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The map label for this gene is ruvC

Identifier: 182681487

GI number: 182681487

Start: 1106679

End: 1107293

Strand: Direct

Name: ruvC

Synonym: XfasM23_0941

Alternate gene names: 182681487

Gene position: 1106679-1107293 (Clockwise)

Preceding gene: 182681486

Following gene: 182681488

Centisome position: 43.64

GC content: 49.11

Gene sequence:

>615_bases
ATGTTGATTGCTATGGATACGCTCCATCTTTGTCTTAACTGTTCTTCCATCATTGATCACTTTGTCTTAATGTGTTCTCG
TATCGCTTATCAGATGACGCGTATCCTCGGTATTGATCCTGGATCACAGCGCACTGGAGTTGGTGTCATTGATGTCGATG
AGTATGGATGTAGTCACCATGTCTACCATGCACCATTGGTACTACTAGGTCAGAGTAGTTTTGCGGGGCGACTGAAGCAG
TTGTTGTTGGGTCTGAGCGCAGTGATTGAGGAGTACAGCCCAAAGGAAGTGGCCATTGAGAAGGTGTTTATGTCTAAAAA
TGCTGATTCAGCACTTAAGCTTGGTCAGGCGCGCGGTGTGGCAATCAGTGCGGTAGTGCTACGTGATTTACCTGTGCATG
AGTACGCTGCTAGGCAAATCAAACTGGCTGTGGTTGGTCGCGGTGGTGCCGACAAGCAACAGATCCAGCATATGGTTGGT
GTCATGCTGAATCTGCAAGGTAGGTTACAGTCTGATGCAGCAGATGCATTGGCGGTCGCTATTACGCATGCTCATGTGAG
TGCTACTGCTCAGCGCTTAGGCGTCAGTACGAAGCAGGCGTGGAGCCGGAAATGA

Upstream 100 bases:

>100_bases
ATATACTGGAAGACTTGGATGATGTTCAGGACGTGTATTCCAACGTTGATCAAGTGACGTTGGGCAAGCGTTGAGATGAA
TACTTACAAGATCCATCGCA

Downstream 100 bases:

>100_bases
TTAAAGGCCTGTGGGTGGTTTGGGGTCTCCTCATTAGAGCGGCGACCTGTGATGAGCATACGGCTTTTTGTAAAGAGCAT
CACGTATGATTGGTCGCTTG

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MLIAMDTLHLCLNCSSIIDHFVLMCSRIAYQMTRILGIDPGSQRTGVGVIDVDEYGCSHHVYHAPLVLLGQSSFAGRLKQ
LLLGLSAVIEEYSPKEVAIEKVFMSKNADSALKLGQARGVAISAVVLRDLPVHEYAARQIKLAVVGRGGADKQQIQHMVG
VMLNLQGRLQSDAADALAVAITHAHVSATAQRLGVSTKQAWSRK

Sequences:

>Translated_204_residues
MLIAMDTLHLCLNCSSIIDHFVLMCSRIAYQMTRILGIDPGSQRTGVGVIDVDEYGCSHHVYHAPLVLLGQSSFAGRLKQ
LLLGLSAVIEEYSPKEVAIEKVFMSKNADSALKLGQARGVAISAVVLRDLPVHEYAARQIKLAVVGRGGADKQQIQHMVG
VMLNLQGRLQSDAADALAVAITHAHVSATAQRLGVSTKQAWSRK
>Mature_204_residues
MLIAMDTLHLCLNCSSIIDHFVLMCSRIAYQMTRILGIDPGSQRTGVGVIDVDEYGCSHHVYHAPLVLLGQSSFAGRLKQ
LLLGLSAVIEEYSPKEVAIEKVFMSKNADSALKLGQARGVAISAVVLRDLPVHEYAARQIKLAVVGRGGADKQQIQHMVG
VMLNLQGRLQSDAADALAVAITHAHVSATAQRLGVSTKQAWSRK

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=165, Percent_Identity=52.1212121212121, Blast_Score=133, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 22009; Mature: 22009

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIAMDTLHLCLNCSSIIDHFVLMCSRIAYQMTRILGIDPGSQRTGVGVIDVDEYGCSHH
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCC
VYHAPLVLLGQSSFAGRLKQLLLGLSAVIEEYSPKEVAIEKVFMSKNADSALKLGQARGV
HHHCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHCCCCH
AISAVVLRDLPVHEYAARQIKLAVVGRGGADKQQIQHMVGVMLNLQGRLQSDAADALAVA
HHHHHHHHCCCHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ITHAHVSATAQRLGVSTKQAWSRK
HHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MLIAMDTLHLCLNCSSIIDHFVLMCSRIAYQMTRILGIDPGSQRTGVGVIDVDEYGCSHH
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCC
VYHAPLVLLGQSSFAGRLKQLLLGLSAVIEEYSPKEVAIEKVFMSKNADSALKLGQARGV
HHHCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHCCCCH
AISAVVLRDLPVHEYAARQIKLAVVGRGGADKQQIQHMVGVMLNLQGRLQSDAADALAVA
HHHHHHHHCCCHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ITHAHVSATAQRLGVSTKQAWSRK
HHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]