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The map label for this gene is nagZ

Identifier: 182681993

GI number: 182681993

Start: 1619698

End: 1620705

Strand: Reverse

Name: nagZ

Synonym: XfasM23_1468

Alternate gene names: 182681993

Gene position: 1620705-1619698 (Counterclockwise)

Preceding gene: 182681994

Following gene: 182681992

Centisome position: 63.92

GC content: 54.17

Gene sequence:

>1008_bases
ATGTTACTGATTGGTGTGGCGGGTACGACGCTCAGTGCTCAGGAGGTGGATTGGTTGCAGGACGATGCGGTGGCCGGTGT
TGTGTTGTTTAAGCGTAATTTTGCTTCACGTGCGCAAATTGTCGAATTATCGGCTGCGCTGCGTGAAGCTGCACCGCGGC
CGCTGTTGTTGGCGGTTGATCAGGAGGGTGGGCGTGTGCAGCGCTTCCATGAGGGCTATAGTGCGTTACCACCATTACAG
GGGATTGGTGCATTGTATGTACGCGATCCGGAGGCGGCATTGGAGTTGGCGTTCGAGCATGCTTGGTTGATGGCCAGTGA
AGTTCGAGCCAGTGGTGTGGATTTAAGTTTTGCTCCGGTGGTCGATCTTGGGCGTGGCAATCGTGCGATTGGCGATCGTG
CTTTCAGTGATGATCCGCACGTGGTGGCGGCGTTTGCCAAGGCTTATGTGCAGGGGATGCATGCTGCTGGTATGCCAGTG
ACGCTTAAGCATTTTCCTGGGCATGGTAGTGTTCTGGAGGATACGCACGTTGATCTTGCAGTGGATGTGCGTGCGTTGGA
AACGCTTGAGTCTGAGGATTTGGTGCCGTTTGCGGCAGGCATTGCTGCCGGTGCGGATGCAGTGATGATGGCACATGTAG
TTTATCCAAATGTCGCGCCTGAACCGGCAGGTTTTTCTGCGCATTGGATCGAGGTTATTTTACGTGGGCGCATGGGGTTT
CGGGGGGTGGTTTTTTCTGATGACATCGGTATGGCTGCTGTGCGTGGCGTTGGTGGTGTTGTTGGCTGTGTGCACGCGCA
TCTTGATGCTGGTTGTGATGTGGTTCTGGTGTGTCATCCGGAATTGGTGAACGATGCGCTGTCTGCTGTTGCTGGCCGTC
GTTCCAATACGGCTGCTCTTATTGGTTTGATCGGTCGCGGTGTGCTTGGTTGGGATGGGCTACTGGCCGATGTTCGTTAT
GGTTCCATTCAATCCCATTTATTTGAACGATTCGGAACATCCACTTGA

Upstream 100 bases:

>100_bases
GGTGGGAACTATTGCGCATGGTGTCTGATGTGCGCGCCGTTATCTTTGTTGCTATGTCGTGTTTGTGTCTCTGTGGTGTT
GTGAGCCGGAGGTTTTTGCA

Downstream 100 bases:

>100_bases
TGTCTAACTTCACTATTTCTCAGATACTTGCTCGGGCTGATTTATTGGTAGACCGTCCCAGTATTGATGTGGCTATTGCG
CATATCGCCGATGACATCGC

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLLIGVAGTTLSAQEVDWLQDDAVAGVVLFKRNFASRAQIVELSAALREAAPRPLLLAVDQEGGRVQRFHEGYSALPPLQ
GIGALYVRDPEAALELAFEHAWLMASEVRASGVDLSFAPVVDLGRGNRAIGDRAFSDDPHVVAAFAKAYVQGMHAAGMPV
TLKHFPGHGSVLEDTHVDLAVDVRALETLESEDLVPFAAGIAAGADAVMMAHVVYPNVAPEPAGFSAHWIEVILRGRMGF
RGVVFSDDIGMAAVRGVGGVVGCVHAHLDAGCDVVLVCHPELVNDALSAVAGRRSNTAALIGLIGRGVLGWDGLLADVRY
GSIQSHLFERFGTST

Sequences:

>Translated_335_residues
MLLIGVAGTTLSAQEVDWLQDDAVAGVVLFKRNFASRAQIVELSAALREAAPRPLLLAVDQEGGRVQRFHEGYSALPPLQ
GIGALYVRDPEAALELAFEHAWLMASEVRASGVDLSFAPVVDLGRGNRAIGDRAFSDDPHVVAAFAKAYVQGMHAAGMPV
TLKHFPGHGSVLEDTHVDLAVDVRALETLESEDLVPFAAGIAAGADAVMMAHVVYPNVAPEPAGFSAHWIEVILRGRMGF
RGVVFSDDIGMAAVRGVGGVVGCVHAHLDAGCDVVLVCHPELVNDALSAVAGRRSNTAALIGLIGRGVLGWDGLLADVRY
GSIQSHLFERFGTST
>Mature_335_residues
MLLIGVAGTTLSAQEVDWLQDDAVAGVVLFKRNFASRAQIVELSAALREAAPRPLLLAVDQEGGRVQRFHEGYSALPPLQ
GIGALYVRDPEAALELAFEHAWLMASEVRASGVDLSFAPVVDLGRGNRAIGDRAFSDDPHVVAAFAKAYVQGMHAAGMPV
TLKHFPGHGSVLEDTHVDLAVDVRALETLESEDLVPFAAGIAAGADAVMMAHVVYPNVAPEPAGFSAHWIEVILRGRMGF
RGVVFSDDIGMAAVRGVGGVVGCVHAHLDAGCDVVLVCHPELVNDALSAVAGRRSNTAALIGLIGRGVLGWDGLLADVRY
GSIQSHLFERFGTST

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily

Homologues:

Organism=Escherichia coli, GI1787350, Length=331, Percent_Identity=40.1812688821752, Blast_Score=234, Evalue=8e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAGZ_XYLF2 (B2I6G9)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830153.1
- ProteinModelPortal:   B2I6G9
- SMR:   B2I6G9
- GeneID:   6203766
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1468
- HOGENOM:   HBG617255
- OMA:   DLTMEGA
- ProtClustDB:   PRK05337
- GO:   GO:0005737
- HAMAP:   MF_00364
- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853
- Gene3D:   G3DSA:3.20.20.300

Pfam domain/function: PF00933 Glyco_hydro_3; SSF51445 Glyco_hydro_cat

EC number: =3.2.1.52

Molecular weight: Translated: 35295; Mature: 35295

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3

Important sites: ACT_SITE 247-247

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIGVAGTTLSAQEVDWLQDDAVAGVVLFKRNFASRAQIVELSAALREAAPRPLLLAVD
CEEEEECCCCCCHHHCCHHHHCHHHEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEE
QEGGRVQRFHEGYSALPPLQGIGALYVRDPEAALELAFEHAWLMASEVRASGVDLSFAPV
CCCCHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEECCE
VDLGRGNRAIGDRAFSDDPHVVAAFAKAYVQGMHAAGMPVTLKHFPGHGSVLEDTHVDLA
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEECCCCCEEE
VDVRALETLESEDLVPFAAGIAAGADAVMMAHVVYPNVAPEPAGFSAHWIEVILRGRMGF
EEHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCC
RGVVFSDDIGMAAVRGVGGVVGCVHAHLDAGCDVVLVCHPELVNDALSAVAGRRSNTAAL
CEEEEECCCCHHHHHHCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHCCCCCHHHH
IGLIGRGVLGWDGLLADVRYGSIQSHLFERFGTST
HHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLLIGVAGTTLSAQEVDWLQDDAVAGVVLFKRNFASRAQIVELSAALREAAPRPLLLAVD
CEEEEECCCCCCHHHCCHHHHCHHHEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEE
QEGGRVQRFHEGYSALPPLQGIGALYVRDPEAALELAFEHAWLMASEVRASGVDLSFAPV
CCCCHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEECCE
VDLGRGNRAIGDRAFSDDPHVVAAFAKAYVQGMHAAGMPVTLKHFPGHGSVLEDTHVDLA
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEECCCCCEEE
VDVRALETLESEDLVPFAAGIAAGADAVMMAHVVYPNVAPEPAGFSAHWIEVILRGRMGF
EEHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCC
RGVVFSDDIGMAAVRGVGGVVGCVHAHLDAGCDVVLVCHPELVNDALSAVAGRRSNTAAL
CEEEEECCCCHHHHHHCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHCCCCCHHHH
IGLIGRGVLGWDGLLADVRYGSIQSHLFERFGTST
HHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA