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The map label for this gene is nuoC [H]

Identifier: 182680807

GI number: 182680807

Start: 318601

End: 319287

Strand: Direct

Name: nuoC [H]

Synonym: XfasM23_0242

Alternate gene names: 182680807

Gene position: 318601-319287 (Clockwise)

Preceding gene: 182680806

Following gene: 182680808

Centisome position: 12.56

GC content: 55.6

Gene sequence:

>687_bases
GTGGCCCAGCCGCGTGGTGAGATCAGTCTTGATGTGCCCGTGGTTGAGTGGTGTGCCGTTTGCAAAGCGTTGCGTGACGA
GTTCGACTTTGAACAGTTATCCGATCTTTGCGGAGTGGACTATCTTGGCTATGGCAATGCGGAGTGGGACACCACTGATG
TATCCGCGCAGGGGTTCAGCCGTGGCGTTGCTGGTAAGGCGGTTGGCCGCTTTGCTTGGGGTGAGTTTCCAAGTGCAGGC
AGCAATGATGGTACTCAGCCGTGGGATGTTCCGCAGGAGCGCTTTGCAGTGCTCGCGCACCTCATTTCTTATCGGCATAA
CCGGCGTTTGCGGGTGCGTTGTTTTGCTTCCAATGATGCGTTACCGATCGTCGCTTCGCTGACGGACGTATGGCCTGGGG
TGAATTGGTTCGAGCGTGAGGCATTTGATTTGTTCGGTATTGTGTTCGAGGGGCACCCTGATTTGCGTCGCATCCTGACG
GACTATGGATTCATTGGTCATCCCTTTCGTAAGGATTTTCCGCTGACCGGCAACGTTGAGGTGCGTTACGACGAGGAAAA
GAAGCGTGTTGTGTATGTCCCGGTCACCTCGGTTGAGCCGCGTGTCAGTGTTCCGCGGGTGATTCGTGATGATCCCCGCT
TTGGGGCTGCAGCGGGCGAATCTACTCATTCGGAGACTGTTAAGTGA

Upstream 100 bases:

>100_bases
ACTGAATAGCCAACTATTGAGCAGCCAAGTCCACATGGCAGAACAAACTCTTTCTTTCGTTGATTGTCTAATGTCGCGCT
TCCCAACGGTTCGGGTCTCC

Downstream 100 bases:

>100_bases
ATCAGATTCGCCAGGCGCCTGCGGCTTCTGCCAGCAATGCTACTGAATCCAAGCAGGAGATTCGTAATTACACGATGAAC
TTCGGTCCACAGCATCCTGC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MAQPRGEISLDVPVVEWCAVCKALRDEFDFEQLSDLCGVDYLGYGNAEWDTTDVSAQGFSRGVAGKAVGRFAWGEFPSAG
SNDGTQPWDVPQERFAVLAHLISYRHNRRLRVRCFASNDALPIVASLTDVWPGVNWFEREAFDLFGIVFEGHPDLRRILT
DYGFIGHPFRKDFPLTGNVEVRYDEEKKRVVYVPVTSVEPRVSVPRVIRDDPRFGAAAGESTHSETVK

Sequences:

>Translated_228_residues
MAQPRGEISLDVPVVEWCAVCKALRDEFDFEQLSDLCGVDYLGYGNAEWDTTDVSAQGFSRGVAGKAVGRFAWGEFPSAG
SNDGTQPWDVPQERFAVLAHLISYRHNRRLRVRCFASNDALPIVASLTDVWPGVNWFEREAFDLFGIVFEGHPDLRRILT
DYGFIGHPFRKDFPLTGNVEVRYDEEKKRVVYVPVTSVEPRVSVPRVIRDDPRFGAAAGESTHSETVK
>Mature_227_residues
AQPRGEISLDVPVVEWCAVCKALRDEFDFEQLSDLCGVDYLGYGNAEWDTTDVSAQGFSRGVAGKAVGRFAWGEFPSAGS
NDGTQPWDVPQERFAVLAHLISYRHNRRLRVRCFASNDALPIVASLTDVWPGVNWFEREAFDLFGIVFEGHPDLRRILTD
YGFIGHPFRKDFPLTGNVEVRYDEEKKRVVYVPVTSVEPRVSVPRVIRDDPRFGAAAGESTHSETVK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=109, Percent_Identity=56.8807339449541, Blast_Score=125, Evalue=3e-29,
Organism=Escherichia coli, GI145693162, Length=86, Percent_Identity=46.5116279069767, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71990788, Length=108, Percent_Identity=56.4814814814815, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32563621, Length=108, Percent_Identity=56.4814814814815, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24656494, Length=109, Percent_Identity=54.1284403669725, Blast_Score=120, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 25626; Mature: 25495

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPRGEISLDVPVVEWCAVCKALRDEFDFEQLSDLCGVDYLGYGNAEWDTTDVSAQGFS
CCCCCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
RGVAGKAVGRFAWGEFPSAGSNDGTQPWDVPQERFAVLAHLISYRHNRRLRVRCFASNDA
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCC
LPIVASLTDVWPGVNWFEREAFDLFGIVFEGHPDLRRILTDYGFIGHPFRKDFPLTGNVE
CCHHHHHHHHCCCCCHHHHHHHHHEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCEE
VRYDEEKKRVVYVPVTSVEPRVSVPRVIRDDPRFGAAAGESTHSETVK
EEECCCCCEEEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AQPRGEISLDVPVVEWCAVCKALRDEFDFEQLSDLCGVDYLGYGNAEWDTTDVSAQGFS
CCCCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
RGVAGKAVGRFAWGEFPSAGSNDGTQPWDVPQERFAVLAHLISYRHNRRLRVRCFASNDA
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCC
LPIVASLTDVWPGVNWFEREAFDLFGIVFEGHPDLRRILTDYGFIGHPFRKDFPLTGNVE
CCHHHHHHHHCCCCCHHHHHHHHHEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCEE
VRYDEEKKRVVYVPVTSVEPRVSVPRVIRDDPRFGAAAGESTHSETVK
EEECCCCCEEEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA