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The map label for this gene is nuoA [H]

Identifier: 182680805

GI number: 182680805

Start: 317531

End: 317938

Strand: Direct

Name: nuoA [H]

Synonym: XfasM23_0240

Alternate gene names: 182680805

Gene position: 317531-317938 (Clockwise)

Preceding gene: 182680804

Following gene: 182680806

Centisome position: 12.52

GC content: 46.57

Gene sequence:

>408_bases
ATGCCTATGTCTTCCTATTTTATGGGGGCATCGGTTAGAAAGAGAATCGCTGTGCTGGCCGAATATTTGCCGATTCTGAT
TTTTCTGGTTGTGGCTACCGGTATTGGTCTTGCATTGATATTGATTGGCAGGTTCCTCGGTCCGCATCGCCCTGATTCCG
AAAAGCTCTCCTCATATGAGTGTGGGTTTTCGGCTTTCGAAGACGCACGGATGAAGTTCGATGTGCGTTATTACTTGATT
GCGATTCAATTCATTGTCTTCGACTTAGAAATCATCTTCATCGTGCCTTGGACTCAGGTGTTCATGGATATTGGCGCGCG
TTCGCTTGTCACGATGGGGCTATTTGTCGGGATGCTGTTTCTTGGTTTTATATACGTATGGAAGAAGGGAGCGCTGGAAT
GGGAGTAA

Upstream 100 bases:

>100_bases
TAGGGGTTCGAGTCCCCTCTTGGGCACCATGTTTGCTTGTTTGTTTTTGCGCGTCGTGATCATCGCCAGGTAGAATCTTG
TTGTATCCCCTCCCCAATGC

Downstream 100 bases:

>100_bases
TTCAGGCTATTGATCGTCTGATGACTAATCCGATCCCTGATGGTCAGGTGGATGACATTCTACGGCCGCAGGGGGAGAGT
CCACTGTTGCAAAAGGGCTA

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MPMSSYFMGASVRKRIAVLAEYLPILIFLVVATGIGLALILIGRFLGPHRPDSEKLSSYECGFSAFEDARMKFDVRYYLI
AIQFIVFDLEIIFIVPWTQVFMDIGARSLVTMGLFVGMLFLGFIYVWKKGALEWE

Sequences:

>Translated_135_residues
MPMSSYFMGASVRKRIAVLAEYLPILIFLVVATGIGLALILIGRFLGPHRPDSEKLSSYECGFSAFEDARMKFDVRYYLI
AIQFIVFDLEIIFIVPWTQVFMDIGARSLVTMGLFVGMLFLGFIYVWKKGALEWE
>Mature_134_residues
PMSSYFMGASVRKRIAVLAEYLPILIFLVVATGIGLALILIGRFLGPHRPDSEKLSSYECGFSAFEDARMKFDVRYYLIA
IQFIVFDLEIIFIVPWTQVFMDIGARSLVTMGLFVGMLFLGFIYVWKKGALEWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=124, Percent_Identity=29.0322580645161, Blast_Score=71, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 15407; Mature: 15275

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMSSYFMGASVRKRIAVLAEYLPILIFLVVATGIGLALILIGRFLGPHRPDSEKLSSYE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
CGFSAFEDARMKFDVRYYLIAIQFIVFDLEIIFIVPWTQVFMDIGARSLVTMGLFVGMLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHCHHHHHHHHHHHHHHH
LGFIYVWKKGALEWE
HHHHHHHHCCCCCCC
>Mature Secondary Structure 
PMSSYFMGASVRKRIAVLAEYLPILIFLVVATGIGLALILIGRFLGPHRPDSEKLSSYE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
CGFSAFEDARMKFDVRYYLIAIQFIVFDLEIIFIVPWTQVFMDIGARSLVTMGLFVGMLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHCHHHHHHHHHHHHHHH
LGFIYVWKKGALEWE
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA