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The map label for this gene is surE

Identifier: 170748699

GI number: 170748699

Start: 2411750

End: 2412514

Strand: Reverse

Name: surE

Synonym: Mrad2831_2281

Alternate gene names: 170748699

Gene position: 2412514-2411750 (Counterclockwise)

Preceding gene: 170748700

Following gene: 170748698

Centisome position: 39.69

GC content: 70.98

Gene sequence:

>765_bases
ATGCGCATCCTGGTCACCAACGACGACGGCATCCACGCGCCGGGCCTCGCGACCCTGGAGGAGATCGCCCGGGAGCTCTC
GGACGACGTCTGGGTCGTGGCGCCGGAGAGCGACCAGTCCGGCGTGTCGCACTCGCTCTCGCTCAACGACCCGCTGCGGC
TGCGGCAGGTGTCGGAGCAGCGCTTCGCCGTGAAGGGCACGCCGTCGGACTGCGTGATCCTGGGCGTGCGCCACATCCTC
GGCGATCACGGGCCGGACCTCGTCCTGTCGGGGGTCAACCGCGGCCAGAACGTCGCCGAGGACGTGACCTATTCGGGCAC
GATCGCGGCCGCCATGGAGGGGACGATCCTCGGCATCCGCTCGATCGCGCTGAGCCAGGCCTACGGGGCGGGCGGGCGCG
GCGCCCTCAAGTGGGACTGCGCCCGGACGCACGGCGCGAAGGTCGTCCGGAAGATCCTCGAGACCGGGATCGAGCCCGGC
ATCCTGGTCAACGTCAATTTCCCGGATTGCGAGCCGGCCGACGTGCAGGGCGTCGCGGTCGCCGCGCAGGGCTTCCGCAA
TCAGGCGCTGCTGTCGATCGACGCGCGGGTCGACGGGCGCGGCAACCCGTATTTCTGGCTGGCCTTCGCCAAGGCCCGGT
TCGAGCCGGGCCACGGCTCCGATCTCAAGGCCATCGCCGAGAAGCGGATCTCGGTGACGCCCCTGCGCCTCGACCTCACC
GACGAGCCGACGCTGACGCGCTTCGCGCAGGCCTTCGCCGAGTGA

Upstream 100 bases:

>100_bases
CCGTGATGGAGAACTACCAGAACCCGGACGGGAGCATCACGGTCCCGTCGGTGCTCCACCCCTACATGGGCGGGCTCAAC
CGGATCGAAGGGGCCCGCTG

Downstream 100 bases:

>100_bases
TCGATCTGGGCAGCCTGGAGGAGGCTGCCGGCAACGCGGCCTTCGTGATGGCGCTCCGCGGCCGTGGCCTGCGGGACACC
GCGGTGCTGCGGGCCATGGA

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRILVTNDDGIHAPGLATLEEIARELSDDVWVVAPESDQSGVSHSLSLNDPLRLRQVSEQRFAVKGTPSDCVILGVRHIL
GDHGPDLVLSGVNRGQNVAEDVTYSGTIAAAMEGTILGIRSIALSQAYGAGGRGALKWDCARTHGAKVVRKILETGIEPG
ILVNVNFPDCEPADVQGVAVAAQGFRNQALLSIDARVDGRGNPYFWLAFAKARFEPGHGSDLKAIAEKRISVTPLRLDLT
DEPTLTRFAQAFAE

Sequences:

>Translated_254_residues
MRILVTNDDGIHAPGLATLEEIARELSDDVWVVAPESDQSGVSHSLSLNDPLRLRQVSEQRFAVKGTPSDCVILGVRHIL
GDHGPDLVLSGVNRGQNVAEDVTYSGTIAAAMEGTILGIRSIALSQAYGAGGRGALKWDCARTHGAKVVRKILETGIEPG
ILVNVNFPDCEPADVQGVAVAAQGFRNQALLSIDARVDGRGNPYFWLAFAKARFEPGHGSDLKAIAEKRISVTPLRLDLT
DEPTLTRFAQAFAE
>Mature_254_residues
MRILVTNDDGIHAPGLATLEEIARELSDDVWVVAPESDQSGVSHSLSLNDPLRLRQVSEQRFAVKGTPSDCVILGVRHIL
GDHGPDLVLSGVNRGQNVAEDVTYSGTIAAAMEGTILGIRSIALSQAYGAGGRGALKWDCARTHGAKVVRKILETGIEPG
ILVNVNFPDCEPADVQGVAVAAQGFRNQALLSIDARVDGRGNPYFWLAFAKARFEPGHGSDLKAIAEKRISVTPLRLDLT
DEPTLTRFAQAFAE

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=241, Percent_Identity=40.2489626556017, Blast_Score=165, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_METRJ (B1LXR9)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001754959.1
- ProteinModelPortal:   B1LXR9
- SMR:   B1LXR9
- GeneID:   6138313
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_2281
- HOGENOM:   HBG600532
- OMA:   VLININF
- ProtClustDB:   PRK00346
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 27172; Mature: 27172

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVTNDDGIHAPGLATLEEIARELSDDVWVVAPESDQSGVSHSLSLNDPLRLRQVSEQ
CEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCCHHHHHHHHH
RFAVKGTPSDCVILGVRHILGDHGPDLVLSGVNRGQNVAEDVTYSGTIAAAMEGTILGIR
HEEEECCCCCEEEEEHHHHHCCCCCCEEEECCCCCCCHHHHCCCCCEEEEHHCCCHHHHH
SIALSQAYGAGGRGALKWDCARTHGAKVVRKILETGIEPGILVNVNFPDCEPADVQGVAV
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEE
AAQGFRNQALLSIDARVDGRGNPYFWLAFAKARFEPGHGSDLKAIAEKRISVTPLRLDLT
EECCCCCCEEEEEEEEECCCCCCEEEEEEEEEECCCCCCCCHHHHHHCCCEECEEEEECC
DEPTLTRFAQAFAE
CCCHHHHHHHHHCC
>Mature Secondary Structure
MRILVTNDDGIHAPGLATLEEIARELSDDVWVVAPESDQSGVSHSLSLNDPLRLRQVSEQ
CEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCCHHHHHHHHH
RFAVKGTPSDCVILGVRHILGDHGPDLVLSGVNRGQNVAEDVTYSGTIAAAMEGTILGIR
HEEEECCCCCEEEEEHHHHHCCCCCCEEEECCCCCCCHHHHCCCCCEEEEHHCCCHHHHH
SIALSQAYGAGGRGALKWDCARTHGAKVVRKILETGIEPGILVNVNFPDCEPADVQGVAV
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEE
AAQGFRNQALLSIDARVDGRGNPYFWLAFAKARFEPGHGSDLKAIAEKRISVTPLRLDLT
EECCCCCCEEEEEEEEECCCCCCEEEEEEEEEECCCCCCCCHHHHHHCCCEECEEEEECC
DEPTLTRFAQAFAE
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA