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The map label for this gene is aldH [H]

Identifier: 170748534

GI number: 170748534

Start: 2250884

End: 2252461

Strand: Reverse

Name: aldH [H]

Synonym: Mrad2831_2116

Alternate gene names: 170748534

Gene position: 2252461-2250884 (Counterclockwise)

Preceding gene: 170748535

Following gene: 170748533

Centisome position: 37.06

GC content: 76.55

Gene sequence:

>1578_bases
ATGACCCTGCGCGGCGAGAACCTGATCGGCGCCGAGGCGCGGCGCGGCACCGAGGCGGCCTTCCGGGCCGTGGAGGCGGC
CACCGGACGGGCCCTGGAGCCGGATTTCCCGGGCGCGGACCGGGGCGACCTCGACCGGGCCTGCGCGCTCGCCGAGGCCG
CGTTCGACACCTTCCGCGAGACCGATCCGGAGGCGCGGGCCGGCTTCCTGGAGGCGATCGCCGCGAACATCCTGGACATC
GGGGACGACCTCGTCACCCGCTGCATGGCCGAGACGGGGCTGCCCCGGCCGCGGATCGAGGGCGAGCGCGCCCGGACGGT
CGGCCAGCTGCGCCTGTTCGCCGGCGTCGTCCGCGAGGGCAGCTACGTCGAGGCGCGGATCGACCCGGCGCTGCCGGACC
GCAAGCCGCTGCCCCGGCCGGACCTGCGCCTGCGCCGGATCGCCGTCGGCCCGGTGGCGGTGTTCGGCGCCTCGAACTTC
CCGCTGGCCTTCTCGGTGGCGGGCGGCGACACCGCCTCGGCCCTGGCGGCGGGCTGCCCGGTGGTGGTCAAGGCCCATCC
CGCCCATCCCGGCACCTCGGAGCTCGTCGGCCGCGCCATCCAGAAGGCGGTGGCCGCCTGCGGCCTGCCGGAGGGGACCT
TCTCGCTGCTGTTCGATGCCGGCCAGTCGATCGGGCAGGGGCTGGTGGCCGATCCCCGGATCGCCGCCGTCGGCTTCACG
GGCTCGCGCCGGGGCGGCACCGCCCTGATGGCGATCGCGGCCGGCCGCCCGTCGCCGATCCCGGTCTACGCCGAGATGAG
CAGCATCAACCCGGTGCTGCTGTTCCCCGGCGCGCTCGCCGCGCGCGGCGCGGCGATCGGCAAGGCGTTCGCGGCCTCGC
TGACGCTGGGCGCCGGGCAGTTCTGCACCAATCCCGGCCTGATCCTGGCGCTGCCGGGCCCGGGCCTCGACGCCTTCCTG
GAGGCTGCCGGCGCGGCCCTGCGCGAGAGCCCGGCCGCGACCATGCTGACGCCCGGCATCCAGCGCGCCTACCGCGAGGC
CGTGGCGCGGGTGGCCGGCCACGCCGCCGTCACCCGCATCGCCGAGGGTGCGGAGGGCGGGGCGACCCAGGGCCGGGCCA
CCCTGTTCGCCGCGGACTCGGACGTGTTCCTGGCGGATCCCGAGCTGCAGGAGGAGATGTTCGGCGCCTCGGGGCTCGTG
GTGCGCTGCGCGGACTTCGCCGCGATGCGGGCGGTTCTGGAGCGCCTGGAGGGCCAGCTCACCGCCTCGCTGCACCTCGC
GCCGGAGGATCACGCGGCCGCGCGCGACCTGCTGCCGCTCCTGGAGCGCCGCGTCGGCCGGATCCTGGTGGACGGGTTCG
GGACCGGCGTCGAGGTGGCGCACGCCATGGTGCATGGCGGCCCCTATCCGGCGACCTCGGACGGGCGCACGACCTCGGTG
GGCAGTCTCGCGATCGACCGATTCCTGCGGCCGGTGAGCTATCAGGACGTTCCCGACGCGCTGCTGCCGGCCGCGCTCCA
GGCCGCCAACCCGCTGGGCCTGCCCCGCCGGATCGACGGCACGCCCGAGCGCCGCTGA

Upstream 100 bases:

>100_bases
GCTATCCGCGAGAAGGCCCTGGCGGCGCAGCGGGGCTGACCGCCCGCACGCGCCGTCCCGGTGCGGCCCCGCCCGCACAC
CCTATCGAGAGGAGCAGCTC

Downstream 100 bases:

>100_bases
GCCGCGGCTGGCGGGCGCCGGACGGCCGCGATCCGCCGCTTGCCAGGGGCGGGCGCGGCGTCTAGACAGCCTCCGCTCAC
CTTGGGGCGTCGCCAAGTGG

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MTLRGENLIGAEARRGTEAAFRAVEAATGRALEPDFPGADRGDLDRACALAEAAFDTFRETDPEARAGFLEAIAANILDI
GDDLVTRCMAETGLPRPRIEGERARTVGQLRLFAGVVREGSYVEARIDPALPDRKPLPRPDLRLRRIAVGPVAVFGASNF
PLAFSVAGGDTASALAAGCPVVVKAHPAHPGTSELVGRAIQKAVAACGLPEGTFSLLFDAGQSIGQGLVADPRIAAVGFT
GSRRGGTALMAIAAGRPSPIPVYAEMSSINPVLLFPGALAARGAAIGKAFAASLTLGAGQFCTNPGLILALPGPGLDAFL
EAAGAALRESPAATMLTPGIQRAYREAVARVAGHAAVTRIAEGAEGGATQGRATLFAADSDVFLADPELQEEMFGASGLV
VRCADFAAMRAVLERLEGQLTASLHLAPEDHAAARDLLPLLERRVGRILVDGFGTGVEVAHAMVHGGPYPATSDGRTTSV
GSLAIDRFLRPVSYQDVPDALLPAALQAANPLGLPRRIDGTPERR

Sequences:

>Translated_525_residues
MTLRGENLIGAEARRGTEAAFRAVEAATGRALEPDFPGADRGDLDRACALAEAAFDTFRETDPEARAGFLEAIAANILDI
GDDLVTRCMAETGLPRPRIEGERARTVGQLRLFAGVVREGSYVEARIDPALPDRKPLPRPDLRLRRIAVGPVAVFGASNF
PLAFSVAGGDTASALAAGCPVVVKAHPAHPGTSELVGRAIQKAVAACGLPEGTFSLLFDAGQSIGQGLVADPRIAAVGFT
GSRRGGTALMAIAAGRPSPIPVYAEMSSINPVLLFPGALAARGAAIGKAFAASLTLGAGQFCTNPGLILALPGPGLDAFL
EAAGAALRESPAATMLTPGIQRAYREAVARVAGHAAVTRIAEGAEGGATQGRATLFAADSDVFLADPELQEEMFGASGLV
VRCADFAAMRAVLERLEGQLTASLHLAPEDHAAARDLLPLLERRVGRILVDGFGTGVEVAHAMVHGGPYPATSDGRTTSV
GSLAIDRFLRPVSYQDVPDALLPAALQAANPLGLPRRIDGTPERR
>Mature_524_residues
TLRGENLIGAEARRGTEAAFRAVEAATGRALEPDFPGADRGDLDRACALAEAAFDTFRETDPEARAGFLEAIAANILDIG
DDLVTRCMAETGLPRPRIEGERARTVGQLRLFAGVVREGSYVEARIDPALPDRKPLPRPDLRLRRIAVGPVAVFGASNFP
LAFSVAGGDTASALAAGCPVVVKAHPAHPGTSELVGRAIQKAVAACGLPEGTFSLLFDAGQSIGQGLVADPRIAAVGFTG
SRRGGTALMAIAAGRPSPIPVYAEMSSINPVLLFPGALAARGAAIGKAFAASLTLGAGQFCTNPGLILALPGPGLDAFLE
AAGAALRESPAATMLTPGIQRAYREAVARVAGHAAVTRIAEGAEGGATQGRATLFAADSDVFLADPELQEEMFGASGLVV
RCADFAAMRAVLERLEGQLTASLHLAPEDHAAARDLLPLLERRVGRILVDGFGTGVEVAHAMVHGGPYPATSDGRTTSVG
SLAIDRFLRPVSYQDVPDALLPAALQAANPLGLPRRIDGTPERR

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507229, Length=279, Percent_Identity=26.8817204301075, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1788042, Length=284, Percent_Identity=29.5774647887324, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787684, Length=268, Percent_Identity=27.2388059701493, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081896, Length=306, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786504, Length=295, Percent_Identity=27.7966101694915, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082295, Length=309, Percent_Identity=27.5080906148867, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1787250, Length=383, Percent_Identity=28.9817232375979, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6319478, Length=303, Percent_Identity=25.7425742574257, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 54265; Mature: 54133

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRGENLIGAEARRGTEAAFRAVEAATGRALEPDFPGADRGDLDRACALAEAAFDTFRE
CCCCCCCCCCCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
TDPEARAGFLEAIAANILDIGDDLVTRCMAETGLPRPRIEGERARTVGQLRLFAGVVREG
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCC
SYVEARIDPALPDRKPLPRPDLRLRRIAVGPVAVFGASNFPLAFSVAGGDTASALAAGCP
CEEEEEECCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCCEEEEECCCCHHHHHHCCCC
VVVKAHPAHPGTSELVGRAIQKAVAACGLPEGTFSLLFDAGQSIGQGLVADPRIAAVGFT
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECC
GSRRGGTALMAIAAGRPSPIPVYAEMSSINPVLLFPGALAARGAAIGKAFAASLTLGAGQ
CCCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
FCTNPGLILALPGPGLDAFLEAAGAALRESPAATMLTPGIQRAYREAVARVAGHAAVTRI
CCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHH
AEGAEGGATQGRATLFAADSDVFLADPELQEEMFGASGLVVRCADFAAMRAVLERLEGQL
HCCCCCCCCCCCEEEEEECCCEEEECCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCE
TASLHLAPEDHAAARDLLPLLERRVGRILVDGFGTGVEVAHAMVHGGPYPATSDGRTTSV
EEEEEECCCHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCH
GSLAIDRFLRPVSYQDVPDALLPAALQAANPLGLPRRIDGTPERR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLRGENLIGAEARRGTEAAFRAVEAATGRALEPDFPGADRGDLDRACALAEAAFDTFRE
CCCCCCCCCCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
TDPEARAGFLEAIAANILDIGDDLVTRCMAETGLPRPRIEGERARTVGQLRLFAGVVREG
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCC
SYVEARIDPALPDRKPLPRPDLRLRRIAVGPVAVFGASNFPLAFSVAGGDTASALAAGCP
CEEEEEECCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCCEEEEECCCCHHHHHHCCCC
VVVKAHPAHPGTSELVGRAIQKAVAACGLPEGTFSLLFDAGQSIGQGLVADPRIAAVGFT
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECC
GSRRGGTALMAIAAGRPSPIPVYAEMSSINPVLLFPGALAARGAAIGKAFAASLTLGAGQ
CCCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
FCTNPGLILALPGPGLDAFLEAAGAALRESPAATMLTPGIQRAYREAVARVAGHAAVTRI
CCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHH
AEGAEGGATQGRATLFAADSDVFLADPELQEEMFGASGLVVRCADFAAMRAVLERLEGQL
HCCCCCCCCCCCEEEEEECCCEEEECCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCE
TASLHLAPEDHAAARDLLPLLERRVGRILVDGFGTGVEVAHAMVHGGPYPATSDGRTTSV
EEEEEECCCHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCH
GSLAIDRFLRPVSYQDVPDALLPAALQAANPLGLPRRIDGTPERR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]