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The map label for this gene is dppB [H]

Identifier: 170751463

GI number: 170751463

Start: 5398978

End: 5399922

Strand: Reverse

Name: dppB [H]

Synonym: Mrad2831_5082

Alternate gene names: 170751463

Gene position: 5399922-5398978 (Counterclockwise)

Preceding gene: 170751464

Following gene: 170751462

Centisome position: 88.85

GC content: 69.63

Gene sequence:

>945_bases
ATGCTGCGGTTCCTGGCGCGTCGCCTCGCCCTGGCGGTCCCGACCCTGATCCTCGCCTCGATGATCATCTTCGCCCTGCA
GCAATTGCTGCCGGGCGACGTCGCCACCGCGCTCACCGGCGAGGAGCGCGACCCGCAGGTGATCGCCTTCATCCGCGAGA
AGTACCACCTCGATGAGCCCCTGCCGGTGCGCTACGCGTACTGGGCCGGCGGCGTGCTGCGGGGCGATCTCGGCGAGTCG
ATCCGGCTGCAGAAGCCGGTCTCGGAGCTGATCGTCGAGAAGCTGCCGGTGACGCTGGAACTCGCCTGCCTCGCCATGCT
GGTGGCGCTCGCCATCGGCGTGCCCATGGGCGTGCTCTCGGCGGTCAGGCGCGGTCAGGCCGCCGACACGATCGCCAACG
GCGTGGCCCTCTGGGGGCTGTCGGTGCCCAATTTCTGGCTCGGGATCCTGCTGATCCTGCTGTTCTCGGTCGAGCTCGGC
TGGCTGCCGGCCTCCGGCTACGTCTCGCCCTTCGAGAGCCTGTCGGACAACCTCGCCGCCATGGTGATGCCGGCCTTCGT
GCTCGGCAACGCCATCGCGGCGGTGATGATGCGCCACACCCGCGCGGCGATGCTGGGCGTGCTGGGCTCCGACTACGTCC
GCACGGCCCGCGCCAAGGGCGTCTCGCCCCTGCGCGTTACCCTCCGGCACGCGCTGCCCAACGCCGCGATCCCGATCATC
ACCCTCGGCGCGCTGGAGTTCGGTCAGCTCCTGTCCGGGGCGGTGCTCACCGAGCAAGTGTTCTCCGTGCCGGGCTTCGG
CAAGCTGATGGTCGATGCCGTCTTCAACCGGGACTTCGCTACCGTGCAGGGCGTCGTGATCTGCACGGCGGCCACCTACA
TCGCCCTGAACCTCGCCGCCGACCTGCTCTCGGCCGCCGTCAATCCGAAGCTGAGGCGGGCATGA

Upstream 100 bases:

>100_bases
TCCTGCACCGCAAGCTGCTCTGGGCCTACAGCCAGAAGATCACGGGCTTCGTGCCCTACCCGGACGGGCTGGTGCGCTTC
ACCGGGCTGAAGCTGAACTG

Downstream 100 bases:

>100_bases
GCACCGGCAGCGAGATCGCCCGCGCCGAGGCGGTCGGCCTGGAGTCCGCCCCGTCCGGTACCCCCGCCCCCGCCATCCTT
CAGGAACCCGGCACCCTCGC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MLRFLARRLALAVPTLILASMIIFALQQLLPGDVATALTGEERDPQVIAFIREKYHLDEPLPVRYAYWAGGVLRGDLGES
IRLQKPVSELIVEKLPVTLELACLAMLVALAIGVPMGVLSAVRRGQAADTIANGVALWGLSVPNFWLGILLILLFSVELG
WLPASGYVSPFESLSDNLAAMVMPAFVLGNAIAAVMMRHTRAAMLGVLGSDYVRTARAKGVSPLRVTLRHALPNAAIPII
TLGALEFGQLLSGAVLTEQVFSVPGFGKLMVDAVFNRDFATVQGVVICTAATYIALNLAADLLSAAVNPKLRRA

Sequences:

>Translated_314_residues
MLRFLARRLALAVPTLILASMIIFALQQLLPGDVATALTGEERDPQVIAFIREKYHLDEPLPVRYAYWAGGVLRGDLGES
IRLQKPVSELIVEKLPVTLELACLAMLVALAIGVPMGVLSAVRRGQAADTIANGVALWGLSVPNFWLGILLILLFSVELG
WLPASGYVSPFESLSDNLAAMVMPAFVLGNAIAAVMMRHTRAAMLGVLGSDYVRTARAKGVSPLRVTLRHALPNAAIPII
TLGALEFGQLLSGAVLTEQVFSVPGFGKLMVDAVFNRDFATVQGVVICTAATYIALNLAADLLSAAVNPKLRRA
>Mature_314_residues
MLRFLARRLALAVPTLILASMIIFALQQLLPGDVATALTGEERDPQVIAFIREKYHLDEPLPVRYAYWAGGVLRGDLGES
IRLQKPVSELIVEKLPVTLELACLAMLVALAIGVPMGVLSAVRRGQAADTIANGVALWGLSVPNFWLGILLILLFSVELG
WLPASGYVSPFESLSDNLAAMVMPAFVLGNAIAAVMMRHTRAAMLGVLGSDYVRTARAKGVSPLRVTLRHALPNAAIPII
TLGALEFGQLLSGAVLTEQVFSVPGFGKLMVDAVFNRDFATVQGVVICTAATYIALNLAADLLSAAVNPKLRRA

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=42.2287390029325, Blast_Score=254, Evalue=6e-69,
Organism=Escherichia coli, GI1787053, Length=312, Percent_Identity=40.7051282051282, Blast_Score=244, Evalue=4e-66,
Organism=Escherichia coli, GI1789888, Length=316, Percent_Identity=36.7088607594937, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1787497, Length=314, Percent_Identity=34.0764331210191, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1787761, Length=316, Percent_Identity=37.9746835443038, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=32.089552238806, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1788504, Length=358, Percent_Identity=27.9329608938547, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33519; Mature: 33519

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFLARRLALAVPTLILASMIIFALQQLLPGDVATALTGEERDPQVIAFIREKYHLDEP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCC
LPVRYAYWAGGVLRGDLGESIRLQKPVSELIVEKLPVTLELACLAMLVALAIGVPMGVLS
CCCEEHHHCCCEEECCCCCCCCHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHH
AVRRGQAADTIANGVALWGLSVPNFWLGILLILLFSVELGWLPASGYVSPFESLSDNLAA
HHHCCCHHHHHHCCHHEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
MVMPAFVLGNAIAAVMMRHTRAAMLGVLGSDYVRTARAKGVSPLRVTLRHALPNAAIPII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHH
TLGALEFGQLLSGAVLTEQVFSVPGFGKLMVDAVFNRDFATVQGVVICTAATYIALNLAA
EEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
DLLSAAVNPKLRRA
HHHHHHCCCHHCCC
>Mature Secondary Structure
MLRFLARRLALAVPTLILASMIIFALQQLLPGDVATALTGEERDPQVIAFIREKYHLDEP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCC
LPVRYAYWAGGVLRGDLGESIRLQKPVSELIVEKLPVTLELACLAMLVALAIGVPMGVLS
CCCEEHHHCCCEEECCCCCCCCHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHH
AVRRGQAADTIANGVALWGLSVPNFWLGILLILLFSVELGWLPASGYVSPFESLSDNLAA
HHHCCCHHHHHHCCHHEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
MVMPAFVLGNAIAAVMMRHTRAAMLGVLGSDYVRTARAKGVSPLRVTLRHALPNAAIPII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHH
TLGALEFGQLLSGAVLTEQVFSVPGFGKLMVDAVFNRDFATVQGVVICTAATYIALNLAA
EEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
DLLSAAVNPKLRRA
HHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]