Click here to switch to the map view.

The map label for this gene is aroK

Identifier: 182681169

GI number: 182681169

Start: 723493

End: 724035

Strand: Reverse

Name: aroK

Synonym: XfasM23_0611

Alternate gene names: 182681169

Gene position: 724035-723493 (Counterclockwise)

Preceding gene: 182681171

Following gene: 182681168

Centisome position: 28.55

GC content: 53.04

Gene sequence:

>543_bases
ATGAATCCCGCCCCTAATCTTGTGATGATCGGCCCGATGGGCGCCGGAAAAAGCTCCATCGGACGACGCATTGCCAAACA
CTTCAACCTACACTTCGCAGATACAGATCACGCCATTGTTGAACGCGCCGGTACGAGCATCTCCACTATTTTCAAATATT
CCGGCGAACCAGAATTTCGACGCCTGGAGCGTGAAGTACTGTACGACTTGCTGAATCACGAAAACCGACTCATCGCCACC
GGCGGCGGTACGATCCTGGATCCAGAGAACCGCCACCGCATGCAAAAACGCGGCTTCGTCGTATTTCTAAAGATCAACGT
GAACACCCAATTGGAGCGACTGGCACATGACCGCTACCGACCATTACTGCAACAAATCGACCGCAAACAGGTACTGAGCG
ATCTCTACGCCACACGCCAACCGCTCTACCAGAAAATCGCAGATATGATTGTGACCACCGACCACATGTCCCCTAACACA
GCCACCGCCCAGCTCATTCTGGACTTAACAGCCCACTGGCAGAAATCAAGCAACACCGCATGA

Upstream 100 bases:

>100_bases
CCAAATCACCATCCAATACACCTCAAACAATCACACCTCCAATATCACCGTGCACGTGATCGAACGCGCAACAAATCGGC
AGTGATAACATCAACACGTT

Downstream 100 bases:

>100_bases
CCACTCCCACACCACTGCGCAGCGTCACCGTCAACACCCCCCCCCCCTATACCATCGCCATTGGTCCCGGCCTATTGCAC
GATCCTCCACGCCTGGCCGC

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MNPAPNLVMIGPMGAGKSSIGRRIAKHFNLHFADTDHAIVERAGTSISTIFKYSGEPEFRRLEREVLYDLLNHENRLIAT
GGGTILDPENRHRMQKRGFVVFLKINVNTQLERLAHDRYRPLLQQIDRKQVLSDLYATRQPLYQKIADMIVTTDHMSPNT
ATAQLILDLTAHWQKSSNTA

Sequences:

>Translated_180_residues
MNPAPNLVMIGPMGAGKSSIGRRIAKHFNLHFADTDHAIVERAGTSISTIFKYSGEPEFRRLEREVLYDLLNHENRLIAT
GGGTILDPENRHRMQKRGFVVFLKINVNTQLERLAHDRYRPLLQQIDRKQVLSDLYATRQPLYQKIADMIVTTDHMSPNT
ATAQLILDLTAHWQKSSNTA
>Mature_180_residues
MNPAPNLVMIGPMGAGKSSIGRRIAKHFNLHFADTDHAIVERAGTSISTIFKYSGEPEFRRLEREVLYDLLNHENRLIAT
GGGTILDPENRHRMQKRGFVVFLKINVNTQLERLAHDRYRPLLQQIDRKQVLSDLYATRQPLYQKIADMIVTTDHMSPNT
ATAQLILDLTAHWQKSSNTA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=167, Percent_Identity=38.9221556886228, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786587, Length=148, Percent_Identity=31.7567567567568, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_XYLF2 (B2I9G1)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829329.1
- ProteinModelPortal:   B2I9G1
- SMR:   B2I9G1
- GeneID:   6203698
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0611
- HOGENOM:   HBG335815
- OMA:   VIYLRAN
- ProtClustDB:   PRK00131
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 20489; Mature: 20489

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 36-36 BINDING 60-60 BINDING 82-82 BINDING 120-120 BINDING 139-139

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPAPNLVMIGPMGAGKSSIGRRIAKHFNLHFADTDHAIVERAGTSISTIFKYSGEPEFR
CCCCCCEEEEECCCCCHHHHHHHHHHHHCCEECCCCHHHHHHCCCCHHHHEECCCCHHHH
RLEREVLYDLLNHENRLIATGGGTILDPENRHRMQKRGFVVFLKINVNTQLERLAHDRYR
HHHHHHHHHHHCCCCEEEEECCCEEECCCHHHHHHHCCEEEEEEEECCHHHHHHHHHHHH
PLLQQIDRKQVLSDLYATRQPLYQKIADMIVTTDHMSPNTATAQLILDLTAHWQKSSNTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNPAPNLVMIGPMGAGKSSIGRRIAKHFNLHFADTDHAIVERAGTSISTIFKYSGEPEFR
CCCCCCEEEEECCCCCHHHHHHHHHHHHCCEECCCCHHHHHHCCCCHHHHEECCCCHHHH
RLEREVLYDLLNHENRLIATGGGTILDPENRHRMQKRGFVVFLKINVNTQLERLAHDRYR
HHHHHHHHHHHCCCCEEEEECCCEEECCCHHHHHHHCCEEEEEEEECCHHHHHHHHHHHH
PLLQQIDRKQVLSDLYATRQPLYQKIADMIVTTDHMSPNTATAQLILDLTAHWQKSSNTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA