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The map label for this gene is dsbC [H]

Identifier: 182681238

GI number: 182681238

Start: 808372

End: 809160

Strand: Reverse

Name: dsbC [H]

Synonym: XfasM23_0683

Alternate gene names: 182681238

Gene position: 809160-808372 (Counterclockwise)

Preceding gene: 182681239

Following gene: 182681237

Centisome position: 31.91

GC content: 53.74

Gene sequence:

>789_bases
ATGTACCGCCTTATCGCCGCCTTGTTGCTGGGTATCGTGACCCTCACCGCCTGCGCACAACCCTCACAACCCAGCTCCAA
CAAAACGAGCACCACACCAACCAACACCACGCCAGCCAACGTGCAACAACGCGTGACTGCCGCCCTAAACACTCTGGACC
CAGATTTCAAGCCAGACTACATCGGTGCCGCACCATTCCCGGGTTTCCGTGAAGTTGTGGTCAGCGGCCAAATTCTGTAT
GTCAGCGACAACGGCCGCTACCTCATTCAGGCACAACCCTACGACATTCAAAACAAAAAATTTGCTGTCAGCGAAGGGCT
GCTTTCCTACCGCCGCACCCAACTAGCCACAGTGCCCCAATCGCAACGCATCGTGTTCGCACCAAAGAACCCCCAATACA
CCATCAGCGTATTCACCGACATTGAATGCGGCTATTGCCGGAAACTACATAGCGAAATCGCCGAACTGAATAAACAAGGC
ATCGCCGTTGAATACCTCGCCTTCCCACGGATGGGTTTAGGAAGCGAAGATTACAAAGACATGGTCTCAGTGTGGTGCGC
CGCTGATCGTAAACAAGCACTGACCGAAGCAAAAGCCGGCAAAAAAATCCAGAATAAAAATTGTAATAACCCTGTTGCCT
TGGAATACAGCCTAGGTCAACGTATCGGCGTCAACGGCACCCCAGCAATCTTCGCCCCAGACGGCACCCAGCTTGGCGGC
TATCTACCACCAGAAAAACTACGTGCACTGCTGGACAAACTCGCCGCCGCCACAGCTAAAGGGGGCTGA

Upstream 100 bases:

>100_bases
GAACAATGAATACAGACCTGTCCGACCACACCATAGACATCATGATGCAGCATCCAGCCTGTGAGACAATTACAATTCAT
TGTTCCATTTGGATGTTTGA

Downstream 100 bases:

>100_bases
GACCTTCTACCAGAACAGCAAGCCTCCCGCTCCCCTCTGCCACACTCTGCATCACTTCGGCTCCCATGTTGCTACCACCT
CATGCGAGCCGAAGCACTGT

Product: disulfide isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MYRLIAALLLGIVTLTACAQPSQPSSNKTSTTPTNTTPANVQQRVTAALNTLDPDFKPDYIGAAPFPGFREVVVSGQILY
VSDNGRYLIQAQPYDIQNKKFAVSEGLLSYRRTQLATVPQSQRIVFAPKNPQYTISVFTDIECGYCRKLHSEIAELNKQG
IAVEYLAFPRMGLGSEDYKDMVSVWCAADRKQALTEAKAGKKIQNKNCNNPVALEYSLGQRIGVNGTPAIFAPDGTQLGG
YLPPEKLRALLDKLAAATAKGG

Sequences:

>Translated_262_residues
MYRLIAALLLGIVTLTACAQPSQPSSNKTSTTPTNTTPANVQQRVTAALNTLDPDFKPDYIGAAPFPGFREVVVSGQILY
VSDNGRYLIQAQPYDIQNKKFAVSEGLLSYRRTQLATVPQSQRIVFAPKNPQYTISVFTDIECGYCRKLHSEIAELNKQG
IAVEYLAFPRMGLGSEDYKDMVSVWCAADRKQALTEAKAGKKIQNKNCNNPVALEYSLGQRIGVNGTPAIFAPDGTQLGG
YLPPEKLRALLDKLAAATAKGG
>Mature_262_residues
MYRLIAALLLGIVTLTACAQPSQPSSNKTSTTPTNTTPANVQQRVTAALNTLDPDFKPDYIGAAPFPGFREVVVSGQILY
VSDNGRYLIQAQPYDIQNKKFAVSEGLLSYRRTQLATVPQSQRIVFAPKNPQYTISVFTDIECGYCRKLHSEIAELNKQG
IAVEYLAFPRMGLGSEDYKDMVSVWCAADRKQALTEAKAGKKIQNKNCNNPVALEYSLGQRIGVNGTPAIFAPDGTQLGG
YLPPEKLRALLDKLAAATAKGG

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=212, Percent_Identity=36.3207547169811, Blast_Score=161, Evalue=5e-41,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 28462; Mature: 28462

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRLIAALLLGIVTLTACAQPSQPSSNKTSTTPTNTTPANVQQRVTAALNTLDPDFKPDY
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
IGAAPFPGFREVVVSGQILYVSDNGRYLIQAQPYDIQNKKFAVSEGLLSYRRTQLATVPQ
CCCCCCCCHHHHHHCCEEEEEECCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCC
SQRIVFAPKNPQYTISVFTDIECGYCRKLHSEIAELNKQGIAVEYLAFPRMGLGSEDYKD
CCEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHH
MVSVWCAADRKQALTEAKAGKKIQNKNCNNPVALEYSLGQRIGVNGTPAIFAPDGTQLGG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEECCCCCCEEECCCCCCCCC
YLPPEKLRALLDKLAAATAKGG
CCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYRLIAALLLGIVTLTACAQPSQPSSNKTSTTPTNTTPANVQQRVTAALNTLDPDFKPDY
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
IGAAPFPGFREVVVSGQILYVSDNGRYLIQAQPYDIQNKKFAVSEGLLSYRRTQLATVPQ
CCCCCCCCHHHHHHCCEEEEEECCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCC
SQRIVFAPKNPQYTISVFTDIECGYCRKLHSEIAELNKQGIAVEYLAFPRMGLGSEDYKD
CCEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHH
MVSVWCAADRKQALTEAKAGKKIQNKNCNNPVALEYSLGQRIGVNGTPAIFAPDGTQLGG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEECCCCCCEEECCCCCCCCC
YLPPEKLRALLDKLAAATAKGG
CCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8168497 [H]