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The map label for this gene is clpX

Identifier: 182681029

GI number: 182681029

Start: 565313

End: 566593

Strand: Direct

Name: clpX

Synonym: XfasM23_0468

Alternate gene names: 182681029

Gene position: 565313-566593 (Clockwise)

Preceding gene: 182681028

Following gene: 182681030

Centisome position: 22.29

GC content: 46.06

Gene sequence:

>1281_bases
ATGAGCGAAGACCGGCAAAGCCGTTCTGGTGACGGAAATAAGATTCTTTACTGCTCATTCTGCGGTAAAAGCCAGCGTGA
GGTTCGCAAGCTGATCGCAGGTCCAAGCGTATTCATTTGTGATGAATGCGTTGAGTTGTGTAACGATATTATTCGCGAGG
AACTGGAAGAGAAGTCGCAATCTGCGCGTTCCAGTTTGCCTAAGCCCAAGGAGATACTTGAGGTTTTGGATCAGTATGTC
ATTGGCCAGCAGCGTGCTAAGAGGACTCTTGCTGTAGCCGTCTACAATCATTATAAACGGATCGAAAGTCGGCATAAGAA
TGACGACATCGAATTGGCTAAATCTAATATTTTGTTGGTTGGCCCAACAGGCTCCGGCAAGACATTGCTTGCCGAGACAT
TGGCGCGTTTGCTGAATGTGCCTTTCACGATTGCCGATGCAACCACATTGACTGAGGCTGGCTATGTTGGTGAGGACGTG
GAGAATATTATTCAGAAGTTGTTACATAAGTGTGATTACGACGTTGAAAAGGCGCAACATGGGATCGTCTACATTGATGA
AATAGATAAGATTTCCCGTAAGAGTGAGAATCCATCAATTACCCGAGATGTTTCTGGTGAGGGTGTGCAGCAGGCATTGC
TGAAATTGATAGAAGGTACGGTTGCTTCTGTGCCTCCTCAGGGTGGTCGCAAGCATCCACAGCAGGAATTCCTGCAGGTC
GATACCAAAAATATTTTATTCATCTGTGGCGGTGCTTTTGCTGGTCTAGATAAAGTGATCCAACAGCGTTGCAATGAAGT
TGGTGGTATTGGCTTTGGTGTTAAGGTCAAAAGCTCAGAGAGTAAGCGCGATGTTGGTAAGGTACTAGCTGGTGTCGAGC
CAGAGGACCTGATTAAGTTTGGGTTAATCCCTGAATTCGTTGGGCGATTGCCAGTTGTAGCTACACTTGATGAGCTGGAT
GAGTCGGCTTTGGTTAAAATTTTAACCGAGCCAAAGAACGCTATTACAAAGCAGTTCAAAAAGCTGTTTGAGATGGAGAA
CGTAGAGTTGGAGTTCCGTCAGGACGCGCTTTCAGCAGTGGCTAGGAAAGCTCTTAAGCGCAAGACTGGTGCGCGGGGTC
TCCGTACTATTGTTGAGTTGGTTCTGCTGGATACCATGTACGAACTTCCTTCTCAGGAAGGTATTAGTAAGGTTGTTGTC
GATGAATCGGTTATTGAAAATAAATCTGAGCCTTATCTGATTTATCAAACGATGCCTGCAAAGGTTGCTTCCGGCGAATG
A

Upstream 100 bases:

>100_bases
TTAGTTGCAATGGAATCTGTGATGTTGTTCTGCTCATATTGTGGTATTGTCATGGGTAAATCTGCATATATACCTACCGC
GCTAATCGGGTAACAAAAGC

Downstream 100 bases:

>100_bases
ATGCTCTTTATAGCGTTGCGGCTATTCGTATAACTGACACTGAGAGTCGACGGTTTTAAAGAAAGCTCTTGTAAGCTTGC
CCGAATGGCCTCATAACGGG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSEDRQSRSGDGNKILYCSFCGKSQREVRKLIAGPSVFICDECVELCNDIIREELEEKSQSARSSLPKPKEILEVLDQYV
IGQQRAKRTLAVAVYNHYKRIESRHKNDDIELAKSNILLVGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDV
ENIIQKLLHKCDYDVEKAQHGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTKNILFICGGAFAGLDKVIQQRCNEVGGIGFGVKVKSSESKRDVGKVLAGVEPEDLIKFGLIPEFVGRLPVVATLDELD
ESALVKILTEPKNAITKQFKKLFEMENVELEFRQDALSAVARKALKRKTGARGLRTIVELVLLDTMYELPSQEGISKVVV
DESVIENKSEPYLIYQTMPAKVASGE

