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The map label for this gene is aphA [H]

Identifier: 170751603

GI number: 170751603

Start: 5542910

End: 5544034

Strand: Direct

Name: aphA [H]

Synonym: Mrad2831_5224

Alternate gene names: 170751603

Gene position: 5542910-5544034 (Clockwise)

Preceding gene: 170751598

Following gene: 170751604

Centisome position: 91.2

GC content: 69.16

Gene sequence:

>1125_bases
GTGGAGCGAGCCGCGAACCTCACCACGGACGACTTCCGCGCCCTCGCCGACGCCCTGCCCCAGATGGCCTGGGTCGCCGA
GCCGAACGGCGACATAATCTGGTACAACCAGCGCTGGTACGACTACACCGGCACCACCATCGAGCAGATGTTCGGCTGGG
GCTGGCGCGACGTCCACCACCCCGATCACGTCGAGCGCGTCGTGGAGCGCATCAGCGAGGCGTTCCGGACCGGCGAGCCA
TGGAAGGACACCTTCCCGCTCCGGGGCGCCGACGGCGAGTACCGCTGGTTCCTGTCGCTGGCACAACCCCATCGCGGGCC
GGACGGGGCCATCCTGCGCTGGTTCGGGACCAATACCGATATCACCGAGCGCAAGGGGCTGGAGCGCCGGCTCGCCCGCC
ACGCCATCGACCTGCGCCGATCCAACGAGGAACTGGAGCAGTTCGCCTACGTCGCCTCGCACGACCTTAAGGCGCCGCTG
CGCGGCATCGAGAACCTCGTCGGATGGATCGAGGAGGATCTCGAAGGCTCGCTGACCGGCGACGTCCTGACCAACATGGA
GTTGCTCAAAAGCCGGGTGCGGCGGCTCGACAGCCTGCTCGACGACCTCCTGGCCTACTCCAGGGCGGGACGGGCCGACG
CGGCGATGGACACGGTCGACACGAAGGCGCTCGTCGAGGAACTCGCCGTTCTGGTCAGCCCTCCCGAAGGCTTCGCGATC
ACGGCGGACGATTCCTTGCCGACGTTGCGGGCGGCCCGGGCCCCGCTGACCCAGGCCTTGCAGAACCTGATCGGCAACGC
CATCAAGCATCACGACCGCCCGGCCGAGGGGCACATCCGGGTCGAGGCCAAGCCTGCGGGGGACGCGGTCGAGTTCGTCG
TGACCGACGACGGGCCGGGCATCCCCGAGCAGTTCCGCGAGCGTGTCTTCGGCATGTTCCAGACGCTCAAGCCCCGCGAC
GAGGTCGAGGGCAGCGGCATGGGGCTGGCCATCGTGCGCAAGTTGGTCGACCGCCAGGGCGGCAAGGTCTGGCTCTCCGA
CGGGCCCGACGGGCGCGGCTTGGCGGTGCATTTCACGTGGCCGCGCGACGGCCGGAAGGGACACGCGGATGGGCTCGACG
GTTAA

Upstream 100 bases:

>100_bases
GCGTGTCGGTGATGGGCCCCCATGCATCGATGACGTAGCCTCACCGTGGGTGTATGCGCCTATCGCCGTAGCTTCGCTTG
CAAGACTGGGAGCCCCTCGC

Downstream 100 bases:

>100_bases
CATCCTGCTGGTCGACGACGACGAGGTCGACGTTCAGGGGCTCAAGCGCGCCTTCAAGAAGAGCAAGATCGGAAACCCGA
TCACGGTCGCCCGCGACGGC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MERAANLTTDDFRALADALPQMAWVAEPNGDIIWYNQRWYDYTGTTIEQMFGWGWRDVHHPDHVERVVERISEAFRTGEP
WKDTFPLRGADGEYRWFLSLAQPHRGPDGAILRWFGTNTDITERKGLERRLARHAIDLRRSNEELEQFAYVASHDLKAPL
RGIENLVGWIEEDLEGSLTGDVLTNMELLKSRVRRLDSLLDDLLAYSRAGRADAAMDTVDTKALVEELAVLVSPPEGFAI
TADDSLPTLRAARAPLTQALQNLIGNAIKHHDRPAEGHIRVEAKPAGDAVEFVVTDDGPGIPEQFRERVFGMFQTLKPRD
EVEGSGMGLAIVRKLVDRQGGKVWLSDGPDGRGLAVHFTWPRDGRKGHADGLDG

Sequences:

>Translated_374_residues
MERAANLTTDDFRALADALPQMAWVAEPNGDIIWYNQRWYDYTGTTIEQMFGWGWRDVHHPDHVERVVERISEAFRTGEP
WKDTFPLRGADGEYRWFLSLAQPHRGPDGAILRWFGTNTDITERKGLERRLARHAIDLRRSNEELEQFAYVASHDLKAPL
RGIENLVGWIEEDLEGSLTGDVLTNMELLKSRVRRLDSLLDDLLAYSRAGRADAAMDTVDTKALVEELAVLVSPPEGFAI
TADDSLPTLRAARAPLTQALQNLIGNAIKHHDRPAEGHIRVEAKPAGDAVEFVVTDDGPGIPEQFRERVFGMFQTLKPRD
EVEGSGMGLAIVRKLVDRQGGKVWLSDGPDGRGLAVHFTWPRDGRKGHADGLDG
>Mature_374_residues
MERAANLTTDDFRALADALPQMAWVAEPNGDIIWYNQRWYDYTGTTIEQMFGWGWRDVHHPDHVERVVERISEAFRTGEP
WKDTFPLRGADGEYRWFLSLAQPHRGPDGAILRWFGTNTDITERKGLERRLARHAIDLRRSNEELEQFAYVASHDLKAPL
RGIENLVGWIEEDLEGSLTGDVLTNMELLKSRVRRLDSLLDDLLAYSRAGRADAAMDTVDTKALVEELAVLVSPPEGFAI
TADDSLPTLRAARAPLTQALQNLIGNAIKHHDRPAEGHIRVEAKPAGDAVEFVVTDDGPGIPEQFRERVFGMFQTLKPRD
EVEGSGMGLAIVRKLVDRQGGKVWLSDGPDGRGLAVHFTWPRDGRKGHADGLDG

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=365, Percent_Identity=26.027397260274, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=28.4444444444444, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790861, Length=251, Percent_Identity=28.2868525896414, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082128, Length=208, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=28.2511210762332, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=26.1044176706827, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790346, Length=211, Percent_Identity=28.9099526066351, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786912, Length=218, Percent_Identity=28.4403669724771, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=219, Percent_Identity=25.1141552511416, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41916; Mature: 41916

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERAANLTTDDFRALADALPQMAWVAEPNGDIIWYNQRWYDYTGTTIEQMFGWGWRDVHH
CCCCCCCCHHHHHHHHHHHHHHEEEECCCCCEEEECCEEECCCCCHHHHHHCCCCCCCCC
PDHVERVVERISEAFRTGEPWKDTFPLRGADGEYRWFLSLAQPHRGPDGAILRWFGTNTD
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCC
ITERKGLERRLARHAIDLRRSNEELEQFAYVASHDLKAPLRGIENLVGWIEEDLEGSLTG
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCH
DVLTNMELLKSRVRRLDSLLDDLLAYSRAGRADAAMDTVDTKALVEELAVLVSPPEGFAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEE
TADDSLPTLRAARAPLTQALQNLIGNAIKHHDRPAEGHIRVEAKPAGDAVEFVVTDDGPG
ECCCCCCHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEECCCCC
IPEQFRERVFGMFQTLKPRDEVEGSGMGLAIVRKLVDRQGGKVWLSDGPDGRGLAVHFTW
CCHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEC
PRDGRKGHADGLDG
CCCCCCCCCCCCCC
>Mature Secondary Structure
MERAANLTTDDFRALADALPQMAWVAEPNGDIIWYNQRWYDYTGTTIEQMFGWGWRDVHH
CCCCCCCCHHHHHHHHHHHHHHEEEECCCCCEEEECCEEECCCCCHHHHHHCCCCCCCCC
PDHVERVVERISEAFRTGEPWKDTFPLRGADGEYRWFLSLAQPHRGPDGAILRWFGTNTD
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCC
ITERKGLERRLARHAIDLRRSNEELEQFAYVASHDLKAPLRGIENLVGWIEEDLEGSLTG
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCH
DVLTNMELLKSRVRRLDSLLDDLLAYSRAGRADAAMDTVDTKALVEELAVLVSPPEGFAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEE
TADDSLPTLRAARAPLTQALQNLIGNAIKHHDRPAEGHIRVEAKPAGDAVEFVVTDDGPG
ECCCCCCHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEECCCCC
IPEQFRERVFGMFQTLKPRDEVEGSGMGLAIVRKLVDRQGGKVWLSDGPDGRGLAVHFTW
CCHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEC
PRDGRKGHADGLDG
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]