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The map label for this gene is ctpA [H]

Identifier: 170757682

GI number: 170757682

Start: 3700976

End: 3702181

Strand: Reverse

Name: ctpA [H]

Synonym: CLD_1119

Alternate gene names: 170757682

Gene position: 3702181-3700976 (Counterclockwise)

Preceding gene: 170754710

Following gene: 170756601

Centisome position: 93.53

GC content: 28.44

Gene sequence:

>1206_bases
TTGAAAAAAAATAAAAAATGGATTATATGGACAGTAGTTATAGTATTAGTAACAAATATTTTTACATTTTTAGGTACAAA
TTTGGTTTCTTTATATTTGCCTAATGGCAAAGTTATAATTGGAGCAGACCAATATAAAGATATATTGAAATATCAAAAGA
TGTTTTTAATAAGAAATCAAATATATAAGTATTACGATGGTAAAATAGATGAAAGTAAGATGGTAGAAGGTGCAGTAAAA
GGAATGACAGAATCTTTAAATGACCCTTATACTGTATTTATGAATGCTAAAGAGTACAAAGAATTTAATGCTCAAACAGA
AGGTAATTATAGTGGCGTAGGAATACAAATACAAGCTAAAGATGATAAAATAATTGTAGCTTCTACTTTTGAAGGATCTC
CGGCTAAAGAGGCAGGAATACTACCAAAGGATGAAATTCAAAAAGTTAATAATACAACGGTATCAGGAAAAGAGTTGGAA
AAGGCTGTTTCCATAATGAAGGGAAAAGAAGGCACAGATGTTAAATTACAATTATATAGAAAAGAAAAAGGAAGTTTTGA
AGTAACACTAAAGAGAAAAAAGATAGATATACCTACTATAAAATCAGAAATGATTGATAATAATATAGGATATATACAAG
TAAGTATGTTTGATGAAAATACTTCAAAGAACTTTAAGAATGCTTTAAATGATTTAAAAGATAAGGGTATGAAATCTTTA
TTATTAGATTTGAGAGGAAATCCAGGAGGGCTATTAGATGAATGTATTAATATGGCTTCTAATTTTATAGAAAAGGGAAA
GGTTGTAGTATCGACTATAGATAAATATGGAAGCAAAAAAGAATATAAATCTAAAGGTGGAGATTTTATAGGATTTCCAG
TAACTATATTAGTAGATGAAGGTTCTGCAAGTGCTTCAGAGGTATTTTTAGGAGCCATGAAAGACTATAATGCAGCCACA
TCTATAGGAAAGAAAACTTTTGGAAAGGGTGTAGTTCAAACTATAATAGAGACTGGTGATAATACGGCCCTTAAAGTTAC
GATTTCAAAATATTATTCACCTAAAGGTGTAAACATAAATCATAAAGGAATAACTCCAGATATGGAAATAGATTATCCAG
AGGAGTTAAGAAAGAAAGAATATGATAGGAAAGTAGATCCTCAATTTAATAAAGCTTTAAATATTGCAAAATCAAAGATA
AGATAA

Upstream 100 bases:

>100_bases
TTTAAAATTAATTTTTTATTTTCTGTAATAATGTATTATTTAATATATAATACTTATATATTACTAATATATATTAAGGC
TAAACAAAGAGGTGGGTAAT

Downstream 100 bases:

>100_bases
TATTGTATTTGATCTTTATATTTTTATATAGATGGTTTAGTTAGACTTTCTAACTAAACCATAGTTATGGAGAGGGGAAT
TTTTTTTAATGGACATATTA

Product: carboxyl-terminal protease

Products: NA

Alternate protein names: C-terminal processing protease [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKKNKKWIIWTVVIVLVTNIFTFLGTNLVSLYLPNGKVIIGADQYKDILKYQKMFLIRNQIYKYYDGKIDESKMVEGAVK
GMTESLNDPYTVFMNAKEYKEFNAQTEGNYSGVGIQIQAKDDKIIVASTFEGSPAKEAGILPKDEIQKVNNTTVSGKELE
KAVSIMKGKEGTDVKLQLYRKEKGSFEVTLKRKKIDIPTIKSEMIDNNIGYIQVSMFDENTSKNFKNALNDLKDKGMKSL
LLDLRGNPGGLLDECINMASNFIEKGKVVVSTIDKYGSKKEYKSKGGDFIGFPVTILVDEGSASASEVFLGAMKDYNAAT
SIGKKTFGKGVVQTIIETGDNTALKVTISKYYSPKGVNINHKGITPDMEIDYPEELRKKEYDRKVDPQFNKALNIAKSKI
R

Sequences:

>Translated_401_residues
MKKNKKWIIWTVVIVLVTNIFTFLGTNLVSLYLPNGKVIIGADQYKDILKYQKMFLIRNQIYKYYDGKIDESKMVEGAVK
GMTESLNDPYTVFMNAKEYKEFNAQTEGNYSGVGIQIQAKDDKIIVASTFEGSPAKEAGILPKDEIQKVNNTTVSGKELE
KAVSIMKGKEGTDVKLQLYRKEKGSFEVTLKRKKIDIPTIKSEMIDNNIGYIQVSMFDENTSKNFKNALNDLKDKGMKSL
LLDLRGNPGGLLDECINMASNFIEKGKVVVSTIDKYGSKKEYKSKGGDFIGFPVTILVDEGSASASEVFLGAMKDYNAAT
SIGKKTFGKGVVQTIIETGDNTALKVTISKYYSPKGVNINHKGITPDMEIDYPEELRKKEYDRKVDPQFNKALNIAKSKI
R
>Mature_401_residues
MKKNKKWIIWTVVIVLVTNIFTFLGTNLVSLYLPNGKVIIGADQYKDILKYQKMFLIRNQIYKYYDGKIDESKMVEGAVK
GMTESLNDPYTVFMNAKEYKEFNAQTEGNYSGVGIQIQAKDDKIIVASTFEGSPAKEAGILPKDEIQKVNNTTVSGKELE
KAVSIMKGKEGTDVKLQLYRKEKGSFEVTLKRKKIDIPTIKSEMIDNNIGYIQVSMFDENTSKNFKNALNDLKDKGMKSL
LLDLRGNPGGLLDECINMASNFIEKGKVVVSTIDKYGSKKEYKSKGGDFIGFPVTILVDEGSASASEVFLGAMKDYNAAT
SIGKKTFGKGVVQTIIETGDNTALKVTISKYYSPKGVNINHKGITPDMEIDYPEELRKKEYDRKVDPQFNKALNIAKSKI
R

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Associated With The Periplasmic Protein Side Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=306, Percent_Identity=30.3921568627451, Blast_Score=131, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 44853; Mature: 44853

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNKKWIIWTVVIVLVTNIFTFLGTNLVSLYLPNGKVIIGADQYKDILKYQKMFLIRNQ
CCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHH
IYKYYDGKIDESKMVEGAVKGMTESLNDPYTVFMNAKEYKEFNAQTEGNYSGVGIQIQAK
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCCCCCEEEEEEEC
DDKIIVASTFEGSPAKEAGILPKDEIQKVNNTTVSGKELEKAVSIMKGKEGTDVKLQLYR
CCEEEEEEECCCCCCHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEE
KEKGSFEVTLKRKKIDIPTIKSEMIDNNIGYIQVSMFDENTSKNFKNALNDLKDKGMKSL
CCCCCEEEEEEEEECCCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LLDLRGNPGGLLDECINMASNFIEKGKVVVSTIDKYGSKKEYKSKGGDFIGFPVTILVDE
HHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCHHHHHCCCCEEECEEEEEEEC
GSASASEVFLGAMKDYNAATSIGKKTFGKGVVQTIIETGDNTALKVTISKYYSPKGVNIN
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
HKGITPDMEIDYPEELRKKEYDRKVDPQFNKALNIAKSKIR
CCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKNKKWIIWTVVIVLVTNIFTFLGTNLVSLYLPNGKVIIGADQYKDILKYQKMFLIRNQ
CCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHH
IYKYYDGKIDESKMVEGAVKGMTESLNDPYTVFMNAKEYKEFNAQTEGNYSGVGIQIQAK
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCCCCCEEEEEEEC
DDKIIVASTFEGSPAKEAGILPKDEIQKVNNTTVSGKELEKAVSIMKGKEGTDVKLQLYR
CCEEEEEEECCCCCCHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEE
KEKGSFEVTLKRKKIDIPTIKSEMIDNNIGYIQVSMFDENTSKNFKNALNDLKDKGMKSL
CCCCCEEEEEEEEECCCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LLDLRGNPGGLLDECINMASNFIEKGKVVVSTIDKYGSKKEYKSKGGDFIGFPVTILVDE
HHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCHHHHHCCCCEEECEEEEEEEC
GSASASEVFLGAMKDYNAATSIGKKTFGKGVVQTIIETGDNTALKVTISKYYSPKGVNIN
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
HKGITPDMEIDYPEELRKKEYDRKVDPQFNKALNIAKSKIR
CCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8996100; 9734814; 9384377 [H]