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The map label for this gene is aroA [H]

Identifier: 182681966

GI number: 182681966

Start: 1591062

End: 1592390

Strand: Reverse

Name: aroA [H]

Synonym: XfasM23_1441

Alternate gene names: 182681966

Gene position: 1592390-1591062 (Counterclockwise)

Preceding gene: 182681967

Following gene: 182681965

Centisome position: 62.8

GC content: 54.7

Gene sequence:

>1329_bases
ATGAGTCATAGAACGCATTACTATTGGATCGCACACCAGGGTACCCCACTGCATGGCGTCCTGAGTATCCCCGGCGATAA
ATCAATCTCTCATCGTGCAGTCATGTTTGCTGCCCTTGCGGATGGCACGTCACGTATTGATGGCTTTCTTGAGGCGGAGG
ATACGCGCTCTACAGCAGCGATCTTGGCCCGATTGGGTGTGCGTATCGAAACTCCCTCATTCACGCAGCGCATCGTCCAT
GGTGTTGGTGTGGATGGACTCCAGGCATCGGATATTGCCCTGGATTGTGGCAATGCAGGCACTGGCATGCGCCTGCTCGC
TGGTTTGCTGGTAGCGCAGCCTTTTGACAGCGTTTTAGTCGGAGATGCATCACTGTCCAAGCGACCGATGCGACGTGTGA
CGGATCCGCTGTCACAGATGGGCGCACGTATCGATACCAGCGACGATGGTACTCCACCGCTGCGTATTTACGGTGGTCAA
TTACTCCGCGGTATCGATTTTATCTCCCCAGTGGCCAGTGCTCAGATCAAGTCAGCGGTGTTGCTGGCTGGATTGTATGC
ACGTAACGAAACGGTAGTGCGTGAACCGCACCCGACGCGTGATTACACCGAGCGTATGCTCACTGCGTTTGGTGTGGACA
TTGATGTTTCCACAGGGTGCGTGCGGTTGCGTGGTGGGCAACGGTTATGTGCTACCAATATTACAATCCCGGCTGATTTT
TCCTCAGCTGCGTTTTATCTGGTTGCAGCCAGCGTGATTCCTGGCTCTGATATCACCCTGCGTGCTGTTGGACTCAATCC
GCGTCGTATTGGTTTGTTAACTGTGTTGCGGCTGATGGGGGCAGATATTGTTGAATCCAATCGCCATGAACAGGGTGGTG
AGCCGGTTGCTGACCTACGTGTGCGTTATGCGTCACTCCAGGGCACGCGTGTTCCTGAAGATTTGGTGCCGGATATGATT
GACGAATTCCCTGCCTTGTTTGTCGCTGCAGCGGCAGCCGAAGGTCAAACGGTAGTGAGTGGTGCGGCTGAACTACGCGT
TAAAGAATCGGACCGGTTGGCTGCGATGGTGACAGGCTTGCGCGTGCTTGGCGTTCAGGTGGATGAGACCGCCGACGGGG
CAACGATTCATGGAGGGCCCATCGGTCATGGCACCATCAACAGCCATGGCGATCATCGCATCGCCATGGCGTTTTCAATT
GCAGGGCAGCTTTCCGTCAGTACAGTACGTATTGAAGATGTCGCCAATGTTGCGACTTCTTTTCCAGACTATGAGACGTT
AGCGCGCAGCGCTGGTTTCGGTCTTGAGGTGTACTGCGATCCAGCATGA

Upstream 100 bases:

>100_bases
GCCCTTCTATGATGCTTGAGTATTTCTGTCCAGGAGCGACACGCATTACCGCAGCCTCGGCGGTTTGTATTGTCGTCGCT
CTCAGTTGAAGAAACCTAGT

Downstream 100 bases:

>100_bases
ATGAACGCCATTAATATCTGTACTGCCTTGTAAGCCATGCGATGGTTGTTCTCACTTAAAGAAGCCCAGCAGTTCTTTCG
TGTTTCTTTCACTTGTTCTT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSHRTHYYWIAHQGTPLHGVLSIPGDKSISHRAVMFAALADGTSRIDGFLEAEDTRSTAAILARLGVRIETPSFTQRIVH
GVGVDGLQASDIALDCGNAGTGMRLLAGLLVAQPFDSVLVGDASLSKRPMRRVTDPLSQMGARIDTSDDGTPPLRIYGGQ
LLRGIDFISPVASAQIKSAVLLAGLYARNETVVREPHPTRDYTERMLTAFGVDIDVSTGCVRLRGGQRLCATNITIPADF
SSAAFYLVAASVIPGSDITLRAVGLNPRRIGLLTVLRLMGADIVESNRHEQGGEPVADLRVRYASLQGTRVPEDLVPDMI
DEFPALFVAAAAAEGQTVVSGAAELRVKESDRLAAMVTGLRVLGVQVDETADGATIHGGPIGHGTINSHGDHRIAMAFSI
AGQLSVSTVRIEDVANVATSFPDYETLARSAGFGLEVYCDPA

Sequences:

>Translated_442_residues
MSHRTHYYWIAHQGTPLHGVLSIPGDKSISHRAVMFAALADGTSRIDGFLEAEDTRSTAAILARLGVRIETPSFTQRIVH
GVGVDGLQASDIALDCGNAGTGMRLLAGLLVAQPFDSVLVGDASLSKRPMRRVTDPLSQMGARIDTSDDGTPPLRIYGGQ
LLRGIDFISPVASAQIKSAVLLAGLYARNETVVREPHPTRDYTERMLTAFGVDIDVSTGCVRLRGGQRLCATNITIPADF
SSAAFYLVAASVIPGSDITLRAVGLNPRRIGLLTVLRLMGADIVESNRHEQGGEPVADLRVRYASLQGTRVPEDLVPDMI
DEFPALFVAAAAAEGQTVVSGAAELRVKESDRLAAMVTGLRVLGVQVDETADGATIHGGPIGHGTINSHGDHRIAMAFSI
AGQLSVSTVRIEDVANVATSFPDYETLARSAGFGLEVYCDPA
>Mature_441_residues
SHRTHYYWIAHQGTPLHGVLSIPGDKSISHRAVMFAALADGTSRIDGFLEAEDTRSTAAILARLGVRIETPSFTQRIVHG
VGVDGLQASDIALDCGNAGTGMRLLAGLLVAQPFDSVLVGDASLSKRPMRRVTDPLSQMGARIDTSDDGTPPLRIYGGQL
LRGIDFISPVASAQIKSAVLLAGLYARNETVVREPHPTRDYTERMLTAFGVDIDVSTGCVRLRGGQRLCATNITIPADFS
SAAFYLVAASVIPGSDITLRAVGLNPRRIGLLTVLRLMGADIVESNRHEQGGEPVADLRVRYASLQGTRVPEDLVPDMID
EFPALFVAAAAAEGQTVVSGAAELRVKESDRLAAMVTGLRVLGVQVDETADGATIHGGPIGHGTINSHGDHRIAMAFSIA
GQLSVSTVRIEDVANVATSFPDYETLARSAGFGLEVYCDPA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=426, Percent_Identity=32.3943661971831, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320332, Length=438, Percent_Identity=28.5388127853881, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46844; Mature: 46713

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHRTHYYWIAHQGTPLHGVLSIPGDKSISHRAVMFAALADGTSRIDGFLEAEDTRSTAA
CCCCEEEEEEEECCCCCEEEEECCCCCCCCHHEEEEEEHHCCHHHHCCEEECCCCHHHHH
ILARLGVRIETPSFTQRIVHGVGVDGLQASDIALDCGNAGTGMRLLAGLLVAQPFDSVLV
HHHHHCCEEECCHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEE
GDASLSKRPMRRVTDPLSQMGARIDTSDDGTPPLRIYGGQLLRGIDFISPVASAQIKSAV
CCCHHCCCHHHHHHHHHHHHCCEECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
LLAGLYARNETVVREPHPTRDYTERMLTAFGVDIDVSTGCVRLRGGQRLCATNITIPADF
HHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCEEECCCCEEEECCCCEEEEECCEECCCC
SSAAFYLVAASVIPGSDITLRAVGLNPRRIGLLTVLRLMGADIVESNRHEQGGEPVADLR
CCCEEEEEEEHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHH
VRYASLQGTRVPEDLVPDMIDEFPALFVAAAAAEGQTVVSGAAELRVKESDRLAAMVTGL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHEEECCCCHHHHHHHHH
RVLGVQVDETADGATIHGGPIGHGTINSHGDHRIAMAFSIAGQLSVSTVRIEDVANVATS
HHEEEEEECCCCCCEECCCCCCCCCCCCCCCCEEEEEEEECCCEEEEEEEHHHHHHHHHC
FPDYETLARSAGFGLEVYCDPA
CCCHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure 
SHRTHYYWIAHQGTPLHGVLSIPGDKSISHRAVMFAALADGTSRIDGFLEAEDTRSTAA
CCCEEEEEEEECCCCCEEEEECCCCCCCCHHEEEEEEHHCCHHHHCCEEECCCCHHHHH
ILARLGVRIETPSFTQRIVHGVGVDGLQASDIALDCGNAGTGMRLLAGLLVAQPFDSVLV
HHHHHCCEEECCHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEE
GDASLSKRPMRRVTDPLSQMGARIDTSDDGTPPLRIYGGQLLRGIDFISPVASAQIKSAV
CCCHHCCCHHHHHHHHHHHHCCEECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
LLAGLYARNETVVREPHPTRDYTERMLTAFGVDIDVSTGCVRLRGGQRLCATNITIPADF
HHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCEEECCCCEEEECCCCEEEEECCEECCCC
SSAAFYLVAASVIPGSDITLRAVGLNPRRIGLLTVLRLMGADIVESNRHEQGGEPVADLR
CCCEEEEEEEHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHH
VRYASLQGTRVPEDLVPDMIDEFPALFVAAAAAEGQTVVSGAAELRVKESDRLAAMVTGL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHEEECCCCHHHHHHHHH
RVLGVQVDETADGATIHGGPIGHGTINSHGDHRIAMAFSIAGQLSVSTVRIEDVANVATS
HHEEEEEECCCCCCEECCCCCCCCCCCCCCCCEEEEEEEECCCEEEEEEEHHHHHHHHHC
FPDYETLARSAGFGLEVYCDPA
CCCHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]