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The map label for this gene is xerD

Identifier: 182681239

GI number: 182681239

Start: 809292

End: 810266

Strand: Reverse

Name: xerD

Synonym: XfasM23_0684

Alternate gene names: 182681239

Gene position: 810266-809292 (Counterclockwise)

Preceding gene: 182681240

Following gene: 182681238

Centisome position: 31.95

GC content: 56.62

Gene sequence:

>975_bases
ATGACCCTCCGCACCACCAACCAACGCCGCCAACTGGCCAGACAACAACCTCCCCTATTACCCGAAGATGCAACAACCAT
TGCACACTGCCTTGATGCACTCTGGATCAAACACGGACTATCACGGCACACCCTCAACAGCTACCGACGCGACCTGGAAG
GCCTGGCCCGCTGGAACAACGGCCGTGCCGGACCTCTAGCGACCTTAACGCCACCTGCCCTGCTCGATTACCTCACCTGG
CGCACCCAACAACACTATTCCCCACTGAGCAATGCACGCTTACGGTCCGTACTGCGTACCTTCTTTTCCTATGCCGTCGA
ATGCGGCTGGCGCAACGACAACCCAAGCACCCTGCTAGCCCACCCAGTCTTACCCCATCCATTACCGAAAGCACTCACCG
AAAGTCAGATAGAAGCACTCTTAGCCGCACCATCAATAGAAACCCCAGAAGGACTACGTAACCGAGCCATGCTGGAATTG
ATGTATGCCGCCGGCCTGCGCGTCAGTGAATTGGTCACCCTCCCCGTGGCGATGCTGAACCAACGTCAAGGCGTCCTACG
CATCACCGGCAAAGGAGGTAAAGAACGACTCGTCCCACTCGGCGAAGAATCCCAACACTGGCTACAACGCTATTTAGAAC
AGGCACGGCCATCCCTGGCGGCCGACAAACCCATTCCCGCCGACTCGGACGGAGACGTCCCCTTGTTCATCAACACAAAC
CTGAAACGTCTCAGCCGCCAACAATTTTGGAGATGGATCAAACACTATGCCGCCTTGGTCGGCATCGCCCCAAACAAAGT
CAGCCCCCATGTCCTGCGTCACAGCTTTGCAACACATTTACTGAACCACGGCGCAGACCTGCGTGCATTGCAAATGTTGC
TGGGCCATCGCTCCATCTCGACGACACAGATCTACACACTCATCGCACGCCAGCACTTACAACAATTGCACGCCCAACAC
CACCCCCGTGGTTGA

Upstream 100 bases:

>100_bases
AACCTCATGACGAGTGGGTTCTGCAAACAACACCACCGATGTGCAAAACCAACTCAAGTCAATAGACTAAAAGAATGTAC
CGCCCCGCCACACTGCACGG

Downstream 100 bases:

>100_bases
AAAGCACATACGGTAATGACAACGCACCCCAGAACAATGAATACAGACCTGTCCGACCACACCATAGACATCATGATGCA
GCATCCAGCCTGTGAGACAA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTLRTTNQRRQLARQQPPLLPEDATTIAHCLDALWIKHGLSRHTLNSYRRDLEGLARWNNGRAGPLATLTPPALLDYLTW
RTQQHYSPLSNARLRSVLRTFFSYAVECGWRNDNPSTLLAHPVLPHPLPKALTESQIEALLAAPSIETPEGLRNRAMLEL
MYAAGLRVSELVTLPVAMLNQRQGVLRITGKGGKERLVPLGEESQHWLQRYLEQARPSLAADKPIPADSDGDVPLFINTN
LKRLSRQQFWRWIKHYAALVGIAPNKVSPHVLRHSFATHLLNHGADLRALQMLLGHRSISTTQIYTLIARQHLQQLHAQH
HPRG

Sequences:

>Translated_324_residues
MTLRTTNQRRQLARQQPPLLPEDATTIAHCLDALWIKHGLSRHTLNSYRRDLEGLARWNNGRAGPLATLTPPALLDYLTW
RTQQHYSPLSNARLRSVLRTFFSYAVECGWRNDNPSTLLAHPVLPHPLPKALTESQIEALLAAPSIETPEGLRNRAMLEL
MYAAGLRVSELVTLPVAMLNQRQGVLRITGKGGKERLVPLGEESQHWLQRYLEQARPSLAADKPIPADSDGDVPLFINTN
LKRLSRQQFWRWIKHYAALVGIAPNKVSPHVLRHSFATHLLNHGADLRALQMLLGHRSISTTQIYTLIARQHLQQLHAQH
HPRG
>Mature_323_residues
TLRTTNQRRQLARQQPPLLPEDATTIAHCLDALWIKHGLSRHTLNSYRRDLEGLARWNNGRAGPLATLTPPALLDYLTWR
TQQHYSPLSNARLRSVLRTFFSYAVECGWRNDNPSTLLAHPVLPHPLPKALTESQIEALLAAPSIETPEGLRNRAMLELM
YAAGLRVSELVTLPVAMLNQRQGVLRITGKGGKERLVPLGEESQHWLQRYLEQARPSLAADKPIPADSDGDVPLFINTNL
KRLSRQQFWRWIKHYAALVGIAPNKVSPHVLRHSFATHLLNHGADLRALQMLLGHRSISTTQIYTLIARQHLQQLHAQHH
PRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=305, Percent_Identity=52.1311475409836, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1790244, Length=301, Percent_Identity=33.8870431893688, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1790768, Length=178, Percent_Identity=30.3370786516854, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790767, Length=176, Percent_Identity=32.3863636363636, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36673; Mature: 36542

Theoretical pI: Translated: 10.89; Mature: 10.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRTTNQRRQLARQQPPLLPEDATTIAHCLDALWIKHGLSRHTLNSYRRDLEGLARWNN
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
GRAGPLATLTPPALLDYLTWRTQQHYSPLSNARLRSVLRTFFSYAVECGWRNDNPSTLLA
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
HPVLPHPLPKALTESQIEALLAAPSIETPEGLRNRAMLELMYAAGLRVSELVTLPVAMLN
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
QRQGVLRITGKGGKERLVPLGEESQHWLQRYLEQARPSLAADKPIPADSDGDVPLFINTN
CCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCC
LKRLSRQQFWRWIKHYAALVGIAPNKVSPHVLRHSFATHLLNHGADLRALQMLLGHRSIS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCH
TTQIYTLIARQHLQQLHAQHHPRG
HHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLRTTNQRRQLARQQPPLLPEDATTIAHCLDALWIKHGLSRHTLNSYRRDLEGLARWNN
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
GRAGPLATLTPPALLDYLTWRTQQHYSPLSNARLRSVLRTFFSYAVECGWRNDNPSTLLA
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
HPVLPHPLPKALTESQIEALLAAPSIETPEGLRNRAMLELMYAAGLRVSELVTLPVAMLN
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
QRQGVLRITGKGGKERLVPLGEESQHWLQRYLEQARPSLAADKPIPADSDGDVPLFINTN
CCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCC
LKRLSRQQFWRWIKHYAALVGIAPNKVSPHVLRHSFATHLLNHGADLRALQMLLGHRSIS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCH
TTQIYTLIARQHLQQLHAQHHPRG
HHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347; 12050668 [H]