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The map label for this gene is pheA [H]

Identifier: 182681967

GI number: 182681967

Start: 1592479

End: 1593603

Strand: Reverse

Name: pheA [H]

Synonym: XfasM23_1442

Alternate gene names: 182681967

Gene position: 1593603-1592479 (Counterclockwise)

Preceding gene: 182681968

Following gene: 182681966

Centisome position: 62.85

GC content: 49.87

Gene sequence:

>1125_bases
ATGACTAAGCCGGTTAATACTACTGCTGACAAGGTTGCTCTGTCTGACACGGCATTGGCCGATATCCGCACTAAAATCGA
TAAGATTGACCGTGATATTCAGACATTGATTGCCGAACGTGCGTGTTATGCCCAGCAAGTCGGTCAGGCAAAAAGCAAAC
TTGCCGCTGCGATGGATTACTACCGCCCCGAGCGTGAAGCGCAGGTGCTACGTATGGTGGTGGAACGCAATGAAGGTCCG
TTGTCAGATGAAGTGCTAGTCCGCTTATTCCGTGAAATTATGTCTGCCTGTTTAGCCCAGCAGGAACCATTGAAGATTGG
TTACCTTGGTCCGGAAGGCACCTTTAGCCAACAAGCAGTGCTCAAACACTTTGGCCATTATGTCCTTGGCGAGCCTATGG
CCAGTATTGAGGAGGTGTTCCAGGAGGTCGAGGCCGGTCATACCGATTTCGGAGTAGTGCCGGTGGAGAATTCAGGTCAT
GGAACAATCCAGGTTACGCTGGATTTGTTTTTGAATTCTAAATTGAAAATCTGTGGCGAGATTGAGTTGCGCGTGCATCA
ATATCTGATGTCTCGTAGTGGTCGCCTTGAAGACATTCATCGGATCTATGCGCACCCGCAGTCGTTTGCGCAGACCGCCT
GTTGGCTACGTGCCAATCTGCCTCATGTTGAGAAAATCCCTGTGTCTAGCAACGCCGAAGGTGCACGTCGTGCCTCCAAT
GCTAACGATGCAGCTTCGATCGGTAGCGAGAGCGCCGCGCGAGTGTATGCGTTGAGCAAGGTGTTCATACACTCAATTGA
AGATGAGCAGGACAATACAACGCGTTTTCTGGTGATCGGTCGTCGGATATTTGCGCCTTCCGGATGCGATCGTACTTCGA
TTCTTGTGTTTATTCGTGACAACCCTGGCGCATTGTTTGAAGTGCTTGGTTCATTTGCGCGTCACGGTATCAACATGAAT
CGTATTGAATCGCGCCCTTCCCATCAGGTCAGATGGGAGTATGTCTTTTTTATTGATTTGCTTGGCCATGTTGAGGATGA
ACCGATGAAACAGGCACTGGCTGAATTGGAGCAACATGCGGTGAAGGTCAAGATCCTCGGAGCCTATCCAATTGCCCTTC
TATGA

Upstream 100 bases:

>100_bases
TTTCAACAGCGCTATGGTTGATTCTGGCGCCCATACCACACCGTTTGAGCGGTGATGACGATGAGGCATTTTTGCTCGTG
ACTACCAAGCTGGTTTCCAA

Downstream 100 bases:

>100_bases
TGCTTGAGTATTTCTGTCCAGGAGCGACACGCATTACCGCAGCCTCGGCGGTTTGTATTGTCGTCGCTCTCAGTTGAAGA
AACCTAGTATGAGTCATAGA

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MTKPVNTTADKVALSDTALADIRTKIDKIDRDIQTLIAERACYAQQVGQAKSKLAAAMDYYRPEREAQVLRMVVERNEGP
LSDEVLVRLFREIMSACLAQQEPLKIGYLGPEGTFSQQAVLKHFGHYVLGEPMASIEEVFQEVEAGHTDFGVVPVENSGH
GTIQVTLDLFLNSKLKICGEIELRVHQYLMSRSGRLEDIHRIYAHPQSFAQTACWLRANLPHVEKIPVSSNAEGARRASN
ANDAASIGSESAARVYALSKVFIHSIEDEQDNTTRFLVIGRRIFAPSGCDRTSILVFIRDNPGALFEVLGSFARHGINMN
RIESRPSHQVRWEYVFFIDLLGHVEDEPMKQALAELEQHAVKVKILGAYPIALL

Sequences:

>Translated_374_residues
MTKPVNTTADKVALSDTALADIRTKIDKIDRDIQTLIAERACYAQQVGQAKSKLAAAMDYYRPEREAQVLRMVVERNEGP
LSDEVLVRLFREIMSACLAQQEPLKIGYLGPEGTFSQQAVLKHFGHYVLGEPMASIEEVFQEVEAGHTDFGVVPVENSGH
GTIQVTLDLFLNSKLKICGEIELRVHQYLMSRSGRLEDIHRIYAHPQSFAQTACWLRANLPHVEKIPVSSNAEGARRASN
ANDAASIGSESAARVYALSKVFIHSIEDEQDNTTRFLVIGRRIFAPSGCDRTSILVFIRDNPGALFEVLGSFARHGINMN
RIESRPSHQVRWEYVFFIDLLGHVEDEPMKQALAELEQHAVKVKILGAYPIALL
>Mature_373_residues
TKPVNTTADKVALSDTALADIRTKIDKIDRDIQTLIAERACYAQQVGQAKSKLAAAMDYYRPEREAQVLRMVVERNEGPL
SDEVLVRLFREIMSACLAQQEPLKIGYLGPEGTFSQQAVLKHFGHYVLGEPMASIEEVFQEVEAGHTDFGVVPVENSGHG
TIQVTLDLFLNSKLKICGEIELRVHQYLMSRSGRLEDIHRIYAHPQSFAQTACWLRANLPHVEKIPVSSNAEGARRASNA
NDAASIGSESAARVYALSKVFIHSIEDEQDNTTRFLVIGRRIFAPSGCDRTSILVFIRDNPGALFEVLGSFARHGINMNR
IESRPSHQVRWEYVFFIDLLGHVEDEPMKQALAELEQHAVKVKILGAYPIALL

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=384, Percent_Identity=30.7291666666667, Blast_Score=169, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6324013, Length=340, Percent_Identity=30, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 41765; Mature: 41634

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPVNTTADKVALSDTALADIRTKIDKIDRDIQTLIAERACYAQQVGQAKSKLAAAMDY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRPEREAQVLRMVVERNEGPLSDEVLVRLFREIMSACLAQQEPLKIGYLGPEGTFSQQAV
HCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
LKHFGHYVLGEPMASIEEVFQEVEAGHTDFGVVPVENSGHGTIQVTLDLFLNSKLKICGE
HHHCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEEEEECCCCEEEEHH
IELRVHQYLMSRSGRLEDIHRIYAHPQSFAQTACWLRANLPHVEKIPVSSNAEGARRASN
HHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHCCC
ANDAASIGSESAARVYALSKVFIHSIEDEQDNTTRFLVIGRRIFAPSGCDRTSILVFIRD
CCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEECCCCCCCCEEEEEEEC
NPGALFEVLGSFARHGINMNRIESRPSHQVRWEYVFFIDLLGHVEDEPMKQALAELEQHA
CCCHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHCC
VKVKILGAYPIALL
EEEEEEECCCHHCC
>Mature Secondary Structure 
TKPVNTTADKVALSDTALADIRTKIDKIDRDIQTLIAERACYAQQVGQAKSKLAAAMDY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRPEREAQVLRMVVERNEGPLSDEVLVRLFREIMSACLAQQEPLKIGYLGPEGTFSQQAV
HCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
LKHFGHYVLGEPMASIEEVFQEVEAGHTDFGVVPVENSGHGTIQVTLDLFLNSKLKICGE
HHHCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEEEEECCCCEEEEHH
IELRVHQYLMSRSGRLEDIHRIYAHPQSFAQTACWLRANLPHVEKIPVSSNAEGARRASN
HHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHCCC
ANDAASIGSESAARVYALSKVFIHSIEDEQDNTTRFLVIGRRIFAPSGCDRTSILVFIRD
CCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEECCCCCCCCEEEEEEEC
NPGALFEVLGSFARHGINMNRIESRPSHQVRWEYVFFIDLLGHVEDEPMKQALAELEQHA
CCCHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHCC
VKVKILGAYPIALL
EEEEEEECCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1919506; 10368439 [H]