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The map label for this gene is exoB [H]

Identifier: 170746490

GI number: 170746490

Start: 47114

End: 48106

Strand: Reverse

Name: exoB [H]

Synonym: Mrad2831_0040

Alternate gene names: 170746490

Gene position: 48106-47114 (Counterclockwise)

Preceding gene: 170746492

Following gene: 170746489

Centisome position: 0.79

GC content: 69.69

Gene sequence:

>993_bases
ATGGCGGTTCTGGTGACGGGTGGTGCCGGCTACATCGGCAGCCACATGGTGCTGGCGCTCCTCGACGCCGGCCATGAGGA
GGTCGTCGTCCTGGACGATCTGTCCACCGGTTTCGACTGGGCGGTCCCGGAGGGCGTGAAGCTCGTCGTCGGCGACGTGG
CCGACCAAGCCCTCGTGACGCAGACGATCCTCCAGCACCGCATCGACGCCCTGGCCCATTTCGCCGCCAAGATCGTCGTG
CCCGATTCCGTAGCCGATCCCCTGGGCTACTACCTGGCCAACACGGTGAAGACCCGCTCGCTGATCGAGGCCGCGGTACG
CGCCGGCGTCAAGCACGTGATCTTCTCCTCGACCGCGGCCGTCTACGGCGAGCCCGACGTCACGCCGGTTCCCGAGGATC
TGCCGCTCAACCCGATCAACCCCTACGGCCGCTCGAAGCTGATGAGCGAGTGGATGATCGCCGACGCCGCCGCGGCGCAC
GGCTTCTCCTACGTGGTCCTGCGCTACTTCAACGTCGCCGGCGCAGATCCGGAGGGGCGGTCCGGCCAGTCGACGCCGAA
TGCCACACACCTCATCAAGGTGGCCACCCAGGCGGCGCTCGGACAGCGCGCCCGGCTCGACGTCTTCGGGACCGACTACC
CGACCCCGGACGGGTCGTGCCTGCGCGACTACATCCAGGTGTCGGACCTCGCCGAGGCGCATCGCCTCGCCCTCGACCAC
CTGCGCTCCGGCGGCGAGAGCCTGACGCTGAACTGCGGCTACGGGCGCGGCTACTCGGTGCTCGAGGTGGTCGAGGTCGT
GAAGCGGATCTCCGGCCGCGATTTCGAGGTGCGCCTGTGCCCGCGCCGAGCCGGCGATCCGGCCCAGATCGTCGCCGAGG
CGGCGCGCATCCGCGAGCGCCTGGGGTGGCAGCCCCGGCACGACGACCTCGACGCCATCGTCGACCAGGCGCTCGCCTGG
GAACAGCGCCTGGAGAAGCGCAATCGGATCTGA

Upstream 100 bases:

>100_bases
CCGTTGCAAGCATGTACGTCGATAGTATGAGGTGGCGGGGCGTAAATTTCCCGTCTGCAAAAGCGTATGCCGGTGCCGGG
GTGGGGGCAGAGGGGGTGAG

Downstream 100 bases:

>100_bases
CCGGATGCTCTCCCGCCGATGGTTTCTGGCCGCGGCGGCGTCCCTCGCCACCGGGGAGGCCCGCGCCGAGGACGCCTTCC
GGGCGTTCATCGAGGCCCTG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MAVLVTGGAGYIGSHMVLALLDAGHEEVVVLDDLSTGFDWAVPEGVKLVVGDVADQALVTQTILQHRIDALAHFAAKIVV
PDSVADPLGYYLANTVKTRSLIEAAVRAGVKHVIFSSTAAVYGEPDVTPVPEDLPLNPINPYGRSKLMSEWMIADAAAAH
GFSYVVLRYFNVAGADPEGRSGQSTPNATHLIKVATQAALGQRARLDVFGTDYPTPDGSCLRDYIQVSDLAEAHRLALDH
LRSGGESLTLNCGYGRGYSVLEVVEVVKRISGRDFEVRLCPRRAGDPAQIVAEAARIRERLGWQPRHDDLDAIVDQALAW
EQRLEKRNRI

Sequences:

>Translated_330_residues
MAVLVTGGAGYIGSHMVLALLDAGHEEVVVLDDLSTGFDWAVPEGVKLVVGDVADQALVTQTILQHRIDALAHFAAKIVV
PDSVADPLGYYLANTVKTRSLIEAAVRAGVKHVIFSSTAAVYGEPDVTPVPEDLPLNPINPYGRSKLMSEWMIADAAAAH
GFSYVVLRYFNVAGADPEGRSGQSTPNATHLIKVATQAALGQRARLDVFGTDYPTPDGSCLRDYIQVSDLAEAHRLALDH
LRSGGESLTLNCGYGRGYSVLEVVEVVKRISGRDFEVRLCPRRAGDPAQIVAEAARIRERLGWQPRHDDLDAIVDQALAW
EQRLEKRNRI
>Mature_329_residues
AVLVTGGAGYIGSHMVLALLDAGHEEVVVLDDLSTGFDWAVPEGVKLVVGDVADQALVTQTILQHRIDALAHFAAKIVVP
DSVADPLGYYLANTVKTRSLIEAAVRAGVKHVIFSSTAAVYGEPDVTPVPEDLPLNPINPYGRSKLMSEWMIADAAAAHG
FSYVVLRYFNVAGADPEGRSGQSTPNATHLIKVATQAALGQRARLDVFGTDYPTPDGSCLRDYIQVSDLAEAHRLALDHL
RSGGESLTLNCGYGRGYSVLEVVEVVKRISGRDFEVRLCPRRAGDPAQIVAEAARIRERLGWQPRHDDLDAIVDQALAWE
QRLEKRNRI

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=339, Percent_Identity=38.9380530973451, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI56118217, Length=339, Percent_Identity=38.9380530973451, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI189083684, Length=339, Percent_Identity=38.9380530973451, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI42516563, Length=313, Percent_Identity=28.4345047923323, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI7657641, Length=318, Percent_Identity=27.0440251572327, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI1786974, Length=335, Percent_Identity=39.7014925373134, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1788353, Length=355, Percent_Identity=25.6338028169014, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994969, Length=350, Percent_Identity=24.8571428571429, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71982038, Length=346, Percent_Identity=34.6820809248555, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71982035, Length=325, Percent_Identity=36, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17568069, Length=331, Percent_Identity=28.7009063444109, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17539532, Length=338, Percent_Identity=24.5562130177515, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319493, Length=322, Percent_Identity=36.6459627329193, Blast_Score=197, Evalue=3e-51,
Organism=Drosophila melanogaster, GI19923002, Length=341, Percent_Identity=38.7096774193548, Blast_Score=218, Evalue=4e-57,
Organism=Drosophila melanogaster, GI21356223, Length=314, Percent_Identity=27.3885350318471, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35753; Mature: 35622

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLVTGGAGYIGSHMVLALLDAGHEEVVVLDDLSTGFDWAVPEGVKLVVGDVADQALVT
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHH
QTILQHRIDALAHFAAKIVVPDSVADPLGYYLANTVKTRSLIEAAVRAGVKHVIFSSTAA
HHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VYGEPDVTPVPEDLPLNPINPYGRSKLMSEWMIADAAAAHGFSYVVLRYFNVAGADPEGR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC
SGQSTPNATHLIKVATQAALGQRARLDVFGTDYPTPDGSCLRDYIQVSDLAEAHRLALDH
CCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LRSGGESLTLNCGYGRGYSVLEVVEVVKRISGRDFEVRLCPRRAGDPAQIVAEAARIRER
HHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
LGWQPRHDDLDAIVDQALAWEQRLEKRNRI
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVLVTGGAGYIGSHMVLALLDAGHEEVVVLDDLSTGFDWAVPEGVKLVVGDVADQALVT
EEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHH
QTILQHRIDALAHFAAKIVVPDSVADPLGYYLANTVKTRSLIEAAVRAGVKHVIFSSTAA
HHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VYGEPDVTPVPEDLPLNPINPYGRSKLMSEWMIADAAAAHGFSYVVLRYFNVAGADPEGR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC
SGQSTPNATHLIKVATQAALGQRARLDVFGTDYPTPDGSCLRDYIQVSDLAEAHRLALDH
CCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LRSGGESLTLNCGYGRGYSVLEVVEVVKRISGRDFEVRLCPRRAGDPAQIVAEAARIRER
HHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
LGWQPRHDDLDAIVDQALAWEQRLEKRNRI
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]