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The map label for this gene is algC [H]

Identifier: 182680684

GI number: 182680684

Start: 151926

End: 154469

Strand: Direct

Name: algC [H]

Synonym: XfasM23_0113

Alternate gene names: 182680684

Gene position: 151926-154469 (Clockwise)

Preceding gene: 182680683

Following gene: 182680687

Centisome position: 5.99

GC content: 52.0

Gene sequence:

>2544_bases
ATGAGCGTGACAATTGGAAACGAGTTGATTTTGCCGATGAAACGACGCCGGATTGCATTTCTTTTGGCGATGTTGTGTTT
GTTGCTGGCAGGGGTGTTTTGTTGGGGGGCGTACATACAGTGGCGCCAGAATGTGGTGCAGCAGAAGCTCGAGCAGGCAC
GTGATGGTGCTGTTGCGTCATTGCTTCAGGTGCTGTCTGCTCAGGTTAAGCAGTTGCAAAATGTGGTGCAGCGTCCGGCC
ATCGTACAGGTGCTGGGTGGAGGTGACGTCACGGCAGCAGCTGCAGCGGTTCGTGAGCAATTTCCAGGCACTGAGGATGT
ACAGGTTCTGACCGGCGATCTGAGTGCTGCTTATGCGGATGTGGCGCGCTCCGGTTATGCCCGCCTTGGGCTGATAGAGG
CGGCTCTTGGTGGTGATGGTGTGAAGGCATGGGTTGTACGTGACGGTACTCAGATTGGCTTGGGTATGGCTGTGATGGTC
AAGCTTGGCCAAGCTCCGGCGGTGGTCTATCTTCGCCTGCCGCTACGTGGCTTGATAAGTGTGTTGGATGCGATTGAGGT
GCCCAATAGCACTTACTTGGCATTGCGTCAGGGGAGTTATACGGTGGTCGAGCGCGGTAGCGCCGCGTTAGCCAGTGGTG
GTGAGGCATTGGCTAAACCGCTGGGTTGGGCTGACTTGCGTATGGCTGCCGCTGTGCCGCAGCTGGAAAACGTCCCTTTT
GATTTGGGATTGCTGCCATCTTTGATTGTGGTAGGGGTGTTTGCGCTAGTTGCGGCGGTCCTGTTGTTAGTTGCGGGTGG
GCATAGGATGCTACCCAGGCGTCACGGGCAAATGGCCGATGCAGAACAAGAACAGGTTACTTTGCGTGAAAGTGTGATGC
AGGAGGCGCCGGAGCGCGCGATCGTTTTGAATGACGAAAACAAGGAAAACAAGGAAAACAAGGAAAACAAGGAAAACAAG
GAAAACAAGGAAAACAAGGAAAACAAGGAAAACAAGGAAAACAAGGAAAACAAGGAAAACAAGGAAAACAAGGAAAACAA
GGAAAACAAGGAAAACAAGGAAAACAAGGAAAACAAGGAAAACAAGGAAAACAAGGAAAACAACGTTGCGTTGTCGTCGT
CGCTGCATCTTCAGTTCAATTTGGAAGCGGTGGTTCAACCTAGTCTTTTCCATGAAGACGATATCCACGGTGTGGTCCCT
AGCGAGTTGAACCCAGGTGTGGCGAAGTTGATCGGTCAAGCGATCGGCAGTGCGATGCAGGCCAAAGGTTTGAGTGACAT
TGTGATTGGCCGTGACGGCCGCGTGTCCAGTTCTGAGTTGTCCGCAGCATTAAGTGATGGTCTACGTCATGCCGGTTGCA
ATGTGGTAGACATCGGCTTGGTGCCGATCCCTGTAGTGTATTTCGCTGCCTGCCATCTTGGCGTTTGGAGTTGCGTTGCG
GTCACAGGGGGGCATCATCCTCATGATTACAACGGTTTCAAGATCGTGCTTGGTGGTGAGTCCTTATCCAGTGAGGCGAT
GAGCGATTTGTATCAGTGCATCACCAATGGTCGCTTATATGCGTCCGTTGACTCCGGCAGTTTGAGTGAGCGTGATGTGG
TTGACGATTACATTCAGCGTATTGCTGATGATGTGCAGTTGAATCGTCCGCTGAAGATTGTTGTTGATCCTGGTCACGGT
GCGGCTGAAGAGATCCTGTCACGTTTATTTAAGGCGATTGGTGCGGATCTGGTGTCACTGTACGGTGATATTGATGGTGT
TTCCCTTATTGTCCATCCTGATTCGGGCGAGCCAGGGAATCTGCAGAAGTTGATTCAGCGGGTTGAGCGGGCCGATGCCG
ATTTGGGTCTTGCTTTTGATGGGGATGCGGAAAGTCTCAGAGTGGTGACTCGAGAAGGTGAGGTCATTTTATCGGATAGC
GTGTTGATGTTGTTTGCGACGGATGTGCTACAGAGGAATCCGGGTGCTTTGGTGATCTATGATGCTGAATGTACTAGCAA
GTTGTCTGATTATGTATTGCGCAATGGCGGCAGCCCGTTGATGTGGAAGATAGGGCATTCCTCCATCAAAGCTAAGATGC
GCGAGACCGGTGCCGAGTTGGCTGGTGAAATGAGTGGCTATTTCTTCTTCAAAGAACGCTGGTATGGTTTTGAGGATGCT
CTGTATGCGGCGGCGCGTTTGCTGGAGATCTTAGCGCAGCGCGAGGATAATCCGTCTCAGGTGTTTGCTGCATTGCCCCA
TGCTTATTTCACTGCGCAAATGGAGCAGTCTGTCGAGGGTGATGCGCAGGCATGTGTACAGTCCTTTATTGAGGAAGTGC
AGCGTAGCGTTGAGGGCGGTGTGTTCGATGGTGCTCGTTTGTTCGCCTTTGATGGTTTGCGTGCTGATTTCACTGATGGT
TGGGGGCTAGTACGCGTTTCTGACACTGCATCTGCACTGGTGTTGCGTTTTGAGGCTGACACGCAGGCTGGATTGGAGCG
GATTCAGAGTGCATTCCGCACGCATCTGCAGGCATTACTACCCGGTCAGGTACTGGTGTTCTAA

Upstream 100 bases:

>100_bases
ATTGTGCGTGTAGTGCTTCAGGTAGTGGATACTTTTGTTGAAAGTGGGCGTGGAGCGGGTGGTTTTGGTCACACTGGCGT
GCGTTGACGGAGGAAGACAG

Downstream 100 bases:

>100_bases
ATCTTTTAATGTTTATGGTTCCGCGAGTGGTGAGGCATTTGCCTCACTGCTTTTCAATGCTCGGTAACGTTGTAAGGTTT
CTTCGATTTCTCCGCTAAGT

Product: phosphoglucomutase/phosphomannomutase subunit alpha/beta

Products: NA

Alternate protein names: PMM / PGM [H]

Number of amino acids: Translated: 847; Mature: 846

Protein sequence:

>847_residues
MSVTIGNELILPMKRRRIAFLLAMLCLLLAGVFCWGAYIQWRQNVVQQKLEQARDGAVASLLQVLSAQVKQLQNVVQRPA
IVQVLGGGDVTAAAAAVREQFPGTEDVQVLTGDLSAAYADVARSGYARLGLIEAALGGDGVKAWVVRDGTQIGLGMAVMV
KLGQAPAVVYLRLPLRGLISVLDAIEVPNSTYLALRQGSYTVVERGSAALASGGEALAKPLGWADLRMAAAVPQLENVPF
DLGLLPSLIVVGVFALVAAVLLLVAGGHRMLPRRHGQMADAEQEQVTLRESVMQEAPERAIVLNDENKENKENKENKENK
ENKENKENKENKENKENKENKENKENKENKENKENKENKENKENKENNVALSSSLHLQFNLEAVVQPSLFHEDDIHGVVP
SELNPGVAKLIGQAIGSAMQAKGLSDIVIGRDGRVSSSELSAALSDGLRHAGCNVVDIGLVPIPVVYFAACHLGVWSCVA
VTGGHHPHDYNGFKIVLGGESLSSEAMSDLYQCITNGRLYASVDSGSLSERDVVDDYIQRIADDVQLNRPLKIVVDPGHG
AAEEILSRLFKAIGADLVSLYGDIDGVSLIVHPDSGEPGNLQKLIQRVERADADLGLAFDGDAESLRVVTREGEVILSDS
VLMLFATDVLQRNPGALVIYDAECTSKLSDYVLRNGGSPLMWKIGHSSIKAKMRETGAELAGEMSGYFFFKERWYGFEDA
LYAAARLLEILAQREDNPSQVFAALPHAYFTAQMEQSVEGDAQACVQSFIEEVQRSVEGGVFDGARLFAFDGLRADFTDG
WGLVRVSDTASALVLRFEADTQAGLERIQSAFRTHLQALLPGQVLVF

Sequences:

>Translated_847_residues
MSVTIGNELILPMKRRRIAFLLAMLCLLLAGVFCWGAYIQWRQNVVQQKLEQARDGAVASLLQVLSAQVKQLQNVVQRPA
IVQVLGGGDVTAAAAAVREQFPGTEDVQVLTGDLSAAYADVARSGYARLGLIEAALGGDGVKAWVVRDGTQIGLGMAVMV
KLGQAPAVVYLRLPLRGLISVLDAIEVPNSTYLALRQGSYTVVERGSAALASGGEALAKPLGWADLRMAAAVPQLENVPF
DLGLLPSLIVVGVFALVAAVLLLVAGGHRMLPRRHGQMADAEQEQVTLRESVMQEAPERAIVLNDENKENKENKENKENK
ENKENKENKENKENKENKENKENKENKENKENKENKENKENKENKENNVALSSSLHLQFNLEAVVQPSLFHEDDIHGVVP
SELNPGVAKLIGQAIGSAMQAKGLSDIVIGRDGRVSSSELSAALSDGLRHAGCNVVDIGLVPIPVVYFAACHLGVWSCVA
VTGGHHPHDYNGFKIVLGGESLSSEAMSDLYQCITNGRLYASVDSGSLSERDVVDDYIQRIADDVQLNRPLKIVVDPGHG
AAEEILSRLFKAIGADLVSLYGDIDGVSLIVHPDSGEPGNLQKLIQRVERADADLGLAFDGDAESLRVVTREGEVILSDS
VLMLFATDVLQRNPGALVIYDAECTSKLSDYVLRNGGSPLMWKIGHSSIKAKMRETGAELAGEMSGYFFFKERWYGFEDA
LYAAARLLEILAQREDNPSQVFAALPHAYFTAQMEQSVEGDAQACVQSFIEEVQRSVEGGVFDGARLFAFDGLRADFTDG
WGLVRVSDTASALVLRFEADTQAGLERIQSAFRTHLQALLPGQVLVF
>Mature_846_residues
SVTIGNELILPMKRRRIAFLLAMLCLLLAGVFCWGAYIQWRQNVVQQKLEQARDGAVASLLQVLSAQVKQLQNVVQRPAI
VQVLGGGDVTAAAAAVREQFPGTEDVQVLTGDLSAAYADVARSGYARLGLIEAALGGDGVKAWVVRDGTQIGLGMAVMVK
LGQAPAVVYLRLPLRGLISVLDAIEVPNSTYLALRQGSYTVVERGSAALASGGEALAKPLGWADLRMAAAVPQLENVPFD
LGLLPSLIVVGVFALVAAVLLLVAGGHRMLPRRHGQMADAEQEQVTLRESVMQEAPERAIVLNDENKENKENKENKENKE
NKENKENKENKENKENKENKENKENKENKENKENKENKENKENKENNVALSSSLHLQFNLEAVVQPSLFHEDDIHGVVPS
ELNPGVAKLIGQAIGSAMQAKGLSDIVIGRDGRVSSSELSAALSDGLRHAGCNVVDIGLVPIPVVYFAACHLGVWSCVAV
TGGHHPHDYNGFKIVLGGESLSSEAMSDLYQCITNGRLYASVDSGSLSERDVVDDYIQRIADDVQLNRPLKIVVDPGHGA
AEEILSRLFKAIGADLVSLYGDIDGVSLIVHPDSGEPGNLQKLIQRVERADADLGLAFDGDAESLRVVTREGEVILSDSV
LMLFATDVLQRNPGALVIYDAECTSKLSDYVLRNGGSPLMWKIGHSSIKAKMRETGAELAGEMSGYFFFKERWYGFEDAL
YAAARLLEILAQREDNPSQVFAALPHAYFTAQMEQSVEGDAQACVQSFIEEVQRSVEGGVFDGARLFAFDGLRADFTDGW
GLVRVSDTASALVLRFEADTQAGLERIQSAFRTHLQALLPGQVLVF

Specific function: The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to it

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=339, Percent_Identity=33.3333333333333, Blast_Score=169, Evalue=9e-43,
Organism=Escherichia coli, GI1789566, Length=361, Percent_Identity=26.0387811634349, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2; =5.4.2.8 [H]

Molecular weight: Translated: 91799; Mature: 91667

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTIGNELILPMKRRRIAFLLAMLCLLLAGVFCWGAYIQWRQNVVQQKLEQARDGAVAS
CEEECCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LLQVLSAQVKQLQNVVQRPAIVQVLGGGDVTAAAAAVREQFPGTEDVQVLTGDLSAAYAD
HHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECHHHHHHHH
VARSGYARLGLIEAALGGDGVKAWVVRDGTQIGLGMAVMVKLGQAPAVVYLRLPLRGLIS
HHHCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHH
VLDAIEVPNSTYLALRQGSYTVVERGSAALASGGEALAKPLGWADLRMAAAVPQLENVPF
HHHHHCCCCCCEEEEECCCEEEEECCCHHHHCCCHHHHCCCCHHHHHHHHHCCHHHCCCC
DLGLLPSLIVVGVFALVAAVLLLVAGGHRMLPRRHGQMADAEQEQVTLRESVMQEAPERA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCE
IVLNDENKENKENKENKENKENKENKENKENKENKENKENKENKENKENKENKENKENKE
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKENKENNVALSSSLHLQFNLEAVVQPSLFHEDDIHGVVPSELNPGVAKLIGQAIGSAMQ
HCCCCCCCEEEEEEEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AKGLSDIVIGRDGRVSSSELSAALSDGLRHAGCNVVDIGLVPIPVVYFAACHLGVWSCVA
HCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHH
VTGGHHPHDYNGFKIVLGGESLSSEAMSDLYQCITNGRLYASVDSGSLSERDVVDDYIQR
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
IADDVQLNRPLKIVVDPGHGAAEEILSRLFKAIGADLVSLYGDIDGVSLIVHPDSGEPGN
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
LQKLIQRVERADADLGLAFDGDAESLRVVTREGEVILSDSVLMLFATDVLQRNPGALVIY
HHHHHHHHHHCCCCCCEEECCCCCCEEEEEECCCEEEECCHHHHHHHHHHHCCCCEEEEE
DAECTSKLSDYVLRNGGSPLMWKIGHSSIKAKMRETGAELAGEMSGYFFFKERWYGFEDA
CCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEHHHCCCHHHH
LYAAARLLEILAQREDNPSQVFAALPHAYFTAQMEQSVEGDAQACVQSFIEEVQRSVEGG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
VFDGARLFAFDGLRADFTDGWGLVRVSDTASALVLRFEADTQAGLERIQSAFRTHLQALL
CCCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHC
PGQVLVF
CCCEEEC
>Mature Secondary Structure 
SVTIGNELILPMKRRRIAFLLAMLCLLLAGVFCWGAYIQWRQNVVQQKLEQARDGAVAS
EEECCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LLQVLSAQVKQLQNVVQRPAIVQVLGGGDVTAAAAAVREQFPGTEDVQVLTGDLSAAYAD
HHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECHHHHHHHH
VARSGYARLGLIEAALGGDGVKAWVVRDGTQIGLGMAVMVKLGQAPAVVYLRLPLRGLIS
HHHCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHH
VLDAIEVPNSTYLALRQGSYTVVERGSAALASGGEALAKPLGWADLRMAAAVPQLENVPF
HHHHHCCCCCCEEEEECCCEEEEECCCHHHHCCCHHHHCCCCHHHHHHHHHCCHHHCCCC
DLGLLPSLIVVGVFALVAAVLLLVAGGHRMLPRRHGQMADAEQEQVTLRESVMQEAPERA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCE
IVLNDENKENKENKENKENKENKENKENKENKENKENKENKENKENKENKENKENKENKE
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKENKENNVALSSSLHLQFNLEAVVQPSLFHEDDIHGVVPSELNPGVAKLIGQAIGSAMQ
HCCCCCCCEEEEEEEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AKGLSDIVIGRDGRVSSSELSAALSDGLRHAGCNVVDIGLVPIPVVYFAACHLGVWSCVA
HCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHH
VTGGHHPHDYNGFKIVLGGESLSSEAMSDLYQCITNGRLYASVDSGSLSERDVVDDYIQR
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
IADDVQLNRPLKIVVDPGHGAAEEILSRLFKAIGADLVSLYGDIDGVSLIVHPDSGEPGN
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
LQKLIQRVERADADLGLAFDGDAESLRVVTREGEVILSDSVLMLFATDVLQRNPGALVIY
HHHHHHHHHHCCCCCCEEECCCCCCEEEEEECCCEEEECCHHHHHHHHHHHCCCCEEEEE
DAECTSKLSDYVLRNGGSPLMWKIGHSSIKAKMRETGAELAGEMSGYFFFKERWYGFEDA
CCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEHHHCCCHHHH
LYAAARLLEILAQREDNPSQVFAALPHAYFTAQMEQSVEGDAQACVQSFIEEVQRSVEGG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
VFDGARLFAFDGLRADFTDGWGLVRVSDTASALVLRFEADTQAGLERIQSAFRTHLQALL
CCCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHC
PGQVLVF
CCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]