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The map label for this gene is lgrC [H]

Identifier: 170751897

GI number: 170751897

Start: 5843257

End: 5847327

Strand: Direct

Name: lgrC [H]

Synonym: Mrad2831_5529

Alternate gene names: 170751897

Gene position: 5843257-5847327 (Clockwise)

Preceding gene: 170751896

Following gene: 170751898

Centisome position: 96.14

GC content: 72.19

Gene sequence:

>4071_bases
ATGAGCGACGTCGCCGAGAAGACCCGGCCCGGCCCGGCGGCCGGGGAGCCCGCGCCTCTCGGGAACGCGGCGGCGATCCT
GCGCGGCGACCACCGGCCCGACCTGATCCGCGACGAAGTTCTGGCCGAGATCTTCCTGCACTCGGCCGCGACCCGGCCCG
GCCATCCCTGCCTCGTCGACGGCGCCCGGGTCGAGGCTGGGGGCGTCCACCCGCACCTGACCTACGCGGACGTCGCCGCC
CGGGCCGGCCGGATCGCCGCCGGCCTCGCCCATCGCGGCATCGGTCCCGGCGACGTCGTCGGCCTGTGGATGGCCCGCGG
CCCGGACCTCCTCGTCGCGCAGATCGGGATCACGATGTCGGGGGCGGCGTGGCTGCCCTTCGATGCCGAGGCGCCGGCCG
ACCGGGTGGGCGTTTGCCTCACCGACGCGGGCGCGAAGGCGCTGCTCGTCTCCCCGGCGCTCGCCGCCGCGGCGCCGGAC
GCCGCGCCCGCGTTGACGCCCGCCGACCTCGACGCCGGAACGCCCGCCGACGCGCCGGTGCCGGACCCGCGCGCGGCCGG
GCTGACGCCCGAGCACCCCGCCTACCTGATCTACACCTCCGGCTCGACCGGCGTGCCCAAGGGCATCGTCATCAGCCACG
CCAACATCTGCCACTTCCTGAGGTCGGGGAACGCCCTCTACGGGATGCGCGCGGACGACGTGGTCTTCCAGGGCGCCTCG
GTGGCGTTCGACCTCTCGATGGAGGAGATCTGGGTCCCGTACCTCGTGGGCGCGACCCTGTTCGTCGCGAGCCCCGCCAT
GATGGGCGACCTGGAGTCGCTCCCCGGCATCCTGGAGGCCGAGGGCATCACGGTGCTCGACACCGTCCCGACGCTGCTGG
CGATGATCTCCGGCGACCTGCCGCGGGTCCGCCTCGTCCTGCTCGGCGGCGAGGCGCTGCCCGAGCCGCTGATCGCCCGC
TGGGCGACGGGCGGGCGCCAGCTGTTCAACACCTACGGGCCCACGGAGGCAACCGTGGTGGCGACCGCGGCCGAGATGCG
CCCCGGCGAGCCGGTGACGATCGGCGGCCCGATCCCGAACTACTCCGTCTACGTCGCCGGCGAGGACCTTTCCCTGCTCG
GCCGCGACCAGCAGGGCGAGCTGCTGATCGGCGGTCCCGGCGTCGCGCGGGGCTACCTCGCCCGTCCCGAGCTGACGGCG
GAGAAGTTCATCGCCAACCCCTTCGCGTCGGACGGGACCGACCCCGTCCTGTACCGTTCGGGCGACGCGGTCTCCCTCGA
TGCCGCGGGCCGGATCGTGTTCCACGGCCGGATCGACGACCAGGTGAAGATCCGCGGCTTCCGCGTGGAGCTGGGCGAGA
TCGAGTCCCGGATCCGCGCGGTGCCCGACATCAACCAGGCCGCCGTCGTGCTCCGGCAGGACGACGGCGTCGACCGCCTC
GTGGCCTTCCTGATCCCGGAGCGGGGCCGGTCCATCGACGCCGCCGCCCTGCGCCGGACGCTCGCCGGGCAGATGCCGCC
CTACATGGTGCCCGGCCATTTCGAGGTGGCCGAGACGCTCCCGCGCCTGACCTCCGGCAAGGTCGACCGCAAGGCGCTGA
AGATCGCCCCGCTCACCGTGGTCGCCGCGGACGGCGAGCAGGAGCCGCCCGCCAACGAGACCGAGGCGGCCCTCGTCGCG
GCCGCCAAGCAGATCTTCGGCAACCAGCCGATCGCTCTCGAGGGCGACTTCTTCTCCGATCTCGGCGGCCACTCGCTCCT
GGCCGCCCGCTTCGTCTCGGCGGTGCGCGAGAACCCGCCGCTCGCCGGCATCACCCTGCCCGACGTCTACGCCCTGCGCA
CCGTGCGGGCGATGGCCGACGCGCTCATCGCCCGCACGGGCGGGATGGGGGCCGGGGCCGCGACGCGCGACCTGAGTTTC
GAGCCGCCGCCGCTGCTGCGCCGGGCGCTCTGCGGCCTCGCGCAGCTCGTCGCGCTGCCCTTCGTGATCGCGCTGGCCAC
CGCGCAGTGGCTCGGCATGTTCGTGACCTACCTGCTGCTCACCGGCGGGGGATTGAGCTTCTTCGCCGAGCTCGGGGTGC
TGCTCCTCGTCTACGTGGCGATCAACGGCGTGACCGCCGTGGCGGCAGTCGCCGGCAAGTGGCTGATCCTCGGCCGGACC
AGGCCGGGCCGTTACCCGCTCTGGGGCACCTACTACTACCGCTGGTGGCTCGCGCAGCGGCTGGCGCCCCTCGTCCACGT
GAAGTGGCTGCAGGGCTCGCCGGCCATCGCGATCTACCTGCGGCTCATGGGCGCCAAGGTCGGCCGCGACACCCTGATCT
CCGACATCGAGATCGGCGCGCCCGACCTCCTGACCATCGGCGACGGCGCGTCCCTGGGCGGCCGCCTCGTCATCGCCAAC
GCCGAGATCGTCGGCAACGAGCTGGTCATCGGCACGGCCGAGATCGGCGCGGACGCGGCGGTCGGGACCTCCTGCGTGAT
CAGCCACGACACGGTGATCGGCCCGCAGGCGGAGATCGCCGACCTGACCACGATCCCGGCGGGCTCGCGGGTCGGCGCGG
CCGAGCGCTGGGACGGCTCGCCCGGCCGCAAGGTCGGCATGGCCGAGCCGTCGGACCTCCCCGCGCCCGCCGAGGCGTCT
TTCGCGCGCCGCGCGGCCTTCCTGGCGGCCTACGTCGTGCTGCTCGGCGCCATCCCGGCGGTCGGCCTGCTGCCGATCTT
CCCGGCCTTCTTCATCTTCGACCAGATCTCGGACTCGCTCTCCGACATCACCGACGTCGACTACCACTGGTACCTGCCGA
TCCTCACGTGGCCCACCGCCATGCTGATGACCGCCGGCACGGTGCTGCTGATCGCCGGCATCCGCTGGATCGTGCTGCCG
CGGACGCGGTCCGGCACCTACTCGGTCCACTCGCTGTTCTACCTGCGGAAATGGTCGCTGGCCCTCGCGGTCGAGGTGAC
GCTGGAGACGCTCTCGTCGCTGTTCGCGACCGTCTACATGCGGGCGTGGTACCGGCTGATGGGCGCCAATATGGGCCACG
GTGCCGAGATCTCGACCAACCTCGCGGGCCGCTACGACCTCGCCGAGGTCGGCGCGAAGAACTTCGTCGCCGACGAGGTG
GTGTACGGCGAGGAGGAGATCCGGCGCGGCTGGATGCACCTGGAGCCGACCCGCACCGGGGCGCGGGTCTTCGTCGGCAA
CGACGCGGTGGTGCCGCCGGGCGCCGTCATCCCCGACGACGTGCTCATCGGGATCAAGTCAAAGCCGCCCGAGAACGCCG
CGATGAGCCCGGGCGAGACGTGGTTCGGCTCGCCGCCGATCCGGCTGCCCGCCCGCCAGAAGGTCGATCTCGGCTCGACC
GCCCAGACCTACGAGCCCGGCGCGTGGCCGAAGATCCGGCGCGGCGTCTTCGAGGCCTTCGCGACCTCGTTCTCGCCGAT
GCTCTACATCACCCTCGCGATCACGGCGATCGACTGGTACTTCTACCCGGCCATCCTGGAGCAGGACTGGTGGGGCCTGG
CCTACAGCTTCGTCGGGGCGAGCGTCGCCATCGCGCTGATCCAGTCCTCGGCGGTCATCGCCATGAAGTGGCTGCTGATG
GGCGTCTACAAGCCCGGCATGCAGCCGATGTGGTCGTGGTGGGCGATGCGCACCGAGGCGATCGCGGTGGCCTACTGGGG
CCTCGCCGGCAAGGTGCTGCTCGAACACCTCCAGGGCACGCCCTTCCTCCCCTGGGTGCTGCGGCTGTTCGGCGTGAAGG
TCGGCAAGGGCGTGTGCATGCTCACGACCGACATCACCGAGTTCGACTGCGTCACCATCGGCGACTACGCCACGATCAAC
CGCGTCTCCGCGCTGCAGACCCACCTCTACGAGGACCGGATCATGAAGATCGGCCGCGTCGTCGTCGGGCGCGGCGTCTC
GGTCGGCGCGTTCTCGACCGTGCTGTACGACACGAAGGTCGGGGATTACGCCCGCCTGCGGCCGCTCACCATCGTCATGA
AGGGCGAGTCGATCCCCGCCAACACCGAGTGGGAGGGCGCGCCCGCGGTCCCGGTGGTCCACCGCGCCTGA

Upstream 100 bases:

>100_bases
GGCGCAGTGCAAAGCCGCCTCGATAACGGCATGATCGGCAGGCTATAGGGCGGCGGCCAGGACAGGCGCCGGCTCGAGCG
GCCGGCCAGCGGAGCAGCGG

Downstream 100 bases:

>100_bases
CCGACGGAACACGTCTAAGGTTCCGGCTCGCTGGCGGCGTGTCGGAGCGCCGCGGCTCGATCTGCGGGAGACGCCGGCAC
GGTGATGGCCTGTCCGACCC

Product: non-ribosomal peptide synthetase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1356; Mature: 1355

Protein sequence:

>1356_residues
MSDVAEKTRPGPAAGEPAPLGNAAAILRGDHRPDLIRDEVLAEIFLHSAATRPGHPCLVDGARVEAGGVHPHLTYADVAA
RAGRIAAGLAHRGIGPGDVVGLWMARGPDLLVAQIGITMSGAAWLPFDAEAPADRVGVCLTDAGAKALLVSPALAAAAPD
AAPALTPADLDAGTPADAPVPDPRAAGLTPEHPAYLIYTSGSTGVPKGIVISHANICHFLRSGNALYGMRADDVVFQGAS
VAFDLSMEEIWVPYLVGATLFVASPAMMGDLESLPGILEAEGITVLDTVPTLLAMISGDLPRVRLVLLGGEALPEPLIAR
WATGGRQLFNTYGPTEATVVATAAEMRPGEPVTIGGPIPNYSVYVAGEDLSLLGRDQQGELLIGGPGVARGYLARPELTA
EKFIANPFASDGTDPVLYRSGDAVSLDAAGRIVFHGRIDDQVKIRGFRVELGEIESRIRAVPDINQAAVVLRQDDGVDRL
VAFLIPERGRSIDAAALRRTLAGQMPPYMVPGHFEVAETLPRLTSGKVDRKALKIAPLTVVAADGEQEPPANETEAALVA
AAKQIFGNQPIALEGDFFSDLGGHSLLAARFVSAVRENPPLAGITLPDVYALRTVRAMADALIARTGGMGAGAATRDLSF
EPPPLLRRALCGLAQLVALPFVIALATAQWLGMFVTYLLLTGGGLSFFAELGVLLLVYVAINGVTAVAAVAGKWLILGRT
RPGRYPLWGTYYYRWWLAQRLAPLVHVKWLQGSPAIAIYLRLMGAKVGRDTLISDIEIGAPDLLTIGDGASLGGRLVIAN
AEIVGNELVIGTAEIGADAAVGTSCVISHDTVIGPQAEIADLTTIPAGSRVGAAERWDGSPGRKVGMAEPSDLPAPAEAS
FARRAAFLAAYVVLLGAIPAVGLLPIFPAFFIFDQISDSLSDITDVDYHWYLPILTWPTAMLMTAGTVLLIAGIRWIVLP
RTRSGTYSVHSLFYLRKWSLALAVEVTLETLSSLFATVYMRAWYRLMGANMGHGAEISTNLAGRYDLAEVGAKNFVADEV
VYGEEEIRRGWMHLEPTRTGARVFVGNDAVVPPGAVIPDDVLIGIKSKPPENAAMSPGETWFGSPPIRLPARQKVDLGST
AQTYEPGAWPKIRRGVFEAFATSFSPMLYITLAITAIDWYFYPAILEQDWWGLAYSFVGASVAIALIQSSAVIAMKWLLM
GVYKPGMQPMWSWWAMRTEAIAVAYWGLAGKVLLEHLQGTPFLPWVLRLFGVKVGKGVCMLTTDITEFDCVTIGDYATIN
RVSALQTHLYEDRIMKIGRVVVGRGVSVGAFSTVLYDTKVGDYARLRPLTIVMKGESIPANTEWEGAPAVPVVHRA

