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The map label for this gene is tsr [C]

Identifier: 170746829

GI number: 170746829

Start: 426276

End: 427973

Strand: Reverse

Name: tsr [C]

Synonym: Mrad2831_0387

Alternate gene names: 170746829

Gene position: 427973-426276 (Counterclockwise)

Preceding gene: 170746830

Following gene: 170746828

Centisome position: 7.04

GC content: 70.61

Gene sequence:

>1698_bases
ATGGCGCGCCTTTCCGACCTCAAGATTGTTACCAAGGTGACGATCCCGCTGCTGCTGGTCGCCGCCGTCGCCGGCGGGCT
CGTGTATCGCGCGCACGGCGTCTTTGATGAGTTGAACGAGAAAACGCAGCACATCGTCGATGTCCAGTCCGCGCGACTTG
AGAATATCCTGACTGTTCGCACGAACGTCCTCGAGGCGACGGTTCAGAATCGGAACATCCTCATCGAGGACCGGCCTCCC
GAGCAGGCCATGTACCGATCGCGCTACGACGAGGCCGTGAAACAGGCCTACGTGGCGGTCGACAGGCTGATCGCGCTGTC
GAACTCGCCCGAGCGGCGGGCCGTCAATCAGAAGCTGCGCGAGGCCGTCGAGGTCTATTTCCACGTCGTCGGGCGCGCGA
ACGCGGCGGCCCTCGACAGGGACGCCGAAACCGCGCGGAAAATCGTGCTTTCCGAGGGTCTCGCGGCCCGCAACAAGGTC
CGCGATCTCGTCCAGCCGCGCATCGACAATCTCGCGGCCGAGCTCGCCCAGGCGAAGGCGAAGGCCCAGGCGAGCGCGGA
GCGGGCGACGACGGTCCTCGTCACGGCCGCGGTCGCCGGGCTGCTCGCGGCCCTGGCCATTGCGTTCGCCATCGTCCATT
TCGGGCTGACGCGGCCCCTGACCCGGTTGGTCGCCGTTCTGCAGCGCATGGCCAAGGGCGATCTCGACGCCGACATCGCG
GAGGCTGCCCGTCGCGACGAGATCGGCCAGGTCGGCAAGGCCGTCGCCGACATCCGCGCCATGGTCGCGCGGAAGGCCGT
CGAGGACGCGGAGACGAAGCGCGCCGCCGACGCGGCGCTCGGCGCCGAGCGACGGCGCATCATGATGGACCTCGCGAACG
GCTTCGAGCGGACGGTCGGCGGCATCGTCGGGATGGTCTCGGCCTCCGCGACGGAGTTGCAGGCCACGGCCGCGACGATG
ACGGCGACCGCCACCGAGACGGCCACGCAGTCCACGGCCGTGGCGGCGGCGGCCGATCAGGCAGCGTCGAACGTCGGAAC
CGTGGCGGCGGCCTCCGAGGAGCTCGGGAGCTCGGTTCAGGAGATCGGCCGTCAGGTACAGGGATCGGCATCCCTCGCCC
AGGCCGCTGTCGGCGAGGCCGACCGGACGGTCCGGCTCGTCGAGGACCTCACGACGGCCGTCGCGAGGATCGGTGACGTC
GTCGCGATGATCTCGGCCATCGCCGGCCAAACCAACCTCCTGGCGCTGAACGCGACCATCGAGGCGGCGCGGGCCGGCGA
GGCCGGCAAGGGCTTCGCGGTCGTCGCAGCCGAGGTCAAGGAACTCGCGTCGCAGACGGCCCGGGCGACGGACGAGATCG
GCGGCCATATCGGCCGCATCCAGGGCGTGACGGGCGAGGCGGTCTCGGCCATCGGCGCGATCACGGGGCGCATCCGCGAG
ATCAACACGGTGGCGGCCAGCATTGCCGCCGCCGTGGAGCAGCAGGGCGCGGCGACCCAGGAGATCGTGCGCAACGTCGC
CCAGGCGGCGACGGGCACCGCGGAGGTGACCGGCAACATCGCCGGAGTCGCCTCAGCGTCGGAGGCTACCGGCGCGGCGG
CGACCCAGGTGCTGGCGTCGTCCGGCGAGCTGTCGCGACACGCCGAGCAGCTCGCAGCGGAGATGACGCGCTTCCTCACC
ACCGTGCGCGCGGCCTGA

Upstream 100 bases:

>100_bases
CTCTCTCGTCGCGCTGAGGACGCCCCCGGCGCGCGCTTGCCGGGCAACGCGTCTTTAAATGCGGCGACTTCAAAATTCAG
AAGTAGCGGAGCAACAGTAC

Downstream 100 bases:

>100_bases
GGCGATCCCGATGGCGTGCAGCACAGCCAGCGTCCCGGGCCTCGGGTTCAATCCCACGCTTCGGCTGGGTTGCCGGGGAG
ATGCCCCGTCGGGGCACCGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MARLSDLKIVTKVTIPLLLVAAVAGGLVYRAHGVFDELNEKTQHIVDVQSARLENILTVRTNVLEATVQNRNILIEDRPP
EQAMYRSRYDEAVKQAYVAVDRLIALSNSPERRAVNQKLREAVEVYFHVVGRANAAALDRDAETARKIVLSEGLAARNKV
RDLVQPRIDNLAAELAQAKAKAQASAERATTVLVTAAVAGLLAALAIAFAIVHFGLTRPLTRLVAVLQRMAKGDLDADIA
EAARRDEIGQVGKAVADIRAMVARKAVEDAETKRAADAALGAERRRIMMDLANGFERTVGGIVGMVSASATELQATAATM
TATATETATQSTAVAAAADQAASNVGTVAAASEELGSSVQEIGRQVQGSASLAQAAVGEADRTVRLVEDLTTAVARIGDV
VAMISAIAGQTNLLALNATIEAARAGEAGKGFAVVAAEVKELASQTARATDEIGGHIGRIQGVTGEAVSAIGAITGRIRE
INTVAASIAAAVEQQGAATQEIVRNVAQAATGTAEVTGNIAGVASASEATGAAATQVLASSGELSRHAEQLAAEMTRFLT
TVRAA

Sequences:

>Translated_565_residues
MARLSDLKIVTKVTIPLLLVAAVAGGLVYRAHGVFDELNEKTQHIVDVQSARLENILTVRTNVLEATVQNRNILIEDRPP
EQAMYRSRYDEAVKQAYVAVDRLIALSNSPERRAVNQKLREAVEVYFHVVGRANAAALDRDAETARKIVLSEGLAARNKV
RDLVQPRIDNLAAELAQAKAKAQASAERATTVLVTAAVAGLLAALAIAFAIVHFGLTRPLTRLVAVLQRMAKGDLDADIA
EAARRDEIGQVGKAVADIRAMVARKAVEDAETKRAADAALGAERRRIMMDLANGFERTVGGIVGMVSASATELQATAATM
TATATETATQSTAVAAAADQAASNVGTVAAASEELGSSVQEIGRQVQGSASLAQAAVGEADRTVRLVEDLTTAVARIGDV
VAMISAIAGQTNLLALNATIEAARAGEAGKGFAVVAAEVKELASQTARATDEIGGHIGRIQGVTGEAVSAIGAITGRIRE
INTVAASIAAAVEQQGAATQEIVRNVAQAATGTAEVTGNIAGVASASEATGAAATQVLASSGELSRHAEQLAAEMTRFLT
TVRAA
>Mature_564_residues
ARLSDLKIVTKVTIPLLLVAAVAGGLVYRAHGVFDELNEKTQHIVDVQSARLENILTVRTNVLEATVQNRNILIEDRPPE
QAMYRSRYDEAVKQAYVAVDRLIALSNSPERRAVNQKLREAVEVYFHVVGRANAAALDRDAETARKIVLSEGLAARNKVR
DLVQPRIDNLAAELAQAKAKAQASAERATTVLVTAAVAGLLAALAIAFAIVHFGLTRPLTRLVAVLQRMAKGDLDADIAE
AARRDEIGQVGKAVADIRAMVARKAVEDAETKRAADAALGAERRRIMMDLANGFERTVGGIVGMVSASATELQATAATMT
ATATETATQSTAVAAAADQAASNVGTVAAASEELGSSVQEIGRQVQGSASLAQAAVGEADRTVRLVEDLTTAVARIGDVV
AMISAIAGQTNLLALNATIEAARAGEAGKGFAVVAAEVKELASQTARATDEIGGHIGRIQGVTGEAVSAIGAITGRIREI
NTVAASIAAAVEQQGAATQEIVRNVAQAATGTAEVTGNIAGVASASEATGAAATQVLASSGELSRHAEQLAAEMTRFLTT
VRAA

Specific function: May bind attractants or detect changes in the extracellular concentration of soluble sugars [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=346, Percent_Identity=30.0578034682081, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788194, Length=193, Percent_Identity=35.2331606217617, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787690, Length=335, Percent_Identity=27.7611940298507, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789453, Length=262, Percent_Identity=30.9160305343511, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788195, Length=235, Percent_Identity=32.7659574468085, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58559; Mature: 58428

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLSDLKIVTKVTIPLLLVAAVAGGLVYRAHGVFDELNEKTQHIVDVQSARLENILTVR
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNVLEATVQNRNILIEDRPPEQAMYRSRYDEAVKQAYVAVDRLIALSNSPERRAVNQKLR
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EAVEVYFHVVGRANAAALDRDAETARKIVLSEGLAARNKVRDLVQPRIDNLAAELAQAKA
HHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAQASAERATTVLVTAAVAGLLAALAIAFAIVHFGLTRPLTRLVAVLQRMAKGDLDADIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
EAARRDEIGQVGKAVADIRAMVARKAVEDAETKRAADAALGAERRRIMMDLANGFERTVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVGMVSASATELQATAATMTATATETATQSTAVAAAADQAASNVGTVAAASEELGSSVQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
EIGRQVQGSASLAQAAVGEADRTVRLVEDLTTAVARIGDVVAMISAIAGQTNLLALNATI
HHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHH
EAARAGEAGKGFAVVAAEVKELASQTARATDEIGGHIGRIQGVTGEAVSAIGAITGRIRE
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHH
INTVAASIAAAVEQQGAATQEIVRNVAQAATGTAEVTGNIAGVASASEATGAAATQVLAS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCHHCCCCCCHHHHHHHHHHHHC
SGELSRHAEQLAAEMTRFLTTVRAA
CCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARLSDLKIVTKVTIPLLLVAAVAGGLVYRAHGVFDELNEKTQHIVDVQSARLENILTVR
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNVLEATVQNRNILIEDRPPEQAMYRSRYDEAVKQAYVAVDRLIALSNSPERRAVNQKLR
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EAVEVYFHVVGRANAAALDRDAETARKIVLSEGLAARNKVRDLVQPRIDNLAAELAQAKA
HHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAQASAERATTVLVTAAVAGLLAALAIAFAIVHFGLTRPLTRLVAVLQRMAKGDLDADIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
EAARRDEIGQVGKAVADIRAMVARKAVEDAETKRAADAALGAERRRIMMDLANGFERTVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIVGMVSASATELQATAATMTATATETATQSTAVAAAADQAASNVGTVAAASEELGSSVQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
EIGRQVQGSASLAQAAVGEADRTVRLVEDLTTAVARIGDVVAMISAIAGQTNLLALNATI
HHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHH
EAARAGEAGKGFAVVAAEVKELASQTARATDEIGGHIGRIQGVTGEAVSAIGAITGRIRE
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHH
INTVAASIAAAVEQQGAATQEIVRNVAQAATGTAEVTGNIAGVASASEATGAAATQVLAS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCHHCCCCCCHHHHHHHHHHHHC
SGELSRHAEQLAAEMTRFLTTVRAA
CCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8436949 [H]