Click here to switch to the map view.

The map label for this gene is etfD [H]

Identifier: 182681132

GI number: 182681132

Start: 683051

End: 684697

Strand: Reverse

Name: etfD [H]

Synonym: XfasM23_0574

Alternate gene names: 182681132

Gene position: 684697-683051 (Counterclockwise)

Preceding gene: 182681134

Following gene: 182681131

Centisome position: 27.0

GC content: 53.49

Gene sequence:

>1647_bases
ATGTTGGCAGCGAAACAGGAGACAGAAACAAACACCATTGAGCGTGACGTCATGGAATACGACGTTGTCACCGTCGGCTC
TGGCCCAGCAGGCTTAGCTTTTGCAATCCGCCTGAAACAACTCAACCCTGCCTTGTCGGTATGCGTGATCGAAAAATCCA
GCACAATCGGCGGACATATTCTCTCTGGCGCAGTGATCGAACCTGCCCCCCTGGATAGCCTACTCCCTGGCTGGCGCAAC
GCCCCACCTCCAATCTGCGTCCCTGCAACCGAGGACGAATTCTGGCTCCTGAGCAAAAATGGCGCATACAAATTTCCGAT
CATGCCGCCGAGCTTGCGCAACCACGGTAACGTGATCGTCAGCCTTGGCGCACTATGCGCCTGGTTAGCACCTCAAGCCG
AGACACTGGGCGTAGACATTTACCCAGGCTTCTCCGCCACTGAAACCCTGCACGACGCGGCTGGCCAAGTCATTGGAGTG
CGCATTGGCGACATGGGTATCGCTAAAAACGGAACACACAAACCTAGCTTCACCCCAGGCATTGCAATCAAGGCAAAGGT
CACAGTACTTGCCGAAGGCGCACGCGGCCACCTGACCAAACACCTGATTAAACATTTCTCACTAGATCAAAACAGTGATC
CGCAAACCTACTCCATCGGAATCAAAGAACTATGGCACGTCCCAGAAAAACGTAGCTCTCCAGGCAAAATCTTACATACC
CTCGGCTGGCCAGCCGATACACATACCTACGGAGGTGGCTTTCTCTATCACCTGAATGACAATCGCATCGCACTAGGTTA
TGTCAGCGGCCTGGACTATCACGACCCAAGGTACGAACCCTGGGAAGCATTCCAGCAATGGAAAAACCACCCACTCATCA
AACCGCTTCTGGAAAGTGGTGACCTCCTATCGGGCGGCGCACGTGCAATCGTCACTGGCGGCTGGCAATCCCTCCCCAAA
GTGGACATGCCAGGCGCACTGTTGATCGGTGACACTGCCGGCTTACTCAACGTCCCTAAGATCAAGGGAACACACCAAGC
AATCCGCAGCGGCATGCTCGCCGCCGAACATCTCGTCGCCACCCAACTCATCCCCTATGGATTTGATGCCAAACTGCGTG
CTTCAAAGGCAATGACCGAATTAAAACAAGTACGCAATATCAAGCCAGGTTTCAAAAAAGGCTTATGGTTGGGCCTACTG
AACGCCGCCTGGGAGACAGCTACCCGTGGCGCTTCTCCATGGACATTGAAAAACACACCAGACTGGGCCGCACTGCAACG
GCTCGACAAAAACCAACAAACAAAACACGACTACGTACAACGCACCTTACCGCCACGCGACCGCCTGCATAGCGTCTACT
TCGCGGCCACTGTGCACAATGAAGATCAACCCATCCATCTAAAAGTCACCGACCCCGAACGATGCGTCACACGCTGCGTA
GAGGAATACGGCAATCCATGCACCCGCTTCTGTCCGGCCAACGTCTACCAAATCATTGAGGACCCCAACTCAGCAACCAA
CAAACGCTTACACATCAATGCAGCCAACTGCGTGCACTGTAAAACCTGTGACATCAAAGATCCGTACCAGATTATCGACT
GGATCACCCCAGAAGGCGGATCAGGCCCAAATTATCAAAACCTATAA

Upstream 100 bases:

>100_bases
CCCCCTAACACGACAAACCAGGACACAGCAGTCATTTGCTGCTATTACAGAACTCCAGGAAAATAATCAAAAGCTATCAC
GCTTATTTCAGGAGCAAAGC

Downstream 100 bases:

>100_bases
GCACCCATCGACACCGTAGGAATATCAAAAGCACAAAAAAATAAACAAATATCATTCCGAAAGATTAGTAACCACATCAT
CAAAAATGGATAAAACACTA

Product: electron-transferring-flavoprotein dehydrogenase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MLAAKQETETNTIERDVMEYDVVTVGSGPAGLAFAIRLKQLNPALSVCVIEKSSTIGGHILSGAVIEPAPLDSLLPGWRN
APPPICVPATEDEFWLLSKNGAYKFPIMPPSLRNHGNVIVSLGALCAWLAPQAETLGVDIYPGFSATETLHDAAGQVIGV
RIGDMGIAKNGTHKPSFTPGIAIKAKVTVLAEGARGHLTKHLIKHFSLDQNSDPQTYSIGIKELWHVPEKRSSPGKILHT
LGWPADTHTYGGGFLYHLNDNRIALGYVSGLDYHDPRYEPWEAFQQWKNHPLIKPLLESGDLLSGGARAIVTGGWQSLPK
VDMPGALLIGDTAGLLNVPKIKGTHQAIRSGMLAAEHLVATQLIPYGFDAKLRASKAMTELKQVRNIKPGFKKGLWLGLL
NAAWETATRGASPWTLKNTPDWAALQRLDKNQQTKHDYVQRTLPPRDRLHSVYFAATVHNEDQPIHLKVTDPERCVTRCV
EEYGNPCTRFCPANVYQIIEDPNSATNKRLHINAANCVHCKTCDIKDPYQIIDWITPEGGSGPNYQNL

Sequences:

>Translated_548_residues
MLAAKQETETNTIERDVMEYDVVTVGSGPAGLAFAIRLKQLNPALSVCVIEKSSTIGGHILSGAVIEPAPLDSLLPGWRN
APPPICVPATEDEFWLLSKNGAYKFPIMPPSLRNHGNVIVSLGALCAWLAPQAETLGVDIYPGFSATETLHDAAGQVIGV
RIGDMGIAKNGTHKPSFTPGIAIKAKVTVLAEGARGHLTKHLIKHFSLDQNSDPQTYSIGIKELWHVPEKRSSPGKILHT
LGWPADTHTYGGGFLYHLNDNRIALGYVSGLDYHDPRYEPWEAFQQWKNHPLIKPLLESGDLLSGGARAIVTGGWQSLPK
VDMPGALLIGDTAGLLNVPKIKGTHQAIRSGMLAAEHLVATQLIPYGFDAKLRASKAMTELKQVRNIKPGFKKGLWLGLL
NAAWETATRGASPWTLKNTPDWAALQRLDKNQQTKHDYVQRTLPPRDRLHSVYFAATVHNEDQPIHLKVTDPERCVTRCV
EEYGNPCTRFCPANVYQIIEDPNSATNKRLHINAANCVHCKTCDIKDPYQIIDWITPEGGSGPNYQNL
>Mature_548_residues
MLAAKQETETNTIERDVMEYDVVTVGSGPAGLAFAIRLKQLNPALSVCVIEKSSTIGGHILSGAVIEPAPLDSLLPGWRN
APPPICVPATEDEFWLLSKNGAYKFPIMPPSLRNHGNVIVSLGALCAWLAPQAETLGVDIYPGFSATETLHDAAGQVIGV
RIGDMGIAKNGTHKPSFTPGIAIKAKVTVLAEGARGHLTKHLIKHFSLDQNSDPQTYSIGIKELWHVPEKRSSPGKILHT
LGWPADTHTYGGGFLYHLNDNRIALGYVSGLDYHDPRYEPWEAFQQWKNHPLIKPLLESGDLLSGGARAIVTGGWQSLPK
VDMPGALLIGDTAGLLNVPKIKGTHQAIRSGMLAAEHLVATQLIPYGFDAKLRASKAMTELKQVRNIKPGFKKGLWLGLL
NAAWETATRGASPWTLKNTPDWAALQRLDKNQQTKHDYVQRTLPPRDRLHSVYFAATVHNEDQPIHLKVTDPERCVTRCV
EEYGNPCTRFCPANVYQIIEDPNSATNKRLHINAANCVHCKTCDIKDPYQIIDWITPEGGSGPNYQNL

