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The map label for this gene is lacF [H]

Identifier: 182682071

GI number: 182682071

Start: 1722677

End: 1723558

Strand: Reverse

Name: lacF [H]

Synonym: XfasM23_1549

Alternate gene names: 182682071

Gene position: 1723558-1722677 (Counterclockwise)

Preceding gene: 182682072

Following gene: 182682070

Centisome position: 67.97

GC content: 50.91

Gene sequence:

>882_bases
ATGAGGCGGGCTTCTTTGGTGGGTTGGGTGTTTGCTGGTCCTGCGGTGTTGGTTATCGGGATGTTCTTCGGTGTGCCGGT
GTTGATGGCGTTGGCGCTCAGTTTGACCGATTTCGATTTGTATGCTCTGGGCAATCCGATGTATCTGCGTTTTGTTGGAT
TGGATAATTATCTGGAGTTGTTGCACACCCCGTTGTTCTGGAAGTCGCTGTGGAATACGACCTATTTTGTGCTGCTGGGG
ATGCCGATGTCGATTATGGTGTCTCTGGGAGCTGCGTTGCTGCTGAATTCAAGAGCGGCGCGTTTTAAGGGATTGTTTCG
CACCGTGTTGTTTGCTCCGGTGGTGACGACGCTGGTAGCTGTCGCGCTGATTTGGCGTTATCTGTTTCACCTGAAGTATG
GGGTGGTGAATTGGCTGCTGAATTGTGTTGGTATTCATCCAATTGATTGGTTGGGTGATCCGCGTTTGGCGATGCCGATG
ATCATGTTGTTCGCGGTGTGGAAGAACTTTGGCTACAACATGGTGATTTTTCTGGCCGGGTTGCAGGCGATTCCACAGGA
TCTGTACGAGGCTGCGCGCATTGATGGCGCGTCCAAATGGCAGCAATTCTTGCATATCACGTTTCCGATGCTGGGGCCTG
TGCTGATGGTGGTTGGGATTATCACGGTATCCGGCTATTTCCAGTTGTTTGCAGAGCCTTATGTGATGACCCGAGGGGAT
CCTCTACAGAGTACGGTCAGTGTGCTGTATTTCATGTTTGAGGAGGGTTTTAAGTGGTGGAATCTGGGACGTGCTTCTGC
TGTCGCGTTTCTGTTGTTTTTGGTTGTTCTTGGGGTGACGACGTTGATGCTGTGTGCTGGACGTAGGAAAGATTTGGTAT
GA

Upstream 100 bases:

>100_bases
CGGTAGAGCAACTTGATCAGCGGGTCGATAAGATTCTTGCTAAGCGTCGTTGGATCCAGCAACAGGTCGGTAAGGGGCCG
CATGCTGAGGGAGTGCATCC

Downstream 100 bases:

>100_bases
GTCGTGAGGTCGGGCGCACGAAGTGGAATATTGTGTTTGTCAATGGGTGCTTATTTATGTTTGCGTTGGTGAGTCTGGCG
CCCTTGCTTTGGATGGTGTC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MRRASLVGWVFAGPAVLVIGMFFGVPVLMALALSLTDFDLYALGNPMYLRFVGLDNYLELLHTPLFWKSLWNTTYFVLLG
MPMSIMVSLGAALLLNSRAARFKGLFRTVLFAPVVTTLVAVALIWRYLFHLKYGVVNWLLNCVGIHPIDWLGDPRLAMPM
IMLFAVWKNFGYNMVIFLAGLQAIPQDLYEAARIDGASKWQQFLHITFPMLGPVLMVVGIITVSGYFQLFAEPYVMTRGD
PLQSTVSVLYFMFEEGFKWWNLGRASAVAFLLFLVVLGVTTLMLCAGRRKDLV

Sequences:

>Translated_293_residues
MRRASLVGWVFAGPAVLVIGMFFGVPVLMALALSLTDFDLYALGNPMYLRFVGLDNYLELLHTPLFWKSLWNTTYFVLLG
MPMSIMVSLGAALLLNSRAARFKGLFRTVLFAPVVTTLVAVALIWRYLFHLKYGVVNWLLNCVGIHPIDWLGDPRLAMPM
IMLFAVWKNFGYNMVIFLAGLQAIPQDLYEAARIDGASKWQQFLHITFPMLGPVLMVVGIITVSGYFQLFAEPYVMTRGD
PLQSTVSVLYFMFEEGFKWWNLGRASAVAFLLFLVVLGVTTLMLCAGRRKDLV
>Mature_293_residues
MRRASLVGWVFAGPAVLVIGMFFGVPVLMALALSLTDFDLYALGNPMYLRFVGLDNYLELLHTPLFWKSLWNTTYFVLLG
MPMSIMVSLGAALLLNSRAARFKGLFRTVLFAPVVTTLVAVALIWRYLFHLKYGVVNWLLNCVGIHPIDWLGDPRLAMPM
IMLFAVWKNFGYNMVIFLAGLQAIPQDLYEAARIDGASKWQQFLHITFPMLGPVLMVVGIITVSGYFQLFAEPYVMTRGD
PLQSTVSVLYFMFEEGFKWWNLGRASAVAFLLFLVVLGVTTLMLCAGRRKDLV

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787570, Length=247, Percent_Identity=33.1983805668016, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1789861, Length=295, Percent_Identity=29.8305084745763, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1790465, Length=263, Percent_Identity=30.0380228136882, Blast_Score=94, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33016; Mature: 33016

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRRASLVGWVFAGPAVLVIGMFFGVPVLMALALSLTDFDLYALGNPMYLRFVGLDNYLEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEECHHHHHHH
LHTPLFWKSLWNTTYFVLLGMPMSIMVSLGAALLLNSRAARFKGLFRTVLFAPVVTTLVA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALIWRYLFHLKYGVVNWLLNCVGIHPIDWLGDPRLAMPMIMLFAVWKNFGYNMVIFLAG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
LQAIPQDLYEAARIDGASKWQQFLHITFPMLGPVLMVVGIITVSGYFQLFAEPYVMTRGD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
PLQSTVSVLYFMFEEGFKWWNLGRASAVAFLLFLVVLGVTTLMLCAGRRKDLV
CHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]