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The map label for this gene is kup3 [H]

Identifier: 170751834

GI number: 170751834

Start: 5777865

End: 5779853

Strand: Direct

Name: kup3 [H]

Synonym: Mrad2831_5466

Alternate gene names: 170751834

Gene position: 5777865-5779853 (Clockwise)

Preceding gene: 170751833

Following gene: 170751835

Centisome position: 95.06

GC content: 70.54

Gene sequence:

>1989_bases
GTGAGCCAAGCTCTGCCTTCCGCGGCTGCCCAGGCGGTCGACCTTCCGGCGGCGCCGGTGGCGCGCAAGCCCGGCGCGAC
CCGCCACGGGCCGGGCGCCGCGCTCATGCTGGGCGCGCTGGGCGTCGTGTACGGCGACATCGGCACGAGCCCGCTCTACG
CGTTCAAGGAGGCGGTGAAGGCGGCGACCGCGGGCGGCGCCTCGGTGCCGGCAGCCGCCACGGGCGCGGTGTCGCTGATC
CTGTGGGCGCTGATCCTGATCGTGTCGCTGAAATACGCGGTGCTGATCCTGCGGGCCGACAACCGCGGCGAGGGCGGCAT
CGTCGCCATGCTGGCGCTGCTCGGCGCCCGTCAGGCCCGGCCGGGCACGTGGAAGGCGCTGCTCCTGGTGGTCGGGCTGG
TGGGCGCGGCCCTGCTCTACGGCGACGGCGCGATCACGCCGGCGATCTCGGTCCTGTCGGCCATCGAGGGGCTGAAGGTC
GACGCGCCGGCGCTCGGGCCGTACGTCGTGCCGATCACCCTCGCCATCCTGGTCGGTCTGTTCCTCGTCCAGCACAAGGG
CGTGGCCGCCATCGGCCGGGTCTTCGGACCCGTCATGCTCGTCTGGTTCGTCGTCCTGGTCCTGCTCGCTCTCCCGAGCA
TCCTGCGCGCGCCGGAGATCCTGTCGGCGGCCAACCCGGTCCGGGCGGTGGACTTCCTGATCCATGCCGGCTGGCACGTC
AGCTTCCTGATGCTGGGCGCGGCGTTCCTGGCGGTGACCGGCGGCGAGGCGATGTACGCCGATCTCGGCCATTTCGGCGC
CCCGGCGATCCGGATCGCGTGGTTCGGCCTCGTCCTGCCGGCGCTGCTGATCCACTATTGCGGGCAGGGCGCGCTGATCA
TCGCCGACCCGAGCGCGATCGAGAATCCGTTCTACCGGCTCGCGCCGGACTGGGCGCATTACCCTCTGGTGGCGCTCGCC
ACGATGGCGACCGTCATCGCCTCGCAGGCGGTGATCTCGGGCGTCTACTCGCTCACCCAGCAGTCGATCCAGCTCGGCTT
CATGCCGATGATGCGGGTGGTGCACACCGACGAGGACGAGCGCGGCCAGATCTACGTGCCGGCGGTGAACTGGCTGCTCG
CCGCGGCGACCCTGACGGCCGTGGTGGTGTTCGGCTCCTCCGACGCGCTCGCCGGCGCCTACGGCATCGCGGTCTCGGCC
CTGATGGGCATCACGACGCTGCTCGCCGCGCTGATCGCGCTCCGCTGGGGCTACAACCCGCTCCTGGTCTTCGCGGTCAA
CGGCTTCTTCCTCGGCATCGACCTCGTGTTCTTCGCCGCCAACAGCGTGAAGCTGTTCGAGGGTGGCTGGTTTCCGCTGC
TGCTCGCCGCCGCGGTCGCCTTCCTGATGCTGACCTGGATGAAGGGCAACCTCGTCCTCGAGTCGGTCCGGCAGACCATG
CGCATGTCCGAGGCGGCCTTCCTGTCCAGCCTCAGCTCGCACCCGCCGGTGACGCTGCCCGGCACCGCGGCCTTCCTGAC
CGCCGCCACCGAGGGCATCCCGATGGCGCTCGGCCGCCTGCTGGAGCGCAGCCGCTGCCTGCACGAGCGGATCCTGCTGA
TCACCGTCGTCTACGAGGAGGAGCCGGTGATCCCGGCGAGCGAGCGGGCGCAGGTCACGCTGGTGGCGCAGGGGATCCGC
AAGGCGATCTCGAAATACACGCCCGGCATGGAGCGCGTCGTGCTGCGCTACGGCTTCATGCAGATTGCCTCGATTCCCGA
GGGGCTGCAATGCGCGGTGGCGAGCGGGCTGCTGCCGCCGGAATATCTCGAGGACATGACCTACTTCGTCGGCCACGAGG
TGGTGATCCCGTCGCCGACCCATCCCGGCATGGCGCCGTGGCGGGAGGGCCTGTTCGCCTTCATGAAGCGGAACGCCGAG
CGCACCGGCGCCCATTTCGGCCTGCCGACCCGGCAGATCGTCGAGGTCGGCACCGAGATCGAGATCTGA

Upstream 100 bases:

>100_bases
GTGTTCGTCGCGGTCGCTCGCGAGATCTGCCGAGTCTATCGCCGAACGCGCGACTCGCTAAGATTTCGCCCCACAGCGAC
GCCATCGACCGGACCCGACC

Downstream 100 bases:

>100_bases
CCGGCCGCGGCGCGCGGGGACCGCGCTGCGGAGGCCGAGGCCGGCCGTCTTTCGCATTGAAAACGGCCCCGTTCGCCAGC
ATATCGCCACCGCAATTTCC

Product: K potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 661

Protein sequence:

>662_residues
MSQALPSAAAQAVDLPAAPVARKPGATRHGPGAALMLGALGVVYGDIGTSPLYAFKEAVKAATAGGASVPAAATGAVSLI
LWALILIVSLKYAVLILRADNRGEGGIVAMLALLGARQARPGTWKALLLVVGLVGAALLYGDGAITPAISVLSAIEGLKV
DAPALGPYVVPITLAILVGLFLVQHKGVAAIGRVFGPVMLVWFVVLVLLALPSILRAPEILSAANPVRAVDFLIHAGWHV
SFLMLGAAFLAVTGGEAMYADLGHFGAPAIRIAWFGLVLPALLIHYCGQGALIIADPSAIENPFYRLAPDWAHYPLVALA
TMATVIASQAVISGVYSLTQQSIQLGFMPMMRVVHTDEDERGQIYVPAVNWLLAAATLTAVVVFGSSDALAGAYGIAVSA
LMGITTLLAALIALRWGYNPLLVFAVNGFFLGIDLVFFAANSVKLFEGGWFPLLLAAAVAFLMLTWMKGNLVLESVRQTM
RMSEAAFLSSLSSHPPVTLPGTAAFLTAATEGIPMALGRLLERSRCLHERILLITVVYEEEPVIPASERAQVTLVAQGIR
KAISKYTPGMERVVLRYGFMQIASIPEGLQCAVASGLLPPEYLEDMTYFVGHEVVIPSPTHPGMAPWREGLFAFMKRNAE
RTGAHFGLPTRQIVEVGTEIEI

Sequences:

>Translated_662_residues
MSQALPSAAAQAVDLPAAPVARKPGATRHGPGAALMLGALGVVYGDIGTSPLYAFKEAVKAATAGGASVPAAATGAVSLI
LWALILIVSLKYAVLILRADNRGEGGIVAMLALLGARQARPGTWKALLLVVGLVGAALLYGDGAITPAISVLSAIEGLKV
DAPALGPYVVPITLAILVGLFLVQHKGVAAIGRVFGPVMLVWFVVLVLLALPSILRAPEILSAANPVRAVDFLIHAGWHV
SFLMLGAAFLAVTGGEAMYADLGHFGAPAIRIAWFGLVLPALLIHYCGQGALIIADPSAIENPFYRLAPDWAHYPLVALA
TMATVIASQAVISGVYSLTQQSIQLGFMPMMRVVHTDEDERGQIYVPAVNWLLAAATLTAVVVFGSSDALAGAYGIAVSA
LMGITTLLAALIALRWGYNPLLVFAVNGFFLGIDLVFFAANSVKLFEGGWFPLLLAAAVAFLMLTWMKGNLVLESVRQTM
RMSEAAFLSSLSSHPPVTLPGTAAFLTAATEGIPMALGRLLERSRCLHERILLITVVYEEEPVIPASERAQVTLVAQGIR
KAISKYTPGMERVVLRYGFMQIASIPEGLQCAVASGLLPPEYLEDMTYFVGHEVVIPSPTHPGMAPWREGLFAFMKRNAE
RTGAHFGLPTRQIVEVGTEIEI
>Mature_661_residues
SQALPSAAAQAVDLPAAPVARKPGATRHGPGAALMLGALGVVYGDIGTSPLYAFKEAVKAATAGGASVPAAATGAVSLIL
WALILIVSLKYAVLILRADNRGEGGIVAMLALLGARQARPGTWKALLLVVGLVGAALLYGDGAITPAISVLSAIEGLKVD
APALGPYVVPITLAILVGLFLVQHKGVAAIGRVFGPVMLVWFVVLVLLALPSILRAPEILSAANPVRAVDFLIHAGWHVS
FLMLGAAFLAVTGGEAMYADLGHFGAPAIRIAWFGLVLPALLIHYCGQGALIIADPSAIENPFYRLAPDWAHYPLVALAT
MATVIASQAVISGVYSLTQQSIQLGFMPMMRVVHTDEDERGQIYVPAVNWLLAAATLTAVVVFGSSDALAGAYGIAVSAL
MGITTLLAALIALRWGYNPLLVFAVNGFFLGIDLVFFAANSVKLFEGGWFPLLLAAAVAFLMLTWMKGNLVLESVRQTMR
MSEAAFLSSLSSHPPVTLPGTAAFLTAATEGIPMALGRLLERSRCLHERILLITVVYEEEPVIPASERAQVTLVAQGIRK
AISKYTPGMERVVLRYGFMQIASIPEGLQCAVASGLLPPEYLEDMTYFVGHEVVIPSPTHPGMAPWREGLFAFMKRNAER
TGAHFGLPTRQIVEVGTEIEI

Specific function: Transport of potassium into the cell [H]

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family [H]

Homologues:

Organism=Escherichia coli, GI48994960, Length=643, Percent_Identity=42.457231726283, Blast_Score=501, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003855
- InterPro:   IPR023051 [H]

Pfam domain/function: PF02705 K_trans [H]

EC number: NA

Molecular weight: Translated: 69811; Mature: 69680

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQALPSAAAQAVDLPAAPVARKPGATRHGPGAALMLGALGVVYGDIGTSPLYAFKEAVK
CCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AATAGGASVPAAATGAVSLILWALILIVSLKYAVLILRADNRGEGGIVAMLALLGARQAR
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCCC
PGTWKALLLVVGLVGAALLYGDGAITPAISVLSAIEGLKVDAPALGPYVVPITLAILVGL
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
FLVQHKGVAAIGRVFGPVMLVWFVVLVLLALPSILRAPEILSAANPVRAVDFLIHAGWHV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCHHH
SFLMLGAAFLAVTGGEAMYADLGHFGAPAIRIAWFGLVLPALLIHYCGQGALIIADPSAI
HHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHH
ENPFYRLAPDWAHYPLVALATMATVIASQAVISGVYSLTQQSIQLGFMPMMRVVHTDEDE
CCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RGQIYVPAVNWLLAAATLTAVVVFGSSDALAGAYGIAVSALMGITTLLAALIALRWGYNP
CCEEEEHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LLVFAVNGFFLGIDLVFFAANSVKLFEGGWFPLLLAAAVAFLMLTWMKGNLVLESVRQTM
EEEEEECHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RMSEAAFLSSLSSHPPVTLPGTAAFLTAATEGIPMALGRLLERSRCLHERILLITVVYEE
HHHHHHHHHHHCCCCCEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEEEECC
EPVIPASERAQVTLVAQGIRKAISKYTPGMERVVLRYGFMQIASIPEGLQCAVASGLLPP
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCH
EYLEDMTYFVGHEVVIPSPTHPGMAPWREGLFAFMKRNAERTGAHFGLPTRQIVEVGTEI
HHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHCCCCC
EI
CC
>Mature Secondary Structure 
SQALPSAAAQAVDLPAAPVARKPGATRHGPGAALMLGALGVVYGDIGTSPLYAFKEAVK
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AATAGGASVPAAATGAVSLILWALILIVSLKYAVLILRADNRGEGGIVAMLALLGARQAR
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCCC
PGTWKALLLVVGLVGAALLYGDGAITPAISVLSAIEGLKVDAPALGPYVVPITLAILVGL
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
FLVQHKGVAAIGRVFGPVMLVWFVVLVLLALPSILRAPEILSAANPVRAVDFLIHAGWHV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCHHH
SFLMLGAAFLAVTGGEAMYADLGHFGAPAIRIAWFGLVLPALLIHYCGQGALIIADPSAI
HHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHH
ENPFYRLAPDWAHYPLVALATMATVIASQAVISGVYSLTQQSIQLGFMPMMRVVHTDEDE
CCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RGQIYVPAVNWLLAAATLTAVVVFGSSDALAGAYGIAVSALMGITTLLAALIALRWGYNP
CCEEEEHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LLVFAVNGFFLGIDLVFFAANSVKLFEGGWFPLLLAAAVAFLMLTWMKGNLVLESVRQTM
EEEEEECHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RMSEAAFLSSLSSHPPVTLPGTAAFLTAATEGIPMALGRLLERSRCLHERILLITVVYEE
HHHHHHHHHHHCCCCCEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEEEECC
EPVIPASERAQVTLVAQGIRKAISKYTPGMERVVLRYGFMQIASIPEGLQCAVASGLLPP
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCH
EYLEDMTYFVGHEVVIPSPTHPGMAPWREGLFAFMKRNAERTGAHFGLPTRQIVEVGTEI
HHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHCCCCC
EI
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]