Sequences:

>Translated_1356_residues
MSDVAEKTRPGPAAGEPAPLGNAAAILRGDHRPDLIRDEVLAEIFLHSAATRPGHPCLVDGARVEAGGVHPHLTYADVAA
RAGRIAAGLAHRGIGPGDVVGLWMARGPDLLVAQIGITMSGAAWLPFDAEAPADRVGVCLTDAGAKALLVSPALAAAAPD
AAPALTPADLDAGTPADAPVPDPRAAGLTPEHPAYLIYTSGSTGVPKGIVISHANICHFLRSGNALYGMRADDVVFQGAS
VAFDLSMEEIWVPYLVGATLFVASPAMMGDLESLPGILEAEGITVLDTVPTLLAMISGDLPRVRLVLLGGEALPEPLIAR
WATGGRQLFNTYGPTEATVVATAAEMRPGEPVTIGGPIPNYSVYVAGEDLSLLGRDQQGELLIGGPGVARGYLARPELTA
EKFIANPFASDGTDPVLYRSGDAVSLDAAGRIVFHGRIDDQVKIRGFRVELGEIESRIRAVPDINQAAVVLRQDDGVDRL
VAFLIPERGRSIDAAALRRTLAGQMPPYMVPGHFEVAETLPRLTSGKVDRKALKIAPLTVVAADGEQEPPANETEAALVA
AAKQIFGNQPIALEGDFFSDLGGHSLLAARFVSAVRENPPLAGITLPDVYALRTVRAMADALIARTGGMGAGAATRDLSF
EPPPLLRRALCGLAQLVALPFVIALATAQWLGMFVTYLLLTGGGLSFFAELGVLLLVYVAINGVTAVAAVAGKWLILGRT
RPGRYPLWGTYYYRWWLAQRLAPLVHVKWLQGSPAIAIYLRLMGAKVGRDTLISDIEIGAPDLLTIGDGASLGGRLVIAN
AEIVGNELVIGTAEIGADAAVGTSCVISHDTVIGPQAEIADLTTIPAGSRVGAAERWDGSPGRKVGMAEPSDLPAPAEAS
FARRAAFLAAYVVLLGAIPAVGLLPIFPAFFIFDQISDSLSDITDVDYHWYLPILTWPTAMLMTAGTVLLIAGIRWIVLP
RTRSGTYSVHSLFYLRKWSLALAVEVTLETLSSLFATVYMRAWYRLMGANMGHGAEISTNLAGRYDLAEVGAKNFVADEV
VYGEEEIRRGWMHLEPTRTGARVFVGNDAVVPPGAVIPDDVLIGIKSKPPENAAMSPGETWFGSPPIRLPARQKVDLGST
AQTYEPGAWPKIRRGVFEAFATSFSPMLYITLAITAIDWYFYPAILEQDWWGLAYSFVGASVAIALIQSSAVIAMKWLLM
GVYKPGMQPMWSWWAMRTEAIAVAYWGLAGKVLLEHLQGTPFLPWVLRLFGVKVGKGVCMLTTDITEFDCVTIGDYATIN
RVSALQTHLYEDRIMKIGRVVVGRGVSVGAFSTVLYDTKVGDYARLRPLTIVMKGESIPANTEWEGAPAVPVVHRA
>Mature_1355_residues
SDVAEKTRPGPAAGEPAPLGNAAAILRGDHRPDLIRDEVLAEIFLHSAATRPGHPCLVDGARVEAGGVHPHLTYADVAAR
AGRIAAGLAHRGIGPGDVVGLWMARGPDLLVAQIGITMSGAAWLPFDAEAPADRVGVCLTDAGAKALLVSPALAAAAPDA
APALTPADLDAGTPADAPVPDPRAAGLTPEHPAYLIYTSGSTGVPKGIVISHANICHFLRSGNALYGMRADDVVFQGASV
AFDLSMEEIWVPYLVGATLFVASPAMMGDLESLPGILEAEGITVLDTVPTLLAMISGDLPRVRLVLLGGEALPEPLIARW
ATGGRQLFNTYGPTEATVVATAAEMRPGEPVTIGGPIPNYSVYVAGEDLSLLGRDQQGELLIGGPGVARGYLARPELTAE
KFIANPFASDGTDPVLYRSGDAVSLDAAGRIVFHGRIDDQVKIRGFRVELGEIESRIRAVPDINQAAVVLRQDDGVDRLV
AFLIPERGRSIDAAALRRTLAGQMPPYMVPGHFEVAETLPRLTSGKVDRKALKIAPLTVVAADGEQEPPANETEAALVAA
AKQIFGNQPIALEGDFFSDLGGHSLLAARFVSAVRENPPLAGITLPDVYALRTVRAMADALIARTGGMGAGAATRDLSFE
PPPLLRRALCGLAQLVALPFVIALATAQWLGMFVTYLLLTGGGLSFFAELGVLLLVYVAINGVTAVAAVAGKWLILGRTR
PGRYPLWGTYYYRWWLAQRLAPLVHVKWLQGSPAIAIYLRLMGAKVGRDTLISDIEIGAPDLLTIGDGASLGGRLVIANA
EIVGNELVIGTAEIGADAAVGTSCVISHDTVIGPQAEIADLTTIPAGSRVGAAERWDGSPGRKVGMAEPSDLPAPAEASF
ARRAAFLAAYVVLLGAIPAVGLLPIFPAFFIFDQISDSLSDITDVDYHWYLPILTWPTAMLMTAGTVLLIAGIRWIVLPR
TRSGTYSVHSLFYLRKWSLALAVEVTLETLSSLFATVYMRAWYRLMGANMGHGAEISTNLAGRYDLAEVGAKNFVADEVV
YGEEEIRRGWMHLEPTRTGARVFVGNDAVVPPGAVIPDDVLIGIKSKPPENAAMSPGETWFGSPPIRLPARQKVDLGSTA
QTYEPGAWPKIRRGVFEAFATSFSPMLYITLAITAIDWYFYPAILEQDWWGLAYSFVGASVAIALIQSSAVIAMKWLLMG
VYKPGMQPMWSWWAMRTEAIAVAYWGLAGKVLLEHLQGTPFLPWVLRLFGVKVGKGVCMLTTDITEFDCVTIGDYATINR
VSALQTHLYEDRIMKIGRVVVGRGVSVGAFSTVLYDTKVGDYARLRPLTIVMKGESIPANTEWEGAPAVPVVHRA

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI187761345, Length=547, Percent_Identity=25.4113345521024, Blast_Score=121, Evalue=4e-27,
Organism=Homo sapiens, GI187761343, Length=547, Percent_Identity=25.4113345521024, Blast_Score=121, Evalue=4e-27,
Organism=Homo sapiens, GI45580730, Length=443, Percent_Identity=25.0564334085779, Blast_Score=108, Evalue=5e-23,
Organism=Homo sapiens, GI38505220, Length=522, Percent_Identity=23.3716475095785, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI122937307, Length=518, Percent_Identity=22.5868725868726, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI115511026, Length=477, Percent_Identity=23.8993710691824, Blast_Score=88, Evalue=6e-17,
Organism=Homo sapiens, GI227499619, Length=215, Percent_Identity=31.1627906976744, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI42544132, Length=360, Percent_Identity=23.3333333333333, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI13236579, Length=495, Percent_Identity=25.4545454545455, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI157311624, Length=494, Percent_Identity=22.6720647773279, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI157311622, Length=494, Percent_Identity=22.6720647773279, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI58082049, Length=491, Percent_Identity=21.3849287169043, Blast_Score=73, Evalue=2e-12,
Organism=Escherichia coli, GI1786801, Length=588, Percent_Identity=33.1632653061224, Blast_Score=248, Evalue=1e-66,
Organism=Escherichia coli, GI221142682, Length=501, Percent_Identity=24.9500998003992, Blast_Score=100, Evalue=7e-22,
Organism=Escherichia coli, GI145693145, Length=386, Percent_Identity=25.6476683937824, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1786810, Length=518, Percent_Identity=25.6756756756757, Blast_Score=97, Evalue=7e-21,
Organism=Escherichia coli, GI1788107, Length=559, Percent_Identity=25.0447227191413, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1790505, Length=529, Percent_Identity=24.5746691871456, Blast_Score=81, Evalue=5e-16,
Organism=Escherichia coli, GI1789201, Length=371, Percent_Identity=26.4150943396226, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17556356, Length=530, Percent_Identity=26.6037735849057, Blast_Score=128, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32564420, Length=369, Percent_Identity=28.1842818428184, Blast_Score=100, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI32564422, Length=369, Percent_Identity=28.1842818428184, Blast_Score=100, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17531443, Length=546, Percent_Identity=24.3589743589744, Blast_Score=98, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17557194, Length=541, Percent_Identity=22.365988909427, Blast_Score=98, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17538037, Length=568, Percent_Identity=22.1830985915493, Blast_Score=97, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=410, Percent_Identity=23.6585365853659, Blast_Score=86, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32563687, Length=509, Percent_Identity=22.9862475442043, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71985884, Length=365, Percent_Identity=24.6575342465753, Blast_Score=84, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17558820, Length=501, Percent_Identity=23.3532934131737, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559526, Length=374, Percent_Identity=23.7967914438503, Blast_Score=80, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6319591, Length=705, Percent_Identity=23.5460992907801, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6319264, Length=557, Percent_Identity=23.5188509874327, Blast_Score=79, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6323182, Length=609, Percent_Identity=22.9885057471264, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648676, Length=574, Percent_Identity=28.2229965156794, Blast_Score=166, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24582852, Length=375, Percent_Identity=26.1333333333333, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI62472339, Length=584, Percent_Identity=22.2602739726027, Blast_Score=80, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24667955, Length=584, Percent_Identity=22.2602739726027, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24667959, Length=413, Percent_Identity=23.0024213075061, Blast_Score=77, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 144251; Mature: 144120

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS50075 ACP_DOMAIN ; PS00178 AA_TRNA_LIGASE_I ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVAEKTRPGPAAGEPAPLGNAAAILRGDHRPDLIRDEVLAEIFLHSAATRPGHPCLVD
CCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEE
GARVEAGGVHPHLTYADVAARAGRIAAGLAHRGIGPGDVVGLWMARGPDLLVAQIGITMS
CCEEECCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCHHHEEEHHHCCCCEEEEEECEEEC
GAAWLPFDAEAPADRVGVCLTDAGAKALLVSPALAAAAPDAAPALTPADLDAGTPADAPV
CCEECCCCCCCCCCCCEEEEECCCCCEEEECCHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PDPRAAGLTPEHPAYLIYTSGSTGVPKGIVISHANICHFLRSGNALYGMRADDVVFQGAS
CCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECHHHHHHHHCCCEEEECCCCCEEECCCC
VAFDLSMEEIWVPYLVGATLFVASPAMMGDLESLPGILEAEGITVLDTVPTLLAMISGDL
EEEECCHHHHHHHHHHHHHHHHHCCHHHCCHHHCCCCEECCCEEEEHHHHHHHHHHCCCC
PRVRLVLLGGEALPEPLIARWATGGRQLFNTYGPTEATVVATAAEMRPGEPVTIGGPIPN
CEEEEEEECCCCCCHHHHHHHCCCCHHHHHCCCCCCEEEEEEHHHCCCCCCEEECCCCCC
YSVYVAGEDLSLLGRDQQGELLIGGPGVARGYLARPELTAEKFIANPFASDGTDPVLYRS
CEEEEECCCHHEECCCCCCCEEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEC
GDAVSLDAAGRIVFHGRIDDQVKIRGFRVELGEIESRIRAVPDINQAAVVLRQDDGVDRL
CCEEEECCCCEEEEECCCCCEEEEEEEEEEHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
VAFLIPERGRSIDAAALRRTLAGQMPPYMVPGHFEVAETLPRLTSGKVDRKALKIAPLTV
HHHHCCCCCCCCCHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHCCCCCCCEEEEEEEEE
VAADGEQEPPANETEAALVAAAKQIFGNQPIALEGDFFSDLGGHSLLAARFVSAVRENPP
EECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCHHHCCCCHHHHHHHHHHHHHCCCC
LAGITLPDVYALRTVRAMADALIARTGGMGAGAATRDLSFEPPPLLRRALCGLAQLVALP
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FVIALATAQWLGMFVTYLLLTGGGLSFFAELGVLLLVYVAINGVTAVAAVAGKWLILGRT
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEECC
RPGRYPLWGTYYYRWWLAQRLAPLVHVKWLQGSPAIAIYLRLMGAKVGRDTLISDIEIGA
CCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCHHHHCCCCCCC
PDLLTIGDGASLGGRLVIANAEIVGNELVIGTAEIGADAAVGTSCVISHDTVIGPQAEIA
CCEEEECCCCCCCCEEEEEECEEECCEEEEEECCCCCCCCCCCEEEEECCCEECCCCHHH
DLTTIPAGSRVGAAERWDGSPGRKVGMAEPSDLPAPAEASFARRAAFLAAYVVLLGAIPA
HEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VGLLPIFPAFFIFDQISDSLSDITDVDYHWYLPILTWPTAMLMTAGTVLLIAGIRWIVLP
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEE
RTRSGTYSVHSLFYLRKWSLALAVEVTLETLSSLFATVYMRAWYRLMGANMGHGAEISTN
CCCCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
LAGRYDLAEVGAKNFVADEVVYGEEEIRRGWMHLEPTRTGARVFVGNDAVVPPGAVIPDD
CCCCCCHHHHCCCHHHHHHHHCCHHHHHCCCEEECCCCCCCEEEECCCCCCCCCCCCCCC
VLIGIKSKPPENAAMSPGETWFGSPPIRLPARQKVDLGSTAQTYEPGAWPKIRRGVFEAF
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ATSFSPMLYITLAITAIDWYFYPAILEQDWWGLAYSFVGASVAIALIQSSAVIAMKWLLM
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GVYKPGMQPMWSWWAMRTEAIAVAYWGLAGKVLLEHLQGTPFLPWVLRLFGVKVGKGVCM
HHHCCCCCHHHHHHHHHHHEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEE
LTTDITEFDCVTIGDYATINRVSALQTHLYEDRIMKIGRVVVGRGVSVGAFSTVLYDTKV
EEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEECCC
GDYARLRPLTIVMKGESIPANTEWEGAPAVPVVHRA
CCCHHCCEEEEEEECCCCCCCCCCCCCCCCCCEECC
>Mature Secondary Structure 
SDVAEKTRPGPAAGEPAPLGNAAAILRGDHRPDLIRDEVLAEIFLHSAATRPGHPCLVD
CCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEE
GARVEAGGVHPHLTYADVAARAGRIAAGLAHRGIGPGDVVGLWMARGPDLLVAQIGITMS
CCEEECCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCHHHEEEHHHCCCCEEEEEECEEEC
GAAWLPFDAEAPADRVGVCLTDAGAKALLVSPALAAAAPDAAPALTPADLDAGTPADAPV
CCEECCCCCCCCCCCCEEEEECCCCCEEEECCHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PDPRAAGLTPEHPAYLIYTSGSTGVPKGIVISHANICHFLRSGNALYGMRADDVVFQGAS
CCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECHHHHHHHHCCCEEEECCCCCEEECCCC
VAFDLSMEEIWVPYLVGATLFVASPAMMGDLESLPGILEAEGITVLDTVPTLLAMISGDL
EEEECCHHHHHHHHHHHHHHHHHCCHHHCCHHHCCCCEECCCEEEEHHHHHHHHHHCCCC
PRVRLVLLGGEALPEPLIARWATGGRQLFNTYGPTEATVVATAAEMRPGEPVTIGGPIPN
CEEEEEEECCCCCCHHHHHHHCCCCHHHHHCCCCCCEEEEEEHHHCCCCCCEEECCCCCC
YSVYVAGEDLSLLGRDQQGELLIGGPGVARGYLARPELTAEKFIANPFASDGTDPVLYRS
CEEEEECCCHHEECCCCCCCEEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEC
GDAVSLDAAGRIVFHGRIDDQVKIRGFRVELGEIESRIRAVPDINQAAVVLRQDDGVDRL
CCEEEECCCCEEEEECCCCCEEEEEEEEEEHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
VAFLIPERGRSIDAAALRRTLAGQMPPYMVPGHFEVAETLPRLTSGKVDRKALKIAPLTV
HHHHCCCCCCCCCHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHCCCCCCCEEEEEEEEE
VAADGEQEPPANETEAALVAAAKQIFGNQPIALEGDFFSDLGGHSLLAARFVSAVRENPP
EECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCHHHCCCCHHHHHHHHHHHHHCCCC
LAGITLPDVYALRTVRAMADALIARTGGMGAGAATRDLSFEPPPLLRRALCGLAQLVALP
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FVIALATAQWLGMFVTYLLLTGGGLSFFAELGVLLLVYVAINGVTAVAAVAGKWLILGRT
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEECC
RPGRYPLWGTYYYRWWLAQRLAPLVHVKWLQGSPAIAIYLRLMGAKVGRDTLISDIEIGA
CCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCHHHHCCCCCCC
PDLLTIGDGASLGGRLVIANAEIVGNELVIGTAEIGADAAVGTSCVISHDTVIGPQAEIA
CCEEEECCCCCCCCEEEEEECEEECCEEEEEECCCCCCCCCCCEEEEECCCEECCCCHHH
DLTTIPAGSRVGAAERWDGSPGRKVGMAEPSDLPAPAEASFARRAAFLAAYVVLLGAIPA
HEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VGLLPIFPAFFIFDQISDSLSDITDVDYHWYLPILTWPTAMLMTAGTVLLIAGIRWIVLP
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEE
RTRSGTYSVHSLFYLRKWSLALAVEVTLETLSSLFATVYMRAWYRLMGANMGHGAEISTN
CCCCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
LAGRYDLAEVGAKNFVADEVVYGEEEIRRGWMHLEPTRTGARVFVGNDAVVPPGAVIPDD
CCCCCCHHHHCCCHHHHHHHHCCHHHHHCCCEEECCCCCCCEEEECCCCCCCCCCCCCCC
VLIGIKSKPPENAAMSPGETWFGSPPIRLPARQKVDLGSTAQTYEPGAWPKIRRGVFEAF
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ATSFSPMLYITLAITAIDWYFYPAILEQDWWGLAYSFVGASVAIALIQSSAVIAMKWLLM
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GVYKPGMQPMWSWWAMRTEAIAVAYWGLAGKVLLEHLQGTPFLPWVLRLFGVKVGKGVCM
HHHCCCCCHHHHHHHHHHHEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEE
LTTDITEFDCVTIGDYATINRVSALQTHLYEDRIMKIGRVVVGRGVSVGAFSTVLYDTKV
EEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEECCC
GDYARLRPLTIVMKGESIPANTEWEGAPAVPVVHRA
CCCHHCCEEEEEEECCCCCCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA