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The map label for this gene is rutD [H]

Identifier: 170751261

GI number: 170751261

Start: 5211906

End: 5212745

Strand: Reverse

Name: rutD [H]

Synonym: Mrad2831_4878

Alternate gene names: 170751261

Gene position: 5212745-5211906 (Counterclockwise)

Preceding gene: 170751262

Following gene: 170751259

Centisome position: 85.77

GC content: 71.07

Gene sequence:

>840_bases
ATGCTTCGGATTGTGATCGTCCTGACACTTCTGCTGGCCGGCGCACCGGCCTGGGCCGGGGCGCGCTGGCAGGACTTGCC
GCCGACCCCCGCGCCGGTCGCCGGCACGACCCCGGGCCGGGCCGCCATCAACGGCATCCGGCTGTATTACGCCACGATCG
GCAGCGGTCCGCCGGTCGTCCTGCTGCACGGCGGCCTGTCGAACTCCGATTACTGGGGCCATCAGGTCGCCGCGCTCGCC
GCCCGCCGCACGGTCATCCTCGTGGACAGCCGCGGGCACGGCCGCAGCACCCGGGACGATCGGCCGTTCGGCTACGACCT
CATGACCGACGACGTGGTCGGCCTGCTCGACGTGCTGAAGATCCCGCGCGCCGACATCGTCGGGTGGAGCGACGGCGCGA
TCCTCGGTCTCGACATGGCGATGCGCCACCCCGACCGCGTCGGCAAGGTGTTCGCGTTCGGCGCCAACGCCGATCCGTCG
GGCCTGATCGAGGGTGTGGAGAAGAACCCGACCTTCGCCGCCTTCATCGACCGGGCCGGCAAGGAGTACGAGGCCCTCTC
GCCGACCCCGAAGGACTACGCCGCCTTCGTCGACGCCGTGGGCCGGATGTGGAGCGGGCAGCCGCGCTGGACCGAAGCCG
ATCTGAAGCGGATCCGCGCGCCGGTCCTCATCGCGGACGGCGACCACGACGAGGGGATCAAGCGCGCGCACACCGAGTAC
CTCGCCGCCACGATCCCCGGGGCGGGCCTGCTGATCCTGCCGAACGCCAGCCACTTCGCGTTCCTGCAGGATCCGGCGCT
CTTCAATGCAGCGCTTCTCGCCTTCCTGGACGGGCCGTGA

Upstream 100 bases:

>100_bases
ACGGTCCGCGCGCATATCGACCGCGGATCGCGGTCGCGGCGGGTCGAGGAGGACCGGATCGCTCCAGCAGCCGGTCCCGC
CCATGACGGACAGGCGCTCG

Downstream 100 bases:

>100_bases
CCGCCGTGGACAGCCGCTCACGCGCGTGACGTCCGCCGCGCGCGCAACACGGCGACAGCCACGCACGGGCAGATACCCCG
CCCCACAACCTGGATGGCCC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Aminohydrolase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MLRIVIVLTLLLAGAPAWAGARWQDLPPTPAPVAGTTPGRAAINGIRLYYATIGSGPPVVLLHGGLSNSDYWGHQVAALA
ARRTVILVDSRGHGRSTRDDRPFGYDLMTDDVVGLLDVLKIPRADIVGWSDGAILGLDMAMRHPDRVGKVFAFGANADPS
GLIEGVEKNPTFAAFIDRAGKEYEALSPTPKDYAAFVDAVGRMWSGQPRWTEADLKRIRAPVLIADGDHDEGIKRAHTEY
LAATIPGAGLLILPNASHFAFLQDPALFNAALLAFLDGP

Sequences:

>Translated_279_residues
MLRIVIVLTLLLAGAPAWAGARWQDLPPTPAPVAGTTPGRAAINGIRLYYATIGSGPPVVLLHGGLSNSDYWGHQVAALA
ARRTVILVDSRGHGRSTRDDRPFGYDLMTDDVVGLLDVLKIPRADIVGWSDGAILGLDMAMRHPDRVGKVFAFGANADPS
GLIEGVEKNPTFAAFIDRAGKEYEALSPTPKDYAAFVDAVGRMWSGQPRWTEADLKRIRAPVLIADGDHDEGIKRAHTEY
LAATIPGAGLLILPNASHFAFLQDPALFNAALLAFLDGP
>Mature_279_residues
MLRIVIVLTLLLAGAPAWAGARWQDLPPTPAPVAGTTPGRAAINGIRLYYATIGSGPPVVLLHGGLSNSDYWGHQVAALA
ARRTVILVDSRGHGRSTRDDRPFGYDLMTDDVVGLLDVLKIPRADIVGWSDGAILGLDMAMRHPDRVGKVFAFGANADPS
GLIEGVEKNPTFAAFIDRAGKEYEALSPTPKDYAAFVDAVGRMWSGQPRWTEADLKRIRAPVLIADGDHDEGIKRAHTEY
LAATIPGAGLLILPNASHFAFLQDPALFNAALLAFLDGP

Specific function: May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Hydrolase RutD family [H]

Homologues:

Organism=Homo sapiens, GI221316588, Length=267, Percent_Identity=31.0861423220974, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24649021, Length=254, Percent_Identity=25.9842519685039, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR019913 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 29803; Mature: 29803

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRIVIVLTLLLAGAPAWAGARWQDLPPTPAPVAGTTPGRAAINGIRLYYATIGSGPPVV
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCEEEEEEEEECCCCCEE
LLHGGLSNSDYWGHQVAALAARRTVILVDSRGHGRSTRDDRPFGYDLMTDDVVGLLDVLK
EEECCCCCCCCCHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IPRADIVGWSDGAILGLDMAMRHPDRVGKVFAFGANADPSGLIEGVEKNPTFAAFIDRAG
CCCHHEECCCCCCEEEHHHHHCCCHHHCEEEEECCCCCHHHHHHCCCCCCCCEEHHHHCC
KEYEALSPTPKDYAAFVDAVGRMWSGQPRWTEADLKRIRAPVLIADGDHDEGIKRAHTEY
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCCHHHHHHHHHH
LAATIPGAGLLILPNASHFAFLQDPALFNAALLAFLDGP
HHEECCCCCEEEEECCCCEEEECCCHHHHHHHHHEECCC
>Mature Secondary Structure
MLRIVIVLTLLLAGAPAWAGARWQDLPPTPAPVAGTTPGRAAINGIRLYYATIGSGPPVV
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCEEEEEEEEECCCCCEE
LLHGGLSNSDYWGHQVAALAARRTVILVDSRGHGRSTRDDRPFGYDLMTDDVVGLLDVLK
EEECCCCCCCCCHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IPRADIVGWSDGAILGLDMAMRHPDRVGKVFAFGANADPSGLIEGVEKNPTFAAFIDRAG
CCCHHEECCCCCCEEEHHHHHCCCHHHCEEEEECCCCCHHHHHHCCCCCCCCEEHHHHCC
KEYEALSPTPKDYAAFVDAVGRMWSGQPRWTEADLKRIRAPVLIADGDHDEGIKRAHTEY
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCCHHHHHHHHHH
LAATIPGAGLLILPNASHFAFLQDPALFNAALLAFLDGP
HHEECCCCCEEEEECCCCEEEECCCHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA