Click here to switch to the map view.

The map label for this gene is ruvA

Identifier: 182681488

GI number: 182681488

Start: 1107379

End: 1107963

Strand: Direct

Name: ruvA

Synonym: XfasM23_0942

Alternate gene names: 182681488

Gene position: 1107379-1107963 (Clockwise)

Preceding gene: 182681487

Following gene: 182681489

Centisome position: 43.67

GC content: 50.77

Gene sequence:

>585_bases
ATGATTGGTCGCTTGCGAGGGGTTTTGACTAGCAAAACGCCACCGTGGCTCGTGGTTGATGTGTGTGGAGTTGGCTACGA
ACTAGAGGTGCCGATGAGCACTTTTTGCGAATTGCCAGACGTCGGTTACGAGGTGAATTTGTTTACTCACTATACGCAGA
AGGATGATAGTGCCGCGTTGTACGGTTTTCTGAGCGAAAGTGAGCGGCGGCTATTCCGCCACCTGCAGCGGGTGAGTGGT
ATCGGTACCAAGATCGCTTTGGCGATTCTATCCAGCGTCAGCGTGGATACATTTGCGGGGTTAATCCAGGCTGGTGACGC
TAATGCATTAACGGTTATCCCAGGAGTTGGGAAGAAAACCGCTGAACGTATGCTGGTGGAGTTGAGAGACCGTGCTGCAG
ACTTCAACAATGGTATTTCCACCTCAGGCAAGCTCAATCTTGATACGGTATCTGAAGCTGCCTTGGCTTTGCAGCAACTC
GGTTATAAGCCAGCTGAGGCTGCACGTATGGCACGTGATGCCGGTACTGAGAGCGATGATGTTGCTATTGTCATCAAAAA
AGCGCTTCAAACCGTATTACGTTGA

Upstream 100 bases:

>100_bases
TGGAGCCGGAAATGATTAAAGGCCTGTGGGTGGTTTGGGGTCTCCTCATTAGAGCGGCGACCTGTGATGAGCATACGGCT
TTTTGTAAAGAGCATCACGT

Downstream 100 bases:

>100_bases
TCTTGGTTTATTTTCTACATTCACGTTATTAATGATTAACTTTACTTATTAGCCATGTCTACCTCTTCTCATTCAGGTGA
TTGCGCAGCAATCACCTCTA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MIGRLRGVLTSKTPPWLVVDVCGVGYELEVPMSTFCELPDVGYEVNLFTHYTQKDDSAALYGFLSESERRLFRHLQRVSG
IGTKIALAILSSVSVDTFAGLIQAGDANALTVIPGVGKKTAERMLVELRDRAADFNNGISTSGKLNLDTVSEAALALQQL
GYKPAEAARMARDAGTESDDVAIVIKKALQTVLR

Sequences:

>Translated_194_residues
MIGRLRGVLTSKTPPWLVVDVCGVGYELEVPMSTFCELPDVGYEVNLFTHYTQKDDSAALYGFLSESERRLFRHLQRVSG
IGTKIALAILSSVSVDTFAGLIQAGDANALTVIPGVGKKTAERMLVELRDRAADFNNGISTSGKLNLDTVSEAALALQQL
GYKPAEAARMARDAGTESDDVAIVIKKALQTVLR
>Mature_194_residues
MIGRLRGVLTSKTPPWLVVDVCGVGYELEVPMSTFCELPDVGYEVNLFTHYTQKDDSAALYGFLSESERRLFRHLQRVSG
IGTKIALAILSSVSVDTFAGLIQAGDANALTVIPGVGKKTAERMLVELRDRAADFNNGISTSGKLNLDTVSEAALALQQL
GYKPAEAARMARDAGTESDDVAIVIKKALQTVLR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=40.3940886699507, Blast_Score=164, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_XYLF2 (B2I4S9)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829648.1
- ProteinModelPortal:   B2I4S9
- SMR:   B2I4S9
- GeneID:   6203384
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0942
- HOGENOM:   HBG635309
- OMA:   LFGFAQK
- ProtClustDB:   PRK00116
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 20917; Mature: 20917

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLRGVLTSKTPPWLVVDVCGVGYELEVPMSTFCELPDVGYEVNLFTHYTQKDDSAAL
CCCCHHHHHCCCCCCEEEEEECCCCEEEECCHHHHCCCCCCCEEEEEEEEECCCCCCHHH
YGFLSESERRLFRHLQRVSGIGTKIALAILSSVSVDTFAGLIQAGDANALTVIPGVGKKT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCHHH
AERMLVELRDRAADFNNGISTSGKLNLDTVSEAALALQQLGYKPAEAARMARDAGTESDD
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
VAIVIKKALQTVLR
HHHHHHHHHHHHHC
>Mature Secondary Structure
MIGRLRGVLTSKTPPWLVVDVCGVGYELEVPMSTFCELPDVGYEVNLFTHYTQKDDSAAL
CCCCHHHHHCCCCCCEEEEEECCCCEEEECCHHHHCCCCCCCEEEEEEEEECCCCCCHHH
YGFLSESERRLFRHLQRVSGIGTKIALAILSSVSVDTFAGLIQAGDANALTVIPGVGKKT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCHHH
AERMLVELRDRAADFNNGISTSGKLNLDTVSEAALALQQLGYKPAEAARMARDAGTESDD
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
VAIVIKKALQTVLR
HHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA