Click here to switch to the map view.

The map label for this gene is efp

Identifier: 182682098

GI number: 182682098

Start: 1748739

End: 1749305

Strand: Reverse

Name: efp

Synonym: XfasM23_1576

Alternate gene names: 182682098

Gene position: 1749305-1748739 (Counterclockwise)

Preceding gene: 182682100

Following gene: 182682097

Centisome position: 68.99

GC content: 51.15

Gene sequence:

>567_bases
ATGGCCAGTTACGGCATGAACGATGTAAAAAACGGCATGAAAATTCTGGTCAATGCCGAACCCGCAGTCATTACGGACAC
TGAATATGTCAAGCCTGGTAAGGGCCAAGCCTTTACCCGCGTCAAATACCGTTTGATCAAATCTGGCCGGGTGCAGGAAG
TCACCATGAAATCCACCGATACGCTTGAAGCAGCCGACGTGGTCGATACAGATATGCAGTATTTGTACAGCGATGGCGAA
TACTGGCACTTCATGCAACAAGAAACCTTTGAACAAGTTCAAGCCGACAAAAACGGAATGGGTGGCGCCGAAAAATGGCT
TAAAGGTGAAGAACAGTGTGTGGTCACACTCTGGAACGGTGTGCCGATCGGAGTGCAGCCACCGAACTTCGTCGAACTGA
AAATCACCGAAACCGATCCGGGCTTACGCGGTGACACCTCTGGCGGCGGCGGCAAGCCCGCTACCTTGGAAACCGGTGCT
GTCGTGCGTGTCCCGTTATTTGTGAATCAAGATGAAGTCATCAAAGTGGATACCCGCTCTGGCGAGTACGTCTCACGTGT
CAAATAA

Upstream 100 bases:

>100_bases
TGCGTTGAGGAAAAACCCACCATGTTCGGTGGGCTGCCTCATTGTATCCGCTGCCCCCTCCTATCGCGGCGGTTTTTTTG
TTTAATTGAGGAACTTCAGC

Downstream 100 bases:

>100_bases
CACGGTTTCTTCCACTGATTGCGTATGCAAGCCACTATTGAGAACCCGATGCCAGCCAACATAGCAACCACACTGGCTGG
CCTTTGCTTTACAGACAGGG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MASYGMNDVKNGMKILVNAEPAVITDTEYVKPGKGQAFTRVKYRLIKSGRVQEVTMKSTDTLEAADVVDTDMQYLYSDGE
YWHFMQQETFEQVQADKNGMGGAEKWLKGEEQCVVTLWNGVPIGVQPPNFVELKITETDPGLRGDTSGGGGKPATLETGA
VVRVPLFVNQDEVIKVDTRSGEYVSRVK

Sequences:

>Translated_188_residues
MASYGMNDVKNGMKILVNAEPAVITDTEYVKPGKGQAFTRVKYRLIKSGRVQEVTMKSTDTLEAADVVDTDMQYLYSDGE
YWHFMQQETFEQVQADKNGMGGAEKWLKGEEQCVVTLWNGVPIGVQPPNFVELKITETDPGLRGDTSGGGGKPATLETGA
VVRVPLFVNQDEVIKVDTRSGEYVSRVK
>Mature_187_residues
ASYGMNDVKNGMKILVNAEPAVITDTEYVKPGKGQAFTRVKYRLIKSGRVQEVTMKSTDTLEAADVVDTDMQYLYSDGEY
WHFMQQETFEQVQADKNGMGGAEKWLKGEEQCVVTLWNGVPIGVQPPNFVELKITETDPGLRGDTSGGGGKPATLETGAV
VRVPLFVNQDEVIKVDTRSGEYVSRVK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=63.2978723404255, Blast_Score=254, Evalue=2e-69,
Organism=Escherichia coli, GI87082061, Length=187, Percent_Identity=27.807486631016, Blast_Score=77, Evalue=8e-16,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_XYLF2 (B2I707)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830258.1
- ProteinModelPortal:   B2I707
- SMR:   B2I707
- GeneID:   6202671
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1576
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20745; Mature: 20614

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASYGMNDVKNGMKILVNAEPAVITDTEYVKPGKGQAFTRVKYRLIKSGRVQEVTMKSTD
CCCCCCHHHCCCEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCC
TLEAADVVDTDMQYLYSDGEYWHFMQQETFEQVQADKNGMGGAEKWLKGEEQCVVTLWNG
CCCHHHHHHHCHHEEECCCCEEEHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEECC
VPIGVQPPNFVELKITETDPGLRGDTSGGGGKPATLETGAVVRVPLFVNQDEVIKVDTRS
EECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCEEEEECCC
GEYVSRVK
CCEEECCC
>Mature Secondary Structure 
ASYGMNDVKNGMKILVNAEPAVITDTEYVKPGKGQAFTRVKYRLIKSGRVQEVTMKSTD
CCCCCHHHCCCEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCC
TLEAADVVDTDMQYLYSDGEYWHFMQQETFEQVQADKNGMGGAEKWLKGEEQCVVTLWNG
CCCHHHHHHHCHHEEECCCCEEEHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEECC
VPIGVQPPNFVELKITETDPGLRGDTSGGGGKPATLETGAVVRVPLFVNQDEVIKVDTRS
EECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCEEEEECCC
GEYVSRVK
CCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA