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The map label for this gene is hflX [H]

Identifier: 182680628

GI number: 182680628

Start: 86569

End: 87921

Strand: Reverse

Name: hflX [H]

Synonym: XfasM23_0057

Alternate gene names: 182680628

Gene position: 87921-86569 (Counterclockwise)

Preceding gene: 182680629

Following gene: 182680627

Centisome position: 3.47

GC content: 53.81

Gene sequence:

>1353_bases
GTGTTTGACCGCTCACGCAAAGGCGAGTATGCGTTGCTGATCCAGCCCCTCACCGATCACTCTGCCGAAGACGGCGCTTT
GGAGGAATTTGCGGACCTGACCAGGTCCGCAGGGGCAACTGTTGCTGGATCTCTCGCCGTTCGGATACATCGTCCGAACC
CATCAACACTGCTTAGCAGCGGTAAGTTAAAAGAAATAAAGGAAACCGCCGACGCAACCGGGGCGGACCTGATACTGATT
AATCATTCACTCTCCCCCGTGCAAGAACGTAATCTGGAAAAGTCTCTTGAACGTCGCGTGATTGATCGTACGGGGCTTAT
TCTGGACATCTTCGCACAACGCGCATGCAGCCACGAAGGCAAGCTGCAAGTCGAGTTAGCACAGCTACGGCACTTGGCAA
CACGGTTGGTACGCGGATGGACTCACCTAGAACGCCAACGTGGTGGTGCGATCGGTCTGCGTGGCCCCGGTGAAACTCAG
TTGGAAACTGATCGCCGCTTATTGCAAAAACGGGTGGAACAACTACAGAAACGCCTCAGTAAAGTCGAGGTGCAGCGCAC
CCAGATGCGTCGCGCAAGAGTGCGTAGCGAAGTGCCACGTATCGCACTCGTTGGCTATACCAACTCCGGTAAATCGACTT
TGTTTAATGCACTCACCGGTGCTTCTGCTTACACAGCCAACCAACTGTTCGCCACGCTAGACCCCAAAGTACGCCGTATT
GTCCTGCCCGGCAGCAGTGCGATGCTTGCCGACACTGTAGGCTTTGTGCGTCATTTACCGCACGAACTGGTAGCCGCATT
CCGCTCTACGCTGTCGGAAGCACGCGAAGCTGATCTGCTACTACATGTCATTGACGCAGCCGATCCACTACGTGAGGAAC
GCATCGACCAAGTCGACGAAGTACTACAAGCAATCGGTGCCGGTGAACTGCCGCAATTACTGGTGTTCAACAAAATCGAT
TGCATTGAGGGCGCAGAAGTGCGCCAGGACGCGCAGGACGGGATACCTGACCAAGCACGACGCGAGCGTGTGTGGTTGTC
CGCACGTCATGGACACGGCGTTGAGTTGCTGCAACAAATACTGAATCATCGCTTGAAGATCCAGAATGTACAGAGCGAAC
TACGCTTGCCGCCTTCAGAAGGACGTTTACGCGCACGTCTTCACGAACTCAAGGGAGTACGCGAAGAGCAGACTGATGAG
CATGGTTGGTTGCTAAAAATCGATCTTTCTTTAGCTGAAATTGAACGCTTAGCCGCAAGCGACTATGGAATACCGCTGCG
TGCATTGCTGCAAGATCACCGTGATGCTTGGACTCCAACTCTGCACTCAAAGTATGTATCCGCCGAATACTAG

Upstream 100 bases:

>100_bases
CACGCAACGTACGAGTTGGCCCAGGTGGAGGCTATGTGCATTCAGGTAGTGATACGTTGCAAATTAATGATGACGAAGTG
GAATGATCCGGGAGTGAGGT

Downstream 100 bases:

>100_bases
GTGCTACCAAACTTAAAACTTTTGACAGCATTACGGAGCGCCCTTTTGATGTCCGACAGCCTCTCCACTGCACTTTCACA
CTACACAGCAGAGGAGAAGC

Product: GTP-binding proten HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MFDRSRKGEYALLIQPLTDHSAEDGALEEFADLTRSAGATVAGSLAVRIHRPNPSTLLSSGKLKEIKETADATGADLILI
NHSLSPVQERNLEKSLERRVIDRTGLILDIFAQRACSHEGKLQVELAQLRHLATRLVRGWTHLERQRGGAIGLRGPGETQ
LETDRRLLQKRVEQLQKRLSKVEVQRTQMRRARVRSEVPRIALVGYTNSGKSTLFNALTGASAYTANQLFATLDPKVRRI
VLPGSSAMLADTVGFVRHLPHELVAAFRSTLSEAREADLLLHVIDAADPLREERIDQVDEVLQAIGAGELPQLLVFNKID
CIEGAEVRQDAQDGIPDQARRERVWLSARHGHGVELLQQILNHRLKIQNVQSELRLPPSEGRLRARLHELKGVREEQTDE
HGWLLKIDLSLAEIERLAASDYGIPLRALLQDHRDAWTPTLHSKYVSAEY

Sequences:

>Translated_450_residues
MFDRSRKGEYALLIQPLTDHSAEDGALEEFADLTRSAGATVAGSLAVRIHRPNPSTLLSSGKLKEIKETADATGADLILI
NHSLSPVQERNLEKSLERRVIDRTGLILDIFAQRACSHEGKLQVELAQLRHLATRLVRGWTHLERQRGGAIGLRGPGETQ
LETDRRLLQKRVEQLQKRLSKVEVQRTQMRRARVRSEVPRIALVGYTNSGKSTLFNALTGASAYTANQLFATLDPKVRRI
VLPGSSAMLADTVGFVRHLPHELVAAFRSTLSEAREADLLLHVIDAADPLREERIDQVDEVLQAIGAGELPQLLVFNKID
CIEGAEVRQDAQDGIPDQARRERVWLSARHGHGVELLQQILNHRLKIQNVQSELRLPPSEGRLRARLHELKGVREEQTDE
HGWLLKIDLSLAEIERLAASDYGIPLRALLQDHRDAWTPTLHSKYVSAEY
>Mature_450_residues
MFDRSRKGEYALLIQPLTDHSAEDGALEEFADLTRSAGATVAGSLAVRIHRPNPSTLLSSGKLKEIKETADATGADLILI
NHSLSPVQERNLEKSLERRVIDRTGLILDIFAQRACSHEGKLQVELAQLRHLATRLVRGWTHLERQRGGAIGLRGPGETQ
LETDRRLLQKRVEQLQKRLSKVEVQRTQMRRARVRSEVPRIALVGYTNSGKSTLFNALTGASAYTANQLFATLDPKVRRI
VLPGSSAMLADTVGFVRHLPHELVAAFRSTLSEAREADLLLHVIDAADPLREERIDQVDEVLQAIGAGELPQLLVFNKID
CIEGAEVRQDAQDGIPDQARRERVWLSARHGHGVELLQQILNHRLKIQNVQSELRLPPSEGRLRARLHELKGVREEQTDE
HGWLLKIDLSLAEIERLAASDYGIPLRALLQDHRDAWTPTLHSKYVSAEY

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=216, Percent_Identity=36.5740740740741, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310124267, Length=216, Percent_Identity=36.5740740740741, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310124171, Length=216, Percent_Identity=36.5740740740741, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310124169, Length=216, Percent_Identity=36.5740740740741, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310133118, Length=238, Percent_Identity=34.8739495798319, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI310133116, Length=235, Percent_Identity=35.7446808510638, Blast_Score=112, Evalue=7e-25,
Organism=Escherichia coli, GI1790615, Length=423, Percent_Identity=54.6099290780142, Blast_Score=427, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17561038, Length=371, Percent_Identity=28.8409703504043, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24650079, Length=383, Percent_Identity=32.6370757180157, Blast_Score=118, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50423; Mature: 50423

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRSRKGEYALLIQPLTDHSAEDGALEEFADLTRSAGATVAGSLAVRIHRPNPSTLLSS
CCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEECEEEEEEECCCCHHHHCC
GKLKEIKETADATGADLILINHSLSPVQERNLEKSLERRVIDRTGLILDIFAQRACSHEG
CCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
KLQVELAQLRHLATRLVRGWTHLERQRGGAIGLRGPGETQLETDRRLLQKRVEQLQKRLS
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KVEVQRTQMRRARVRSEVPRIALVGYTNSGKSTLFNALTGASAYTANQLFATLDPKVRRI
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEE
VLPGSSAMLADTVGFVRHLPHELVAAFRSTLSEAREADLLLHVIDAADPLREERIDQVDE
EECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VLQAIGAGELPQLLVFNKIDCIEGAEVRQDAQDGIPDQARRERVWLSARHGHGVELLQQI
HHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHEEECCCCCCHHHHHHH
LNHRLKIQNVQSELRLPPSEGRLRARLHELKGVREEQTDEHGWLLKIDLSLAEIERLAAS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHCCCCCCCEEEEECCHHHHHHHHHC
DYGIPLRALLQDHRDAWTPTLHSKYVSAEY
CCCCCHHHHHHHHHHCCCCCHHHHHCCCCC
>Mature Secondary Structure
MFDRSRKGEYALLIQPLTDHSAEDGALEEFADLTRSAGATVAGSLAVRIHRPNPSTLLSS
CCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEECEEEEEEECCCCHHHHCC
GKLKEIKETADATGADLILINHSLSPVQERNLEKSLERRVIDRTGLILDIFAQRACSHEG
CCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
KLQVELAQLRHLATRLVRGWTHLERQRGGAIGLRGPGETQLETDRRLLQKRVEQLQKRLS
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KVEVQRTQMRRARVRSEVPRIALVGYTNSGKSTLFNALTGASAYTANQLFATLDPKVRRI
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEE
VLPGSSAMLADTVGFVRHLPHELVAAFRSTLSEAREADLLLHVIDAADPLREERIDQVDE
EECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VLQAIGAGELPQLLVFNKIDCIEGAEVRQDAQDGIPDQARRERVWLSARHGHGVELLQQI
HHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHEEECCCCCCHHHHHHH
LNHRLKIQNVQSELRLPPSEGRLRARLHELKGVREEQTDEHGWLLKIDLSLAEIERLAAS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHCCCCCCCEEEEECCHHHHHHHHHC
DYGIPLRALLQDHRDAWTPTLHSKYVSAEY
CCCCCHHHHHHHHHHCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]