| Definition | Xylella fastidiosa M23 chromosome, complete genome. |
|---|---|
| Accession | NC_010577 |
| Length | 2,535,690 |
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The map label for this gene is clpA [H]
Identifier: 182681254
GI number: 182681254
Start: 823308
End: 825584
Strand: Direct
Name: clpA [H]
Synonym: XfasM23_0699
Alternate gene names: 182681254
Gene position: 823308-825584 (Clockwise)
Preceding gene: 182681253
Following gene: 182681259
Centisome position: 32.47
GC content: 50.9
Gene sequence:
>2277_bases ATGTTCAGCAAAGATCTCGAGCAAACAATAGGCCAGTGCTACAAGCGAACGCGTGAGGCGTGTCATGAGTTCATGACCGT TGAGCATCTGCTTCTTTCATTGTTGGACAATCCATTGGCGCACGCTGTACTGAAGGCTTGCGGAGCGGATGTTACCAGGC TGAAGCGTGACCTTGAGCAGGCCATTGAGGTATCTATTACCCGCTTGGATGCCGATGACGGCCGTGATACTCAGCCGACG CTTGGTTTCCAGCGAGTGCTGCAGCGTGCTGTTTACCATGTGCAGTCTTCTGGTAAGAAGGAGGTGACCGGCGCTAATGT ACTGGTGGCTATCTTTGGTGAAAAGGATTCGCATGCCGTCTACTTTCTGAATCAGCAGGACATCAGCCGACTCGATATCG TCAACTATTTATCCCACGGTATTACCCGTATGGGCGAGGAGAGTGACATCGGGCAAGCTGCTGAGAATGAGGCTAAGGGG GAAAGTGAGGCGAATAAGGGGGATGCTCTTGCTGAATATGCTATTAACTTGAATGAGCATGCACGGAATGGACGAATTGA TCCATTGGTTGGGCGCAAAGATGAGATTGAACGTACGATCCAGGTGTTATGCCGACGTCGCAAGAATAACCCGCTCTATG TAGGTGAAGCGGGCGTTGGTAAAACCGCAATCGCTGAGGGTTTGGCCAAGCGTATTGTTGATCGTAGTGTGCCGGAGGTG CTTGCCGATGCGGTGATCTACTCGTTGGATCTTGGCGCTCTGGTGGCTGGTACCAAATATCGTGGTGACTTTGAAAAACG TCTGAAGGGTGTGTTAAGTGCGTTGCGCAAAACCCCTAACGTAGTTTTGTTTATTGATGAAATCCATACCATCATCGGCG CTGGTTCCGCTTCGGGTGGCACGATGGATGCGTCTAATTTGATCAAGCCAGCCTTGGCTTCAGGTGAGTTACGTTGCATT GGTTCGACCACGTTTCAAGAGTATCGCGGCATCTTCGAAAAGGACCGTGCTTTGGCGAGGCGTTTTCAGAAGATCGATAT CGTCGAGCCTACCGCGGGCGAGGCTTTCGAGATTCTACAAGGACTCAAGCCTAAGTATGAGGCACATCACGGCGTTACCT ATGCTGATGACGCATTGCGCGCTGCGGTTGATTTATCGGTCAAGCACATCGGTGATCGGTTGTTGCCGGATAAGGCGATT GATGTGATAGATGAGGCGGGCGCGCGTCAGCGCCTGTTGCCGGAGAAAGAACGCAAAGAGCTGATCGATATTGAGGAGAT TGAGACCATTGTTACGAAGATGGCTAGGGTCCCGGCGAAGCAGGTGAGTGTGAGCGATAAGGACGTTTTGAAGCACCTCG AACGCAATTTGAAGATGGTGATCTTTGGTCAGGAGCCAGCGATTGAGATGCTGTCGTCGGCAATTAAGTTGGCGCGCAGT GGCCTAGGTAATCCGGATAAGCCGATTGGAAACTTCCTGCTTGCTGGCCCAACGGGGGTTGGTAAAACTGAGGTGACTAA ACAATTAGCACACCATCTTGGGATCGAGTTGGTACGTTTTGACATGTCTGAGTACATGGAGCCGCATTCGGTGAGTCGTC TGATTGGTGCGCCTCCGGGCTATGTTGGTTTTGATCAGGGAGGGTTGCTGACTGAGAAGATCGTCAAGACTCCACACTGC GTTCTGCTGTTGGACGAGGTGGAGAAAGCGCATATGGATGTCTTCAATATTCTCCTACAGGTCATGGATCGCGGTGTGTT AACGGATACCAATGGACGTGAGGCGAGTTTTAAAAATGTGATCCTGGTAATGACGACCAATGCAGGTGCGTCCCAATCTT CACGGCGTACGATTGGTTTCACTAAGCAGGACCATACCAGCGATGCGATGGAAGTGATTTGTCGCAGCTTCAGCCCTGAG TTCCGCAATCGTCTTGATGCGATTGTGCAGTTTCAGCCACTGGGTTTCAGTCACATTCTGCGGGTTGTCGACAAGTTCAT CATTGAGTTGGAGATGTTACTTCAAGAGAAGCGTGTTGTTTTGTCGGCTACGCCGATTGCTCGCGACTGGCTGGCTCAGC ATGGTTTTGATCCGCTTATGGGTGCTCGTCCGATGGCACGTGTGATTCAAGAGAAAATCAAACGCCCACTTGCAGACGAA TTGTTGTTTGGTAAGTTGCTCAACGGTGGTCGGGTAGGCATTGATGTGCGTGATAATGAGTTAATTGTTGAGACTTATTC GGAACCAGAGCTGTTGTTTCCGGCGACCGTGGAGTAA
Upstream 100 bases:
>100_bases AGTCGGCCCTAACGGTGTCTGAATGCTTTGATTTAGCAGGGCTGTGGAAAATCCCCGCTCATGCCTCATATTGTGTGTAA CAGTTGTTGGAGTCACTCAT
Downstream 100 bases:
>100_bases TGGTGATGTGTTGCTTCACTTAAGGTTGTTAGAGTGATCTTTAGTCTCTGTGTTCAGTCATGCTTGAAGCTAGCCAGTCT GTTATTGCATGGCTGTATAA
Product: ATP-dependent Clp protease, ATP-binding subunit clpA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 758; Mature: 758
Protein sequence:
>758_residues MFSKDLEQTIGQCYKRTREACHEFMTVEHLLLSLLDNPLAHAVLKACGADVTRLKRDLEQAIEVSITRLDADDGRDTQPT LGFQRVLQRAVYHVQSSGKKEVTGANVLVAIFGEKDSHAVYFLNQQDISRLDIVNYLSHGITRMGEESDIGQAAENEAKG ESEANKGDALAEYAINLNEHARNGRIDPLVGRKDEIERTIQVLCRRRKNNPLYVGEAGVGKTAIAEGLAKRIVDRSVPEV LADAVIYSLDLGALVAGTKYRGDFEKRLKGVLSALRKTPNVVLFIDEIHTIIGAGSASGGTMDASNLIKPALASGELRCI GSTTFQEYRGIFEKDRALARRFQKIDIVEPTAGEAFEILQGLKPKYEAHHGVTYADDALRAAVDLSVKHIGDRLLPDKAI DVIDEAGARQRLLPEKERKELIDIEEIETIVTKMARVPAKQVSVSDKDVLKHLERNLKMVIFGQEPAIEMLSSAIKLARS GLGNPDKPIGNFLLAGPTGVGKTEVTKQLAHHLGIELVRFDMSEYMEPHSVSRLIGAPPGYVGFDQGGLLTEKIVKTPHC VLLLDEVEKAHMDVFNILLQVMDRGVLTDTNGREASFKNVILVMTTNAGASQSSRRTIGFTKQDHTSDAMEVICRSFSPE FRNRLDAIVQFQPLGFSHILRVVDKFIIELEMLLQEKRVVLSATPIARDWLAQHGFDPLMGARPMARVIQEKIKRPLADE LLFGKLLNGGRVGIDVRDNELIVETYSEPELLFPATVE
Sequences:
>Translated_758_residues MFSKDLEQTIGQCYKRTREACHEFMTVEHLLLSLLDNPLAHAVLKACGADVTRLKRDLEQAIEVSITRLDADDGRDTQPT LGFQRVLQRAVYHVQSSGKKEVTGANVLVAIFGEKDSHAVYFLNQQDISRLDIVNYLSHGITRMGEESDIGQAAENEAKG ESEANKGDALAEYAINLNEHARNGRIDPLVGRKDEIERTIQVLCRRRKNNPLYVGEAGVGKTAIAEGLAKRIVDRSVPEV LADAVIYSLDLGALVAGTKYRGDFEKRLKGVLSALRKTPNVVLFIDEIHTIIGAGSASGGTMDASNLIKPALASGELRCI GSTTFQEYRGIFEKDRALARRFQKIDIVEPTAGEAFEILQGLKPKYEAHHGVTYADDALRAAVDLSVKHIGDRLLPDKAI DVIDEAGARQRLLPEKERKELIDIEEIETIVTKMARVPAKQVSVSDKDVLKHLERNLKMVIFGQEPAIEMLSSAIKLARS GLGNPDKPIGNFLLAGPTGVGKTEVTKQLAHHLGIELVRFDMSEYMEPHSVSRLIGAPPGYVGFDQGGLLTEKIVKTPHC VLLLDEVEKAHMDVFNILLQVMDRGVLTDTNGREASFKNVILVMTTNAGASQSSRRTIGFTKQDHTSDAMEVICRSFSPE FRNRLDAIVQFQPLGFSHILRVVDKFIIELEMLLQEKRVVLSATPIARDWLAQHGFDPLMGARPMARVIQEKIKRPLADE LLFGKLLNGGRVGIDVRDNELIVETYSEPELLFPATVE >Mature_758_residues MFSKDLEQTIGQCYKRTREACHEFMTVEHLLLSLLDNPLAHAVLKACGADVTRLKRDLEQAIEVSITRLDADDGRDTQPT LGFQRVLQRAVYHVQSSGKKEVTGANVLVAIFGEKDSHAVYFLNQQDISRLDIVNYLSHGITRMGEESDIGQAAENEAKG ESEANKGDALAEYAINLNEHARNGRIDPLVGRKDEIERTIQVLCRRRKNNPLYVGEAGVGKTAIAEGLAKRIVDRSVPEV