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The map label for this gene is yciL [C]

Identifier: 170746519

GI number: 170746519

Start: 72052

End: 73857

Strand: Reverse

Name: yciL [C]

Synonym: Mrad2831_0069

Alternate gene names: 170746519

Gene position: 73857-72052 (Counterclockwise)

Preceding gene: 170746520

Following gene: 170746518

Centisome position: 1.22

GC content: 75.64

Gene sequence:

>1806_bases
ATGAGCGACTTGCCGAACGACGATAAGCCGGAGGGGACCGCCCGTCCGGCCCCCGAGTCAGCGCGCACCGAGGGTTGGGC
GCCGCCGACCGATGCGGGCCGCGCCGACACCGAGGGCGACGGGTCCGCCAAGTCCGCCGCGAAGAAGGCCGCCCGAAAGG
CCAAGCCGCAGCCTCCTCAGCAGACGGTCCCTGCGCCGGAGCCCGAACCCGCCTCGTCCGCCGACACCGAGGGCCTGATC
GAGACGCCGCCCGGCGAGCGCATCGCGAAGGCGATGGCTCGGGCTGGCATCGCCTCGCGGCGCGACGCCGAGACGATGAT
TGTGGCCGGACGCGTGAGCGTCAACGGCGAGACGCTGACGTCCCCCGCCCGCAACGTCACCGAGAACGACCGCATCCTGA
TCGATGGCGAGCCGATGCCGTCGCGGGAGCGCAGCCGCCTGTGGATCTTCCACAAGCCGCGGGGCGTGGTGACGACCGCC
CGGGATCCGGAGGGCCGGCAGACGGTGTTCGACGTGCTCCCGGAGGATCTACCCCGGGTCGTGGCTGTCGGACGGCTCGA
CATCAACACCGAGGGGCTGCTGCTCCTCACCAACGATGGTGGGCTCGCCAAGGTGATCGCGCATCCTGACACGGGCTGGC
TGCGCCGCTACCGGGTCCGCGCCCACGGCGACACCGATCAGGCCCAACTCGACCGGCTGGCCAAGGGCGTCACCATCGAC
GGGATGGAGTACGGCCCCGTCGAGGCGACGCTCGACCGGGTGCAGGGCGACAACGTCTGGCTGACACTCGGCCTGCGCGA
GGGCAAGAACCGCGAAGTCAAGCGCATCCTGGAGCATCTCGGGCTCTCGGTGAACCGGCTGATCCGGCTCTCCTTCGGGC
CGTTCCAGCTCGGCGACCTAGAAGTCGGTCTGGTCGAGGAGGTGCGGACCCGCGTGCTCAAGGATCAGCTCGGCAAGAGC
CTCGCCGAGCAGGCCGGCGTGGATTTCGACAGCCCGGTCCGCGAGCCGATCGCGCCGTTCGGCGGCACCCGCCCGGCGGA
CCGCGATGCCAAGTCCGCGCAGCCGGCGCCGGCCCGGCGCAACGCCGCGCGTCCCGCGCCGGCGCCGCGCGTCTCGACCG
GAGGCGCCGGTCCCGGACCGCGTAGCTCCACGTGGCGCGATGAGGACGCGGCGAAGCCCCGGGGCACGCGCGTGCCCCGG
CGCGGCGCGGATCCCCGGACCGCACAGGCGGCCGCGGCGGAACGCGGCCGCGAGCGCGTCGGCTCGATCCGCGCCGGTGA
GCGCCGGGTCGTCGTCGAGCGGCTGTCCGCCACACCGGCGGAGCCGGCCCCCGTCGCCAAGCCGAAGCGCCGCTTCGCCG
ACCGCGGAGCGCCGGAGCGACAGGAACGCCCCGCCGGTCCGCGCAACGAGCGCCGCGGCGACGAGCGCCCGCGTCGCGAG
ACCGCGCGGAGCGACGCACCGCGTGACGAGCGGCGATTCGACGAGCGCGGCGGCAAGTCCGGAGGACGGCGCGAACGGAC
GTTCGAGGCCGGGCCGACCGAGGGGACGTCGCGCAAGCCGGGCGGGTTCCGCGGCTCGAAGCCGGCCGGCGCTGGGGGCA
AGCCCGCGTTCGGCGGCCCGAAGACGGGGGCGCCGCGTCCCGGCGGAAGTCGCCCCGGTGGCAAGCCCGGCGGATTCACC
GGTAAGGCGGGCGGCCAGGGCACGCGCAGCGGCCCGGGCGGCGGCCCGAGCGCGGGCGGCCGTCCCGGTGCGCCGCGCGG
CGGCGCCCGGCCCGGCGGCGGCAGGCCGCCCCGCGGGACGCGATGA

Upstream 100 bases:

>100_bases
TTCGAGGCGGTCCCAGCGGGCCGCCTCTTTGCGTTGAGGGCACCTGCCCCCGTGCACAACCCGTCTCGCCTGTCGAGACC
GGCTCTGATAAGCGGCAAGC

Downstream 100 bases:

>100_bases
GGATCGTCGGCGGCGCGTGGCGAGGCCGCCGGCTTGCCGCGCCGCGCACCGACGCCATCCGGCCGACCTCGGACCGGCTG
CGCGAGTCGGTGTTCAACGT

Product: RNA-binding S4 domain-containing protein

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MSDLPNDDKPEGTARPAPESARTEGWAPPTDAGRADTEGDGSAKSAAKKAARKAKPQPPQQTVPAPEPEPASSADTEGLI
ETPPGERIAKAMARAGIASRRDAETMIVAGRVSVNGETLTSPARNVTENDRILIDGEPMPSRERSRLWIFHKPRGVVTTA
RDPEGRQTVFDVLPEDLPRVVAVGRLDINTEGLLLLTNDGGLAKVIAHPDTGWLRRYRVRAHGDTDQAQLDRLAKGVTID
GMEYGPVEATLDRVQGDNVWLTLGLREGKNREVKRILEHLGLSVNRLIRLSFGPFQLGDLEVGLVEEVRTRVLKDQLGKS
LAEQAGVDFDSPVREPIAPFGGTRPADRDAKSAQPAPARRNAARPAPAPRVSTGGAGPGPRSSTWRDEDAAKPRGTRVPR
RGADPRTAQAAAAERGRERVGSIRAGERRVVVERLSATPAEPAPVAKPKRRFADRGAPERQERPAGPRNERRGDERPRRE
TARSDAPRDERRFDERGGKSGGRRERTFEAGPTEGTSRKPGGFRGSKPAGAGGKPAFGGPKTGAPRPGGSRPGGKPGGFT
GKAGGQGTRSGPGGGPSAGGRPGAPRGGARPGGGRPPRGTR

Sequences:

>Translated_601_residues
MSDLPNDDKPEGTARPAPESARTEGWAPPTDAGRADTEGDGSAKSAAKKAARKAKPQPPQQTVPAPEPEPASSADTEGLI
ETPPGERIAKAMARAGIASRRDAETMIVAGRVSVNGETLTSPARNVTENDRILIDGEPMPSRERSRLWIFHKPRGVVTTA
RDPEGRQTVFDVLPEDLPRVVAVGRLDINTEGLLLLTNDGGLAKVIAHPDTGWLRRYRVRAHGDTDQAQLDRLAKGVTID
GMEYGPVEATLDRVQGDNVWLTLGLREGKNREVKRILEHLGLSVNRLIRLSFGPFQLGDLEVGLVEEVRTRVLKDQLGKS
LAEQAGVDFDSPVREPIAPFGGTRPADRDAKSAQPAPARRNAARPAPAPRVSTGGAGPGPRSSTWRDEDAAKPRGTRVPR
RGADPRTAQAAAAERGRERVGSIRAGERRVVVERLSATPAEPAPVAKPKRRFADRGAPERQERPAGPRNERRGDERPRRE
TARSDAPRDERRFDERGGKSGGRRERTFEAGPTEGTSRKPGGFRGSKPAGAGGKPAFGGPKTGAPRPGGSRPGGKPGGFT
GKAGGQGTRSGPGGGPSAGGRPGAPRGGARPGGGRPPRGTR
>Mature_600_residues
SDLPNDDKPEGTARPAPESARTEGWAPPTDAGRADTEGDGSAKSAAKKAARKAKPQPPQQTVPAPEPEPASSADTEGLIE
TPPGERIAKAMARAGIASRRDAETMIVAGRVSVNGETLTSPARNVTENDRILIDGEPMPSRERSRLWIFHKPRGVVTTAR
DPEGRQTVFDVLPEDLPRVVAVGRLDINTEGLLLLTNDGGLAKVIAHPDTGWLRRYRVRAHGDTDQAQLDRLAKGVTIDG
MEYGPVEATLDRVQGDNVWLTLGLREGKNREVKRILEHLGLSVNRLIRLSFGPFQLGDLEVGLVEEVRTRVLKDQLGKSL
AEQAGVDFDSPVREPIAPFGGTRPADRDAKSAQPAPARRNAARPAPAPRVSTGGAGPGPRSSTWRDEDAAKPRGTRVPRR
GADPRTAQAAAAERGRERVGSIRAGERRVVVERLSATPAEPAPVAKPKRRFADRGAPERQERPAGPRNERRGDERPRRET
ARSDAPRDERRFDERGGKSGGRRERTFEAGPTEGTSRKPGGFRGSKPAGAGGKPAFGGPKTGAPRPGGSRPGGKPGGFTG
KAGGQGTRSGPGGGPSAGGRPGAPRGGARPGGGRPPRGTR

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=221, Percent_Identity=43.8914027149321, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI87081838, Length=184, Percent_Identity=33.1521739130435, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790453, Length=211, Percent_Identity=30.8056872037915, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788510, Length=212, Percent_Identity=30.188679245283, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 63711; Mature: 63580

Theoretical pI: Translated: 11.40; Mature: 11.40

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLPNDDKPEGTARPAPESARTEGWAPPTDAGRADTEGDGSAKSAAKKAARKAKPQPPQ
CCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
QTVPAPEPEPASSADTEGLIETPPGERIAKAMARAGIASRRDAETMIVAGRVSVNGETLT
CCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCC
SPARNVTENDRILIDGEPMPSRERSRLWIFHKPRGVVTTARDPEGRQTVFDVLPEDLPRV
CCCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCEEECCCCCCHHHHHHHHCHHHHHHH
VAVGRLDINTEGLLLLTNDGGLAKVIAHPDTGWLRRYRVRAHGDTDQAQLDRLAKGVTID
EEECEEEECCCCEEEEECCCCEEEEEECCCHHHHHHHHHEECCCCCHHHHHHHHCCCEEC
GMEYGPVEATLDRVQGDNVWLTLGLREGKNREVKRILEHLGLSVNRLIRLSFGPFQLGDL
CCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHEEEECCCCCEECCC
EVGLVEEVRTRVLKDQLGKSLAEQAGVDFDSPVREPIAPFGGTRPADRDAKSAQPAPARR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
NAARPAPAPRVSTGGAGPGPRSSTWRDEDAAKPRGTRVPRRGADPRTAQAAAAERGRERV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GSIRAGERRVVVERLSATPAEPAPVAKPKRRFADRGAPERQERPAGPRNERRGDERPRRE
HCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHCCCCCCHHCCCCCHHHHH
TARSDAPRDERRFDERGGKSGGRRERTFEAGPTEGTSRKPGGFRGSKPAGAGGKPAFGGP
HHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KTGAPRPGGSRPGGKPGGFTGKAGGQGTRSGPGGGPSAGGRPGAPRGGARPGGGRPPRGT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
R
C
>Mature Secondary Structure 
SDLPNDDKPEGTARPAPESARTEGWAPPTDAGRADTEGDGSAKSAAKKAARKAKPQPPQ
CCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
QTVPAPEPEPASSADTEGLIETPPGERIAKAMARAGIASRRDAETMIVAGRVSVNGETLT
CCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCC
SPARNVTENDRILIDGEPMPSRERSRLWIFHKPRGVVTTARDPEGRQTVFDVLPEDLPRV
CCCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCEEECCCCCCHHHHHHHHCHHHHHHH
VAVGRLDINTEGLLLLTNDGGLAKVIAHPDTGWLRRYRVRAHGDTDQAQLDRLAKGVTID
EEECEEEECCCCEEEEECCCCEEEEEECCCHHHHHHHHHEECCCCCHHHHHHHHCCCEEC
GMEYGPVEATLDRVQGDNVWLTLGLREGKNREVKRILEHLGLSVNRLIRLSFGPFQLGDL
CCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHEEEECCCCCEECCC
EVGLVEEVRTRVLKDQLGKSLAEQAGVDFDSPVREPIAPFGGTRPADRDAKSAQPAPARR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
NAARPAPAPRVSTGGAGPGPRSSTWRDEDAAKPRGTRVPRRGADPRTAQAAAAERGRERV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GSIRAGERRVVVERLSATPAEPAPVAKPKRRFADRGAPERQERPAGPRNERRGDERPRRE
HCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHCCCCCCHHCCCCCHHHHH
TARSDAPRDERRFDERGGKSGGRRERTFEAGPTEGTSRKPGGFRGSKPAGAGGKPAFGGP
HHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KTGAPRPGGSRPGGKPGGFTGKAGGQGTRSGPGGGPSAGGRPGAPRGGARPGGGRPPRGT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA