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The map label for this gene is lolC [H]

Identifier: 182680910

GI number: 182680910

Start: 444820

End: 446061

Strand: Direct

Name: lolC [H]

Synonym: XfasM23_0348

Alternate gene names: 182680910

Gene position: 444820-446061 (Clockwise)

Preceding gene: 182680909

Following gene: 182680911

Centisome position: 17.54

GC content: 53.3

Gene sequence:

>1242_bases
ATGTTTAATCCGCTTTCTGTTGCGATCGGTTTGCGTTATCTGCGTGCCAAGCGGCGCAATGGTTTCATCTCGTTTATTTC
AATGGCTTCCATCCTGGGCATTGCTCTGGGAGTGACTGTCTTGATTACTACCTTGGCAGTGATGAGCGGCTTTCAGAAAG
AGATTCGTGACCGATTGTTGCAAATGTCTGCACACGCAACGGTGAGTGCGCAGGGAGCACCGATGCATGATTGGCAGCAT
GCAGTTGCGTTGGCGATGACTGATCCCCGCGTCGCTGGTGCTGCGCCGTACATCGAGAGTGAAGCGTTGCTCCAGGGGGA
GCGTCATCAGCCTGCGATGATGCGTGGCATCGTGCCCAACCAGGAAACTAAGGTTTCGGTGCTGGCGCAGAAATTGAAGG
TTGGTTCAATTGATAGTCTCAAGCCCGGTGAGTACAACATCTTGCTTGGTAAGGAGTTAGCCTTGTGGTTAGGCGTTGAT
GTCGGCGACAGCGTGATCGTGCTCCTCAGTCAAACTCAGACCACTCCAGTGGGGACGATGCCACGGATGAAGCGCTTCAC
CGTCAGTGGCTTGTTTGAAGTCGGCTACAACGAAATCGACCGTGGCTTAGCGGTGGTCAATATGGAGGATATGCAGAAGA
TCATGCGGATGGACGGTGTGACCGGCGTGCGTTTGAAATTGCACGATATGGATCATGCCTGGGACGTTGCGAGTGACTTG
GCGGTCCGCCTGAATGGCCCCTATCTGGTGAGCGACTGGACACGCGAAAATGCCAATCTGTACAGTTCATTGAAGATGGA
AAAAACGGTGATGGGCATTTTGCTCTCCCTGATCATCGCGATGGGCGCCTTCAACTTGGTGTCCTCGCAGGTGATGTTGG
TCACTGATAAGCAAGCCGATATCGCCATCTTGCGCACCTTGGGTTTGTCGCCAGCAGGGGTGATGCGAGTATTTATGGTG
CAGGGGTCGTTGATTGGCATCATCGGTACCCTCTCTGGCGTGATCGGTGGTGTGGTGCTGACTTGGAATCTGGAGCGAAT
CCTGAAATTGATTGAATCCACGTTCAACATTACCCTGCTTCCGGAGGATGTGTATTACATCACTGGCCTGCCGACCGATA
TGCAGTTCCCTGATGTGGTAGTGATTACTCTGATGGCGTTGGCAATGAGTTTCATTGCCACCTTGTACCCGGCGTGGCGT
GCCGCCAGGATTCAGCCAGCAGAGGCGCTGCGTTATGAATGA

Upstream 100 bases:

>100_bases
GCCATGCGGCGTCAGTTGCGTCTGGTCATGCAAGCGCGTCAGCTTTCGTCCCAGGTGCCGTCAATGGCACCATAGCCGCT
TCACTATCAGTTGGGTCTCA

Downstream 100 bases:

>100_bases
GCGCAGTACTCCCCAGGCATTGACCGGCCCGGTGATTCGAGCCGAGTCCCTTGGAAAAACCTATTCTGAGGGTAAGTTAC
TGACCCAAGTGTTTGATGGG

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MFNPLSVAIGLRYLRAKRRNGFISFISMASILGIALGVTVLITTLAVMSGFQKEIRDRLLQMSAHATVSAQGAPMHDWQH
AVALAMTDPRVAGAAPYIESEALLQGERHQPAMMRGIVPNQETKVSVLAQKLKVGSIDSLKPGEYNILLGKELALWLGVD
VGDSVIVLLSQTQTTPVGTMPRMKRFTVSGLFEVGYNEIDRGLAVVNMEDMQKIMRMDGVTGVRLKLHDMDHAWDVASDL
AVRLNGPYLVSDWTRENANLYSSLKMEKTVMGILLSLIIAMGAFNLVSSQVMLVTDKQADIAILRTLGLSPAGVMRVFMV
QGSLIGIIGTLSGVIGGVVLTWNLERILKLIESTFNITLLPEDVYYITGLPTDMQFPDVVVITLMALAMSFIATLYPAWR
AARIQPAEALRYE

Sequences:

>Translated_413_residues
MFNPLSVAIGLRYLRAKRRNGFISFISMASILGIALGVTVLITTLAVMSGFQKEIRDRLLQMSAHATVSAQGAPMHDWQH
AVALAMTDPRVAGAAPYIESEALLQGERHQPAMMRGIVPNQETKVSVLAQKLKVGSIDSLKPGEYNILLGKELALWLGVD
VGDSVIVLLSQTQTTPVGTMPRMKRFTVSGLFEVGYNEIDRGLAVVNMEDMQKIMRMDGVTGVRLKLHDMDHAWDVASDL
AVRLNGPYLVSDWTRENANLYSSLKMEKTVMGILLSLIIAMGAFNLVSSQVMLVTDKQADIAILRTLGLSPAGVMRVFMV
QGSLIGIIGTLSGVIGGVVLTWNLERILKLIESTFNITLLPEDVYYITGLPTDMQFPDVVVITLMALAMSFIATLYPAWR
AARIQPAEALRYE
>Mature_413_residues
MFNPLSVAIGLRYLRAKRRNGFISFISMASILGIALGVTVLITTLAVMSGFQKEIRDRLLQMSAHATVSAQGAPMHDWQH
AVALAMTDPRVAGAAPYIESEALLQGERHQPAMMRGIVPNQETKVSVLAQKLKVGSIDSLKPGEYNILLGKELALWLGVD
VGDSVIVLLSQTQTTPVGTMPRMKRFTVSGLFEVGYNEIDRGLAVVNMEDMQKIMRMDGVTGVRLKLHDMDHAWDVASDL
AVRLNGPYLVSDWTRENANLYSSLKMEKTVMGILLSLIIAMGAFNLVSSQVMLVTDKQADIAILRTLGLSPAGVMRVFMV
QGSLIGIIGTLSGVIGGVVLTWNLERILKLIESTFNITLLPEDVYYITGLPTDMQFPDVVVITLMALAMSFIATLYPAWR
AARIQPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=417, Percent_Identity=36.6906474820144, Blast_Score=224, Evalue=6e-60,
Organism=Escherichia coli, GI1787362, Length=409, Percent_Identity=34.4743276283619, Blast_Score=222, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45235; Mature: 45235

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNPLSVAIGLRYLRAKRRNGFISFISMASILGIALGVTVLITTLAVMSGFQKEIRDRLL
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMSAHATVSAQGAPMHDWQHAVALAMTDPRVAGAAPYIESEALLQGERHQPAMMRGIVPN
HHHHCCEEECCCCCCCCHHHEEEEEECCCCCCCCCCCCCCHHHHCCCCCCCHHHHCCCCC
QETKVSVLAQKLKVGSIDSLKPGEYNILLGKELALWLGVDVGDSVIVLLSQTQTTPVGTM
CCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCEEEEEECCCCCCCCCC
PRMKRFTVSGLFEVGYNEIDRGLAVVNMEDMQKIMRMDGVTGVRLKLHDMDHAWDVASDL
CHHHHHHHHHHHHHCHHHHHCCEEEEEHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCC
AVRLNGPYLVSDWTRENANLYSSLKMEKTVMGILLSLIIAMGAFNLVSSQVMLVTDKQAD
EEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
IAILRTLGLSPAGVMRVFMVQGSLIGIIGTLSGVIGGVVLTWNLERILKLIESTFNITLL
HHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECHHHHHHHHHCCCCEEEE
PEDVYYITGLPTDMQFPDVVVITLMALAMSFIATLYPAWRAARIQPAEALRYE
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure
MFNPLSVAIGLRYLRAKRRNGFISFISMASILGIALGVTVLITTLAVMSGFQKEIRDRLL
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMSAHATVSAQGAPMHDWQHAVALAMTDPRVAGAAPYIESEALLQGERHQPAMMRGIVPN
HHHHCCEEECCCCCCCCHHHEEEEEECCCCCCCCCCCCCCHHHHCCCCCCCHHHHCCCCC
QETKVSVLAQKLKVGSIDSLKPGEYNILLGKELALWLGVDVGDSVIVLLSQTQTTPVGTM
CCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCEEEEEECCCCCCCCCC
PRMKRFTVSGLFEVGYNEIDRGLAVVNMEDMQKIMRMDGVTGVRLKLHDMDHAWDVASDL
CHHHHHHHHHHHHHCHHHHHCCEEEEEHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCC
AVRLNGPYLVSDWTRENANLYSSLKMEKTVMGILLSLIIAMGAFNLVSSQVMLVTDKQAD
EEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
IAILRTLGLSPAGVMRVFMVQGSLIGIIGTLSGVIGGVVLTWNLERILKLIESTFNITLL
HHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECHHHHHHHHHCCCCEEEE
PEDVYYITGLPTDMQFPDVVVITLMALAMSFIATLYPAWRAARIQPAEALRYE
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]