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The map label for this gene is prmA

Identifier: 182681868

GI number: 182681868

Start: 1474357

End: 1475277

Strand: Direct

Name: prmA

Synonym: XfasM23_1336

Alternate gene names: 182681868

Gene position: 1474357-1475277 (Clockwise)

Preceding gene: 182681867

Following gene: 182681869

Centisome position: 58.14

GC content: 60.69

Gene sequence:

>921_bases
ATGGCGTTTTTAGAGGTCAGTGTGCAGTGTCAGGAGAGGAGTCAGGCGCGCTATGAGGAGGTCTTGGAGAGTTTCGGTGC
GTTGGCAGTGACGTTGTTGGATGCCGATGCGGATACGGTTCGGGAGCGGGGGGTGTTTGAGCCGGGGGTGGGGGAAACGG
TGTTGTGGGATGTTGTGGTGTTGAGTGCGTTGTTTCCGGTGGAAACGGATGCGTTGGGGTTGTTGGCTGGGCTGGAGGGT
GCGGAGCCAGGGTTGGATTGGGGGGGAGTCCGTTTCCGTGTGGTGGTGGATGAGGATTGGGAGCGGGTGTGGATGGATCA
GTTTCAAGCGATGCGTTTTGGGGAGCGTACGTTCATTGTGCCGTGGAATCAGGCGGTGCCTGTGGAGGCGTCGGGGATGG
ATGCGGCGGTGGTGCGGTTGGATCCGGGGTTGGCGTTTGGTTCGGGGACGCATCCAACAACGGGGTTGTGTCTGCGTTGG
CTGGATCGGCTGGGAGGGGATGGGGTGTTAGGGGGGGGGGATGTGCTCGATTTTGGGTGTGGTTCGGGCATTTTGGCGCT
GGCCGCTCTGAAGTTGGGGGCGGTTTATGCGGTGGGTGTGGACAATGATCCGCAGGCGTTGTTGGCAAGTCGGGAGAATG
CGCTGCGTAATAGGGTGGCGGAGCGGTTGGAGGTGTATTTGCCTGCGGAGGCGCCGGTACGCAGGTATCCGGTGGTGGTG
GCCAATATTTTGGCGTCAACGTTGGTGGCGTTGGCAGAGCGGTTGGCGGGGTATGTTGCGCCGGGGGGACGGTTGGCGCT
GTCAGGGATTTTGCGGGGGGAGGAGGAGGAGGTGTTGCGCTGTTATGCGGTGTGGTTGGATGTGTTGGGTTGTGAGGAGG
AGGATGGTTGGATACGGATTGATGGGGTACGCCGTTGTTGA

Upstream 100 bases:

>100_bases
GGTGGGCTGATGGGAGGTTGAGGGGAGTTTTGGCTGTGGTGGGGTGTTGGGGGTGGGTGGTGACAGGTGGAACAATGGAC
GGTTTAAAGGGGATGTGGTT

Downstream 100 bases:

>100_bases
GAGGGGATGGGTGTTGCTGGCGGTGATGTGGAATGCGGTAGCGTTGGCTGCCCCATCAAGCAGACAATAGATTGGTAATC
GACTGAGTAAGGGGTCTTTG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MAFLEVSVQCQERSQARYEEVLESFGALAVTLLDADADTVRERGVFEPGVGETVLWDVVVLSALFPVETDALGLLAGLEG
AEPGLDWGGVRFRVVVDEDWERVWMDQFQAMRFGERTFIVPWNQAVPVEASGMDAAVVRLDPGLAFGSGTHPTTGLCLRW
LDRLGGDGVLGGGDVLDFGCGSGILALAALKLGAVYAVGVDNDPQALLASRENALRNRVAERLEVYLPAEAPVRRYPVVV
ANILASTLVALAERLAGYVAPGGRLALSGILRGEEEEVLRCYAVWLDVLGCEEEDGWIRIDGVRRC

Sequences:

>Translated_306_residues
MAFLEVSVQCQERSQARYEEVLESFGALAVTLLDADADTVRERGVFEPGVGETVLWDVVVLSALFPVETDALGLLAGLEG
AEPGLDWGGVRFRVVVDEDWERVWMDQFQAMRFGERTFIVPWNQAVPVEASGMDAAVVRLDPGLAFGSGTHPTTGLCLRW
LDRLGGDGVLGGGDVLDFGCGSGILALAALKLGAVYAVGVDNDPQALLASRENALRNRVAERLEVYLPAEAPVRRYPVVV
ANILASTLVALAERLAGYVAPGGRLALSGILRGEEEEVLRCYAVWLDVLGCEEEDGWIRIDGVRRC
>Mature_305_residues
AFLEVSVQCQERSQARYEEVLESFGALAVTLLDADADTVRERGVFEPGVGETVLWDVVVLSALFPVETDALGLLAGLEGA
EPGLDWGGVRFRVVVDEDWERVWMDQFQAMRFGERTFIVPWNQAVPVEASGMDAAVVRLDPGLAFGSGTHPTTGLCLRWL
DRLGGDGVLGGGDVLDFGCGSGILALAALKLGAVYAVGVDNDPQALLASRENALRNRVAERLEVYLPAEAPVRRYPVVVA
NILASTLVALAERLAGYVAPGGRLALSGILRGEEEEVLRCYAVWLDVLGCEEEDGWIRIDGVRRC

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=307, Percent_Identity=45.2768729641694, Blast_Score=189, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33030; Mature: 32899

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFLEVSVQCQERSQARYEEVLESFGALAVTLLDADADTVRERGVFEPGVGETVLWDVVV
CCEEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCCCCCCHHHHHHHHH
LSALFPVETDALGLLAGLEGAEPGLDWGGVRFRVVVDEDWERVWMDQFQAMRFGERTFIV
HHHHCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEE
PWNQAVPVEASGMDAAVVRLDPGLAFGSGTHPTTGLCLRWLDRLGGDGVLGGGDVLDFGC
ECCCCCCCCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCC
GSGILALAALKLGAVYAVGVDNDPQALLASRENALRNRVAERLEVYLPAEAPVRRYPVVV
CCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHH
ANILASTLVALAERLAGYVAPGGRLALSGILRGEEEEVLRCYAVWLDVLGCEEEDGWIRI
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
DGVRRC
CCCCCC
>Mature Secondary Structure 
AFLEVSVQCQERSQARYEEVLESFGALAVTLLDADADTVRERGVFEPGVGETVLWDVVV
CEEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCCCCCCHHHHHHHHH
LSALFPVETDALGLLAGLEGAEPGLDWGGVRFRVVVDEDWERVWMDQFQAMRFGERTFIV
HHHHCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEE
PWNQAVPVEASGMDAAVVRLDPGLAFGSGTHPTTGLCLRWLDRLGGDGVLGGGDVLDFGC
ECCCCCCCCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCC
GSGILALAALKLGAVYAVGVDNDPQALLASRENALRNRVAERLEVYLPAEAPVRRYPVVV
CCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHH
ANILASTLVALAERLAGYVAPGGRLALSGILRGEEEEVLRCYAVWLDVLGCEEEDGWIRI
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
DGVRRC
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]