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The map label for this gene is nadA [H]

Identifier: 182681470

GI number: 182681470

Start: 1090935

End: 1091906

Strand: Reverse

Name: nadA [H]

Synonym: XfasM23_0922

Alternate gene names: 182681470

Gene position: 1091906-1090935 (Counterclockwise)

Preceding gene: 182681471

Following gene: 182681469

Centisome position: 43.06

GC content: 49.59

Gene sequence:

>972_bases
GTGAACCACGCCGTTTTATCTTCGTGTATCGATAAATGCGGCGACTGTTTCGCCTCAGAAGCAGCGCGTATAAAGTTTGA
CAATGACATTGAGGCGATCTTCGAACTCAAACGCAAACGAAACGCTGTCATTCTTGCGCATAATTACCAAACTCCAGAGA
TCTTTCATGGTGTTGCCGACATTGTGGGTGACAGCCTCGCATTAGCCCGTAAAGCAATTGATGTCGATGCCGATGTGATC
GTCCTTGCCGGAGTGCATTTCATGGCAGAGACCGCAAAACTGCTGAATCCAGAAAAAACCGTATTGATCCCCGATAGGGA
GGCAGGTTGCTCTTTAGCGGAGTCGATTACACCGGAAGACGTAGCCTTATTACGTCAGGCGCATCCTGGCATTCCTATTG
TCACCTATGTGAATACTTCAGCAGCCGTAAAAGCGGCTTCAGATATCTGCTGCACCTCAGGTAATGCCAAAAAGGTGGTG
GAAGCACTTGGTGTTCCCAAAGTTCTGATGATTCCAGACGAATATTTAGCACGCAATGTTGCCAAAGAAACGGAAGTCCA
GATCATTTCATGGCATGGCCATTGCGAAGTCCATGAACTTTTCTCAGCCAGCGATATCTTGCAGCTTCGCGAAAATCATC
CAGGTGTCACCGTACTCGCCCATCCCGAATGTCCGCCGGATGTGGTGGCAGCAGCAGATTTTGCAGGCTCCACAGCAGCG
ATGTCCGACTATGTCACTACTAAGCAGCCCAAGCGAGTCGTACTTCTCACAGAATGCTCAATGAGCGATAACATCGCCGT
CCATCATCCAGATGTTGAGTTCATCAGCTCCTGCAATCTTTGCCCGCACATGAAACGGATCACGCTTGCCAATATCCGAA
CCGCCTTGGAAGAAAACCGTCACGAAGTCACGGTAGATGCAAAAATTGCAGACCCCGCACGACGCGCCGTTGAAAGGATG
TTGGCGATATGA

Upstream 100 bases:

>100_bases
TTAGCCTCACGTTGATGCATACATAACGTCAGAAGCAAGTCATATCGACTTCTTGGAAGAAGCGCATAATATGCGTGAAA
TTAGCATAAGGGAGATCGTA

Downstream 100 bases:

>100_bases
CCAACGAGCAAGATGGCTAAGATAGTGGACTGTTTTGCAGACCGCCCCATCATCGTTGGTAGCGGGCTTGCTGGTCTGAT
CGCAGCACTGACCATTTCTC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MNHAVLSSCIDKCGDCFASEAARIKFDNDIEAIFELKRKRNAVILAHNYQTPEIFHGVADIVGDSLALARKAIDVDADVI
VLAGVHFMAETAKLLNPEKTVLIPDREAGCSLAESITPEDVALLRQAHPGIPIVTYVNTSAAVKAASDICCTSGNAKKVV
EALGVPKVLMIPDEYLARNVAKETEVQIISWHGHCEVHELFSASDILQLRENHPGVTVLAHPECPPDVVAAADFAGSTAA
MSDYVTTKQPKRVVLLTECSMSDNIAVHHPDVEFISSCNLCPHMKRITLANIRTALEENRHEVTVDAKIADPARRAVERM
LAI

