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The map label for this gene is mreD [H]

Identifier: 182681147

GI number: 182681147

Start: 696409

End: 696894

Strand: Direct

Name: mreD [H]

Synonym: XfasM23_0589

Alternate gene names: 182681147

Gene position: 696409-696894 (Clockwise)

Preceding gene: 182681146

Following gene: 182681148

Centisome position: 27.46

GC content: 53.7

Gene sequence:

>486_bases
ATGACCCGGCTGCGTAATACTTGGTTATTGCCGGTCAGCGTGATATTGGCCTTGCTTCTGGGGTTACTTCCGTTACCAGT
GTCAGTGCGGCCAATCCGTCCTTACTGGTTAGCGTTGGTGCTGATGTACTGGGTGATCGAGACGCCTGGTCGCGTTGGAA
TCGGTTTCGCTTTTGTAATGGGTGTACTGGCTGACTTCATTTATGGTGGTTTGTTAGGGGAGCAGGCGTTGCGTCTGGTG
GTGATGTCCTTCATCGTGCAACGTTTTCGAGCCCGCCTGCGCTTCTTCCCGATGCCGCAGCAGGCGTTGGTCATCGGTGG
CTTGCTATTCAACGATTGTGTAGTTGCTACGGCGTTGCATTTGACCTTGGGTCAGCCATTGTTGCCCTGGAGTTATTGGT
CGGCACCGCTATTGGGAATGTTGTTGTGGGCACCGTTGTTTGTGTTGCTGGATGCGTTGCGACTAGGTCATGGGAGTCGG
AAGTGA

Upstream 100 bases:

>100_bases
GTGGTGGAGGGTCGTTAACATCAAGATCTATTATTGACTCAAACAGTGAGTCTCACTCCACCAATCTTGGCGCTTCCAGG
GTAATCAAGGAGCCGCAGCA

Downstream 100 bases:

>100_bases
TCCGATGAGCGTGCATCATCCACAAGCAAAGCATACGTATGCCGAAGTTGAGCAGTTTCGCCGCCGTGCTTTGCTGAGCT
TGTTTGTTGTAGTGGTGTGT

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTRLRNTWLLPVSVILALLLGLLPLPVSVRPIRPYWLALVLMYWVIETPGRVGIGFAFVMGVLADFIYGGLLGEQALRLV
VMSFIVQRFRARLRFFPMPQQALVIGGLLFNDCVVATALHLTLGQPLLPWSYWSAPLLGMLLWAPLFVLLDALRLGHGSR
K

Sequences:

>Translated_161_residues
MTRLRNTWLLPVSVILALLLGLLPLPVSVRPIRPYWLALVLMYWVIETPGRVGIGFAFVMGVLADFIYGGLLGEQALRLV
VMSFIVQRFRARLRFFPMPQQALVIGGLLFNDCVVATALHLTLGQPLLPWSYWSAPLLGMLLWAPLFVLLDALRLGHGSR
K
>Mature_160_residues
TRLRNTWLLPVSVILALLLGLLPLPVSVRPIRPYWLALVLMYWVIETPGRVGIGFAFVMGVLADFIYGGLLGEQALRLVV
MSFIVQRFRARLRFFPMPQQALVIGGLLFNDCVVATALHLTLGQPLLPWSYWSAPLLGMLLWAPLFVLLDALRLGHGSRK

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=153, Percent_Identity=32.6797385620915, Blast_Score=74, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 18049; Mature: 17918

Theoretical pI: Translated: 11.57; Mature: 11.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLRNTWLLPVSVILALLLGLLPLPVSVRPIRPYWLALVLMYWVIETPGRVGIGFAFVM
CCCCCCCEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
GVLADFIYGGLLGEQALRLVVMSFIVQRFRARLRFFPMPQQALVIGGLLFNDCVVATALH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LTLGQPLLPWSYWSAPLLGMLLWAPLFVLLDALRLGHGSRK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TRLRNTWLLPVSVILALLLGLLPLPVSVRPIRPYWLALVLMYWVIETPGRVGIGFAFVM
CCCCCCEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
GVLADFIYGGLLGEQALRLVVMSFIVQRFRARLRFFPMPQQALVIGGLLFNDCVVATALH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LTLGQPLLPWSYWSAPLLGMLLWAPLFVLLDALRLGHGSRK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]