Sequences:

>Translated_426_residues
MSEDRQSRSGDGNKILYCSFCGKSQREVRKLIAGPSVFICDECVELCNDIIREELEEKSQSARSSLPKPKEILEVLDQYV
IGQQRAKRTLAVAVYNHYKRIESRHKNDDIELAKSNILLVGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDV
ENIIQKLLHKCDYDVEKAQHGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTKNILFICGGAFAGLDKVIQQRCNEVGGIGFGVKVKSSESKRDVGKVLAGVEPEDLIKFGLIPEFVGRLPVVATLDELD
ESALVKILTEPKNAITKQFKKLFEMENVELEFRQDALSAVARKALKRKTGARGLRTIVELVLLDTMYELPSQEGISKVVV
DESVIENKSEPYLIYQTMPAKVASGE
>Mature_425_residues
SEDRQSRSGDGNKILYCSFCGKSQREVRKLIAGPSVFICDECVELCNDIIREELEEKSQSARSSLPKPKEILEVLDQYVI
GQQRAKRTLAVAVYNHYKRIESRHKNDDIELAKSNILLVGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVE
NIIQKLLHKCDYDVEKAQHGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVD
TKNILFICGGAFAGLDKVIQQRCNEVGGIGFGVKVKSSESKRDVGKVLAGVEPEDLIKFGLIPEFVGRLPVVATLDELDE
SALVKILTEPKNAITKQFKKLFEMENVELEFRQDALSAVARKALKRKTGARGLRTIVELVLLDTMYELPSQEGISKVVVD
ESVIENKSEPYLIYQTMPAKVASGE

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=349, Percent_Identity=52.7220630372493, Blast_Score=324, Evalue=9e-89,
Organism=Escherichia coli, GI1786642, Length=427, Percent_Identity=73.3021077283372, Blast_Score=635, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=46.6019417475728, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=319, Percent_Identity=46.0815047021944, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI71982905, Length=319, Percent_Identity=46.0815047021944, Blast_Score=272, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI71988663, Length=417, Percent_Identity=38.3693045563549, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=250, Percent_Identity=40.4, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=436, Percent_Identity=39.2201834862385, Blast_Score=279, Evalue=6e-76,
Organism=Drosophila melanogaster, GI24648289, Length=322, Percent_Identity=46.583850931677, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24648291, Length=322, Percent_Identity=46.583850931677, Blast_Score=293, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_XYLF2 (B2I8K4)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829189.1
- ProteinModelPortal:   B2I8K4
- GeneID:   6201873
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0468
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 47130; Mature: 46999

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDRQSRSGDGNKILYCSFCGKSQREVRKLIAGPSVFICDECVELCNDIIREELEEKSQ
CCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHH
SARSSLPKPKEILEVLDQYVIGQQRAKRTLAVAVYNHYKRIESRHKNDDIELAKSNILLV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEE
GPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLHKCDYDVEKAQH
ECCCCCCHHHHHHHHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCC
GIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
CEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHH
DTKNILFICGGAFAGLDKVIQQRCNEVGGIGFGVKVKSSESKRDVGKVLAGVEPEDLIKF
CCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHH
GLIPEFVGRLPVVATLDELDESALVKILTEPKNAITKQFKKLFEMENVELEFRQDALSAV
CCCHHHHCCCCHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ARKALKRKTGARGLRTIVELVLLDTMYELPSQEGISKVVVDESVIENKSEPYLIYQTMPA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCC
KVASGE
CCCCCC
>Mature Secondary Structure 
SEDRQSRSGDGNKILYCSFCGKSQREVRKLIAGPSVFICDECVELCNDIIREELEEKSQ
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHH
SARSSLPKPKEILEVLDQYVIGQQRAKRTLAVAVYNHYKRIESRHKNDDIELAKSNILLV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEE
GPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLHKCDYDVEKAQH
ECCCCCCHHHHHHHHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCC
GIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
CEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHH
DTKNILFICGGAFAGLDKVIQQRCNEVGGIGFGVKVKSSESKRDVGKVLAGVEPEDLIKF
CCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHH
GLIPEFVGRLPVVATLDELDESALVKILTEPKNAITKQFKKLFEMENVELEFRQDALSAV
CCCHHHHCCCCHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ARKALKRKTGARGLRTIVELVLLDTMYELPSQEGISKVVVDESVIENKSEPYLIYQTMPA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCC
KVASGE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA