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The map label for this gene is yusP [H]

Identifier: 170747102

GI number: 170747102

Start: 715314

End: 716786

Strand: Reverse

Name: yusP [H]

Synonym: Mrad2831_0668

Alternate gene names: 170747102

Gene position: 716786-715314 (Counterclockwise)

Preceding gene: 170747103

Following gene: 170747101

Centisome position: 11.79

GC content: 72.03

Gene sequence:

>1473_bases
ATGCCCACGCCCTCAGAGACGCGCCGCCCGCTGGTCCTCGCCGCGGTGATGGCGGCGATGTTCATGATCGCCATCGAGGC
GACGATCGTCTCGACGGCGATGCCGCAGATCGCCGGCCAGCTCGGCGACCTCCACCTCTACGCCTGGGTGTTCGCCTCCT
TCCTGCTGACCCAGACGGCCACCACGGTGGTGTTCGGCAAGCTCTCGGACCTGTACGGGCGTCGGCCGGTGCTGCTGTTC
GGCATCGCGGTGTTCCTGGCGGGCTCACTCCTGTGCGGGCTCGCGTGGTCCATGCCCTCGCTGATCCTGTTCCGCCTCAT
CCAGGGCGTCGGCGCCGGGGCGATCCAGCCGGTGAGCCTGACCGTCGTCGGCGACCTGTACGCGGCGCGGGAACGCGGCC
GGGTCCAGGGCTATCTCGCCAGCGTCTGGGGCATCTCCTCGGTGGCCGGCCCGCTGGTCGGCGGCCTGATCATCGGTCAC
CTGAGCTGGCCCTGGATCTTCTGGATCAACCTGCCGGTCGGCGTGATCGCGGCCGGCCTGTTCCTGCGCTTCCTCCACGA
GGGCGTCGAGCGCCGCCCTCGCCAGATCGACGCGATCGGCGCGGCCCTGTTCACCGCCGCCATCGCGGCGCTGATGATCG
CGCTGACCGAGGCGGGCGAGTCGGCCGAGGCCGCCCTGTGGCCGGCGCTGGCCTTCGTGGTGGCCGCGCTCCTGTTCGTC
GTCCAGGAGCGGCGCGCGCCGGACCCGATGCTCGACATCCGCCTGTGGATGCAGCGCCCCATCGCCACCGCCAACACCGC
GACGCTCCTCTCCGGCATGACGGTGATCGGGCTCACGGCGTTCCTGCCGATGTACGTGCAGGGCGTGCTGCGGCAATCGC
CCCTGATCGCCGGCCTGACCCTGACCCTGATGGTGCTCGGCTGGCCGATCGGCGCCACTACGGCGGCGCGCAGCTTCGTC
CGGTTCGGCCTGCGCCCCATCCTGCTGGTCGGCGCGACGCTCCTGCCCCTCGGCGCGGTCGCCTTCGTCGCGCTCGGAAC
GGACACCTCCCCGGTGGTGGCGGCCTGCGGCTCGGTCGTGATGGGGCTCGGCATGGGCTTCCTGTCCACCGCCGCCATCG
TGATCATCCAGGACAGCGTCGCCTGGGCGCAGCGCGGGGCGGCGACGGCCTCGAACATCTTCTCGCGCAACCTCGGCTCG
ACGCTCGGCGCGACCGTCCTCGGGGCCGTGCTGAATTACCGGCTCGCCAATCCGTCGAGCGGCCCGGCGGTGAATTCCGA
TCAGCTCCGCCGCCTGCTCGACGATCCGGCAAGCCTCGGGGCCGGCGGGGAGGCGATCCGGGGCGGCCTGCAGCACGCGC
TGCACGGCACGTTCTGGACGGTGTTCGCCGTGGCGGTGCTGACCCTGCTCCTGTCGCTGCTGGTCCCGCCGGTGGCGATC
TCCGACCGGCCGCGCGAGCTCGCCGTGGAGTAG

Upstream 100 bases:

>100_bases
CGCCCCGGGTATGTGCGCTCGCGCACGGATCTCGCCGCGGAGGAGCCGGATGCCGTGTTCAACGCTAGGTAGGCAGGCGC
GGCGGGCCTAGACCGGCGCG

Downstream 100 bases:

>100_bases
GCGGCGGAACCTTCCGATAGGACAGACGGCGCCGCTGTCGCGGCCAGCCCGGCTCGGGACGCGCACGAGCCCGTCTCCAC
AGCGGCCCTTTGACTGTCCC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MPTPSETRRPLVLAAVMAAMFMIAIEATIVSTAMPQIAGQLGDLHLYAWVFASFLLTQTATTVVFGKLSDLYGRRPVLLF
GIAVFLAGSLLCGLAWSMPSLILFRLIQGVGAGAIQPVSLTVVGDLYAARERGRVQGYLASVWGISSVAGPLVGGLIIGH
LSWPWIFWINLPVGVIAAGLFLRFLHEGVERRPRQIDAIGAALFTAAIAALMIALTEAGESAEAALWPALAFVVAALLFV
VQERRAPDPMLDIRLWMQRPIATANTATLLSGMTVIGLTAFLPMYVQGVLRQSPLIAGLTLTLMVLGWPIGATTAARSFV
RFGLRPILLVGATLLPLGAVAFVALGTDTSPVVAACGSVVMGLGMGFLSTAAIVIIQDSVAWAQRGAATASNIFSRNLGS
TLGATVLGAVLNYRLANPSSGPAVNSDQLRRLLDDPASLGAGGEAIRGGLQHALHGTFWTVFAVAVLTLLLSLLVPPVAI
SDRPRELAVE

Sequences:

>Translated_490_residues
MPTPSETRRPLVLAAVMAAMFMIAIEATIVSTAMPQIAGQLGDLHLYAWVFASFLLTQTATTVVFGKLSDLYGRRPVLLF
GIAVFLAGSLLCGLAWSMPSLILFRLIQGVGAGAIQPVSLTVVGDLYAARERGRVQGYLASVWGISSVAGPLVGGLIIGH
LSWPWIFWINLPVGVIAAGLFLRFLHEGVERRPRQIDAIGAALFTAAIAALMIALTEAGESAEAALWPALAFVVAALLFV
VQERRAPDPMLDIRLWMQRPIATANTATLLSGMTVIGLTAFLPMYVQGVLRQSPLIAGLTLTLMVLGWPIGATTAARSFV
RFGLRPILLVGATLLPLGAVAFVALGTDTSPVVAACGSVVMGLGMGFLSTAAIVIIQDSVAWAQRGAATASNIFSRNLGS
TLGATVLGAVLNYRLANPSSGPAVNSDQLRRLLDDPASLGAGGEAIRGGLQHALHGTFWTVFAVAVLTLLLSLLVPPVAI
SDRPRELAVE
>Mature_489_residues
PTPSETRRPLVLAAVMAAMFMIAIEATIVSTAMPQIAGQLGDLHLYAWVFASFLLTQTATTVVFGKLSDLYGRRPVLLFG
IAVFLAGSLLCGLAWSMPSLILFRLIQGVGAGAIQPVSLTVVGDLYAARERGRVQGYLASVWGISSVAGPLVGGLIIGHL
SWPWIFWINLPVGVIAAGLFLRFLHEGVERRPRQIDAIGAALFTAAIAALMIALTEAGESAEAALWPALAFVVAALLFVV
QERRAPDPMLDIRLWMQRPIATANTATLLSGMTVIGLTAFLPMYVQGVLRQSPLIAGLTLTLMVLGWPIGATTAARSFVR
FGLRPILLVGATLLPLGAVAFVALGTDTSPVVAACGSVVMGLGMGFLSTAAIVIIQDSVAWAQRGAATASNIFSRNLGST
LGATVLGAVLNYRLANPSSGPAVNSDQLRRLLDDPASLGAGGEAIRGGLQHALHGTFWTVFAVAVLTLLLSLLVPPVAIS
DRPRELAVE

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1790195, Length=326, Percent_Identity=31.2883435582822, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI87081983, Length=304, Percent_Identity=30.5921052631579, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789042, Length=287, Percent_Identity=30.3135888501742, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788710, Length=294, Percent_Identity=26.8707482993197, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788392, Length=350, Percent_Identity=30.2857142857143, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1790146, Length=172, Percent_Identity=29.6511627906977, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI48994889, Length=116, Percent_Identity=35.3448275862069, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788509, Length=144, Percent_Identity=29.8611111111111, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322958, Length=547, Percent_Identity=24.6800731261426, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6323735, Length=470, Percent_Identity=25.1063829787234, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321663, Length=171, Percent_Identity=34.5029239766082, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6319770, Length=424, Percent_Identity=25.7075471698113, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319783, Length=426, Percent_Identity=24.4131455399061, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6325455, Length=529, Percent_Identity=20.6049149338374, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324264, Length=176, Percent_Identity=27.8409090909091, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51383; Mature: 51252

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTPSETRRPLVLAAVMAAMFMIAIEATIVSTAMPQIAGQLGDLHLYAWVFASFLLTQTA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TTVVFGKLSDLYGRRPVLLFGIAVFLAGSLLCGLAWSMPSLILFRLIQGVGAGAIQPVSL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
TVVGDLYAARERGRVQGYLASVWGISSVAGPLVGGLIIGHLSWPWIFWINLPVGVIAAGL
EEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHH
FLRFLHEGVERRPRQIDAIGAALFTAAIAALMIALTEAGESAEAALWPALAFVVAALLFV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VQERRAPDPMLDIRLWMQRPIATANTATLLSGMTVIGLTAFLPMYVQGVLRQSPLIAGLT
HHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LTLMVLGWPIGATTAARSFVRFGLRPILLVGATLLPLGAVAFVALGTDTSPVVAACGSVV
HHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
MGLGMGFLSTAAIVIIQDSVAWAQRGAATASNIFSRNLGSTLGATVLGAVLNYRLANPSS
HHHHHHHHHHHEEEEEECCHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
GPAVNSDQLRRLLDDPASLGAGGEAIRGGLQHALHGTFWTVFAVAVLTLLLSLLVPPVAI
CCCCCHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SDRPRELAVE
CCCCCCCCCC
>Mature Secondary Structure 
PTPSETRRPLVLAAVMAAMFMIAIEATIVSTAMPQIAGQLGDLHLYAWVFASFLLTQTA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TTVVFGKLSDLYGRRPVLLFGIAVFLAGSLLCGLAWSMPSLILFRLIQGVGAGAIQPVSL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
TVVGDLYAARERGRVQGYLASVWGISSVAGPLVGGLIIGHLSWPWIFWINLPVGVIAAGL
EEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHH
FLRFLHEGVERRPRQIDAIGAALFTAAIAALMIALTEAGESAEAALWPALAFVVAALLFV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VQERRAPDPMLDIRLWMQRPIATANTATLLSGMTVIGLTAFLPMYVQGVLRQSPLIAGLT
HHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LTLMVLGWPIGATTAARSFVRFGLRPILLVGATLLPLGAVAFVALGTDTSPVVAACGSVV
HHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
MGLGMGFLSTAAIVIIQDSVAWAQRGAATASNIFSRNLGSTLGATVLGAVLNYRLANPSS
HHHHHHHHHHHEEEEEECCHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
GPAVNSDQLRRLLDDPASLGAGGEAIRGGLQHALHGTFWTVFAVAVLTLLLSLLVPPVAI
CCCCCHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SDRPRELAVE
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]