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The map label for this gene is nadD

Identifier: 182681847

GI number: 182681847

Start: 1445701

End: 1446369

Strand: Direct

Name: nadD

Synonym: XfasM23_1312

Alternate gene names: 182681847

Gene position: 1445701-1446369 (Clockwise)

Preceding gene: 182681846

Following gene: 182681848

Centisome position: 57.01

GC content: 57.4

Gene sequence:

>669_bases
ATGCCCAGCCTGCACGTATTTTATGGCGGCACCTTTGATCCTGTGCATGTCGGCCACTTAGCCATCGCACGCGCAGCGCA
TGCAGCACTGCAAGCCCCTATCGCCCTGATCCCCTCCGCCGATCCCCCACATCGCCCCACACCCGGCTCCTCAAGCATGG
ATCGCTTACGCATGCTGCAACTGGCAGTCTCCAAGGAACCTGGATTGTCCGCAGACCCACGCGAACTACAACGCGCCGCG
CGACAAAACCGATCATCGTACACCGTCGACACCCTGACCGAAGTGCGCAGCGAACTCGGCCCCAAAACATCAATTATCTG
GTTACTGGGTGCTGACGCCTTCGTCAACCTGAGCAACTGGAAAGATTGGCAAATGCTACCGGAACTCACACACCTGGTCA
TCGCCAACCGCCCAGGCATCACACTGCAAACACAACTGCCACCCAAGATGGCTACCGTCTTCAATCATCGCTGGGTCCAA
GATCCAGCCACACTACGCAAGACACCACACGGCCATCTCTGGCTATTGAACCAACACCCAAACCCAAGCTCAGCAAGCAA
AGTACGCGCTGCTATCAGCGCCGCCGCCCACTGGGAAGCCGACCTCACACCTGAAGTCGCACAGTACATACGCACACACG
GCCTATACGGCATCCATGACATCAATTAA

Upstream 100 bases:

>100_bases
ATGCCTGGCTGTCACTCGAACGTCTCATGGTGGCAGTAGCAGAAGCAGATGCAACACGTCTGCTAGCATAACGCCCCCTT
CCTGGACACCGAGCGATGCT

Downstream 100 bases:

>100_bases
CCACAAGCTTATCTATAATGCCTCCCCCAACGTTCACTCGAGTTACCACGTTGACCAATCAAGCGCATCTCATCAAAACC
ACAATCCCCAACCCACCACC

Product: nicotinic acid mononucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MPSLHVFYGGTFDPVHVGHLAIARAAHAALQAPIALIPSADPPHRPTPGSSSMDRLRMLQLAVSKEPGLSADPRELQRAA
RQNRSSYTVDTLTEVRSELGPKTSIIWLLGADAFVNLSNWKDWQMLPELTHLVIANRPGITLQTQLPPKMATVFNHRWVQ
DPATLRKTPHGHLWLLNQHPNPSSASKVRAAISAAAHWEADLTPEVAQYIRTHGLYGIHDIN

Sequences:

>Translated_222_residues
MPSLHVFYGGTFDPVHVGHLAIARAAHAALQAPIALIPSADPPHRPTPGSSSMDRLRMLQLAVSKEPGLSADPRELQRAA
RQNRSSYTVDTLTEVRSELGPKTSIIWLLGADAFVNLSNWKDWQMLPELTHLVIANRPGITLQTQLPPKMATVFNHRWVQ
DPATLRKTPHGHLWLLNQHPNPSSASKVRAAISAAAHWEADLTPEVAQYIRTHGLYGIHDIN
>Mature_221_residues
PSLHVFYGGTFDPVHVGHLAIARAAHAALQAPIALIPSADPPHRPTPGSSSMDRLRMLQLAVSKEPGLSADPRELQRAAR
QNRSSYTVDTLTEVRSELGPKTSIIWLLGADAFVNLSNWKDWQMLPELTHLVIANRPGITLQTQLPPKMATVFNHRWVQD
PATLRKTPHGHLWLLNQHPNPSSASKVRAAISAAAHWEADLTPEVAQYIRTHGLYGIHDIN

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=223, Percent_Identity=34.9775784753363, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_XYLF2 (B2I5T8)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830007.1
- ProteinModelPortal:   B2I5T8
- SMR:   B2I5T8
- GeneID:   6203827
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1312
- HOGENOM:   HBG739448
- OMA:   IQCAPAG
- ProtClustDB:   PRK00071
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.18

Molecular weight: Translated: 24510; Mature: 24379

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLHVFYGGTFDPVHVGHLAIARAAHAALQAPIALIPSADPPHRPTPGSSSMDRLRMLQ
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHH
LAVSKEPGLSADPRELQRAARQNRSSYTVDTLTEVRSELGPKTSIIWLLGADAFVNLSNW
HHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCEEEECCCC
KDWQMLPELTHLVIANRPGITLQTQLPPKMATVFNHRWVQDPATLRKTPHGHLWLLNQHP
CCHHHHHHHHHHHEECCCCEEEEECCCHHHHHHHHCCCCCCCHHHHCCCCCCEEEEECCC
NPSSASKVRAAISAAAHWEADLTPEVAQYIRTHGLYGIHDIN
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
PSLHVFYGGTFDPVHVGHLAIARAAHAALQAPIALIPSADPPHRPTPGSSSMDRLRMLQ
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHH
LAVSKEPGLSADPRELQRAARQNRSSYTVDTLTEVRSELGPKTSIIWLLGADAFVNLSNW
HHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCEEEECCCC
KDWQMLPELTHLVIANRPGITLQTQLPPKMATVFNHRWVQDPATLRKTPHGHLWLLNQHP
CCHHHHHHHHHHHEECCCCEEEEECCCHHHHHHHHCCCCCCCHHHHCCCCCCEEEEECCC
NPSSASKVRAAISAAAHWEADLTPEVAQYIRTHGLYGIHDIN
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA