPESNLKLASGFCPAFA
CCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCEEEECCCCCCEECCCCCHHHH
LHRAGVNLAIGTDGCASNNDLDMFSEHRIAAMLAKAVANDPTALDAATTLRAATLGGARA
HHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHH
LGFGHLIGSIEIGKQADLICVDLSALETQPLYHVLSQLVYAAGRQHVTDVWIAGQPKLIQ
HHHHHHHCCEEECCCCCEEEEEHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHH
RELIGIDTAALLTKARQWRERIRAIRI
HHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNESLPAEPCDVLIEAGYVVPIQPHGIVLEQHAVAVRESVIVGLLPIAEARLRFAPSLT
CCCCCCCCHHHHHEECCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VSRPQAALLPGLVNAHTHNPMTLLRGMADDLPLMTWLQQHIWPVETAVIGPEFVGDGTAL
CCCCHHHHCCCHHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHEEECCHHCCCCHHH
AIAEMLRGGTTCANENYFFPDVQAAVYKQHGFRALVGAIIIDFPTAWANSDDEYFARAIE
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LHDQWRGDPLIGTAFAPHAPYTVSDANFERIRVLADQLDVLVHLHTHETAQEIADSIKHH
HHHHCCCCCCEECCCCCCCCEEECCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHC
GQRPLARLDRLDLVNDRLIAVHMTQLTEAEIQLCATRGVSVVHCPESNLKLASGFCPAFA
CCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCEEEECCCCCCEECCCCCHHHH
LHRAGVNLAIGTDGCASNNDLDMFSEHRIAAMLAKAVANDPTALDAATTLRAATLGGARA
HHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHH
LGFGHLIGSIEIGKQADLICVDLSALETQPLYHVLSQLVYAAGRQHVTDVWIAGQPKLIQ
HHHHHHHCCEEECCCCCEEEEEHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHH
RELIGIDTAALLTKARQWRERIRAIRI
HHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA