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The map label for this gene is yyaJ [H]

Identifier: 170751259

GI number: 170751259

Start: 5209559

End: 5210956

Strand: Reverse

Name: yyaJ [H]

Synonym: Mrad2831_4876

Alternate gene names: 170751259

Gene position: 5210956-5209559 (Counterclockwise)

Preceding gene: 170751261

Following gene: 170751258

Centisome position: 85.74

GC content: 77.18

Gene sequence:

>1398_bases
TTGGTCGACGCCCGAATCCAGGCCGCGCGCCTCTCCGACCCCCTCGCGCCGGTGGACGGGTCGGTCGCGGCCGTCACGCG
GCGGCTCGATTCCCTGCCGATCACGCGGCTCCACGCGGCGGCGCTCGCCGTCTGCACGCTGGGCCTGTTCACCGACATCG
CCGAGGTCGCCCTGAGCAACGCCCTGGCGGCCATCTTCCTCGCGCCGCCCCACAGCATGCCGCGGGGCAGCCTCTCCCTG
CTCCTCGCCTCCGTCTTCGCCGGCGGGGCCGTGGGCGCGCCCGTCTTCGGGATGCTGGGGGATCGCCTCGGCCGCGGGCG
CGCGCTCCAGGCCTCCCTCGCGCTGATGGCCGCCGGATCGCTGGCCGCGGCCGCGAGCCAGGGGCTCACGGCGCTGACGA
TCGCCCGCACGGTCTCGGGCTTCGCGATCGGCGGGTTCCCGCCCCTGGTCGCCACCTACCTCGCCGAGGTGACGCCCGCG
CGCCACCGCGGCGCGACGCTGCTGGTCTGCGCCGGCCTCGGGCTCCTCGGCGGCCTGGCCGCCATCGGCCTGGTCCAGAT
GCTCGCACCGGGCGCGCCGCTGGGGATCGAGCCGTGGCGCTGGGCGCTGATCCTCGGGGGCGCCCTGGCGGCGCTCGGCG
GCCTCCTGTTCGCGCGGCTGCCGGAATCGCCGCGGTGGCTCGCCTCGGTCGGGCGCTCCGCCGAGGCCGACGCCGCCTGC
CGCCGGTTCGAGCGGGCGGCCGGCCGGGTCCGGGTCGCCGCCCCCGCCGGCCCGGACCCGGCGCCAGCCGCGGCCGGGCC
GGCGGGGTTCCGCGGCCTGTTCGCCGGGCCGCGCCAGCTGCGCCGGACGGCGCTGTTCGTCGGGCTCTACACCCTCGCCC
CCCTGGCGACGATCGCCTTCCCGCTGCTCAGCGCCGTCGTGATGGTGGAGAAGGGGTTCAAGGTCGACCAATCCCTGGTC
TTCGCTGCCCTGTCGATGCTCGGGCCGCCGCTGGGTACCCTGCTGACCGCGCTGGTGATCGACCGGCTCGAGCGGCGCGC
CTGCCTGACGGCCCTGGCGGCGGCGATGGCGGCCCTCGGCACGGCCTTCGCCGCGAGCGGCACGTTCCTAACGCTGGTCC
TCGTCGGCATCGCGTTCAACACCGCCGCGGCGACCTACGGCAGCATCCTCGCCGTCTACGCGACGGAGCTGCTCCCGACG
CCGCTGCGGGCCTCGGCCATGACCTGCGCCTGGGCCGGCGGCCGGGTCGCCGCCGCGCTGGCGCCGATCATCCTCCTGCC
GGTCCTCTCGGCCTACGGGCCGCACGCGATGTTCGCGGTGATCACGGTCGTCCTCGCGGCGAGCGCGGCCCTGCTCCTCT
CCGGACCGCGCGGCCTGTCGGGGCGGGCCGTTGCGTAG

Upstream 100 bases:

>100_bases
TGCATTTGTGAACGCCATCGCGTTCCCCGGTGCGGAACACGCCGCTATGGCGGTGCGTCACCGGGTGCGCGCACGCTCCG
GTCGCAGAGGATCCACACGC

Downstream 100 bases:

>100_bases
GGAGCGCCAGAGGCGGCGCGGGCCTCCCGCAGGCGGGACCGGGGCGGATGGCGCCGGTTGCCGATCCGGCACGATTCACA
CGATAGGGTCGCGCAGGCGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MVDARIQAARLSDPLAPVDGSVAAVTRRLDSLPITRLHAAALAVCTLGLFTDIAEVALSNALAAIFLAPPHSMPRGSLSL
LLASVFAGGAVGAPVFGMLGDRLGRGRALQASLALMAAGSLAAAASQGLTALTIARTVSGFAIGGFPPLVATYLAEVTPA
RHRGATLLVCAGLGLLGGLAAIGLVQMLAPGAPLGIEPWRWALILGGALAALGGLLFARLPESPRWLASVGRSAEADAAC
RRFERAAGRVRVAAPAGPDPAPAAAGPAGFRGLFAGPRQLRRTALFVGLYTLAPLATIAFPLLSAVVMVEKGFKVDQSLV
FAALSMLGPPLGTLLTALVIDRLERRACLTALAAAMAALGTAFAASGTFLTLVLVGIAFNTAAATYGSILAVYATELLPT
PLRASAMTCAWAGGRVAAALAPIILLPVLSAYGPHAMFAVITVVLAASAALLLSGPRGLSGRAVA

Sequences:

>Translated_465_residues
MVDARIQAARLSDPLAPVDGSVAAVTRRLDSLPITRLHAAALAVCTLGLFTDIAEVALSNALAAIFLAPPHSMPRGSLSL
LLASVFAGGAVGAPVFGMLGDRLGRGRALQASLALMAAGSLAAAASQGLTALTIARTVSGFAIGGFPPLVATYLAEVTPA
RHRGATLLVCAGLGLLGGLAAIGLVQMLAPGAPLGIEPWRWALILGGALAALGGLLFARLPESPRWLASVGRSAEADAAC
RRFERAAGRVRVAAPAGPDPAPAAAGPAGFRGLFAGPRQLRRTALFVGLYTLAPLATIAFPLLSAVVMVEKGFKVDQSLV
FAALSMLGPPLGTLLTALVIDRLERRACLTALAAAMAALGTAFAASGTFLTLVLVGIAFNTAAATYGSILAVYATELLPT
PLRASAMTCAWAGGRVAAALAPIILLPVLSAYGPHAMFAVITVVLAASAALLLSGPRGLSGRAVA
>Mature_465_residues
MVDARIQAARLSDPLAPVDGSVAAVTRRLDSLPITRLHAAALAVCTLGLFTDIAEVALSNALAAIFLAPPHSMPRGSLSL
LLASVFAGGAVGAPVFGMLGDRLGRGRALQASLALMAAGSLAAAASQGLTALTIARTVSGFAIGGFPPLVATYLAEVTPA
RHRGATLLVCAGLGLLGGLAAIGLVQMLAPGAPLGIEPWRWALILGGALAALGGLLFARLPESPRWLASVGRSAEADAAC
RRFERAAGRVRVAAPAGPDPAPAAAGPAGFRGLFAGPRQLRRTALFVGLYTLAPLATIAFPLLSAVVMVEKGFKVDQSLV
FAALSMLGPPLGTLLTALVIDRLERRACLTALAAAMAALGTAFAASGTFLTLVLVGIAFNTAAATYGSILAVYATELLPT
PLRASAMTCAWAGGRVAAALAPIILLPVLSAYGPHAMFAVITVVLAASAALLLSGPRGLSGRAVA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24497497, Length=399, Percent_Identity=28.3208020050125, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI90669191, Length=358, Percent_Identity=29.8882681564246, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI7662270, Length=257, Percent_Identity=26.4591439688716, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI262399383, Length=160, Percent_Identity=31.25, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI213021148, Length=439, Percent_Identity=26.879271070615, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI73695465, Length=161, Percent_Identity=29.8136645962733, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788074, Length=427, Percent_Identity=28.5714285714286, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788068, Length=455, Percent_Identity=28.3516483516484, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI87082159, Length=420, Percent_Identity=28.3333333333333, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789312, Length=394, Percent_Identity=25.1269035532995, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786229, Length=423, Percent_Identity=25.531914893617, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789207, Length=379, Percent_Identity=24.5382585751979, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565976, Length=312, Percent_Identity=25.6410256410256, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321886, Length=393, Percent_Identity=23.4096692111959, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320552, Length=390, Percent_Identity=24.8717948717949, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321888, Length=389, Percent_Identity=23.3933161953728, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320549, Length=392, Percent_Identity=26.530612244898, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320550, Length=392, Percent_Identity=26.530612244898, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321884, Length=393, Percent_Identity=24.9363867684478, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24640198, Length=498, Percent_Identity=23.8955823293173, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640196, Length=498, Percent_Identity=23.8955823293173, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640200, Length=498, Percent_Identity=23.8955823293173, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28573097, Length=180, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24644448, Length=421, Percent_Identity=26.3657957244656, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24644446, Length=421, Percent_Identity=26.3657957244656, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 46739; Mature: 46739

Theoretical pI: Translated: 11.45; Mature: 11.45

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDARIQAARLSDPLAPVDGSVAAVTRRLDSLPITRLHAAALAVCTLGLFTDIAEVALSN
CCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAAIFLAPPHSMPRGSLSLLLASVFAGGAVGAPVFGMLGDRLGRGRALQASLALMAAGS
HHHHEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
LAAAASQGLTALTIARTVSGFAIGGFPPLVATYLAEVTPARHRGATLLVCAGLGLLGGLA
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHCCCEEEHHHHHHHHHHHH
AIGLVQMLAPGAPLGIEPWRWALILGGALAALGGLLFARLPESPRWLASVGRSAEADAAC
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHH
RRFERAAGRVRVAAPAGPDPAPAAAGPAGFRGLFAGPRQLRRTALFVGLYTLAPLATIAF
HHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
PLLSAVVMVEKGFKVDQSLVFAALSMLGPPLGTLLTALVIDRLERRACLTALAAAMAALG
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAFAASGTFLTLVLVGIAFNTAAATYGSILAVYATELLPTPLRASAMTCAWAGGRVAAAL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHH
APIILLPVLSAYGPHAMFAVITVVLAASAALLLSGPRGLSGRAVA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MVDARIQAARLSDPLAPVDGSVAAVTRRLDSLPITRLHAAALAVCTLGLFTDIAEVALSN
CCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAAIFLAPPHSMPRGSLSLLLASVFAGGAVGAPVFGMLGDRLGRGRALQASLALMAAGS
HHHHEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
LAAAASQGLTALTIARTVSGFAIGGFPPLVATYLAEVTPARHRGATLLVCAGLGLLGGLA
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHCCCEEEHHHHHHHHHHHH
AIGLVQMLAPGAPLGIEPWRWALILGGALAALGGLLFARLPESPRWLASVGRSAEADAAC
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHH
RRFERAAGRVRVAAPAGPDPAPAAAGPAGFRGLFAGPRQLRRTALFVGLYTLAPLATIAF
HHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
PLLSAVVMVEKGFKVDQSLVFAALSMLGPPLGTLLTALVIDRLERRACLTALAAAMAALG
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAFAASGTFLTLVLVGIAFNTAAATYGSILAVYATELLPTPLRASAMTCAWAGGRVAAAL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHH
APIILLPVLSAYGPHAMFAVITVVLAASAALLLSGPRGLSGRAVA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]