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The map label for this gene is trxB [H]

Identifier: 170746997

GI number: 170746997

Start: 606388

End: 607368

Strand: Reverse

Name: trxB [H]

Synonym: Mrad2831_0563

Alternate gene names: 170746997

Gene position: 607368-606388 (Counterclockwise)

Preceding gene: 170746998

Following gene: 170746996

Centisome position: 9.99

GC content: 69.11

Gene sequence:

>981_bases
ATGGCCCACACCCACGCCAAGCTCGTGATCATCGGCTCGGGACCCGCCGGCTACACGGCGGCGATCTACGCGGCCCGCGC
CATGGTCGAGCCGCTGCTGATCTCCGGCTTCCAGCCGGGCGGCCAGCTCATGATCACCACGGACGTCGAGAATTACCCGG
GTTTCGCCGAGGCGATCCAGGGCCCGTGGCTGATGGAGCAGATGCGACTCCAGGCCGAGCATGTCGGCACTCGGATCGTC
TCGGAATACATCACGAAGGTCGACCTCAAGCAGCGGCCCTTCCGCCTCGAGGCCGATTCCGGCGAGACCTACTCGTGCGA
CGCCCTCGTCATCGCCACCGGCGCCCAGGCCAAGTGGCTCGGCATCCCCTCCGAGGCGGCTTTCCAGGGCGGCGGCGTCT
CGGCCTGCGCGACCTGCGACGGGTTCTTCTTCCGCGGCAAGGAGGTCGTGGTGGTCGGCGGCGGCAACACCGCGGTCGAG
GAGGCCCTGTACCTCGCCAACATCGCCAGCAAGGTCACGGTGGTCCATCGCCGCGACAGCTTCCGCGCCGAGCGGATCCT
GCAGGAGCGCCTGTTCAAGCACCCGAACGTCGAGGTGCTCTGGCACCGCGAGATCGCCGAGATCTGCGGAGTGCAGAAGC
CGGCGCCGAACGTGACCCACGTCCGTCTCAAGGATCCGCGCTCGGGCGAGATCAGCGAGGTGAAAGCCGACGGCGTGTTC
GTGGCGATCGGTCACCAGCCGGCCACCGCGATCTTCGAGGGGCAGCTGCCCATGCGCCACGGCGGCTACCTCACCGTGAA
GCCGGGGACGACCGAGACCGAGATCCCGGGCGTCTTCGCCGCGGGCGACGTCACGGACGACGTCTACCGCCAGGCGATCA
CCGCCGCCGGCATGGGCTGCATGGCGGCGCTGGAGGCGGAGAAGTTCCTGGCCAACCTCGACATCGGCGAGAGCCCCGTT
CAGGCCGCCGCGGCGGAATGA

Upstream 100 bases:

>100_bases
CGTACAAGCCGATCGACGCGACGCCGGTGATCGCCCAGGCGCTCGCCGACGCCTATGCCGCGCGCCGCGCGGCCGGACCG
GCCTGAGGAGACCGAGACAG

Downstream 100 bases:

>100_bases
CGGCCGCGGCGGCTCCGCGCCCCCCGCGCGGAGCCGCCGCGCCTAGCATTTCAACAAGTTCGCGCTGCTCGCGCTTGCGC
AGCACCATGCACCGTGTGCA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MAHTHAKLVIIGSGPAGYTAAIYAARAMVEPLLISGFQPGGQLMITTDVENYPGFAEAIQGPWLMEQMRLQAEHVGTRIV
SEYITKVDLKQRPFRLEADSGETYSCDALVIATGAQAKWLGIPSEAAFQGGGVSACATCDGFFFRGKEVVVVGGGNTAVE
EALYLANIASKVTVVHRRDSFRAERILQERLFKHPNVEVLWHREIAEICGVQKPAPNVTHVRLKDPRSGEISEVKADGVF
VAIGHQPATAIFEGQLPMRHGGYLTVKPGTTETEIPGVFAAGDVTDDVYRQAITAAGMGCMAALEAEKFLANLDIGESPV
QAAAAE

Sequences:

>Translated_326_residues
MAHTHAKLVIIGSGPAGYTAAIYAARAMVEPLLISGFQPGGQLMITTDVENYPGFAEAIQGPWLMEQMRLQAEHVGTRIV
SEYITKVDLKQRPFRLEADSGETYSCDALVIATGAQAKWLGIPSEAAFQGGGVSACATCDGFFFRGKEVVVVGGGNTAVE
EALYLANIASKVTVVHRRDSFRAERILQERLFKHPNVEVLWHREIAEICGVQKPAPNVTHVRLKDPRSGEISEVKADGVF
VAIGHQPATAIFEGQLPMRHGGYLTVKPGTTETEIPGVFAAGDVTDDVYRQAITAAGMGCMAALEAEKFLANLDIGESPV
QAAAAE
>Mature_325_residues
AHTHAKLVIIGSGPAGYTAAIYAARAMVEPLLISGFQPGGQLMITTDVENYPGFAEAIQGPWLMEQMRLQAEHVGTRIVS
EYITKVDLKQRPFRLEADSGETYSCDALVIATGAQAKWLGIPSEAAFQGGGVSACATCDGFFFRGKEVVVVGGGNTAVEE
ALYLANIASKVTVVHRRDSFRAERILQERLFKHPNVEVLWHREIAEICGVQKPAPNVTHVRLKDPRSGEISEVKADGVFV
AIGHQPATAIFEGQLPMRHGGYLTVKPGTTETEIPGVFAAGDVTDDVYRQAITAAGMGCMAALEAEKFLANLDIGESPVQ
AAAAE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=317, Percent_Identity=58.6750788643533, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI87081763, Length=293, Percent_Identity=31.740614334471, Blast_Score=146, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=46.0567823343849, Blast_Score=286, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=44.6875, Blast_Score=279, Evalue=4e-76,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34893; Mature: 34762

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHTHAKLVIIGSGPAGYTAAIYAARAMVEPLLISGFQPGGQLMITTDVENYPGFAEAIQ
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHC
GPWLMEQMRLQAEHVGTRIVSEYITKVDLKQRPFRLEADSGETYSCDALVIATGAQAKWL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCEEEEEECCCEEEE
GIPSEAAFQGGGVSACATCDGFFFRGKEVVVVGGGNTAVEEALYLANIASKVTVVHRRDS
CCCCHHHCCCCCCEEEEECCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCH
FRAERILQERLFKHPNVEVLWHREIAEICGVQKPAPNVTHVRLKDPRSGEISEVKADGVF
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEECCCEE
VAIGHQPATAIFEGQLPMRHGGYLTVKPGTTETEIPGVFAAGDVTDDVYRQAITAAGMGC
EEECCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCHH
MAALEAEKFLANLDIGESPVQAAAAE
HHHHHHHHHHHHCCCCCCCCHHCCCC
>Mature Secondary Structure 
AHTHAKLVIIGSGPAGYTAAIYAARAMVEPLLISGFQPGGQLMITTDVENYPGFAEAIQ
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHC
GPWLMEQMRLQAEHVGTRIVSEYITKVDLKQRPFRLEADSGETYSCDALVIATGAQAKWL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCEEEEEECCCEEEE
GIPSEAAFQGGGVSACATCDGFFFRGKEVVVVGGGNTAVEEALYLANIASKVTVVHRRDS
CCCCHHHCCCCCCEEEEECCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCH
FRAERILQERLFKHPNVEVLWHREIAEICGVQKPAPNVTHVRLKDPRSGEISEVKADGVF
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEECCCEE
VAIGHQPATAIFEGQLPMRHGGYLTVKPGTTETEIPGVFAAGDVTDDVYRQAITAAGMGC
EEECCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCHH
MAALEAEKFLANLDIGESPVQAAAAE
HHHHHHHHHHHHCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA