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The map label for this gene is xseA [H]

Identifier: 170747101

GI number: 170747101

Start: 713489

End: 715189

Strand: Reverse

Name: xseA [H]

Synonym: Mrad2831_0667

Alternate gene names: 170747101

Gene position: 715189-713489 (Counterclockwise)

Preceding gene: 170747102

Following gene: 170747099

Centisome position: 11.77

GC content: 76.31

Gene sequence:

>1701_bases
ATGCCCCTCGTGCCGCCCCCGCGCCCCGCAGCCCAGCCCGCGGCGGACATCCCGCCGACCAGCGTGCTCAACGCGAACCA
GCCGGAATGGTCGGTGGGCGAGCTCGCGGGCGCCCTGAAGCGCACCCTCGAGGACGCCTTCGGGCACGTCCGCCTGCGCG
GCGAGATCTCGGGGTATCGCGGCCAGCACGGCTCGGGCCACGCCTACTTCTCCCTGAAGGACGGGCAGGCGCGGATCGAC
GCGGTGGTCTGGAAGGGCGTGTTCGGACGACTTCGCCAGAGACCTCAGGAGGGTCTGGAGGTCGTCGCCACCGGCCGTAT
CACGACCTTCGCGGGCAAGTCCTCGTACCAGATCGTCATCGAGAGCCTGGAGCCTGCCGGGCTCGGCGCCTGGATGGCGC
TCCTGGAGGAGCGCAAGAAGCAGCTCGCCGCCGAGGGTCTCTTCGCGCCGGACCACAAGCGGCCGATCCCCTACCTGCCG
CGGGTGGTCGGCGTCGTCACCTCGCCGACCGGCGCGGTGATCCGCGACATCCTCCACCGGCTGGAGGACCGCTTCCCCCG
GCCGGTCCTGGTCTGGCCGGTGCGGGTTCAGGGCGACGGCGCGGCCGAGGAAGTCGCGGCCGCGATCCGCGGCTTCAACG
CCCTCCCGGCCGGGGGCCCGATCCCGCGCCCGGACGTGCTCATCGTGGCCCGCGGCGGCGGCTCCATCGAGGATCTCTGG
GCCTTCAACGAGGAGTGCGTCGTCCGCGCCGCCTTCGCGAGCGCGATCCCGCTGATCTCGGCGGTGGGGCACGAGACCGA
CACCACGCTGATCGACTACGTCTCGGATCGCCGCGCGCCGACCCCGACGGGCGCCGCCGAGATGGCGGTGCCGGTCCGCG
CCGACCTGATCGCCACGGTGGCGGACCTGGCGGCCCGCGGCAGGGGAGCGGTCGGGCGCCGGATCGACCGCGACCGCTCC
GACCTGCGCGCTCTCGGGCGCGCCTTGCCGAGCGCCGACGCCCTGCTGGCGGCCAAGCGCCAGCGGCTCGACCTCGCCGA
GGCGCGCCTCGCCCCGGCGCTGGCGGCGGGCGCGAGCCGCCACCGCGCGCGGCTCCAGCTCCTGCTCGACCGGATGGCCC
GGCGCTCGCCCGACGTGGCCCTCGCCAACGCACGCGCGCGGCTGGCGCGGATCGACCACCGGCCGCTCCACGCCCTGCGC
AACGATGTCCAGCGCAAGGGCGAGGCCCTGATCCAGCTCGGGCGACGCCTCGTCGTCGCGCGCGAGGCCAGCCTGGAACG
GGCCCGGGCGCTGCAGGCGCGCCGAACCGACCGGCTGCTCGCCCTGTCGGAGCGCCTCGCCCAGGCGGGTGCGCGCGGCA
TCGAGCGGCGCCGCGACCGGCTCGACGGTCTCGCGGGCCTGCTCGGCTCCCTGAGCTACCGCGCGGTGCTCGACCGGGGC
TACGTGCTGGTGCGCGACGCCGCGGGGCTCCCCGTCCGCCGCGCGGCGGCGGCGGCGGCGGCGCAGCGTCTCAGCCTGCA
ATTCGCCGACGGGACCGTGACGGCCGTGCCCGACGGGACGGACGATCCGTCCTTGCCGGTCGATCCGTCCCGGCCGGCGA
AGCCCGGACGTCGCGGCGGCGCGGCCGCACCGGCGGCGCCGGGCAAGCGGACCGGCACGCGCCCTGCCGCGACGCGGCAG
GGATCGCTGTTCGACGCCTGA

Upstream 100 bases:

>100_bases
GACGGCGCCGCTGTCGCGGCCAGCCCGGCTCGGGACGCGCACGAGCCCGTCTCCACAGCGGCCCTTTGACTGTCCCGCCG
GAGCCCCCTAGCGTCCGGCC

Downstream 100 bases:

>100_bases
GACGACGGCCGGGGCCGGATGAAGGAACTGGGCCGAGCCCCCCACCGCGTCTCAGCTAGGCTCCGGGCCGACCCGATAGT
GATAGCGGTACAACTCGTGC

Product: exodeoxyribonuclease VII, large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MPLVPPPRPAAQPAADIPPTSVLNANQPEWSVGELAGALKRTLEDAFGHVRLRGEISGYRGQHGSGHAYFSLKDGQARID
AVVWKGVFGRLRQRPQEGLEVVATGRITTFAGKSSYQIVIESLEPAGLGAWMALLEERKKQLAAEGLFAPDHKRPIPYLP
RVVGVVTSPTGAVIRDILHRLEDRFPRPVLVWPVRVQGDGAAEEVAAAIRGFNALPAGGPIPRPDVLIVARGGGSIEDLW
AFNEECVVRAAFASAIPLISAVGHETDTTLIDYVSDRRAPTPTGAAEMAVPVRADLIATVADLAARGRGAVGRRIDRDRS
DLRALGRALPSADALLAAKRQRLDLAEARLAPALAAGASRHRARLQLLLDRMARRSPDVALANARARLARIDHRPLHALR
NDVQRKGEALIQLGRRLVVAREASLERARALQARRTDRLLALSERLAQAGARGIERRRDRLDGLAGLLGSLSYRAVLDRG
YVLVRDAAGLPVRRAAAAAAAQRLSLQFADGTVTAVPDGTDDPSLPVDPSRPAKPGRRGGAAAPAAPGKRTGTRPAATRQ
GSLFDA

Sequences:

>Translated_566_residues
MPLVPPPRPAAQPAADIPPTSVLNANQPEWSVGELAGALKRTLEDAFGHVRLRGEISGYRGQHGSGHAYFSLKDGQARID
AVVWKGVFGRLRQRPQEGLEVVATGRITTFAGKSSYQIVIESLEPAGLGAWMALLEERKKQLAAEGLFAPDHKRPIPYLP
RVVGVVTSPTGAVIRDILHRLEDRFPRPVLVWPVRVQGDGAAEEVAAAIRGFNALPAGGPIPRPDVLIVARGGGSIEDLW
AFNEECVVRAAFASAIPLISAVGHETDTTLIDYVSDRRAPTPTGAAEMAVPVRADLIATVADLAARGRGAVGRRIDRDRS
DLRALGRALPSADALLAAKRQRLDLAEARLAPALAAGASRHRARLQLLLDRMARRSPDVALANARARLARIDHRPLHALR
NDVQRKGEALIQLGRRLVVAREASLERARALQARRTDRLLALSERLAQAGARGIERRRDRLDGLAGLLGSLSYRAVLDRG
YVLVRDAAGLPVRRAAAAAAAQRLSLQFADGTVTAVPDGTDDPSLPVDPSRPAKPGRRGGAAAPAAPGKRTGTRPAATRQ
GSLFDA
>Mature_565_residues
PLVPPPRPAAQPAADIPPTSVLNANQPEWSVGELAGALKRTLEDAFGHVRLRGEISGYRGQHGSGHAYFSLKDGQARIDA
VVWKGVFGRLRQRPQEGLEVVATGRITTFAGKSSYQIVIESLEPAGLGAWMALLEERKKQLAAEGLFAPDHKRPIPYLPR
VVGVVTSPTGAVIRDILHRLEDRFPRPVLVWPVRVQGDGAAEEVAAAIRGFNALPAGGPIPRPDVLIVARGGGSIEDLWA
FNEECVVRAAFASAIPLISAVGHETDTTLIDYVSDRRAPTPTGAAEMAVPVRADLIATVADLAARGRGAVGRRIDRDRSD
LRALGRALPSADALLAAKRQRLDLAEARLAPALAAGASRHRARLQLLLDRMARRSPDVALANARARLARIDHRPLHALRN
DVQRKGEALIQLGRRLVVAREASLERARALQARRTDRLLALSERLAQAGARGIERRRDRLDGLAGLLGSLSYRAVLDRGY
VLVRDAAGLPVRRAAAAAAAQRLSLQFADGTVTAVPDGTDDPSLPVDPSRPAKPGRRGGAAAPAAPGKRTGTRPAATRQG
SLFDA

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=488, Percent_Identity=33.6065573770492, Blast_Score=233, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 60456; Mature: 60325

Theoretical pI: Translated: 11.52; Mature: 11.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVPPPRPAAQPAADIPPTSVLNANQPEWSVGELAGALKRTLEDAFGHVRLRGEISGYR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCC
GQHGSGHAYFSLKDGQARIDAVVWKGVFGRLRQRPQEGLEVVATGRITTFAGKSSYQIVI
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCHHHCCEEEECCCEEEECCCCCEEEEE
ESLEPAGLGAWMALLEERKKQLAAEGLFAPDHKRPIPYLPRVVGVVTSPTGAVIRDILHR
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
LEDRFPRPVLVWPVRVQGDGAAEEVAAAIRGFNALPAGGPIPRPDVLIVARGGGSIEDLW
HHHHCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHH
AFNEECVVRAAFASAIPLISAVGHETDTTLIDYVSDRRAPTPTGAAEMAVPVRADLIATV
HCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHEECCHHHHHHHHH
ADLAARGRGAVGRRIDRDRSDLRALGRALPSADALLAAKRQRLDLAEARLAPALAAGASR
HHHHHCCCCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
HRARLQLLLDRMARRSPDVALANARARLARIDHRPLHALRNDVQRKGEALIQLGRRLVVA
HHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
REASLERARALQARRTDRLLALSERLAQAGARGIERRRDRLDGLAGLLGSLSYRAVLDRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YVLVRDAAGLPVRRAAAAAAAQRLSLQFADGTVTAVPDGTDDPSLPVDPSRPAKPGRRGG
EEEEECCCCCCHHHHHHHHHHHHHEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
AAAPAAPGKRTGTRPAATRQGSLFDA
CCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLVPPPRPAAQPAADIPPTSVLNANQPEWSVGELAGALKRTLEDAFGHVRLRGEISGYR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCC
GQHGSGHAYFSLKDGQARIDAVVWKGVFGRLRQRPQEGLEVVATGRITTFAGKSSYQIVI
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCHHHCCEEEECCCEEEECCCCCEEEEE
ESLEPAGLGAWMALLEERKKQLAAEGLFAPDHKRPIPYLPRVVGVVTSPTGAVIRDILHR
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
LEDRFPRPVLVWPVRVQGDGAAEEVAAAIRGFNALPAGGPIPRPDVLIVARGGGSIEDLW
HHHHCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHH
AFNEECVVRAAFASAIPLISAVGHETDTTLIDYVSDRRAPTPTGAAEMAVPVRADLIATV
HCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHEECCHHHHHHHHH
ADLAARGRGAVGRRIDRDRSDLRALGRALPSADALLAAKRQRLDLAEARLAPALAAGASR
HHHHHCCCCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
HRARLQLLLDRMARRSPDVALANARARLARIDHRPLHALRNDVQRKGEALIQLGRRLVVA
HHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
REASLERARALQARRTDRLLALSERLAQAGARGIERRRDRLDGLAGLLGSLSYRAVLDRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YVLVRDAAGLPVRRAAAAAAAQRLSLQFADGTVTAVPDGTDDPSLPVDPSRPAKPGRRGG
EEEEECCCCCCHHHHHHHHHHHHHEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
AAAPAAPGKRTGTRPAATRQGSLFDA
CCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA