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The map label for this gene is ftsK [H]

Identifier: 182681259

GI number: 182681259

Start: 829809

End: 832163

Strand: Direct

Name: ftsK [H]

Synonym: XfasM23_0704

Alternate gene names: 182681259

Gene position: 829809-832163 (Clockwise)

Preceding gene: 182681254

Following gene: 182681260

Centisome position: 32.73

GC content: 52.78

Gene sequence:

>2355_bases
GTGGCAAAACAAGTTCCCGAGCGCAGCAAACCCAACGCGGGTAAGCCTTCCATACGCAAGGTATGGAGTGTGAATGGCCA
TAGACTGAAGCAACATAAGCTTTTGCGGGATCTGGTGTTGATCATGATCGCACCGGTATTGGTATACCTCATGGCGAGTT
TGTTTACCTACTCCAAAGATGATCCGGGTTGGTCCCAGAGCGGTAGCGCAATTGTGCACAACATCGGTGGAAAGGCAGGT
GCTTGGATTGCGGATGTGCTGTTCCAGCTCTGTGGCTTCGTTGCTTTTTTGCTGCCAGTGGCATTGGGTGTTGTTAGTTG
GATTGCCCTGTTTGGCAGTGACCAAGAGGAGCAAGCGGAAGGACATTTGGAGCCAGCGCTCCGTTTGGTGGGTATCGTCG
GTTTTTTGATTGCAGCGACAGGTTTATTTCATCTGCACTTGTTTCAGAGCGATGTGGCGCGCGCTGGCGGCATTCTTGGT
AAACAGGTGTGCAATTCACTACAAGCGGGTTTTGGTGTCTTCGGTACTAACTTATTTGTCCTGATGTTGCTGTTAATTTC
GGTGACGTTGGCCACCGGTTTGTCTTGGTTTGCATTGATGGAGCGCATTGGTCGCGTTGTGCTTGCAGTTCCACCGCTGC
TGCAGAAGAGCAAGCGCCGCGCCGACGAATGGCAGCATGCGCGTGCCTTGCGTGAGGAGCGTGAGGAAGTCCGCAAAATT
GATGCGGTACAGCGTGCCAAACGCGATCCGATGAAGATCGAATTACCTCCTGAGCCGATAGTGGAGAAGAGCGAGCGTGC
CAAGCGTGATACGCAGATCCCCATGTTCCTTGGGGTGAACAAGCGTGGTTCTGACTTGCCGTCATTGGCGTTGTTAGATA
ATCCTAAGCCGCAGATCAAAGGCTACTCTGATGAAACATTGGAGGCGCTATCCCGTCAGATTGAGTTGAAGTTCAAGGAT
TTTCGTATTGATGTACAGGTGGTGGGTGCCTATCCGGGACCAGTGATTACTCGCTTTGAGATTGAGCCAGCACGCGGCGT
GAAGGTGAGCCAGATCAGCGCGTTGGATAAAGACATTGCGCGCGGCTTATCGGTCAAATCGGTACGCGTGGTTGAAGTGA
TTCCAGGGAAGTCAGTGATTGGATTGGAGATCCCTAACGTCAACCGCGAAATGATCTTTCTATCCGAACTCCTACGTTCC
AAGGAGTACGACAAGTCGCCGAGTTCATTGACTCTGGCGCTGGGTAAGAATATTGCTGGTCGGCCGACAGTTGCTGACTT
GGCACGGATGCCGCACCTGTTGGTTGCCGGCACTACGGGTTCAGGGAAGTCAGTGGCTGTTAATGCAATGGTGTTGAGCC
TGTTGTTCAAAGCCTCACACAATGATCTTCGGATGCTGATGATCGATCCCAAGATGCTTGAATTGAGCGTCTACCAAGGC
ATTCCACACCTGCTGGCGCCCGTAGTGACTGACATGAAGGAGGCTGCGAACGGTTTGCGTTGGTGTGTGGCTGAGATGGA
ACGCCGTTATAAGTTGATGAGTGCGGTTGGCGTACGCAATTTGGCCGGTTTCAACAAGAAGGTGAAGGATGCTGAAGAGG
CTGGTCAGCCATTGATGGACCCGCTTTTTAAGCCGAACCCTGACCTGAGCGAGGTGCCGCGGCCACTGCAAAAATTGCCG
TTTATTGTCATCTTCATTGATGAATTTGCCGACATGATGATGATTGTCGGCAAGAAGGTTGAGGAATTGATCGCACGCTT
AGCGCAGAAAGCGCGTGCAGCTGGTATCCACCTGATTCTTGCCACTCAGCGTCCCTCGGTGGATGTGATCACTGGACTGA
TTAAGGCTAACATTCCGACGCGTATCGCGTTTCAAGTCAGCTCGAAGATTGACTCACGTACGATCCTGGATCAGTCCGGC
GCTGAAACTTTATTGGGCCACGGCGACATGCTGTATTTACCTCCTGGTACAGCAATGCCGGAGCGCGTGCATGGTGCTTT
TGTCAGCGATGATGAAGTACATCGTGTTGTTGAGTACTTGAAGGCTAGTGCTCCAGTCCAATATGTGGATGGGGTGCTTG
ATGAGATTCAAACCATGGATGATGGTGTCGTGATCGGTCCTGCTGGATTTCCGGAGAGTGCCAGTGGTGGCGGTGATGAG
ACCGATCCTTTGTACGATGAAGCCTTACGTATTGTGACCGAGACGCGCCGTGCTTCCATCTCCAGTGTGCAGCGGCGGCT
GAGGATTGGTTACAACCGAGCCGCGCGTTTGATCGAAGCTATGGAAACAGCGGGCGTGGTCAGTCCGCCCGAGCACAACG
GTGATCGCGCCGTGTTGGCTCCACCACCGCGCTAA

Upstream 100 bases:

>100_bases
GACTATACCCGGTTCTTCATCGATATGAGTGCAGCTGAAACCAAGTTCAATGTCATTTATTATCAATTACTAATGCAGCA
CTCCTAAGGTTTAGTAACAA

Downstream 100 bases:

>100_bases
GGGGTCTCACAACAGGTAAGCAAGTAACGGGGCTCACAACAAGTTAGCTCATGCTCACCTGTGTTCCTGTTAAATCAGGT
GCTTGTGTCACCCTTCGCGA

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 784; Mature: 783

Protein sequence:

>784_residues
MAKQVPERSKPNAGKPSIRKVWSVNGHRLKQHKLLRDLVLIMIAPVLVYLMASLFTYSKDDPGWSQSGSAIVHNIGGKAG
AWIADVLFQLCGFVAFLLPVALGVVSWIALFGSDQEEQAEGHLEPALRLVGIVGFLIAATGLFHLHLFQSDVARAGGILG
KQVCNSLQAGFGVFGTNLFVLMLLLISVTLATGLSWFALMERIGRVVLAVPPLLQKSKRRADEWQHARALREEREEVRKI
DAVQRAKRDPMKIELPPEPIVEKSERAKRDTQIPMFLGVNKRGSDLPSLALLDNPKPQIKGYSDETLEALSRQIELKFKD
FRIDVQVVGAYPGPVITRFEIEPARGVKVSQISALDKDIARGLSVKSVRVVEVIPGKSVIGLEIPNVNREMIFLSELLRS
KEYDKSPSSLTLALGKNIAGRPTVADLARMPHLLVAGTTGSGKSVAVNAMVLSLLFKASHNDLRMLMIDPKMLELSVYQG
IPHLLAPVVTDMKEAANGLRWCVAEMERRYKLMSAVGVRNLAGFNKKVKDAEEAGQPLMDPLFKPNPDLSEVPRPLQKLP
FIVIFIDEFADMMMIVGKKVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQSG
AETLLGHGDMLYLPPGTAMPERVHGAFVSDDEVHRVVEYLKASAPVQYVDGVLDEIQTMDDGVVIGPAGFPESASGGGDE
TDPLYDEALRIVTETRRASISSVQRRLRIGYNRAARLIEAMETAGVVSPPEHNGDRAVLAPPPR

Sequences:

