Click here to switch to the map view.

The map label for this gene is trpB

Identifier: 182681200

GI number: 182681200

Start: 760716

End: 761933

Strand: Direct

Name: trpB

Synonym: XfasM23_0644

Alternate gene names: 182681200

Gene position: 760716-761933 (Clockwise)

Preceding gene: 182681199

Following gene: 182681201

Centisome position: 30.0

GC content: 54.52

Gene sequence:

>1218_bases
ATGTCTGATATTACTGTTGCTAACTATCATGCTTTCCCTGATGCTCGCGGCCATTTTGGGCGTTACGGTGGTCGTTTTGT
TGCTGAAACGTTGATCGGACCGTTGCAGGAGCTTGCACAGGCCTATGATGCGGCGCGCCATGATCCCGATTTCATCGCCG
CTTATAACAAGGATCTCAAGGATTATGTGGGTCGCCCCAGTCCGATCTACCATGCTGAACGGCTGAGCCGTAAGGTGGGT
GGCGCTCAAATTCTGTTGAAGCGTGAGGATCTTAATCACACCGGTGCGCACAAAATCAATAACACCATTGGCCAGGCCTT
GCTGGCAGCACGTATGGGCAAGACACGCATCATTGCCGAGACTGGAGCCGGTCAGCATGGTGTCGCCAGTGCTACTGTCG
CTGCGCGTTTGGGTTTGGAGTGTGTGGTGTATATGGGGGCTACGGATATCCAGCGGCAGCAGATCAACGTGTATCGGATG
AAGTTGTTGGGTGCGACGGTGGTGCCCGTGACTTCCGGTTCAGCCACACTCAAGGATGCGCTTAACGAAGCGATGCGTGA
TTGGGTGACGCATGTGGGGCATACGTTTTATATCATTGGCACTGTTGCTGGCCCAGATCCGTATCCGCGTATGGTGCGCG
ACTTCAACGCAATTGTTGGCCGTGAGGCACGTGCGCAGATGATTGAAGATTATGGGCGTTTACCGGATGCGATGACTGCT
TGTGTTGGCGGTGGGAGTAATGCCATTGGTTTGTTCCATGCCTTCCTCAATGATGCTTCGGTCAGGATCTATGGTGCTGA
GGCGGCTGGAGACGGCATTGCGACGGGCCGTCACGCGGCCTCAATTGTTGCCGGTCGTCCGGGAGTGTTGCATGGGAATC
GCACCTACGTGGTGTGTGATGATGATGGACAGATTTTGGAAACCCATTCTGTATCAGCCGGTTTGGATTATCCGGGGGTT
GGTCCTGAGCACGCTTTTTTGGCTGACAGTGGCCGGGTGCAGTATGTGGGGATTCGGGATGAAGAAGCGTTGGCTGCATT
CCACTTGCTTGCACATACTGAAGGCATCTTGGCTGCATTGGAATCCAGTCACGCTGTGGCCCATACCATGACGTTGGCGC
GCGATCTTCCCAAAGATGCATTGGTACTGTGTAACTTGTCCGGTCGCGGTGATAAGGATGTGCACACGATCGCGGCGCGC
GAAGGTGTACGTGTCTGA

Upstream 100 bases:

>100_bases
GGTACTGTGTGCTTCTTTGAATTCGATCAGCGTGGAGAATATTGATTCTTTGAGTGCTGGGGTGCGTTACAGTGACGGCG
TGTTTTTGCTGGTGCCCGTC

Downstream 100 bases:

>100_bases
GTGTATGGGGATGTGTCACTGCGGTAGGGTGCGGTGATAGCACTGTGGCCATTGTCTGGCGGAGACCAGGTGATGTTGCC
GTGATGCCAATGATTTTCTG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSDITVANYHAFPDARGHFGRYGGRFVAETLIGPLQELAQAYDAARHDPDFIAAYNKDLKDYVGRPSPIYHAERLSRKVG
GAQILLKREDLNHTGAHKINNTIGQALLAARMGKTRIIAETGAGQHGVASATVAARLGLECVVYMGATDIQRQQINVYRM
KLLGATVVPVTSGSATLKDALNEAMRDWVTHVGHTFYIIGTVAGPDPYPRMVRDFNAIVGREARAQMIEDYGRLPDAMTA
CVGGGSNAIGLFHAFLNDASVRIYGAEAAGDGIATGRHAASIVAGRPGVLHGNRTYVVCDDDGQILETHSVSAGLDYPGV
GPEHAFLADSGRVQYVGIRDEEALAAFHLLAHTEGILAALESSHAVAHTMTLARDLPKDALVLCNLSGRGDKDVHTIAAR
EGVRV

Sequences:

>Translated_405_residues
MSDITVANYHAFPDARGHFGRYGGRFVAETLIGPLQELAQAYDAARHDPDFIAAYNKDLKDYVGRPSPIYHAERLSRKVG
GAQILLKREDLNHTGAHKINNTIGQALLAARMGKTRIIAETGAGQHGVASATVAARLGLECVVYMGATDIQRQQINVYRM
KLLGATVVPVTSGSATLKDALNEAMRDWVTHVGHTFYIIGTVAGPDPYPRMVRDFNAIVGREARAQMIEDYGRLPDAMTA
CVGGGSNAIGLFHAFLNDASVRIYGAEAAGDGIATGRHAASIVAGRPGVLHGNRTYVVCDDDGQILETHSVSAGLDYPGV
GPEHAFLADSGRVQYVGIRDEEALAAFHLLAHTEGILAALESSHAVAHTMTLARDLPKDALVLCNLSGRGDKDVHTIAAR
EGVRV
>Mature_404_residues
SDITVANYHAFPDARGHFGRYGGRFVAETLIGPLQELAQAYDAARHDPDFIAAYNKDLKDYVGRPSPIYHAERLSRKVGG
AQILLKREDLNHTGAHKINNTIGQALLAARMGKTRIIAETGAGQHGVASATVAARLGLECVVYMGATDIQRQQINVYRMK
LLGATVVPVTSGSATLKDALNEAMRDWVTHVGHTFYIIGTVAGPDPYPRMVRDFNAIVGREARAQMIEDYGRLPDAMTAC
VGGGSNAIGLFHAFLNDASVRIYGAEAAGDGIATGRHAASIVAGRPGVLHGNRTYVVCDDDGQILETHSVSAGLDYPGVG
PEHAFLADSGRVQYVGIRDEEALAAFHLLAHTEGILAALESSHAVAHTMTLARDLPKDALVLCNLSGRGDKDVHTIAARE
GVRV

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=381, Percent_Identity=53.2808398950131, Blast_Score=419, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321412, Length=381, Percent_Identity=53.8057742782152, Blast_Score=437, Evalue=1e-123,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_XYLF2 (B2I9J2)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829360.1
- ProteinModelPortal:   B2I9J2
- SMR:   B2I9J2
- GeneID:   6203311
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0644
- HOGENOM:   HBG303148
- OMA:   LKREDLC
- ProtClustDB:   PRK04346
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 43248; Mature: 43116

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDITVANYHAFPDARGHFGRYGGRFVAETLIGPLQELAQAYDAARHDPDFIAAYNKDLK
CCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHH
DYVGRPSPIYHAERLSRKVGGAQILLKREDLNHTGAHKINNTIGQALLAARMGKTRIIAE
HHCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
TGAGQHGVASATVAARLGLECVVYMGATDIQRQQINVYRMKLLGATVVPVTSGSATLKDA
CCCCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHH
LNEAMRDWVTHVGHTFYIIGTVAGPDPYPRMVRDFNAIVGREARAQMIEDYGRLPDAMTA
HHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHH
CVGGGSNAIGLFHAFLNDASVRIYGAEAAGDGIATGRHAASIVAGRPGVLHGNRTYVVCD
HHCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCEEECCEEEEEEC
DDGQILETHSVSAGLDYPGVGPEHAFLADSGRVQYVGIRDEEALAAFHLLAHTEGILAAL
CCCCEEEECCCCCCCCCCCCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
ESSHAVAHTMTLARDLPKDALVLCNLSGRGDKDVHTIAAREGVRV
HCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SDITVANYHAFPDARGHFGRYGGRFVAETLIGPLQELAQAYDAARHDPDFIAAYNKDLK
CCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHH
DYVGRPSPIYHAERLSRKVGGAQILLKREDLNHTGAHKINNTIGQALLAARMGKTRIIAE
HHCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
TGAGQHGVASATVAARLGLECVVYMGATDIQRQQINVYRMKLLGATVVPVTSGSATLKDA
CCCCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHH
LNEAMRDWVTHVGHTFYIIGTVAGPDPYPRMVRDFNAIVGREARAQMIEDYGRLPDAMTA
HHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHH
CVGGGSNAIGLFHAFLNDASVRIYGAEAAGDGIATGRHAASIVAGRPGVLHGNRTYVVCD
HHCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCEEECCEEEEEEC
DDGQILETHSVSAGLDYPGVGPEHAFLADSGRVQYVGIRDEEALAAFHLLAHTEGILAAL
CCCCEEEECCCCCCCCCCCCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
ESSHAVAHTMTLARDLPKDALVLCNLSGRGDKDVHTIAAREGVRV
HCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA