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The map label for this gene is yciR [C]

Identifier: 170746830

GI number: 170746830

Start: 428116

End: 430521

Strand: Reverse

Name: yciR [C]

Synonym: Mrad2831_0388

Alternate gene names: 170746830

Gene position: 430521-428116 (Counterclockwise)

Preceding gene: 170746836

Following gene: 170746829

Centisome position: 7.08

GC content: 71.4

Gene sequence:

>2406_bases
ATGAGTGAGATCATCCTGCCGATGGGCGTCGACGACGCGGCGCACCTGCCCGACGAGGACGCGCGCCTGCGTGAGGCGAT
GCGCGCCACGATGCTCGCCGAGACGCTGCAACTCGGCCGTTACTCGGCGGTGACGCAGGCCGCCGTCGTGCTCGCGCTGG
CCGCCATCTTTTGGGGCATCGTCTCGCACGCTTACCTGTCCGGTCTCGCGGTGGCGGTGACGGCGCTGTGCGCGGTGGCT
ATGATCGCGATGCGACGCTATCGCGGCCGCCTCGGCGACCGATCGATCGCCCGGGAGGCCTTCGCTGTCCTTCACGGCCT
CGCGCTCGGCCGCGGTCTCGCCTGGGCCAGCATGCCGGCGATCCTGCTGCCCTCGGTCGACAATGCCTACCGGATCGTGG
TCGGGGCCGTCTGCGCCGCCCTGATCTCGCACGCCTACGTGGCGGGCCCGATCTTCTCCCTGTCGCTCCTGGCCGTGGCG
CCGGTGGTGGCCGGCATCTTCGTCGGGCTCGCCGGTTGCGAGAGCCCGGTCGGCGAGTACGTCGCCGTGCTGCTGTCGCT
GTACGCGGCCTTCGTCTTCGTGAGCGCGCGTCGGATGTGCCGGCACTCCTACCAGCGTCTCTGCGACCGCGTCATGGTGC
AGGCGCAGAGCGAGACCATCGGGTTCCTCCTCAAGGATTTCGCCGAGGGCACGAGCGACTGGCTCTGGGAAACCGACACG
GTCGGGCGCCTTCGGCAGGCCCGCGCCGCTGTCGCCGCCCTACTCGGCGTCGAGGTCGCCGGGCTGCGCCACCGGACGTT
GTCCGAGCTCCTGCGCGCGTTCGCCGACCCGGACGGCGACGGCGCGGATGCCCAGGCCGTCGCCGCGGCGATCGCGGCGC
GCGCGCCTTTCCGCGATCGCACCATCCGGCTCCGTACCGCGGTCGGCACGCGCTGGATCACGCTCAACGGCAAGCCCGTC
TTCGACGCACAGGGAGCGTTCACGGGCTACCGCGGCGTGGGCTCGGACACCACCGAGAGCCGGGAGGCGCAAGCCCGCAT
CGCCTTCCTGGCGGGTCACGACAGCCTGACCGGACTGCCGAACCGCAGCGGTTTCCAGGACGCGCTGGGGACGCTCTGCC
GCGCGGTCCGCACGGCGGAGAGACCGAGTGCGCTGTTCTATCTCGACCTCGACGGCTTCAAGGCGGTCAACGACAGTCGC
GGCCACCTCGTCGGCGACCGATTGCTGCGCGCGGTCACTGCACGCCTGCTCGCCATCGGTGAACCGCACAGCCTGTTCCG
CCTCGGCGGCGACGAGTTCGCGATGGTCGTCCGCGACCTCGGTCGGCCCGCGGCCGAGGCCCTCGCCGCCCGCGTGGTGG
CCGAGCTGCGCCGCCCGTTCCAGATCGACGAGGCCCGGCTGGAGGTCGGTGTCAGCGTCGGCATCGCCTACATGCCGGAC
GACGCGGTCGAGCCTGCCAGCCTGCTCATGCGCGCCGACCTCGCCCTCTACGCCGCCAAGGCGGACGGCAAGGGCTGCTG
GCGGACCTTCGATCCGTCGCTGGAGGAGCGGGTCGTCCGCCAGCGGCAGTTCGACCTGGACATGCGCGCGGCCCTCGCGG
CGGGCGAGATGGAGCTGCACTACCAGCCCCTGGTGGACATGCGGAGCGGTCGTGTCGCCGGTTTCGAGGCGCTGCTGCGG
TGGAACAAGCCCGGGTACGGCTGGGTCTCGCCGGGGGAGATCATCCCCATCGCCGAGACGACCGGCTTCATCGTCGAGAT
CGGCCGCTGGGCCCTGCGCCGCGCCTGCACCGACGCCCGCACGTGGTCCGACCTGAAGATCGCGGTGAACATCTCCTCCA
TCCACGTGCGGATGCCGGGCTTCCACGCCGAGGTCGCGGCCGTTCTCCGCGAGACCGGCCTCGCGCCAGATCGGCTCGAG
ATCGAGATCACCGAGTCGGTGCTGCTCGACCACGGTCCGGAGGTTCTGGAAAACCTGAAGCGCCTGCGCGCGACGGGCGT
GCGCATCGCGCTGGACGACTTCGGCACGGGCTACTCGAGCCTGAGCTACCTGACCGAATTCCCGTTCGACAAGGTGAAGG
TCGACCGCTCCTTCGTGCGCGATCTGCAGGGCCGCCCCGAGAAGGTCGCCGTGGTCGAGGCCATCGCCCGAATGGCGCGG
GCCCTATCGATGAGCGTCACGGTGGAGGGCGTGGAGACCCGGCAGCAACTGGACGTCCTGCGGGACAAGCGCTGCGACAT
CGCGCAGGGCTTCCTCTACAGCCCGGCGCGCCCGGTCCACGAGGTCGCGGCACTCATCGCGCGCATCGAGGGTGCTGCGC
CGCCGCCGAGCGTGAGCGCCAGCGATCCGGACGGGAGCCCGACCGCCGACGCGCGCCCGGTCCTGTCGCTGGCCCGCGCC
TCGTAG

Upstream 100 bases:

>100_bases
AAGTCGTGCACCCTCGACAGTGCACCGACGTCGATCCAGTTCGACCTCCGCGGCAGGGTGATCGCCGCCGACGCTTCGAC
GTCCTCGAACGGGCGCGGCC

Downstream 100 bases:

>100_bases
GCGACGGGCGGCGCATCGCGTCGCCGCCGAAAGGCAGAAAACCTCTCTCGTCGCGCTGAGGACGCCCCCGGCGCGCGCTT
GCCGGGCAACGCGTCTTTAA

Product: PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 801; Mature: 800

Protein sequence:

>801_residues
MSEIILPMGVDDAAHLPDEDARLREAMRATMLAETLQLGRYSAVTQAAVVLALAAIFWGIVSHAYLSGLAVAVTALCAVA
MIAMRRYRGRLGDRSIAREAFAVLHGLALGRGLAWASMPAILLPSVDNAYRIVVGAVCAALISHAYVAGPIFSLSLLAVA
PVVAGIFVGLAGCESPVGEYVAVLLSLYAAFVFVSARRMCRHSYQRLCDRVMVQAQSETIGFLLKDFAEGTSDWLWETDT
VGRLRQARAAVAALLGVEVAGLRHRTLSELLRAFADPDGDGADAQAVAAAIAARAPFRDRTIRLRTAVGTRWITLNGKPV
FDAQGAFTGYRGVGSDTTESREAQARIAFLAGHDSLTGLPNRSGFQDALGTLCRAVRTAERPSALFYLDLDGFKAVNDSR
GHLVGDRLLRAVTARLLAIGEPHSLFRLGGDEFAMVVRDLGRPAAEALAARVVAELRRPFQIDEARLEVGVSVGIAYMPD
DAVEPASLLMRADLALYAAKADGKGCWRTFDPSLEERVVRQRQFDLDMRAALAAGEMELHYQPLVDMRSGRVAGFEALLR
WNKPGYGWVSPGEIIPIAETTGFIVEIGRWALRRACTDARTWSDLKIAVNISSIHVRMPGFHAEVAAVLRETGLAPDRLE
IEITESVLLDHGPEVLENLKRLRATGVRIALDDFGTGYSSLSYLTEFPFDKVKVDRSFVRDLQGRPEKVAVVEAIARMAR
ALSMSVTVEGVETRQQLDVLRDKRCDIAQGFLYSPARPVHEVAALIARIEGAAPPPSVSASDPDGSPTADARPVLSLARA
S

Sequences:

>Translated_801_residues
MSEIILPMGVDDAAHLPDEDARLREAMRATMLAETLQLGRYSAVTQAAVVLALAAIFWGIVSHAYLSGLAVAVTALCAVA
MIAMRRYRGRLGDRSIAREAFAVLHGLALGRGLAWASMPAILLPSVDNAYRIVVGAVCAALISHAYVAGPIFSLSLLAVA
PVVAGIFVGLAGCESPVGEYVAVLLSLYAAFVFVSARRMCRHSYQRLCDRVMVQAQSETIGFLLKDFAEGTSDWLWETDT
VGRLRQARAAVAALLGVEVAGLRHRTLSELLRAFADPDGDGADAQAVAAAIAARAPFRDRTIRLRTAVGTRWITLNGKPV
FDAQGAFTGYRGVGSDTTESREAQARIAFLAGHDSLTGLPNRSGFQDALGTLCRAVRTAERPSALFYLDLDGFKAVNDSR
GHLVGDRLLRAVTARLLAIGEPHSLFRLGGDEFAMVVRDLGRPAAEALAARVVAELRRPFQIDEARLEVGVSVGIAYMPD
DAVEPASLLMRADLALYAAKADGKGCWRTFDPSLEERVVRQRQFDLDMRAALAAGEMELHYQPLVDMRSGRVAGFEALLR
WNKPGYGWVSPGEIIPIAETTGFIVEIGRWALRRACTDARTWSDLKIAVNISSIHVRMPGFHAEVAAVLRETGLAPDRLE
IEITESVLLDHGPEVLENLKRLRATGVRIALDDFGTGYSSLSYLTEFPFDKVKVDRSFVRDLQGRPEKVAVVEAIARMAR
ALSMSVTVEGVETRQQLDVLRDKRCDIAQGFLYSPARPVHEVAALIARIEGAAPPPSVSASDPDGSPTADARPVLSLARA
S
>Mature_800_residues
SEIILPMGVDDAAHLPDEDARLREAMRATMLAETLQLGRYSAVTQAAVVLALAAIFWGIVSHAYLSGLAVAVTALCAVAM
IAMRRYRGRLGDRSIAREAFAVLHGLALGRGLAWASMPAILLPSVDNAYRIVVGAVCAALISHAYVAGPIFSLSLLAVAP
VVAGIFVGLAGCESPVGEYVAVLLSLYAAFVFVSARRMCRHSYQRLCDRVMVQAQSETIGFLLKDFAEGTSDWLWETDTV
GRLRQARAAVAALLGVEVAGLRHRTLSELLRAFADPDGDGADAQAVAAAIAARAPFRDRTIRLRTAVGTRWITLNGKPVF
DAQGAFTGYRGVGSDTTESREAQARIAFLAGHDSLTGLPNRSGFQDALGTLCRAVRTAERPSALFYLDLDGFKAVNDSRG
HLVGDRLLRAVTARLLAIGEPHSLFRLGGDEFAMVVRDLGRPAAEALAARVVAELRRPFQIDEARLEVGVSVGIAYMPDD
AVEPASLLMRADLALYAAKADGKGCWRTFDPSLEERVVRQRQFDLDMRAALAAGEMELHYQPLVDMRSGRVAGFEALLRW
NKPGYGWVSPGEIIPIAETTGFIVEIGRWALRRACTDARTWSDLKIAVNISSIHVRMPGFHAEVAAVLRETGLAPDRLEI
EITESVLLDHGPEVLENLKRLRATGVRIALDDFGTGYSSLSYLTEFPFDKVKVDRSFVRDLQGRPEKVAVVEAIARMARA
LSMSVTVEGVETRQQLDVLRDKRCDIAQGFLYSPARPVHEVAALIARIEGAAPPPSVSASDPDGSPTADARPVLSLARAS

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=460, Percent_Identity=36.7391304347826, Blast_Score=294, Evalue=1e-80,
Organism=Escherichia coli, GI87081921, Length=437, Percent_Identity=30.6636155606407, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI226510982, Length=414, Percent_Identity=28.0193236714976, Blast_Score=162, Evalue=7e-41,
Organism=Escherichia coli, GI87081845, Length=248, Percent_Identity=34.2741935483871, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1787055, Length=239, Percent_Identity=36.4016736401674, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI1788381, Length=535, Percent_Identity=27.1028037383178, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI87081980, Length=258, Percent_Identity=32.9457364341085, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1786507, Length=233, Percent_Identity=32.1888412017167, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87081743, Length=237, Percent_Identity=34.1772151898734, Blast_Score=127, Evalue=4e-30,
Organism=Escherichia coli, GI1790496, Length=238, Percent_Identity=30.2521008403361, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1788502, Length=247, Percent_Identity=29.9595141700405, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI87082096, Length=416, Percent_Identity=24.7596153846154, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1788849, Length=438, Percent_Identity=25.5707762557078, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788956, Length=160, Percent_Identity=35, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87081977, Length=162, Percent_Identity=33.9506172839506, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1787410, Length=218, Percent_Identity=24.3119266055046, Blast_Score=83, Evalue=9e-17,
Organism=Escherichia coli, GI1789650, Length=436, Percent_Identity=22.7064220183486, Blast_Score=83, Evalue=9e-17,
Organism=Escherichia coli, GI1786584, Length=211, Percent_Identity=28.436018957346, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1787262, Length=163, Percent_Identity=30.6748466257669, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787802, Length=175, Percent_Identity=30.2857142857143, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1787816, Length=158, Percent_Identity=31.0126582278481, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI87081881, Length=178, Percent_Identity=28.6516853932584, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 86541; Mature: 86409

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIILPMGVDDAAHLPDEDARLREAMRATMLAETLQLGRYSAVTQAAVVLALAAIFWGI
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VSHAYLSGLAVAVTALCAVAMIAMRRYRGRLGDRSIAREAFAVLHGLALGRGLAWASMPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCH
ILLPSVDNAYRIVVGAVCAALISHAYVAGPIFSLSLLAVAPVVAGIFVGLAGCESPVGEY
HEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VAVLLSLYAAFVFVSARRMCRHSYQRLCDRVMVQAQSETIGFLLKDFAEGTSDWLWETDT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
VGRLRQARAAVAALLGVEVAGLRHRTLSELLRAFADPDGDGADAQAVAAAIAARAPFRDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCC
TIRLRTAVGTRWITLNGKPVFDAQGAFTGYRGVGSDTTESREAQARIAFLAGHDSLTGLP
EEEEEEECCEEEEEECCEEEECCCCCCCCCCCCCCCCCCHHHHHHEEEEEECCCCCCCCC
NRSGFQDALGTLCRAVRTAERPSALFYLDLDGFKAVNDSRGHLVGDRLLRAVTARLLAIG
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
EPHSLFRLGGDEFAMVVRDLGRPAAEALAARVVAELRRPFQIDEARLEVGVSVGIAYMPD
CCHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEEECCC
DAVEPASLLMRADLALYAAKADGKGCWRTFDPSLEERVVRQRQFDLDMRAALAAGEMELH
CCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCEEE
YQPLVDMRSGRVAGFEALLRWNKPGYGWVSPGEIIPIAETTGFIVEIGRWALRRACTDAR
CCCHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC
TWSDLKIAVNISSIHVRMPGFHAEVAAVLRETGLAPDRLEIEITESVLLDHGPEVLENLK
CCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCHHHHHHHH
RLRATGVRIALDDFGTGYSSLSYLTEFPFDKVKVDRSFVRDLQGRPEKVAVVEAIARMAR
HHHHCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ALSMSVTVEGVETRQQLDVLRDKRCDIAQGFLYSPARPVHEVAALIARIEGAAPPPSVSA
HHHHHEEEECHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
SDPDGSPTADARPVLSLARAS
CCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
SEIILPMGVDDAAHLPDEDARLREAMRATMLAETLQLGRYSAVTQAAVVLALAAIFWGI
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VSHAYLSGLAVAVTALCAVAMIAMRRYRGRLGDRSIAREAFAVLHGLALGRGLAWASMPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCH
ILLPSVDNAYRIVVGAVCAALISHAYVAGPIFSLSLLAVAPVVAGIFVGLAGCESPVGEY
HEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VAVLLSLYAAFVFVSARRMCRHSYQRLCDRVMVQAQSETIGFLLKDFAEGTSDWLWETDT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
VGRLRQARAAVAALLGVEVAGLRHRTLSELLRAFADPDGDGADAQAVAAAIAARAPFRDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCC
TIRLRTAVGTRWITLNGKPVFDAQGAFTGYRGVGSDTTESREAQARIAFLAGHDSLTGLP
EEEEEEECCEEEEEECCEEEECCCCCCCCCCCCCCCCCCHHHHHHEEEEEECCCCCCCCC
NRSGFQDALGTLCRAVRTAERPSALFYLDLDGFKAVNDSRGHLVGDRLLRAVTARLLAIG
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
EPHSLFRLGGDEFAMVVRDLGRPAAEALAARVVAELRRPFQIDEARLEVGVSVGIAYMPD
CCHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEEECCC
DAVEPASLLMRADLALYAAKADGKGCWRTFDPSLEERVVRQRQFDLDMRAALAAGEMELH
CCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCEEE
YQPLVDMRSGRVAGFEALLRWNKPGYGWVSPGEIIPIAETTGFIVEIGRWALRRACTDAR
CCCHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC
TWSDLKIAVNISSIHVRMPGFHAEVAAVLRETGLAPDRLEIEITESVLLDHGPEVLENLK
CCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCHHHHHHHH
RLRATGVRIALDDFGTGYSSLSYLTEFPFDKVKVDRSFVRDLQGRPEKVAVVEAIARMAR
HHHHCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ALSMSVTVEGVETRQQLDVLRDKRCDIAQGFLYSPARPVHEVAALIARIEGAAPPPSVSA
HHHHHEEEECHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
SDPDGSPTADARPVLSLARAS
CCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]