>Translated_784_residues
MAKQVPERSKPNAGKPSIRKVWSVNGHRLKQHKLLRDLVLIMIAPVLVYLMASLFTYSKDDPGWSQSGSAIVHNIGGKAG
AWIADVLFQLCGFVAFLLPVALGVVSWIALFGSDQEEQAEGHLEPALRLVGIVGFLIAATGLFHLHLFQSDVARAGGILG
KQVCNSLQAGFGVFGTNLFVLMLLLISVTLATGLSWFALMERIGRVVLAVPPLLQKSKRRADEWQHARALREEREEVRKI
DAVQRAKRDPMKIELPPEPIVEKSERAKRDTQIPMFLGVNKRGSDLPSLALLDNPKPQIKGYSDETLEALSRQIELKFKD
FRIDVQVVGAYPGPVITRFEIEPARGVKVSQISALDKDIARGLSVKSVRVVEVIPGKSVIGLEIPNVNREMIFLSELLRS
KEYDKSPSSLTLALGKNIAGRPTVADLARMPHLLVAGTTGSGKSVAVNAMVLSLLFKASHNDLRMLMIDPKMLELSVYQG
IPHLLAPVVTDMKEAANGLRWCVAEMERRYKLMSAVGVRNLAGFNKKVKDAEEAGQPLMDPLFKPNPDLSEVPRPLQKLP
FIVIFIDEFADMMMIVGKKVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQSG
AETLLGHGDMLYLPPGTAMPERVHGAFVSDDEVHRVVEYLKASAPVQYVDGVLDEIQTMDDGVVIGPAGFPESASGGGDE
TDPLYDEALRIVTETRRASISSVQRRLRIGYNRAARLIEAMETAGVVSPPEHNGDRAVLAPPPR
>Mature_783_residues
AKQVPERSKPNAGKPSIRKVWSVNGHRLKQHKLLRDLVLIMIAPVLVYLMASLFTYSKDDPGWSQSGSAIVHNIGGKAGA
WIADVLFQLCGFVAFLLPVALGVVSWIALFGSDQEEQAEGHLEPALRLVGIVGFLIAATGLFHLHLFQSDVARAGGILGK
QVCNSLQAGFGVFGTNLFVLMLLLISVTLATGLSWFALMERIGRVVLAVPPLLQKSKRRADEWQHARALREEREEVRKID
AVQRAKRDPMKIELPPEPIVEKSERAKRDTQIPMFLGVNKRGSDLPSLALLDNPKPQIKGYSDETLEALSRQIELKFKDF
RIDVQVVGAYPGPVITRFEIEPARGVKVSQISALDKDIARGLSVKSVRVVEVIPGKSVIGLEIPNVNREMIFLSELLRSK
EYDKSPSSLTLALGKNIAGRPTVADLARMPHLLVAGTTGSGKSVAVNAMVLSLLFKASHNDLRMLMIDPKMLELSVYQGI
PHLLAPVVTDMKEAANGLRWCVAEMERRYKLMSAVGVRNLAGFNKKVKDAEEAGQPLMDPLFKPNPDLSEVPRPLQKLPF
IVIFIDEFADMMMIVGKKVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQSGA
ETLLGHGDMLYLPPGTAMPERVHGAFVSDDEVHRVVEYLKASAPVQYVDGVLDEIQTMDDGVVIGPAGFPESASGGGDET
DPLYDEALRIVTETRRASISSVQRRLRIGYNRAARLIEAMETAGVVSPPEHNGDRAVLAPPPR

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=505, Percent_Identity=62.1782178217822, Blast_Score=615, Evalue=1e-177,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 85858; Mature: 85727

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCC
>Mature Secondary Structure 
AKQVPERSKPNAGKPSIRKVWSVNGHRLKQHKLLRDLVLIMIAPVLVYLMASLFTYSKD
CCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DPGWSQSGSAIVHNIGGKAGAWIADVLFQLCGFVAFLLPVALGVVSWIALFGSDQEEQAE
CCCCCCCCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GHLEPALRLVGIVGFLIAATGLFHLHLFQSDVARAGGILGKQVCNSLQAGFGVFGTNLFV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHH
LMLLLISVTLATGLSWFALMERIGRVVLAVPPLLQKSKRRADEWQHARALREEREEVRKI
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAVQRAKRDPMKIELPPEPIVEKSERAKRDTQIPMFLGVNKRGSDLPSLALLDNPKPQIK
HHHHHHCCCCCEEECCCCHHHCHHHHHHHCCCCCEEEECCCCCCCCCCEEECCCCCCCCC
GYSDETLEALSRQIELKFKDFRIDVQVVGAYPGPVITRFEIEPARGVKVSQISALDKDIA
CCCHHHHHHHHHHHEEEEEEEEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
RGLSVKSVRVVEVIPGKSVIGLEIPNVNREMIFLSELLRSKEYDKSPSSLTLALGKNIAG
CCCCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
RPTVADLARMPHLLVAGTTGSGKSVAVNAMVLSLLFKASHNDLRMLMIDPKMLELSVYQG
CCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHC
IPHLLAPVVTDMKEAANGLRWCVAEMERRYKLMSAVGVRNLAGFNKKVKDAEEAGQPLMD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCHHH
PLFKPNPDLSEVPRPLQKLPFIVIFIDEFADMMMIVGKKVEELIARLAQKARAAGIHLIL
HCCCCCCCHHHCCCHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
ATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQSGAETLLGHGDMLYLPPGTAMP
ECCCCCHHHHHHHHHCCCCCEEEEEEHHCCCHHHHHCCCCCHHHHCCCCEEEECCCCCCC
ERVHGAFVSDDEVHRVVEYLKASAPVQYVDGVLDEIQTMDDGVVIGPAGFPESASGGGDE
HHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCC
TDPLYDEALRIVTETRRASISSVQRRLRIGYNRAARLIEAMETAGVVSPPEHNGDRAVLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEC
PPPR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]