Sequences:

>Translated_323_residues
MNHAVLSSCIDKCGDCFASEAARIKFDNDIEAIFELKRKRNAVILAHNYQTPEIFHGVADIVGDSLALARKAIDVDADVI
VLAGVHFMAETAKLLNPEKTVLIPDREAGCSLAESITPEDVALLRQAHPGIPIVTYVNTSAAVKAASDICCTSGNAKKVV
EALGVPKVLMIPDEYLARNVAKETEVQIISWHGHCEVHELFSASDILQLRENHPGVTVLAHPECPPDVVAAADFAGSTAA
MSDYVTTKQPKRVVLLTECSMSDNIAVHHPDVEFISSCNLCPHMKRITLANIRTALEENRHEVTVDAKIADPARRAVERM
LAI
>Mature_323_residues
MNHAVLSSCIDKCGDCFASEAARIKFDNDIEAIFELKRKRNAVILAHNYQTPEIFHGVADIVGDSLALARKAIDVDADVI
VLAGVHFMAETAKLLNPEKTVLIPDREAGCSLAESITPEDVALLRQAHPGIPIVTYVNTSAAVKAASDICCTSGNAKKVV
EALGVPKVLMIPDEYLARNVAKETEVQIISWHGHCEVHELFSASDILQLRENHPGVTVLAHPECPPDVVAAADFAGSTAA
MSDYVTTKQPKRVVLLTECSMSDNIAVHHPDVEFISSCNLCPHMKRITLANIRTALEENRHEVTVDAKIADPARRAVERM
LAI

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=310, Percent_Identity=36.7741935483871, Blast_Score=174, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 35052; Mature: 35052

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHAVLSSCIDKCGDCFASEAARIKFDNDIEAIFELKRKRNAVILAHNYQTPEIFHGVAD
CCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
IVGDSLALARKAIDVDADVIVLAGVHFMAETAKLLNPEKTVLIPDREAGCSLAESITPED
HHCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHCCCHHH
VALLRQAHPGIPIVTYVNTSAAVKAASDICCTSGNAKKVVEALGVPKVLMIPDEYLARNV
HHHHHHCCCCCCEEEEECCHHHHHHHHHHEECCCCHHHHHHHHCCCEEEECCHHHHHHHH
AKETEVQIISWHGHCEVHELFSASDILQLRENHPGVTVLAHPECPPDVVAAADFAGSTAA
CCCCCEEEEEECCCCHHHHHHCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCCCHHH
MSDYVTTKQPKRVVLLTECSMSDNIAVHHPDVEFISSCNLCPHMKRITLANIRTALEENR
HHHHHCCCCCCEEEEEEECCCCCCEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
HEVTVDAKIADPARRAVERMLAI
CEEEEEEEECCHHHHHHHHHHCC
>Mature Secondary Structure
MNHAVLSSCIDKCGDCFASEAARIKFDNDIEAIFELKRKRNAVILAHNYQTPEIFHGVAD
CCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
IVGDSLALARKAIDVDADVIVLAGVHFMAETAKLLNPEKTVLIPDREAGCSLAESITPED
HHCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHCCCHHH
VALLRQAHPGIPIVTYVNTSAAVKAASDICCTSGNAKKVVEALGVPKVLMIPDEYLARNV
HHHHHHCCCCCCEEEEECCHHHHHHHHHHEECCCCHHHHHHHHCCCEEEECCHHHHHHHH
AKETEVQIISWHGHCEVHELFSASDILQLRENHPGVTVLAHPECPPDVVAAADFAGSTAA
CCCCCEEEEEECCCCHHHHHHCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCCCHHH
MSDYVTTKQPKRVVLLTECSMSDNIAVHHPDVEFISSCNLCPHMKRITLANIRTALEENR
HHHHHCCCCCCEEEEEEECCCCCCEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
HEVTVDAKIADPARRAVERMLAI
CEEEEEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]