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The map label for this gene is cbhA [H]

Identifier: 182681111

GI number: 182681111

Start: 657818

End: 659737

Strand: Reverse

Name: cbhA [H]

Synonym: XfasM23_0553

Alternate gene names: 182681111

Gene position: 659737-657818 (Counterclockwise)

Preceding gene: 182681112

Following gene: 182681110

Centisome position: 26.02

GC content: 43.7

Gene sequence:

>1920_bases
ATGTCTGTTTCACTATTAGCGGGAGGTTTATTTTCAACCTCATATGTTTACGCTGAAGCTCATGTCGATAACCCCTTTGT
TGACGCGACCTCCTATCTGAATCCAGATTATTCAAAAGATATTGATACTTCCATTACGAAAGTAAGTGATGTGTCATTAA
AAGAAAAAATGGAAACCATTAAGCACTACCCTACAGGGGTTTGGCTTGATACGATTGATGCGGTAAAAGGTGGCGCCAAA
AATCCAGGACGTCTTAATCTCACAGGCCATCTAGATGCTGCATTAGCACAGAAAAAAGGAAATACGCCTATTACAGCAAC
CTTTGTTATTTATGACATACCTGGACGCGATTGCCACGCATTAGCTTCCAATGGAGAATTGCCTTTAAATTCAGCATCTC
TGGAACGTTATAAAAGAGAATATATTGATACGATTGCCAGTATTTTTTCAAATCCAAAATATAAAGATATCCGCATTGTC
AATATTATTGAACCGGATAGCTTACCAAATCTTATCACCAACTTGAGCACCCCTAGTTGTGCCAAAGCAAAAAATACCGG
AATTTACGAAGAAGGCATTAAATATGCACTTAATAAATTTTCTGAAATTCCAAATGTATACAACTACATGGACATCGGTC
ACGCTGGCTGGCTAGGATGGGATACTAACCGGATACCAGCAGTCTCTTTGTACACCAAGGTCATTCAAAGTACTACAGCA
GGTTTTGCTAGTGTCAATGGTTTTGCCACCAACACTGCAAACACTACACCGTTGATTGAACCAAACCTACCAAATGCTGA
TCTAAATATCGGTGGACAGCCTATTAGATCCTCTAAATTCTACGACTGGAATCGTTATTTTGACGAAATGGATTATTCAG
AAACTTTGTATAACGATTTTATCGCTGCTGGCTGGCCATCCAGTATCGGATTCATCATTGATACTGGACGTAACGGATGG
GGTGGATCTCAACGCCCAACGTCCGCTTTCGGAAACGATATTAATAGTTATGTGAATTCTGGACGTATAGACCGTCGTAA
TCACCGTGGTAATTGGTGTAATCAGCAGGATGCAGGGATAGGTTTACCTCCAACTGTAACTCCAGGTGGCCATGTGGATG
CTTTTCAATGGATTAAACCACCAGGTTACTCCGATGGTTCCAGCTCACTGATTCCAAACGATCAAGGTAAAGGCTTTGAC
CGGTACTGTGATCCTACATTTACAACACCAGATGGCGTGCTAACAGGTGCATTACCTGACGCTCCACTCTCTGGTGATTG
GTTCCATGCTCAATTTGTAAAATTAATCAACAACGCTTATCCCGATATCAGTCGCACTCCACTCCCCAGCTCCGGTTCTA
GTTCTAGTTCTAGTTCTAGTTCTAGTTCTAGTTCTAGTTCTAGTTCTAGTTCTAGTTCTAGTTCTAGTTCTAGTTCTAGT
TCTAGTTCTAGTTCTAGTTCCAGCTCCGGTTCTAGTTCCAGCTCCGGTTCTAGTTCCAGCTCCGGTTCTAGTTCCAGCTC
CGGTTCTACTTCCAGCTCCGGTTCTACTTCCAGCTCCGGTTCTACTTCCAGCTCCGGTTCTACTTCCAGCTCCGGTTCTA
GCTCCGGTACTGGTTTTAACCCTGGTGCTGGTTTTAACCCTGGTGCTGGCTCCGATCCAACTAAAAACCCTATTACTTCT
AGTATCACCGTGGACAGCGATTGGTATACTGGCTACTGCGAGCGTGTCAAGGTGACTAATACCGGCAGCAGTCGCAGCAA
CTGGACAGTAACGATTCCACTCAAGGGGACGATCCAGACCCTATGGAGTGCGACTTGGTCACTGAGTGGTAGTGACAAGC
TCATCGCTTCTGGTCTGAACTGGAATAAGACGCTTGAACCGAACGGCACAACAGAATTCGGTTTCTGTGCAAACTATTGA

Upstream 100 bases:

>100_bases
TATACCCCCCAATAAACCATCCAAAAAATCCTCCATTTAAAACTACAAGGTGAATAGTTTGAAATTCCCTGAAAGTATCT
TGAAAACCTTAAAATATACG

Downstream 100 bases:

>100_bases
GGTACGTTTTTCACTCCGGCGGCACATCGCCGCCGGAGTAGTTGCGAGCTTAGACTTTCATCCCCCCAATAAAAACTAAG
CACCATACCTATACGTTCCC

Product: cellulose 1,4-beta-cellobiosidase

Products: NA

Alternate protein names: 1,4-beta-cellobiohydrolase A; CBP95; Exocellobiohydrolase A [H]

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MSVSLLAGGLFSTSYVYAEAHVDNPFVDATSYLNPDYSKDIDTSITKVSDVSLKEKMETIKHYPTGVWLDTIDAVKGGAK
NPGRLNLTGHLDAALAQKKGNTPITATFVIYDIPGRDCHALASNGELPLNSASLERYKREYIDTIASIFSNPKYKDIRIV
NIIEPDSLPNLITNLSTPSCAKAKNTGIYEEGIKYALNKFSEIPNVYNYMDIGHAGWLGWDTNRIPAVSLYTKVIQSTTA
GFASVNGFATNTANTTPLIEPNLPNADLNIGGQPIRSSKFYDWNRYFDEMDYSETLYNDFIAAGWPSSIGFIIDTGRNGW
GGSQRPTSAFGNDINSYVNSGRIDRRNHRGNWCNQQDAGIGLPPTVTPGGHVDAFQWIKPPGYSDGSSSLIPNDQGKGFD
RYCDPTFTTPDGVLTGALPDAPLSGDWFHAQFVKLINNAYPDISRTPLPSSGSSSSSSSSSSSSSSSSSSSSSSSSSSSS
SSSSSSSSSGSSSSSGSSSSSGSSSSSGSTSSSGSTSSSGSTSSSGSTSSSGSSSGTGFNPGAGFNPGAGSDPTKNPITS
SITVDSDWYTGYCERVKVTNTGSSRSNWTVTIPLKGTIQTLWSATWSLSGSDKLIASGLNWNKTLEPNGTTEFGFCANY

Sequences:

>Translated_639_residues
MSVSLLAGGLFSTSYVYAEAHVDNPFVDATSYLNPDYSKDIDTSITKVSDVSLKEKMETIKHYPTGVWLDTIDAVKGGAK
NPGRLNLTGHLDAALAQKKGNTPITATFVIYDIPGRDCHALASNGELPLNSASLERYKREYIDTIASIFSNPKYKDIRIV
NIIEPDSLPNLITNLSTPSCAKAKNTGIYEEGIKYALNKFSEIPNVYNYMDIGHAGWLGWDTNRIPAVSLYTKVIQSTTA
GFASVNGFATNTANTTPLIEPNLPNADLNIGGQPIRSSKFYDWNRYFDEMDYSETLYNDFIAAGWPSSIGFIIDTGRNGW
GGSQRPTSAFGNDINSYVNSGRIDRRNHRGNWCNQQDAGIGLPPTVTPGGHVDAFQWIKPPGYSDGSSSLIPNDQGKGFD
RYCDPTFTTPDGVLTGALPDAPLSGDWFHAQFVKLINNAYPDISRTPLPSSGSSSSSSSSSSSSSSSSSSSSSSSSSSSS
SSSSSSSSSGSSSSSGSSSSSGSSSSSGSTSSSGSTSSSGSTSSSGSTSSSGSSSGTGFNPGAGFNPGAGSDPTKNPITS
SITVDSDWYTGYCERVKVTNTGSSRSNWTVTIPLKGTIQTLWSATWSLSGSDKLIASGLNWNKTLEPNGTTEFGFCANY
>Mature_638_residues
SVSLLAGGLFSTSYVYAEAHVDNPFVDATSYLNPDYSKDIDTSITKVSDVSLKEKMETIKHYPTGVWLDTIDAVKGGAKN
PGRLNLTGHLDAALAQKKGNTPITATFVIYDIPGRDCHALASNGELPLNSASLERYKREYIDTIASIFSNPKYKDIRIVN
IIEPDSLPNLITNLSTPSCAKAKNTGIYEEGIKYALNKFSEIPNVYNYMDIGHAGWLGWDTNRIPAVSLYTKVIQSTTAG
FASVNGFATNTANTTPLIEPNLPNADLNIGGQPIRSSKFYDWNRYFDEMDYSETLYNDFIAAGWPSSIGFIIDTGRNGWG
GSQRPTSAFGNDINSYVNSGRIDRRNHRGNWCNQQDAGIGLPPTVTPGGHVDAFQWIKPPGYSDGSSSLIPNDQGKGFDR
YCDPTFTTPDGVLTGALPDAPLSGDWFHAQFVKLINNAYPDISRTPLPSSGSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
SSSSSSSSGSSSSSGSSSSSGSSSSSGSTSSSGSTSSSGSTSSSGSTSSSGSSSGTGFNPGAGFNPGAGSDPTKNPITSS
ITVDSDWYTGYCERVKVTNTGSSRSNWTVTIPLKGTIQTLWSATWSLSGSDKLIASGLNWNKTLEPNGTTEFGFCANY

Specific function: This enzyme hydrolyzes 1,4-beta-D-glucosidic linkages of cellulose. Weak activity against carboxymethylcellulose, bacterial microcrystalline cellulose and barley beta-glucan. Has also weak endoglucanase activity. Hydrolyzes glucosidic bonds with inversion

COG id: COG5297

COG function: function code G; Cellobiohydrolase A (1,4-beta-cellobiosidase A)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 3 fibronectin type-III domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016288
- InterPro:   IPR008965
- InterPro:   IPR012291
- InterPro:   IPR018366
- InterPro:   IPR001919
- InterPro:   IPR008957
- InterPro:   IPR003961
- InterPro:   IPR001524
- InterPro:   IPR013783 [H]

Pfam domain/function: PF00553 CBM_2; PF00041 fn3; PF01341 Glyco_hydro_6 [H]

EC number: =3.2.1.91 [H]

Molecular weight: Translated: 67466; Mature: 67334

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSLLAGGLFSTSYVYAEAHVDNPFVDATSYLNPDYSKDIDTSITKVSDVSLKEKMETI
CCCEEEECCHHHCEEEEEEECCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
KHYPTGVWLDTIDAVKGGAKNPGRLNLTGHLDAALAQKKGNTPITATFVIYDIPGRDCHA
HHCCCCEEEHHHHHHCCCCCCCCEEEEECCHHHHHHHHCCCCCEEEEEEEEECCCCCHHH
LASNGELPLNSASLERYKREYIDTIASIFSNPKYKDIRIVNIIEPDSLPNLITNLSTPSC
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHCCCCCCH
AKAKNTGIYEEGIKYALNKFSEIPNVYNYMDIGHAGWLGWDTNRIPAVSLYTKVIQSTTA
HHHCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GFASVNGFATNTANTTPLIEPNLPNADLNIGGQPIRSSKFYDWNRYFDEMDYSETLYNDF
CHHCCCCEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHH
IAAGWPSSIGFIIDTGRNGWGGSQRPTSAFGNDINSYVNSGRIDRRNHRGNWCNQQDAGI
HHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
GLPPTVTPGGHVDAFQWIKPPGYSDGSSSLIPNDQGKGFDRYCDPTFTTPDGVLTGALPD
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
APLSGDWFHAQFVKLINNAYPDISRTPLPSSGSSSSSSSSSSSSSSSSSSSSSSSSSSSS
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSSSSSSSSGSSSSSGSSSSSGSSSSSGSTSSSGSTSSSGSTSSSGSTSSSGSSSGTGFN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PGAGFNPGAGSDPTKNPITSSITVDSDWYTGYCERVKVTNTGSSRSNWTVTIPLKGTIQT
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEECCCCCCCCEEEEEECCHHHHH
LWSATWSLSGSDKLIASGLNWNKTLEPNGTTEFGFCANY
HHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCEEECC
>Mature Secondary Structure 
SVSLLAGGLFSTSYVYAEAHVDNPFVDATSYLNPDYSKDIDTSITKVSDVSLKEKMETI
CCEEEECCHHHCEEEEEEECCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
KHYPTGVWLDTIDAVKGGAKNPGRLNLTGHLDAALAQKKGNTPITATFVIYDIPGRDCHA
HHCCCCEEEHHHHHHCCCCCCCCEEEEECCHHHHHHHHCCCCCEEEEEEEEECCCCCHHH
LASNGELPLNSASLERYKREYIDTIASIFSNPKYKDIRIVNIIEPDSLPNLITNLSTPSC
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHCCCCCCH
AKAKNTGIYEEGIKYALNKFSEIPNVYNYMDIGHAGWLGWDTNRIPAVSLYTKVIQSTTA
HHHCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GFASVNGFATNTANTTPLIEPNLPNADLNIGGQPIRSSKFYDWNRYFDEMDYSETLYNDF
CHHCCCCEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHH
IAAGWPSSIGFIIDTGRNGWGGSQRPTSAFGNDINSYVNSGRIDRRNHRGNWCNQQDAGI
HHCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
GLPPTVTPGGHVDAFQWIKPPGYSDGSSSLIPNDQGKGFDRYCDPTFTTPDGVLTGALPD
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
APLSGDWFHAQFVKLINNAYPDISRTPLPSSGSSSSSSSSSSSSSSSSSSSSSSSSSSSS
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSSSSSSSSGSSSSSGSSSSSGSSSSSGSTSSSGSTSSSGSTSSSGSTSSSGSSSGTGFN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PGAGFNPGAGSDPTKNPITSSITVDSDWYTGYCERVKVTNTGSSRSNWTVTIPLKGTIQT
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEECCCCCCCCEEEEEECCHHHHH
LWSATWSLSGSDKLIASGLNWNKTLEPNGTTEFGFCANY
HHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8065260; 8458833 [H]