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The map label for this gene is grp [H]

Identifier: 170748728

GI number: 170748728

Start: 2447100

End: 2447561

Strand: Reverse

Name: grp [H]

Synonym: Mrad2831_2310

Alternate gene names: 170748728

Gene position: 2447561-2447100 (Counterclockwise)

Preceding gene: 170748729

Following gene: 170748720

Centisome position: 40.27

GC content: 68.4

Gene sequence:

>462_bases
ATGGACGCCGTCGACCGGAAGATCCTCGATCTCCTCCAGCAGGACGCGACGCTCCCGGTGGCCGAGCTCGCCGAGCAGGT
CGGCATCAGCGCGGCGCCGTGCTGGCGGCGGGTGAAGAAGCTGGAGGCGTCCGGAGTGATCCGTCGCCGGGTCGCCCTGG
TGGATCGCCGCAAGGTCAACGTCCCCACCACGGTGTTCGTGGCCGTGAAGGCGCCGCGCCACGCCGCAGACTGGTCGGAC
GCCTTCCGGCGGGTGGTCGCCGGCTTCCCGGAGATCGTCGAGGCGTGGCGCCTGACCGGCGAGATCGACTACCTGCTGCG
GATCGTCGTGCCCGACATCGAGGCCTACGACGCGGTCTACCAGCGCCTCATCGCCAAGCTCGACTTCTCGAATCTGTCCT
CCTCCATCGCCATGGAGGAGATGAAGTACACGACCGCCGTCCCGACGATCTACGTGGCGTGA

Upstream 100 bases:

>100_bases
GGGCCGGGGCCGGCTCGAACTACCAGGCCCAGGGGCTCAAGCTCTCGAAGCATTTCGCCCTGTAGTCCGGCCCGGACCCG
CAGACGGGAGCAGCGATCGC

Downstream 100 bases:

>100_bases
GGCGACCGCGCTGCGGCGGGGCTCAGCCCGCCGCCACCGCGTAGGTCCGGTGGATCGACGAGTCCTGCGCCCGGTGGTCG
TAGCCGTAGACGTGGATCGA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MDAVDRKILDLLQQDATLPVAELAEQVGISAAPCWRRVKKLEASGVIRRRVALVDRRKVNVPTTVFVAVKAPRHAADWSD
AFRRVVAGFPEIVEAWRLTGEIDYLLRIVVPDIEAYDAVYQRLIAKLDFSNLSSSIAMEEMKYTTAVPTIYVA

Sequences:

>Translated_153_residues
MDAVDRKILDLLQQDATLPVAELAEQVGISAAPCWRRVKKLEASGVIRRRVALVDRRKVNVPTTVFVAVKAPRHAADWSD
AFRRVVAGFPEIVEAWRLTGEIDYLLRIVVPDIEAYDAVYQRLIAKLDFSNLSSSIAMEEMKYTTAVPTIYVA
>Mature_153_residues
MDAVDRKILDLLQQDATLPVAELAEQVGISAAPCWRRVKKLEASGVIRRRVALVDRRKVNVPTTVFVAVKAPRHAADWSD
AFRRVVAGFPEIVEAWRLTGEIDYLLRIVVPDIEAYDAVYQRLIAKLDFSNLSSSIAMEEMKYTTAVPTIYVA

Specific function: Represses the secondary, H(+)-coupled glutamate uptake system (Gluemp) genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=149, Percent_Identity=44.2953020134228, Blast_Score=148, Evalue=2e-37,
Organism=Escherichia coli, GI1787116, Length=146, Percent_Identity=34.2465753424658, Blast_Score=92, Evalue=1e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 17171; Mature: 17171

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAVDRKILDLLQQDATLPVAELAEQVGISAAPCWRRVKKLEASGVIRRRVALVDRRKVN
CCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPTTVFVAVKAPRHAADWSDAFRRVVAGFPEIVEAWRLTGEIDYLLRIVVPDIEAYDAVY
CCEEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHH
QRLIAKLDFSNLSSSIAMEEMKYTTAVPTIYVA
HHHHHHHCHHHHHHHHHHHHHHHHHHCCEEEEC
>Mature Secondary Structure
MDAVDRKILDLLQQDATLPVAELAEQVGISAAPCWRRVKKLEASGVIRRRVALVDRRKVN
CCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPTTVFVAVKAPRHAADWSDAFRRVVAGFPEIVEAWRLTGEIDYLLRIVVPDIEAYDAVY
CCEEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHH
QRLIAKLDFSNLSSSIAMEEMKYTTAVPTIYVA
HHHHHHHCHHHHHHHHHHHHHHHHHHCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665494 [H]