LADAVIYSLDLGALVAGTKYRGDFEKRLKGVLSALRKTPNVVLFIDEIHTIIGAGSASGGTMDASNLIKPALASGELRCI GSTTFQEYRGIFEKDRALARRFQKIDIVEPTAGEAFEILQGLKPKYEAHHGVTYADDALRAAVDLSVKHIGDRLLPDKAI DVIDEAGARQRLLPEKERKELIDIEEIETIVTKMARVPAKQVSVSDKDVLKHLERNLKMVIFGQEPAIEMLSSAIKLARS GLGNPDKPIGNFLLAGPTGVGKTEVTKQLAHHLGIELVRFDMSEYMEPHSVSRLIGAPPGYVGFDQGGLLTEKIVKTPHC VLLLDEVEKAHMDVFNILLQVMDRGVLTDTNGREASFKNVILVMTTNAGASQSSRRTIGFTKQDHTSDAMEVICRSFSPE FRNRLDAIVQFQPLGFSHILRVVDKFIIELEMLLQEKRVVLSATPIARDWLAQHGFDPLMGARPMARVIQEKIKRPLADE LLFGKLLNGGRVGIDVRDNELIVETYSEPELLFPATVE
Specific function: ATP-dependent specificity component of the ClpP protease. It directs the protease to specific substrates. The primary function of the ClpA-ClpP complex appears to be the degradation of unfolded or abnormal proteins [H]
COG id: COG0542
COG function: function code O; ATPases with chaperone activity, ATP-binding subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the clpA/clpB family [H]
Homologues:
Organism=Homo sapiens, GI13540606, Length=341, Percent_Identity=31.0850439882698, Blast_Score=149, Evalue=1e-35, Organism=Escherichia coli, GI1787109, Length=747, Percent_Identity=62.1151271753681, Blast_Score=941, Evalue=0.0, Organism=Escherichia coli, GI1788943, Length=410, Percent_Identity=44.1463414634146, Blast_Score=299, Evalue=5e-82, Organism=Saccharomyces cerevisiae, GI6323002, Length=327, Percent_Identity=42.2018348623853, Blast_Score=262, Evalue=2e-70, Organism=Saccharomyces cerevisiae, GI6320464, Length=317, Percent_Identity=46.6876971608833, Blast_Score=259, Evalue=9e-70,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR013093 - InterPro: IPR003959 - InterPro: IPR018368 - InterPro: IPR001270 - InterPro: IPR019489 - InterPro: IPR004176 - InterPro: IPR013461 - InterPro: IPR023150 [H]
Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]
EC number: NA
Molecular weight: Translated: 83833; Mature: 83833
Theoretical pI: Translated: 6.36; Mature: 6.36
Prosite motif: PS00870 CLPAB_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFSKDLEQTIGQCYKRTREACHEFMTVEHLLLSLLDNPLAHAVLKACGADVTRLKRDLEQ CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHH AIEVSITRLDADDGRDTQPTLGFQRVLQRAVYHVQSSGKKEVTGANVLVAIFGEKDSHAV HHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEE YFLNQQDISRLDIVNYLSHGITRMGEESDIGQAAENEAKGESEANKGDALAEYAINLNEH EEECHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCHHH ARNGRIDPLVGRKDEIERTIQVLCRRRKNNPLYVGEAGVGKTAIAEGLAKRIVDRSVPEV CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH LADAVIYSLDLGALVAGTKYRGDFEKRLKGVLSALRKTPNVVLFIDEIHTIIGAGSASGG HHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCC TMDASNLIKPALASGELRCIGSTTFQEYRGIFEKDRALARRFQKIDIVEPTAGEAFEILQ CCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH GLKPKYEAHHGVTYADDALRAAVDLSVKHIGDRLLPDKAIDVIDEAGARQRLLPEKERKE CCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHCCCCHHHHH LIDIEEIETIVTKMARVPAKQVSVSDKDVLKHLERNLKMVIFGQEPAIEMLSSAIKLARS CCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHH GLGNPDKPIGNFLLAGPTGVGKTEVTKQLAHHLGIELVRFDMSEYMEPHSVSRLIGAPPG CCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCHHHEEECHHHHCCHHHHHHHHCCCCC YVGFDQGGLLTEKIVKTPHCVLLLDEVEKAHMDVFNILLQVMDRGVLTDTNGREASFKNV CCCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCE ILVMTTNAGASQSSRRTIGFTKQDHTSDAMEVICRSFSPEFRNRLDAIVQFQPLGFSHIL EEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHEECCCCHHHHH RVVDKFIIELEMLLQEKRVVLSATPIARDWLAQHGFDPLMGARPMARVIQEKIKRPLADE HHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHH LLFGKLLNGGRVGIDVRDNELIVETYSEPELLFPATVE HHHHHHCCCCEEEEEECCCEEEEEECCCCCEECCCCCC >Mature Secondary Structure MFSKDLEQTIGQCYKRTREACHEFMTVEHLLLSLLDNPLAHAVLKACGADVTRLKRDLEQ CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHH AIEVSITRLDADDGRDTQPTLGFQRVLQRAVYHVQSSGKKEVTGANVLVAIFGEKDSHAV HHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEE YFLNQQDISRLDIVNYLSHGITRMGEESDIGQAAENEAKGESEANKGDALAEYAINLNEH EEECHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCHHH ARNGRIDPLVGRKDEIERTIQVLCRRRKNNPLYVGEAGVGKTAIAEGLAKRIVDRSVPEV CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH LADAVIYSLDLGALVAGTKYRGDFEKRLKGVLSALRKTPNVVLFIDEIHTIIGAGSASGG HHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCC TMDASNLIKPALASGELRCIGSTTFQEYRGIFEKDRALARRFQKIDIVEPTAGEAFEILQ CCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH GLKPKYEAHHGVTYADDALRAAVDLSVKHIGDRLLPDKAIDVIDEAGARQRLLPEKERKE CCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHCCCCHHHHH LIDIEEIETIVTKMARVPAKQVSVSDKDVLKHLERNLKMVIFGQEPAIEMLSSAIKLARS CCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHH GLGNPDKPIGNFLLAGPTGVGKTEVTKQLAHHLGIELVRFDMSEYMEPHSVSRLIGAPPG CCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCHHHEEECHHHHCCHHHHHHHHCCCCC YVGFDQGGLLTEKIVKTPHCVLLLDEVEKAHMDVFNILLQVMDRGVLTDTNGREASFKNV CCCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCE ILVMTTNAGASQSSRRTIGFTKQDHTSDAMEVICRSFSPEFRNRLDAIVQFQPLGFSHIL EEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHEECCCCHHHHH RVVDKFIIELEMLLQEKRVVLSATPIARDWLAQHGFDPLMGARPMARVIQEKIKRPLADE HHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHH LLFGKLLNGGRVGIDVRDNELIVETYSEPELLFPATVE HHHHHHCCCCEEEEEECCCEEEEEECCCCCEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]