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The map label for this gene is tadA [H]

Identifier: 182680863

GI number: 182680863

Start: 385819

End: 386316

Strand: Reverse

Name: tadA [H]

Synonym: XfasM23_0300

Alternate gene names: 182680863

Gene position: 386316-385819 (Counterclockwise)

Preceding gene: 182680864

Following gene: 182680844

Centisome position: 15.24

GC content: 61.65

Gene sequence:

>498_bases
ATGACTGCCCCCCCCCCCGTCTTGCCAGAACACACCCACTGGATGCGCCATGCACTGACCCTGGCCCACCGTGCAGCAAC
AGAATTCGATGAAATCCCCGTCGGCGCTGTACTAATCAGCCCCGAAGGGACCCTACTCGGCGAAGGATGCAACTACAACA
TCACCAGCCACGACCCCAGCGCACACGCCGAAATCATGGCACTGCGCGCTGCGGGCCACCAACTGCGCAACCATCGCATG
CCTGGCTGCACCCTCTACGTCACCCTGGAACCTTGCCTGATGTGCGCCATGGCCATCATCCATGCACGCATCGCACACCT
CATCTACGCCGCCGCAGACCCCAAAACAGGCGCCTGCGGCAGCACATTCGACATCCTCAACGACCCACGCCACAACCACC
ATGTCCACGTCTACGGCGGCCTCCTTGCCGAAGAAGCCTCACGCCGCCTGACAAACTACTTCCGTACCAAACGCGGCCAA
CCGCCACTGCCACAATAA

Upstream 100 bases:

>100_bases
CGCCGCGACGCCGAAGGCATCGAACACCACGTTAGCGAAACAACATTGGCCGCCTTTAGAACATTCCTACAACGCCACAG
CGACACCACCTGAAACCAAC

Downstream 100 bases:

>100_bases
CCCCCCTCCCCCTGCGCGACAGCACCACCAACCATCCGATACACCACAACACAGCATCCATCCACCGATCAAACACCCCT
CTCACCCCCCACGCGCACCT

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTAPPPVLPEHTHWMRHALTLAHRAATEFDEIPVGAVLISPEGTLLGEGCNYNITSHDPSAHAEIMALRAAGHQLRNHRM
PGCTLYVTLEPCLMCAMAIIHARIAHLIYAAADPKTGACGSTFDILNDPRHNHHVHVYGGLLAEEASRRLTNYFRTKRGQ
PPLPQ

Sequences:

>Translated_165_residues
MTAPPPVLPEHTHWMRHALTLAHRAATEFDEIPVGAVLISPEGTLLGEGCNYNITSHDPSAHAEIMALRAAGHQLRNHRM
PGCTLYVTLEPCLMCAMAIIHARIAHLIYAAADPKTGACGSTFDILNDPRHNHHVHVYGGLLAEEASRRLTNYFRTKRGQ
PPLPQ
>Mature_164_residues
TAPPPVLPEHTHWMRHALTLAHRAATEFDEIPVGAVLISPEGTLLGEGCNYNITSHDPSAHAEIMALRAAGHQLRNHRMP
GCTLYVTLEPCLMCAMAIIHARIAHLIYAAADPKTGACGSTFDILNDPRHNHHVHVYGGLLAEEASRRLTNYFRTKRGQP
PLPQ

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=161, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI145693172, Length=150, Percent_Identity=52.6666666666667, Blast_Score=158, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17541138, Length=152, Percent_Identity=31.5789473684211, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17554608, Length=99, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17555996, Length=131, Percent_Identity=29.7709923664122, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322425, Length=168, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 18131; Mature: 18000

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPPPVLPEHTHWMRHALTLAHRAATEFDEIPVGAVLISPEGTLLGEGCNYNITSHDPS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCCCCCCCCCCCC
AHAEIMALRAAGHQLRNHRMPGCTLYVTLEPCLMCAMAIIHARIAHLIYAAADPKTGACG
HHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
STFDILNDPRHNHHVHVYGGLLAEEASRRLTNYFRTKRGQPPLPQ
CCHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TAPPPVLPEHTHWMRHALTLAHRAATEFDEIPVGAVLISPEGTLLGEGCNYNITSHDPS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCCCCCCCCCCCC
AHAEIMALRAAGHQLRNHRMPGCTLYVTLEPCLMCAMAIIHARIAHLIYAAADPKTGACG
HHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
STFDILNDPRHNHHVHVYGGLLAEEASRRLTNYFRTKRGQPPLPQ
CCHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]