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The map label for this gene is msrB1 [H]

Identifier: 170748549

GI number: 170748549

Start: 2271951

End: 2272361

Strand: Reverse

Name: msrB1 [H]

Synonym: Mrad2831_2131

Alternate gene names: 170748549

Gene position: 2272361-2271951 (Counterclockwise)

Preceding gene: 170748550

Following gene: 170748548

Centisome position: 37.39

GC content: 72.51

Gene sequence:

>411_bases
ATGGCCGACACGCCGACCACCAGCCCGGAGACCCGCAGCGACGCCGAGTGGCGCTCGGCGCTGACGCCGGAGCAGTACCG
GGTCCTGCGCGAGCACGGCACCGAGCGGGCCGGAACGAGCTGCCTGCTCGCCGAGAAGCGGGCCGGGACCTTCACCTGCG
CCGGCTGCGGGCAGCCGCTGTTCGAGCAGGGCACCAAGTTCGAGTCCGGGACCGGCTGGCCGAGCTTCTTCGAGCCGATC
GACGGCGCCGTCGGGACGACGGTGGACCGCAGCCACTGGATGGTCCGCACCGAGGTGCACTGCGCCCGCTGCCAGGGCCA
CCTCGGCCACGTCTTCGACGACGGCCCGGCGCCGACCGGCCTGCGCTACTGCATGAACGGCGCGGCGATGAATTTCGAGC
CGGCTGAATGA

Upstream 100 bases:

>100_bases
GAACGCGGCGTCTCCGGTCCCCGGGACGCCTGCGGCATCCTCCGGGACTGCCGGAGACGGCGCGCGTTCCCTATATAGCG
TGGCGAAAAGGGAGATCGCC

Downstream 100 bases:

>100_bases
GTCGCGCGTCCCGCTAACCTGGGTTCGGAAACCGGGCGCGAAAGCCGGGATATCGGGGACAGGCAGCGCCGTGGCCGGAT
CCTCGACCCGATCCGGTCTT

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase 1 [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MADTPTTSPETRSDAEWRSALTPEQYRVLREHGTERAGTSCLLAEKRAGTFTCAGCGQPLFEQGTKFESGTGWPSFFEPI
DGAVGTTVDRSHWMVRTEVHCARCQGHLGHVFDDGPAPTGLRYCMNGAAMNFEPAE

Sequences:

>Translated_136_residues
MADTPTTSPETRSDAEWRSALTPEQYRVLREHGTERAGTSCLLAEKRAGTFTCAGCGQPLFEQGTKFESGTGWPSFFEPI
DGAVGTTVDRSHWMVRTEVHCARCQGHLGHVFDDGPAPTGLRYCMNGAAMNFEPAE
>Mature_135_residues
ADTPTTSPETRSDAEWRSALTPEQYRVLREHGTERAGTSCLLAEKRAGTFTCAGCGQPLFEQGTKFESGTGWPSFFEPID
GAVGTTVDRSHWMVRTEVHCARCQGHLGHVFDDGPAPTGLRYCMNGAAMNFEPAE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=125, Percent_Identity=50.4, Blast_Score=127, Evalue=3e-30,
Organism=Homo sapiens, GI301336162, Length=125, Percent_Identity=50.4, Blast_Score=127, Evalue=3e-30,
Organism=Homo sapiens, GI73089054, Length=125, Percent_Identity=50.4, Blast_Score=127, Evalue=3e-30,
Organism=Homo sapiens, GI37620216, Length=125, Percent_Identity=50.4, Blast_Score=127, Evalue=3e-30,
Organism=Homo sapiens, GI117606353, Length=131, Percent_Identity=45.0381679389313, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788077, Length=137, Percent_Identity=43.7956204379562, Blast_Score=120, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17553450, Length=132, Percent_Identity=45.4545454545455, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI115532676, Length=132, Percent_Identity=45.4545454545455, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319816, Length=128, Percent_Identity=39.84375, Blast_Score=104, Evalue=6e-24,
Organism=Drosophila melanogaster, GI221378662, Length=131, Percent_Identity=41.9847328244275, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI221378664, Length=124, Percent_Identity=47.5806451612903, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI45553335, Length=128, Percent_Identity=46.875, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21356369, Length=128, Percent_Identity=46.875, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24645799, Length=128, Percent_Identity=46.875, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24645801, Length=139, Percent_Identity=43.1654676258993, Blast_Score=112, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24645804, Length=139, Percent_Identity=43.1654676258993, Blast_Score=112, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 14842; Mature: 14710

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTPTTSPETRSDAEWRSALTPEQYRVLREHGTERAGTSCLLAEKRAGTFTCAGCGQPL
CCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCCHH
FEQGTKFESGTGWPSFFEPIDGAVGTTVDRSHWMVRTEVHCARCQGHLGHVFDDGPAPTG
HHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCEECCCCCCHH
LRYCMNGAAMNFEPAE
HHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ADTPTTSPETRSDAEWRSALTPEQYRVLREHGTERAGTSCLLAEKRAGTFTCAGCGQPL
CCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCCHH
FEQGTKFESGTGWPSFFEPIDGAVGTTVDRSHWMVRTEVHCARCQGHLGHVFDDGPAPTG
HHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCEECCCCCCHH
LRYCMNGAAMNFEPAE
HHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]