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=563, Percent_Identity=45.1154529307282, Blast_Score=463, Evalue=1e-130,
Organism=Escherichia coli, GI1787991, Length=328, Percent_Identity=28.0487804878049, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786227, Length=330, Percent_Identity=26.6666666666667, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI87082155, Length=335, Percent_Identity=27.1641791044776, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25144720, Length=556, Percent_Identity=42.2661870503597, Blast_Score=442, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6324932, Length=567, Percent_Identity=37.9188712522046, Blast_Score=373, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24652256, Length=556, Percent_Identity=43.705035971223, Blast_Score=455, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 60041; Mature: 60041

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAAKQETETNTIERDVMEYDVVTVGSGPAGLAFAIRLKQLNPALSVCVIEKSSTIGGHI
CCCCCCCCCHHHHHHHHHHEEEEEECCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCEE
LSGAVIEPAPLDSLLPGWRNAPPPICVPATEDEFWLLSKNGAYKFPIMPPSLRNHGNVIV
CCCCEECCCCCHHHCCCCCCCCCCEEEECCCCCEEEEECCCCEECCCCCCCCCCCCCEEE
SLGALCAWLAPQAETLGVDIYPGFSATETLHDAAGQVIGVRIGDMGIAKNGTHKPSFTPG
EHHHHHHHHCCCCHHEEEEEECCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCC
IAIKAKVTVLAEGARGHLTKHLIKHFSLDQNSDPQTYSIGIKELWHVPEKRSSPGKILHT
EEEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHCCCCCCCCCCCEEEE
LGWPADTHTYGGGFLYHLNDNRIALGYVSGLDYHDPRYEPWEAFQQWKNHPLIKPLLESG
CCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHHHCC
DLLSGGARAIVTGGWQSLPKVDMPGALLIGDTAGLLNVPKIKGTHQAIRSGMLAAEHLVA
CCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHCHHHHHHHHH
TQLIPYGFDAKLRASKAMTELKQVRNIKPGFKKGLWLGLLNAAWETATRGASPWTLKNTP
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DWAALQRLDKNQQTKHDYVQRTLPPRDRLHSVYFAATVHNEDQPIHLKVTDPERCVTRCV
CHHHHHHHCCCCHHHHHHHHHCCCCHHHHCEEEEEEEECCCCCEEEEEECCHHHHHHHHH
EEYGNPCTRFCPANVYQIIEDPNSATNKRLHINAANCVHCKTCDIKDPYQIIDWITPEGG
HHHCCCHHHCCCCHHHHHHCCCCCCCCCEEEEECCCEEEEEECCCCCCHHHHEEECCCCC
SGPNYQNL
CCCCCCCC
>Mature Secondary Structure
MLAAKQETETNTIERDVMEYDVVTVGSGPAGLAFAIRLKQLNPALSVCVIEKSSTIGGHI
CCCCCCCCCHHHHHHHHHHEEEEEECCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCEE
LSGAVIEPAPLDSLLPGWRNAPPPICVPATEDEFWLLSKNGAYKFPIMPPSLRNHGNVIV
CCCCEECCCCCHHHCCCCCCCCCCEEEECCCCCEEEEECCCCEECCCCCCCCCCCCCEEE
SLGALCAWLAPQAETLGVDIYPGFSATETLHDAAGQVIGVRIGDMGIAKNGTHKPSFTPG
EHHHHHHHHCCCCHHEEEEEECCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCC
IAIKAKVTVLAEGARGHLTKHLIKHFSLDQNSDPQTYSIGIKELWHVPEKRSSPGKILHT
EEEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHCCCCCCCCCCCEEEE
LGWPADTHTYGGGFLYHLNDNRIALGYVSGLDYHDPRYEPWEAFQQWKNHPLIKPLLESG
CCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHHHCC
DLLSGGARAIVTGGWQSLPKVDMPGALLIGDTAGLLNVPKIKGTHQAIRSGMLAAEHLVA
CCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHCHHHHHHHHH
TQLIPYGFDAKLRASKAMTELKQVRNIKPGFKKGLWLGLLNAAWETATRGASPWTLKNTP
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DWAALQRLDKNQQTKHDYVQRTLPPRDRLHSVYFAATVHNEDQPIHLKVTDPERCVTRCV
CHHHHHHHCCCCHHHHHHHHHCCCCHHHHCEEEEEEEECCCCCEEEEEECCHHHHHHHHH
EEYGNPCTRFCPANVYQIIEDPNSATNKRLHINAANCVHCKTCDIKDPYQIIDWITPEGG
HHHCCCHHHCCCCHHHHHHCCCCCCCCCEEEEECCCEEEEEECCCCCCHHHHEEECCCCC
SGPNYQNL
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]